Anton Goloborodko
@golobor.bsky.social
A bio-physicist turned phys-biologist,
building models and software in genome biology.
3D genome structure in mitosis | DNA repair | meiosis.
A group leader at @IMBA_Vienna.
Dad x2.
building models and software in genome biology.
3D genome structure in mitosis | DNA repair | meiosis.
A group leader at @IMBA_Vienna.
Dad x2.
Pinned
Anton Goloborodko
@golobor.bsky.social
· Jul 15
We found a new asymmetry in the large-scale chromosome structure: sister chromatids are systematically shifted by hundreds of kb in the 5′→3′ direction of their inherited strands! The work was led by Flavia Corsi, in close collaboration with the Daniel Gerlich lab.
www.biorxiv.org/content/10.1...
1/
www.biorxiv.org/content/10.1...
1/
Reposted by Anton Goloborodko
Great career opportunity at @viennabiocenter.bsky.social: The @impvienna.bsky.social is looking for a new Junior Group Leader in cell and molecular biology, synthetic biology, genomics, gene regulation, development, cancer, immunology or infection biology.
More: www.imp.ac.at/career/open-...
More: www.imp.ac.at/career/open-...
Junior Group Leader Positions | Research Institute of Molecular Pathology
www.imp.ac.at
November 10, 2025 at 10:49 AM
Great career opportunity at @viennabiocenter.bsky.social: The @impvienna.bsky.social is looking for a new Junior Group Leader in cell and molecular biology, synthetic biology, genomics, gene regulation, development, cancer, immunology or infection biology.
More: www.imp.ac.at/career/open-...
More: www.imp.ac.at/career/open-...
Reposted by Anton Goloborodko
🌍Open call: Junior Group Leader positions!
Join a world-class biomedical research institute at the heart of the Vienna BioCenter, where curiosity drives discovery.
Lead your own lab, pursue bold ideas, and shape the future of science at the IMP: www.imp.ac.at/career/open-...
Join a world-class biomedical research institute at the heart of the Vienna BioCenter, where curiosity drives discovery.
Lead your own lab, pursue bold ideas, and shape the future of science at the IMP: www.imp.ac.at/career/open-...
November 10, 2025 at 1:26 PM
🌍Open call: Junior Group Leader positions!
Join a world-class biomedical research institute at the heart of the Vienna BioCenter, where curiosity drives discovery.
Lead your own lab, pursue bold ideas, and shape the future of science at the IMP: www.imp.ac.at/career/open-...
Join a world-class biomedical research institute at the heart of the Vienna BioCenter, where curiosity drives discovery.
Lead your own lab, pursue bold ideas, and shape the future of science at the IMP: www.imp.ac.at/career/open-...
Reposted by Anton Goloborodko
The Wilkinson Lab is open for science! @mskcancercenter.bsky.social
🧬We'll be finding funky new RNA biology, mainly by looking at reverse transcriptases (i.e. the Best Enzymes In The World)🧬
annnd: I'm hiring - come join! Especially postdocs and PhD students - please get in touch (NYC is great)
🧬We'll be finding funky new RNA biology, mainly by looking at reverse transcriptases (i.e. the Best Enzymes In The World)🧬
annnd: I'm hiring - come join! Especially postdocs and PhD students - please get in touch (NYC is great)
Wilkinson Lab
We discover and study reverse transcriptases
wilkinsonlab.bio
October 31, 2025 at 7:00 PM
The Wilkinson Lab is open for science! @mskcancercenter.bsky.social
🧬We'll be finding funky new RNA biology, mainly by looking at reverse transcriptases (i.e. the Best Enzymes In The World)🧬
annnd: I'm hiring - come join! Especially postdocs and PhD students - please get in touch (NYC is great)
🧬We'll be finding funky new RNA biology, mainly by looking at reverse transcriptases (i.e. the Best Enzymes In The World)🧬
annnd: I'm hiring - come join! Especially postdocs and PhD students - please get in touch (NYC is great)
Reposted by Anton Goloborodko
🚨Excited to kick off our online seminar series on Metabolism in Development and Physiology!
Please help us grow a collaborative and supportive community by joining (<1min): forms.gle/Y8QzucogKKrZ...
#Metabolism #Development #StemCells
Please RT! 🙏
Please help us grow a collaborative and supportive community by joining (<1min): forms.gle/Y8QzucogKKrZ...
#Metabolism #Development #StemCells
Please RT! 🙏
October 28, 2025 at 4:39 PM
🚨Excited to kick off our online seminar series on Metabolism in Development and Physiology!
