Prahathees Eswara
@eswaralab.bsky.social
Associate Professor at U. South Florida 🌴🌊 | Postdoc - NIH | PhD - U. Houston | Bacterial Cell Biologist 🔬 | he/him
www.eswaralab.com
www.eswaralab.com
Reposted by Prahathees Eswara
Canada Research Chairs www.canada.ca/en/impact-pl...: $1M/year for 8 years, plus up to $6M in CFI infrastructure support. Looking for leading researchers abroad interested in AMR research, antibiotic discovery (Pandemicstopai.ca), phages. Email short vision + CV. Tight deadlines: March 10 & June 15
Canada Impact+ Research Chairs - Canada.ca
www.canada.ca
January 8, 2026 at 7:18 PM
Canada Research Chairs www.canada.ca/en/impact-pl...: $1M/year for 8 years, plus up to $6M in CFI infrastructure support. Looking for leading researchers abroad interested in AMR research, antibiotic discovery (Pandemicstopai.ca), phages. Email short vision + CV. Tight deadlines: March 10 & June 15
Reposted by Prahathees Eswara
We are hiring new faculty!! Come join our amazing community in the Department of Molecular Microbiology at Washington University School of Medicine! The deadline for applications is 2/21, but applications will be reviewed on a rolling basis. facultyopportunities.wustl.edu/Posting/Deta...
Opportunity Details - Faculty Opportunities
facultyopportunities.wustl.edu
January 8, 2026 at 9:05 PM
We are hiring new faculty!! Come join our amazing community in the Department of Molecular Microbiology at Washington University School of Medicine! The deadline for applications is 2/21, but applications will be reviewed on a rolling basis. facultyopportunities.wustl.edu/Posting/Deta...
Reposted by Prahathees Eswara
A new year brings new opportunities: we are looking to fill a permanent professorship position with a Microbiologist preferably with expertise on archaeal biology, RNA biology or imaging techniques to unravel cell biology in prokaryotes! Please share and/or apply :)! www.nature.com/naturecareer...
Professurship (W2) in Microbiology - Regensburg (Stadt), Bayern (DE) job with Universität Regensburg | 12851113
UNIVERSITY OF REGENSBURG The Faculty of Biology and Pre-Clinical Medicine invites applications for a Professurship (W2) in Microbiology To be...
www.nature.com
January 5, 2026 at 9:46 AM
A new year brings new opportunities: we are looking to fill a permanent professorship position with a Microbiologist preferably with expertise on archaeal biology, RNA biology or imaging techniques to unravel cell biology in prokaryotes! Please share and/or apply :)! www.nature.com/naturecareer...
Reposted by Prahathees Eswara
A cool genetic system to study site-pecific replication fork collapse and repair from the brilliant @winterhalterlab.bsky.social
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Rescuing the bacterial replisome at a nick requires recombinational repair and helicase reloading - Nature Communications
DNA damage can lead to cell death. Here, the authors show that a simple cut on either strand of DNA can inactivate bacterial chromosome replication. Surprisingly, only a core set of recombination prot...
www.nature.com
December 30, 2025 at 10:49 AM
A cool genetic system to study site-pecific replication fork collapse and repair from the brilliant @winterhalterlab.bsky.social
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Prahathees Eswara
The sporulation phosphorelay protein Spo0B is membrane localized in Paenibacillus! The transmembrane domain appears to increase interaction with relay partners. Congrats to former lab undergrad @isabellalin.bsky.social and her grad mentor @cassidyprints.bsky.social
journals.asm.org/doi/10.1128/...
journals.asm.org/doi/10.1128/...
journals.asm.org
December 30, 2025 at 1:50 PM
The sporulation phosphorelay protein Spo0B is membrane localized in Paenibacillus! The transmembrane domain appears to increase interaction with relay partners. Congrats to former lab undergrad @isabellalin.bsky.social and her grad mentor @cassidyprints.bsky.social
journals.asm.org/doi/10.1128/...
journals.asm.org/doi/10.1128/...
