Yves Brun lab
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brunlabcaulo.bsky.social
Yves Brun lab
@brunlabcaulo.bsky.social
We like to look at bacteria do the things they do. Université de Montréal.
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We just launched the web site for our consortium to accelerate antibiotic discovery by combining high throughput, high content approaches and AI, PandemicStop-AI. Check it out: pandemicstopai.ca
Reposted by Yves Brun lab
We just launched the web site for our consortium to accelerate antibiotic discovery by combining high throughput, high content approaches and AI, PandemicStop-AI. Check it out: pandemicstopai.ca
December 22, 2025 at 8:13 PM
We just launched the web site for our consortium to accelerate antibiotic discovery by combining high throughput, high content approaches and AI, PandemicStop-AI. Check it out: pandemicstopai.ca
December 22, 2025 at 8:13 PM
Reposted by Yves Brun lab
We are looking forward to sunnier days and some fantastic presentations at our #ProkaryoticCellBio meeting in Portugal next July! Grants, Early Bird pricing and Talk slots close on 12 Jan, register & submit today to join us! 🌞
👉https://bit.ly/48G29dP
December 16, 2025 at 3:36 PM
December 14, 2025 at 9:56 PM
A study in contrast this morning. Frost, smog, and beach.
December 9, 2025 at 2:15 PM
Wow, really cool work! Congratulations!
Hot off the press! Our latest paper led by @fernpizza.bsky.social, understanding how plasmids evolve inside cells. These small, self-replicating DNA circles live inside bacteria and carry antibiotic resistance genes, but also compete with one another to replicate. 1/
www.science.org/doi/10.1126/...
Intracellular competition shapes plasmid population dynamics
From populations of multicellular organisms to selfish genetic elements, conflicts between levels of biological organization are central to evolution. Plasmids are extrachromosomal, self-replicating g...
www.science.org
November 20, 2025 at 11:57 PM
Not funny!
November 11, 2025 at 11:42 AM
As mentioned, here is the preprint by Jensen and @viollierpat.bsky.social on the in situ structure of the Tad pilus. www.biorxiv.org/content/10.1.... Nice work and great to see that we are seeing the same thing! Our preprint: www.biorxiv.org/content/10.1... #microsky
Great collaboration with @guo-lab.bsky.social to determine an in situ architectural model of the Tad pilus machine. Be on the lookout soon for a preprint on the same topic by Grant Jensen and @viollierpat.bsky.social. #microsky
November 8, 2025 at 7:35 PM
Reposted by Yves Brun lab
Great collaboration with @brunlabcaulo.bsky.social for resolving the Tad pilus machine structure by cryo-ET. Beautiful work by graduate students James Iarocci and Ryu Williston in our lab.

Preprint:https://www.biorxiv.org/content/10.1101/2025.11.05.686773v1
November 6, 2025 at 3:58 PM
More useful with the link #microsky www.biorxiv.org/content/10.1...
November 6, 2025 at 3:57 PM
Great collaboration with @guo-lab.bsky.social to determine an in situ architectural model of the Tad pilus machine. Be on the lookout soon for a preprint on the same topic by Grant Jensen and @viollierpat.bsky.social. #microsky
November 6, 2025 at 3:51 PM
Forgot to post the recently published version of this paper on the role of a minor pilin-like protein in surface sensing journals.asm.org/doi/10.1128/...
October 31, 2025 at 6:54 PM
Light reading to distract me from the news. Yet it is strangely familiar.
September 19, 2025 at 1:38 AM
Why do we always submit grant proposals at the last minute? This never ceases to amaze me.
July 15, 2025 at 2:00 AM
July 9, 2025 at 10:12 PM
Please repost: PhD position with my lab and @weisslab.bsky.social in a great collaboration on bacterial adhesion #microsky. See drive.google.com/file/d/1GJD4...
July 9, 2025 at 5:56 PM
As I was saying, happy to be back home! Cheers!
July 5, 2025 at 12:34 AM
Congratulations Marie! Immensely proud! Looking forward to seeing where you take your project on evolution of bacterial elongation.
Excited to share that I have been appointed F.R.S.-FNRS Research Associate to launch my independent research group at the University of Namur!
We will study the diversity, regulation & environmental control of bacterial cell elongation.
More soon- new projects, collaborations & opportunities ahead!
July 4, 2025 at 9:01 PM
Sabbatical is over! I really enjoyed my time in Marseille for 10 months @lcbofficiel.bsky.social but very happy to be back in Montreal and with my lab. Also, the view from my office 😀
July 4, 2025 at 5:39 PM
Excited to see our automated HT growth/microscopy screening platform coming together. Pictured: the intermediate version to screen 5-10,000/day unattended. Diagrammed is the full platform due next summer after renovations @ 20,000/day and integrated with our colony picker.
July 4, 2025 at 5:22 PM
Reposted by Yves Brun lab
Exciting news!
My work with Liu Yang in the @brunlabcaulo.bsky.social, “Phenotypic plasticity in cell elongation among closely related bacterial species”, has been selected as an Editors’ Highlight in @natcomms.nature.com under Microbiology and infectious diseases!

Check it out here:
Editors' Highlights | Nature Communications
Editors' Highlights
www.nature.com
June 18, 2025 at 2:04 AM
How does your favorite species elongate? 🧵 "Phenotypic plasticity in bacterial elongation among closely related species". Happy to see this paper in print @natcomms.nature.com. Nice work by @mariedelaby.bsky.social, Liu Yang et al. See original 🧵, different colours, same data and conclusions.
June 2, 2025 at 3:54 PM
Excited to be in Grenoble surrounded by mountains to give a seminar today at the IBS where I was on sabbatical 10 years ago.
May 16, 2025 at 5:38 AM
Reposted by Yves Brun lab
I got hit by some rather sudden and extreme financial hardship so if anyone is in need of remote wetlab contract research, strictly BSL1, do let me know. Currently scrambling for gigs.

Plant, Bacterial, Archaeal Non-model Bioeng
Custom Lab Hardware
Turn Key Genetic Design

Please repost for reach 💚
May 2, 2025 at 2:39 PM
April 27, 2025 at 5:29 PM