Please help us grow a collaborative and supportive community by joining (<1min): forms.gle/Y8QzucogKKrZ...
#Metabolism #Development #StemCells
Please RT! 🙏
Please help us grow a collaborative and supportive community by joining (<1min): forms.gle/Y8QzucogKKrZ...
#Metabolism #Development #StemCells
Please RT! 🙏
Reposted by Anton Goloborodko
Absolute must-read thread.
also this is one of the funniest papers you will ever read, both in itself and on the meta level of just how bitchy it is
October 24, 2025 at 5:36 PM
Absolute must-read thread.
Reposted by Anton Goloborodko
Update: the mustard seeds have joined the cumin seeds in the reticulum
October 18, 2025 at 3:59 PM
Update: the mustard seeds have joined the cumin seeds in the reticulum
Reposted by Anton Goloborodko
Excited to share our paper on dynamics of microcompartments during M-to-G1 is now published in @natsmb.nature.com www.nature.com/articles/s41...
Compared to biorxiv, published includes new analysis from James Jusuf and Viraat Goel (from @andersshansen.bsky.social lab) on transcriptional spiking
Compared to biorxiv, published includes new analysis from James Jusuf and Viraat Goel (from @andersshansen.bsky.social lab) on transcriptional spiking
October 17, 2025 at 2:58 PM
Excited to share our paper on dynamics of microcompartments during M-to-G1 is now published in @natsmb.nature.com www.nature.com/articles/s41...
Compared to biorxiv, published includes new analysis from James Jusuf and Viraat Goel (from @andersshansen.bsky.social lab) on transcriptional spiking
Compared to biorxiv, published includes new analysis from James Jusuf and Viraat Goel (from @andersshansen.bsky.social lab) on transcriptional spiking
Reposted by Anton Goloborodko
ISTA @istaresearch.bsky.social is hiring a tenure-track staff scientist in Computational Structural Biology, to develop tools for cryo-EM, cryo-ET, structural prediction methods and protein interaction analysis!
Please spread the word!
ista.ac.at/en/job/tenur...
Please spread the word!
ista.ac.at/en/job/tenur...
Tenure-based Research Staff Scientist Position in Computational Structural Biology
ISTA (www.ista.ac.at) is seeking a highly skilled Staff Scientist in Computational Structural Biology to support and advance the Institute’s structural biology research through the development and imp...
ista.ac.at
October 15, 2025 at 2:08 PM
ISTA @istaresearch.bsky.social is hiring a tenure-track staff scientist in Computational Structural Biology, to develop tools for cryo-EM, cryo-ET, structural prediction methods and protein interaction analysis!
Please spread the word!
ista.ac.at/en/job/tenur...
Please spread the word!
ista.ac.at/en/job/tenur...
Reposted by Anton Goloborodko
Paper alert! doi.org/10.1038/s443... - "A scheduler for rhythmic gene expression". We show how 9 txn factors suffice for rhythmic gene expression of thousands of genes with any phase or amplitude in #Celegans larvae (and also look at the tissues where oscillations happen) 1/n
October 10, 2025 at 2:17 PM
Paper alert! doi.org/10.1038/s443... - "A scheduler for rhythmic gene expression". We show how 9 txn factors suffice for rhythmic gene expression of thousands of genes with any phase or amplitude in #Celegans larvae (and also look at the tissues where oscillations happen) 1/n
Reposted by Anton Goloborodko
Off he is ...
Ulrich is one of the most remarkable scientists I had the pleasure to work with. I learned so much from him about biochemistry, proteins, structural biology, and so much more.
Great people make great things happen.
The really great people are rare.
Ulrich is one of them ...
Ulrich is one of the most remarkable scientists I had the pleasure to work with. I learned so much from him about biochemistry, proteins, structural biology, and so much more.
Great people make great things happen.
The really great people are rare.
Ulrich is one of them ...
Thrilled to share that I’ll be joining @imbmainz.bsky.social in February 2026 to start my own group!
We will explore new mechanisms in eukaryotic gene expression, leveraging ‘evolutionary play’ to uncover how regulation, repurposing, and hijacking shape RNA biology.
PhD positions available!
We will explore new mechanisms in eukaryotic gene expression, leveraging ‘evolutionary play’ to uncover how regulation, repurposing, and hijacking shape RNA biology.
PhD positions available!
October 12, 2025 at 9:15 PM
Off he is ...