Reposted by Prahathees Eswara
A major challenge in RNA delivery is overcoming poor loading efficiency into nanoparticles. F. Machinandiarena solves this by using "SSHELs", our particles inspired by bacterial spores, to deliver RNA specifically to HER2+ ovarian cancer cells.
kwnsfk27.r.eu-west-1.awstrack.me/L0/https:%2F...
kwnsfk27.r.eu-west-1.awstrack.me/L0/https:%2F...
kwnsfk27.r.eu-west-1.awstrack.me
December 20, 2025 at 4:11 PM
A major challenge in RNA delivery is overcoming poor loading efficiency into nanoparticles. F. Machinandiarena solves this by using "SSHELs", our particles inspired by bacterial spores, to deliver RNA specifically to HER2+ ovarian cancer cells.
kwnsfk27.r.eu-west-1.awstrack.me/L0/https:%2F...
kwnsfk27.r.eu-west-1.awstrack.me/L0/https:%2F...
Reposted by Prahathees Eswara
Late job posting: My department is hiring a tenure-track faculty member in microbiology! Please share with anyone interested in working at a PUI. We have a preference for someone who can teach Medical Microbiology, but other than that the focus is open-ended. Happy to answer qs.
Microbiologist (AA27034)
All Job Postings will close at 12:01 a.m. CT on the specified Closing Date (if designated). Working Title: Microbiologist (AA27034) Institution: Minnesota State University, Mankato Classification Titl...
minnstate.wd1.myworkdayjobs.com
December 19, 2025 at 9:28 PM
Late job posting: My department is hiring a tenure-track faculty member in microbiology! Please share with anyone interested in working at a PUI. We have a preference for someone who can teach Medical Microbiology, but other than that the focus is open-ended. Happy to answer qs.
Reposted by Prahathees Eswara
Do viruses use RNA to rewire bacteria?
Yes!
In our paper in @cp-molcell.bsky.social RIL-seq reveals interkingdom RNA interactions during λ infection. Phages don’t just encode proteins, they use small RNAs to hijack bacterial replication and fine-tune infection.
#RNA #Phage
doi.org/10.1016/j.mo...
Yes!
In our paper in @cp-molcell.bsky.social RIL-seq reveals interkingdom RNA interactions during λ infection. Phages don’t just encode proteins, they use small RNAs to hijack bacterial replication and fine-tune infection.
#RNA #Phage
doi.org/10.1016/j.mo...
Phage-encoded small RNA hijacks host replication machinery to support the phage lytic cycle
Using RIL-seq, Silverman et al. map the RNA interactome of E. coli during phage lambda
infection and uncover a conserved phage-encoded sRNA that activates host replication
machinery. Their findings re...
www.cell.com
December 19, 2025 at 6:43 AM
Do viruses use RNA to rewire bacteria?
Yes!
In our paper in @cp-molcell.bsky.social RIL-seq reveals interkingdom RNA interactions during λ infection. Phages don’t just encode proteins, they use small RNAs to hijack bacterial replication and fine-tune infection.
#RNA #Phage
doi.org/10.1016/j.mo...
Yes!
In our paper in @cp-molcell.bsky.social RIL-seq reveals interkingdom RNA interactions during λ infection. Phages don’t just encode proteins, they use small RNAs to hijack bacterial replication and fine-tune infection.
#RNA #Phage
doi.org/10.1016/j.mo...
Reposted by Prahathees Eswara
What is better than one? Two connected papers!
#NewResearch
S protein of Streptococcus pneumoniae activates PBP1a and coordinates with a wider GpsB-associated multi-protein complex to regulate peptidoglycan remodelling and cell division.
#MicroSky 🦠
www.nature.com/articles/s41...
#NewResearch
S protein of Streptococcus pneumoniae activates PBP1a and coordinates with a wider GpsB-associated multi-protein complex to regulate peptidoglycan remodelling and cell division.
#MicroSky 🦠
www.nature.com/articles/s41...
December 19, 2025 at 2:06 PM
What is better than one? Two connected papers!
#NewResearch
S protein of Streptococcus pneumoniae activates PBP1a and coordinates with a wider GpsB-associated multi-protein complex to regulate peptidoglycan remodelling and cell division.
#MicroSky 🦠
www.nature.com/articles/s41...
#NewResearch
S protein of Streptococcus pneumoniae activates PBP1a and coordinates with a wider GpsB-associated multi-protein complex to regulate peptidoglycan remodelling and cell division.
#MicroSky 🦠
www.nature.com/articles/s41...
Reposted by Prahathees Eswara
Take advantage of this fantastic opportunity to become part of the SCALE community! Several professorships and group leader positions are available at Goethe University and FIAS. We are looking for professors in the fields of molecular microbiology, cellular biochemistry, and molecular biochemistry.