Ulrich is one of the most remarkable scientists I had the pleasure to work with. I learned so much from him about biochemistry, proteins, structural biology, and so much more.
Great people make great things happen.
The really great people are rare.
Ulrich is one of them ...
Ulrich is one of the most remarkable scientists I had the pleasure to work with. I learned so much from him about biochemistry, proteins, structural biology, and so much more.
Great people make great things happen.
The really great people are rare.
Ulrich is one of them ...
Reposted by Anton Goloborodko
Connecting different “neighborhoods” of a genome has many benefits. For one, it can allow a gene to be regulated by multiple sources, increasing the possibility for more complexity.
Loops of DNA Equipped Ancient Life To Become Complex | Quanta Magazine
New work shows that physical folding of the genome to control genes located far away may have been an early evolutionary development.
www.quantamagazine.org
October 10, 2025 at 8:04 PM
Connecting different “neighborhoods” of a genome has many benefits. For one, it can allow a gene to be regulated by multiple sources, increasing the possibility for more complexity.
Reposted by Anton Goloborodko
I am hiring! - looking for a Staff Scientist to co-run my research group with me. Staff Scientist is a senior professional scientist role at EMBL. Please forward to people you might know who could be interested! embl.wd103.myworkdayjobs.com/en-US/EMBL/j...
Staff Scientist
About EMBL-EBI EMBL’s European Bioinformatics Institute is a data powerhouse, utilised on a global scale to advance scientific discovery through bioinformatics and solutions to some of the world’s mos...
embl.wd103.myworkdayjobs.com
October 10, 2025 at 7:30 AM
I am hiring! - looking for a Staff Scientist to co-run my research group with me. Staff Scientist is a senior professional scientist role at EMBL. Please forward to people you might know who could be interested! embl.wd103.myworkdayjobs.com/en-US/EMBL/j...
Reposted by Anton Goloborodko
How do SMC complexes load onto DNA to get ready for loop extrusion?
@roisnehamelinf.bsky.social & co discovered that Wadjet, an SMC complex involved in bacterial DNA immunity, performs some impressive molecular gymnastics 🤸♂️🤸♂️🤸♂️.
Check out the new paper: www.cell.com/molecular-ce...
@roisnehamelinf.bsky.social & co discovered that Wadjet, an SMC complex involved in bacterial DNA immunity, performs some impressive molecular gymnastics 🤸♂️🤸♂️🤸♂️.
Check out the new paper: www.cell.com/molecular-ce...
October 9, 2025 at 2:43 PM
How do SMC complexes load onto DNA to get ready for loop extrusion?
@roisnehamelinf.bsky.social & co discovered that Wadjet, an SMC complex involved in bacterial DNA immunity, performs some impressive molecular gymnastics 🤸♂️🤸♂️🤸♂️.
Check out the new paper: www.cell.com/molecular-ce...
@roisnehamelinf.bsky.social & co discovered that Wadjet, an SMC complex involved in bacterial DNA immunity, performs some impressive molecular gymnastics 🤸♂️🤸♂️🤸♂️.
Check out the new paper: www.cell.com/molecular-ce...
once-in-a-lifetime opportunity!!
Now that I'm settled in at @umasschan.bsky.social, I'm hiring at all levels: grad students, post-docs, and software engineers/bioinformaticians!
The goal of my lab is to understand the regulatory role of every nucleotide in our genomes and how this changes across every cell in our bodies.
The goal of my lab is to understand the regulatory role of every nucleotide in our genomes and how this changes across every cell in our bodies.
October 9, 2025 at 2:55 PM
once-in-a-lifetime opportunity!!
Reposted by Anton Goloborodko
The Vienna BioCenter PhD Program application deadline is approaching: October 10!
Join one of Europe’s premier life science campuses, home to cutting-edge research across all areas of biology.
Apply and start your scientific journey in Vienna!
training.vbc.ac.at/phd-program/
#PhD #LifeSciences
Join one of Europe’s premier life science campuses, home to cutting-edge research across all areas of biology.
Apply and start your scientific journey in Vienna!
training.vbc.ac.at/phd-program/
#PhD #LifeSciences
October 5, 2025 at 9:35 AM
The Vienna BioCenter PhD Program application deadline is approaching: October 10!
Join one of Europe’s premier life science campuses, home to cutting-edge research across all areas of biology.
Apply and start your scientific journey in Vienna!
training.vbc.ac.at/phd-program/
#PhD #LifeSciences
Join one of Europe’s premier life science campuses, home to cutting-edge research across all areas of biology.