⏰Call for Applications - Join Our Team and Help Shape Our Cluster
@goetheuni.bsky.social and the Cluster of Excellence SCALE - Subcellular Architecture of Life are seeking 3 highly motivated scientists to join a vibrant and innovative research community on Campus Riedberg.
Share with your network!
@goetheuni.bsky.social and the Cluster of Excellence SCALE - Subcellular Architecture of Life are seeking 3 highly motivated scientists to join a vibrant and innovative research community on Campus Riedberg.
Share with your network!
December 19, 2025 at 10:44 PM
Take advantage of this fantastic opportunity to become part of the SCALE community! Several professorships and group leader positions are available at Goethe University and FIAS. We are looking for professors in the fields of molecular microbiology, cellular biochemistry, and molecular biochemistry.
Reposted by Prahathees Eswara
Can’t wait!! My bacterial cell bio friends, you’re gonna want to go to this GRC and GRS.
Just got word that we are a go for the Bacterial Cell Biology and Development GRS and GRC at Southern New Hampshire University!
GRS will be on June 5-6, 2027
GRC will be from June 6-11, 2027
Block off your calendars Prokaryotic Cell Biologists!
More details to come! Please repost!
GRS will be on June 5-6, 2027
GRC will be from June 6-11, 2027
Block off your calendars Prokaryotic Cell Biologists!
More details to come! Please repost!
December 13, 2025 at 1:44 PM
Can’t wait!! My bacterial cell bio friends, you’re gonna want to go to this GRC and GRS.
Reposted by Prahathees Eswara
Tenure-Track Faculty Position in Microbiology
Come and join great students and colleagues at Hofstra Biology. Please apply using the link below and/or spread the word!
hofstra.peopleadmin.com/postings/6542
Come and join great students and colleagues at Hofstra Biology. Please apply using the link below and/or spread the word!
hofstra.peopleadmin.com/postings/6542
December 12, 2025 at 4:53 PM
Tenure-Track Faculty Position in Microbiology
Come and join great students and colleagues at Hofstra Biology. Please apply using the link below and/or spread the word!
hofstra.peopleadmin.com/postings/6542
Come and join great students and colleagues at Hofstra Biology. Please apply using the link below and/or spread the word!
hofstra.peopleadmin.com/postings/6542
Reposted by Prahathees Eswara
Fer’s tour de force in B. anthracis is out! Fer got Tn-seq running, built an ordered knockout library, defined all essential sporulation genes, and found a peptidoglycan deacetylase inhibitor critical for engulfment. Including our first one-by-all Alphafold screen! journals.plos.org/plosbiology/...
Identification of sporulation genes in Bacillus anthracis highlights similarities and significant differences with Bacillus subtilis
How good is Bacillus subtilis as a model for the spore-forming pathogen Bacillus anthracis? Using high throughput genetics to identify B. anthracis sporulation genes and cytological analysis of the mu...
journals.plos.org
December 13, 2025 at 4:53 PM
Fer’s tour de force in B. anthracis is out! Fer got Tn-seq running, built an ordered knockout library, defined all essential sporulation genes, and found a peptidoglycan deacetylase inhibitor critical for engulfment. Including our first one-by-all Alphafold screen! journals.plos.org/plosbiology/...
Reposted by Prahathees Eswara
🚨The Yap Lab at Northwestern Univ is looking to fill 2 postdoc positions in 2026 to study aspects of Staphylococcus aureus antibiotic resistance and RNA synthesis-degradation. Please contact Frances Yap at frances.yap@northwestern.edu for details. sites.northwestern.edu/yaplab/. Pls repost #Microsky
Homepage | Yap Laboratory
sites.northwestern.edu
December 1, 2025 at 4:45 PM
🚨The Yap Lab at Northwestern Univ is looking to fill 2 postdoc positions in 2026 to study aspects of Staphylococcus aureus antibiotic resistance and RNA synthesis-degradation. Please contact Frances Yap at frances.yap@northwestern.edu for details. sites.northwestern.edu/yaplab/. Pls repost #Microsky
Reposted by Prahathees Eswara
Excited to share my latest postdoctoral work in the Shen Lab at Tufts! In this study, we follow up on an exciting finding by former grad student @shailab.bsky.social that C diff uses its Class A PBP (PBP1) to drive cell division (unlike previously studied bacteria)! journals.plos.org/plosgenetics...