Apply and start your scientific journey in Vienna!
training.vbc.ac.at/phd-program/
#PhD #LifeSciences
Reposted by Anton Goloborodko
Passionate about #SystemsBiology and ready to lead your own research group?
Join us at the forefront of discovery — apply now to be a #GroupLeader at the NOVA Institute for Medical Systems Biology, in beautiful Lisbon, PT!
Appl. by Oct 8:
www.nature.com/naturecareer...
#ScienceJobs #JobOffer
Join us at the forefront of discovery — apply now to be a #GroupLeader at the NOVA Institute for Medical Systems Biology, in beautiful Lisbon, PT!
Appl. by Oct 8:
www.nature.com/naturecareer...
#ScienceJobs #JobOffer
September 29, 2025 at 9:52 AM
Passionate about #SystemsBiology and ready to lead your own research group?
Join us at the forefront of discovery — apply now to be a #GroupLeader at the NOVA Institute for Medical Systems Biology, in beautiful Lisbon, PT!
Appl. by Oct 8:
www.nature.com/naturecareer...
#ScienceJobs #JobOffer
Join us at the forefront of discovery — apply now to be a #GroupLeader at the NOVA Institute for Medical Systems Biology, in beautiful Lisbon, PT!
Appl. by Oct 8:
www.nature.com/naturecareer...
#ScienceJobs #JobOffer
Reposted by Anton Goloborodko
BREAKING: Elon Musk just became first person in history to hit $500 billion in net worth.
October 2, 2025 at 1:42 AM
BREAKING: Elon Musk just became first person in history to hit $500 billion in net worth.
Reposted by Anton Goloborodko
Paris-Berlin sleeper: low carbon, 2 years old, constantly full, but currently losing SNCF a few million EUR/yr
Intl Jet fuel tax exemptions are 80 years old and cost the EU 22 million EUR/yr for the Paris-Berlin route alone.
And you're cutting... the sleeper?
www.theguardian.com/travel/2025/...
Intl Jet fuel tax exemptions are 80 years old and cost the EU 22 million EUR/yr for the Paris-Berlin route alone.
And you're cutting... the sleeper?
www.theguardian.com/travel/2025/...
It’s goodnight Vienna as Paris sleeper train to Austria and Berlin hit by cuts
Some Nightjet services suspended from mid-December after French withdrawal amid public budget crisis
www.theguardian.com
September 29, 2025 at 9:31 PM
Paris-Berlin sleeper: low carbon, 2 years old, constantly full, but currently losing SNCF a few million EUR/yr
Intl Jet fuel tax exemptions are 80 years old and cost the EU 22 million EUR/yr for the Paris-Berlin route alone.
And you're cutting... the sleeper?
www.theguardian.com/travel/2025/...
Intl Jet fuel tax exemptions are 80 years old and cost the EU 22 million EUR/yr for the Paris-Berlin route alone.
And you're cutting... the sleeper?
www.theguardian.com/travel/2025/...
Reposted by Anton Goloborodko
Assistant/Associate Professor in Structural Biology, Biophysics or Biological Imaging
www.biozentrum.unibas.ch/open-positio...
#biozentrum #University #Basel #Professor #Structural #Biology #Biophysics #Biological #Imaging
www.biozentrum.unibas.ch/open-positio...
#biozentrum #University #Basel #Professor #Structural #Biology #Biophysics #Biological #Imaging
September 29, 2025 at 2:58 PM
Assistant/Associate Professor in Structural Biology, Biophysics or Biological Imaging
www.biozentrum.unibas.ch/open-positio...
#biozentrum #University #Basel #Professor #Structural #Biology #Biophysics #Biological #Imaging
www.biozentrum.unibas.ch/open-positio...
#biozentrum #University #Basel #Professor #Structural #Biology #Biophysics #Biological #Imaging
Reposted by Anton Goloborodko
New preprint from the lab !! Loop extrusion may provide mechanical robustness to chromatin. Great work by Hossein Salari. @cnrs.fr @lbmcinlyon.bsky.social
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Loop extrusion provides mechanical robustness to chromatin
Chromosomes are complex biopolymers folded into dynamic loops via a loop extrusion process and may experience various mechanical forces in vivo . We develop a force-dependent model of chromatin loop e...
www.biorxiv.org
September 29, 2025 at 1:24 PM
New preprint from the lab !! Loop extrusion may provide mechanical robustness to chromatin. Great work by Hossein Salari. @cnrs.fr @lbmcinlyon.bsky.social
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Anton Goloborodko
Do you like theoretical biology, mathematical&conceptual modelling and want to apply yourself to cutting-edge research at all levels of biology, from molecules to ecosystems?