Molecular dissection of Class A PBP function uncovers novel features of the non-canonical Clostridioides difficile divisome complex
Author summary Bacterial cell division is an ancient and essential process, but our molecular understanding of this process is primarily based on studies in a select few model systems. Recent work fou...
journals.plos.org
October 28, 2025 at 1:25 AM
Excited to share my latest postdoctoral work in the Shen Lab at Tufts! In this study, we follow up on an exciting finding by former grad student @shailab.bsky.social that C diff uses its Class A PBP (PBP1) to drive cell division (unlike previously studied bacteria)! journals.plos.org/plosgenetics...
Reposted by Prahathees Eswara
Why does daptomycin resistance appear so fast in Enterococcus? We finally have a clue.
DAP resistance in enterococci pops up quickly. What’s been missing is why resistance-associated membrane changes look the way they do, and why the classic path of mutations is so predictable.
DAP resistance in enterococci pops up quickly. What’s been missing is why resistance-associated membrane changes look the way they do, and why the classic path of mutations is so predictable.
A two-component system signaling hub controls enterococcal membrane remodeling in response to daptomycin https://www.biorxiv.org/content/10.1101/2025.11.16.688641v1
November 17, 2025 at 8:27 PM
Why does daptomycin resistance appear so fast in Enterococcus? We finally have a clue.
DAP resistance in enterococci pops up quickly. What’s been missing is why resistance-associated membrane changes look the way they do, and why the classic path of mutations is so predictable.
DAP resistance in enterococci pops up quickly. What’s been missing is why resistance-associated membrane changes look the way they do, and why the classic path of mutations is so predictable.
🔊 New story!
This GlmR (of hope) article has it all. Cell shape, cytokinesis, c-di-AMP, and catalysis - the famous 4 Cs 💎?
There is also antibiotic resistance, phosphorylation, acetylation, and a (cool) model to explain what shapes Bacillus cells.
Excellent group effort. Congrats team!
#Microsky
This GlmR (of hope) article has it all. Cell shape, cytokinesis, c-di-AMP, and catalysis - the famous 4 Cs 💎?
There is also antibiotic resistance, phosphorylation, acetylation, and a (cool) model to explain what shapes Bacillus cells.
Excellent group effort. Congrats team!
#Microsky
Staying in the loop to make ends meet: roles and regulation of GlmR in Bacillus subtilis https://www.biorxiv.org/content/10.1101/2025.11.05.686802v1
November 6, 2025 at 5:06 AM
🔊 New story!
This GlmR (of hope) article has it all. Cell shape, cytokinesis, c-di-AMP, and catalysis - the famous 4 Cs 💎?
There is also antibiotic resistance, phosphorylation, acetylation, and a (cool) model to explain what shapes Bacillus cells.
Excellent group effort. Congrats team!
#Microsky
This GlmR (of hope) article has it all. Cell shape, cytokinesis, c-di-AMP, and catalysis - the famous 4 Cs 💎?
There is also antibiotic resistance, phosphorylation, acetylation, and a (cool) model to explain what shapes Bacillus cells.
Excellent group effort. Congrats team!
#Microsky
Reposted by Prahathees Eswara
Independent research fellowships leading to tenured positions at the John Innes Centre.
Repost = nice. Thank you very much!!!
Repost = nice. Thank you very much!!!
Shortlisted candidates will be invited to give a seminar at the Fellows Conference, which will be held on 10 March 2026.
Candidates who win Fellowships will be offered a Tenure Track Group Leader position from the outset, initially for 5 years.
Find out more: www.jic.ac.uk/training-car...
Candidates who win Fellowships will be offered a Tenure Track Group Leader position from the outset, initially for 5 years.
Find out more: www.jic.ac.uk/training-car...
October 15, 2025 at 6:32 PM
Reposted by Prahathees Eswara
Job alert ‼️ UChicago Micro is hiring! Open to tenured/tenure track faculty at all levels in any area of microbiology. Come join our amazing and growing department. apply.interfolio.com/174404
October 4, 2025 at 6:44 PM
Job alert ‼️ UChicago Micro is hiring! Open to tenured/tenure track faculty at all levels in any area of microbiology. Come join our amazing and growing department. apply.interfolio.com/174404
Reposted by Prahathees Eswara
Our Department of Microbiology & Immunology at UCSF is running a faculty search this year for a new Assistant Professor! Please see the ad below for details. Searching for a great colleague, mentor, and scientist!
aprecruit.ucsf.edu/JPF05807
aprecruit.ucsf.edu/JPF05807
Microbiology and Immunology – Faculty Position (Ladder Rank) – Assistant Professor
University of California, San Francisco is hiring. Apply now!
aprecruit.ucsf.edu
September 25, 2025 at 5:51 PM
Our Department of Microbiology & Immunology at UCSF is running a faculty search this year for a new Assistant Professor! Please see the ad below for details. Searching for a great colleague, mentor, and scientist!
aprecruit.ucsf.edu/JPF05807
aprecruit.ucsf.edu/JPF05807
Reposted by Prahathees Eswara
cell divisionists & FtsZ fans take note 👇
September 21, 2025 at 12:52 PM
cell divisionists & FtsZ fans take note 👇
Reposted by Prahathees Eswara
We're hiring! 5 tenure track assistant professors. 2 #microbiology, 2 #Evolution, 1 #biologicalclocks
jobs.sciencecareers.org/job/675062/f...
jobs.sciencecareers.org/job/675062/f...
Five Tenure-Track Assistant Professor Positions in Microbiology, Evolution, and Biological Clocks - College Station, Texas job with Department of Biology - TAMU | 675062
Texas A&M University (TAMU) invites applications for five full-time, tenure-track Assistant Professor positions
jobs.sciencecareers.org
September 12, 2025 at 6:11 PM
We're hiring! 5 tenure track assistant professors. 2 #microbiology, 2 #Evolution, 1 #biologicalclocks
jobs.sciencecareers.org/job/675062/f...
jobs.sciencecareers.org/job/675062/f...
Reposted by Prahathees Eswara
Immunization with peptides can elicit antigen-specific T cell responses, but they're not widely used because they are poorly immunogenic and are rapidly cleared. Domenico D'Atri solves this by using our "SSHEL" platform (synthetic bacterial spores) .
journals.asm.org/doi/10.1128/...
journals.asm.org/doi/10.1128/...
Immunization with peptide encapsulated within synthetic spores activates T cell responses and reduces tumor growth | mBio
Effective delivery of antigens to the immune system is essential for activating the
adaptive immune system. Synthetic Spore Husk-Encased Lipids (SSHELs) are synthetic bacterial spore-like particles, w...
journals.asm.org
September 12, 2025 at 2:19 PM
Immunization with peptides can elicit antigen-specific T cell responses, but they're not widely used because they are poorly immunogenic and are rapidly cleared. Domenico D'Atri solves this by using our "SSHEL" platform (synthetic bacterial spores) .
journals.asm.org/doi/10.1128/...
journals.asm.org/doi/10.1128/...
We are hiring! Please share the news.
Tenure Track Assistant Professor in Bacterial Pathogenesis
See link below for details.
We are a vibrantly growing department with friendly colleagues and supportive environment. Bonus: year-round sunshine in Tampa, FL 🌤🌴
Job Ad: tinyurl.com/USF-Microbio...
Tenure Track Assistant Professor in Bacterial Pathogenesis
See link below for details.
We are a vibrantly growing department with friendly colleagues and supportive environment. Bonus: year-round sunshine in Tampa, FL 🌤🌴
Job Ad: tinyurl.com/USF-Microbio...
Assistant Professor - Molecular Biosciences
Department Name / Number: Molecular Biosciences / 0-1210-000 College: College of Arts and Sciences Hiring Salary: Negotiable Appointment Start Date: August 7, 2026 The Department of Molecular Bioscien...
tinyurl.com
September 12, 2025 at 1:53 PM
We are hiring! Please share the news.
Tenure Track Assistant Professor in Bacterial Pathogenesis
See link below for details.
We are a vibrantly growing department with friendly colleagues and supportive environment. Bonus: year-round sunshine in Tampa, FL 🌤🌴
Job Ad: tinyurl.com/USF-Microbio...
Tenure Track Assistant Professor in Bacterial Pathogenesis
See link below for details.
We are a vibrantly growing department with friendly colleagues and supportive environment. Bonus: year-round sunshine in Tampa, FL 🌤🌴
Job Ad: tinyurl.com/USF-Microbio...
Reposted by Prahathees Eswara
So great to see Lucy Shapiro — a scientific hero of mine both for her pioneering work and for her incredible communication skills —honored today www.nytimes.com/2025/09/11/h...
Major Medical Prizes Given to Cell Biology and Cystic Fibrosis Pioneers
www.nytimes.com
September 11, 2025 at 10:34 PM
So great to see Lucy Shapiro — a scientific hero of mine both for her pioneering work and for her incredible communication skills —honored today www.nytimes.com/2025/09/11/h...