Come to EMBL! Scope includes physics-based models, emergence, statistics, ML/AI
embl.wd103.myworkdayjobs.com/en-US/EMBL/j...
Come to EMBL! Scope includes physics-based models, emergence, statistics, ML/AI
embl.wd103.myworkdayjobs.com/en-US/EMBL/j...
September 29, 2025 at 7:03 AM
Do you like theoretical biology, mathematical&conceptual modelling and want to apply yourself to cutting-edge research at all levels of biology, from molecules to ecosystems?
Come to EMBL! Scope includes physics-based models, emergence, statistics, ML/AI
embl.wd103.myworkdayjobs.com/en-US/EMBL/j...
Come to EMBL! Scope includes physics-based models, emergence, statistics, ML/AI
embl.wd103.myworkdayjobs.com/en-US/EMBL/j...
Reposted by Anton Goloborodko
I am super excited to announce that we have a tenure-track faculty position in biophysics open in the Department of Physics at Carnegie Mellon! 🧪
Interfolio link: apply.interfolio.com/174360
PLEASE, share widely across the blue skies!
Let me briefly explain what we're looking for:
1/10
Interfolio link: apply.interfolio.com/174360
PLEASE, share widely across the blue skies!
Let me briefly explain what we're looking for:
1/10
September 26, 2025 at 3:35 PM
I am super excited to announce that we have a tenure-track faculty position in biophysics open in the Department of Physics at Carnegie Mellon! 🧪
Interfolio link: apply.interfolio.com/174360
PLEASE, share widely across the blue skies!
Let me briefly explain what we're looking for:
1/10
Interfolio link: apply.interfolio.com/174360
PLEASE, share widely across the blue skies!
Let me briefly explain what we're looking for:
1/10
Reposted by Anton Goloborodko
Join us at the Hubrecht Institute in Utrecht to start your research group! Fantastic scientific environment, strong support, and nice colleagues :) Apply and please share broadly in your network.
Ready to establish your own research group at the Hubrecht Institute for Molecular and Developmental Biology? We’re seeking a tenure-track group leader to develop an innovative research line within our vibrant scientific community. Learn more & apply! https://f.mtr.cool/jncxfqkuds
September 28, 2025 at 9:43 AM
Join us at the Hubrecht Institute in Utrecht to start your research group! Fantastic scientific environment, strong support, and nice colleagues :) Apply and please share broadly in your network.
This hypothesis provides a (potential) explanation to many paradoxes and confusions in the field of enhancer-promoter interactions. An absolute must read!!
Really excited to share our latest work led by @mattiaubertini.bsky.social and @nesslfy.bsky.social: we report that cohesin loop extrusion creates rare but long-lived encounters between genomic sequences which underlie efficient enhancer-promoter communication.
www.biorxiv.org/content/10.1...
A🧵👇
www.biorxiv.org/content/10.1...
A🧵👇
September 25, 2025 at 6:39 AM
This hypothesis provides a (potential) explanation to many paradoxes and confusions in the field of enhancer-promoter interactions. An absolute must read!!
Reposted by Anton Goloborodko
Scientists are loving our latest study! 🎉
Thrilled that our @elife.bsky.social research article on RAD51 filament strand exchange is August’s most-read in Structural Biology. A landmark for understanding DNA repair. 🧬
Thrilled that our @elife.bsky.social research article on RAD51 filament strand exchange is August’s most-read in Structural Biology. A landmark for understanding DNA repair. 🧬
⛓️ August’s most-read Structural Biology paper is a ‘landmark’ study, describing the structural mechanism of strand exchange by the RAD51 filament: buff.ly/CvSkF34
Have a paper people should see? See what our Editors look for: buff.ly/rr68suW
Have a paper people should see? See what our Editors look for: buff.ly/rr68suW
September 23, 2025 at 9:12 AM
Scientists are loving our latest study! 🎉
Thrilled that our @elife.bsky.social research article on RAD51 filament strand exchange is August’s most-read in Structural Biology. A landmark for understanding DNA repair. 🧬
Thrilled that our @elife.bsky.social research article on RAD51 filament strand exchange is August’s most-read in Structural Biology. A landmark for understanding DNA repair. 🧬