Greg Harrison
@bactophile.bsky.social
Postdoc at Tufts University
Studying C. difficile 🔬
Chicago > St. Louis > Boston
👨🔬🪴📚🍷🏳️🌈
Studying C. difficile 🔬
Chicago > St. Louis > Boston
👨🔬🪴📚🍷🏳️🌈
Reposted by Greg Harrison
The 5th of 6 faculty positions in UNC Biology is posted. We're working with the @ncbg.bsky.social to fill a joint position as Director of the UNC Herbarium at @ncbg.bsky.social and as Associate Professor within the Department of Biology (BIOL). Please share 1/n
unc.peopleadmin.com/postings/308...
unc.peopleadmin.com/postings/308...
Associate Professor & Director of NCBG Herbarium
This is a research, teaching, and public service position at the University of North Carolina at Chapel Hill, serving jointly as Herbarium Director at the North Carolina Botanical Garden (NCBG) and as...
unc.peopleadmin.com
November 6, 2025 at 11:36 AM
The 5th of 6 faculty positions in UNC Biology is posted. We're working with the @ncbg.bsky.social to fill a joint position as Director of the UNC Herbarium at @ncbg.bsky.social and as Associate Professor within the Department of Biology (BIOL). Please share 1/n
unc.peopleadmin.com/postings/308...
unc.peopleadmin.com/postings/308...
Excited to share my latest postdoctoral work in the Shen Lab at Tufts! In this study, we follow up on an exciting finding by former grad student @shailab.bsky.social that C diff uses its Class A PBP (PBP1) to drive cell division (unlike previously studied bacteria)! journals.plos.org/plosgenetics...
Molecular dissection of Class A PBP function uncovers novel features of the non-canonical Clostridioides difficile divisome complex
Author summary Bacterial cell division is an ancient and essential process, but our molecular understanding of this process is primarily based on studies in a select few model systems. Recent work fou...
journals.plos.org
October 28, 2025 at 1:25 AM
Excited to share my latest postdoctoral work in the Shen Lab at Tufts! In this study, we follow up on an exciting finding by former grad student @shailab.bsky.social that C diff uses its Class A PBP (PBP1) to drive cell division (unlike previously studied bacteria)! journals.plos.org/plosgenetics...
Reposted by Greg Harrison
Friendly reminder: 🎉 Pre-register today & get ready to join our FREE online celebration. Everyone is welcome. To keep #BlackInMicro alive Donate: tinyurl.com/GiveBiM and Register to attend: linktr.ee/BlackInMicro (see links in bio) #BiMWeek2025
October 3, 2025 at 8:40 PM
Friendly reminder: 🎉 Pre-register today & get ready to join our FREE online celebration. Everyone is welcome. To keep #BlackInMicro alive Donate: tinyurl.com/GiveBiM and Register to attend: linktr.ee/BlackInMicro (see links in bio) #BiMWeek2025
Reposted by Greg Harrison
UChicago Microbiology is searching for tenured or tenure-track faculty working in host-pathogens interactions, viral and bacterial pathogenesis, and emerging infectious diseases. Come join our vibrant Department! microbiology.uchicago.edu
Apply here apply.interfolio.com/174404
Apply here apply.interfolio.com/174404
Apply - Interfolio
{{$ctrl.$state.data.pageTitle}} - Apply - Interfolio
apply.interfolio.com
October 5, 2025 at 12:03 PM
UChicago Microbiology is searching for tenured or tenure-track faculty working in host-pathogens interactions, viral and bacterial pathogenesis, and emerging infectious diseases. Come join our vibrant Department! microbiology.uchicago.edu
Apply here apply.interfolio.com/174404
Apply here apply.interfolio.com/174404
Reposted by Greg Harrison
🚨 Microbiologists! We are recruiting Assistant / Associate Professors in 3 collaborative areas of our U. Pittsburgh School of Medicine.
1) MMG (my dept): fundamental research in med micro
2) Peds ID / I4Kids institute
3) Center for Vaccine Research
🔗 to all 3 w/info: www.linkedin.com/posts/vaughn...
1) MMG (my dept): fundamental research in med micro
2) Peds ID / I4Kids institute
3) Center for Vaccine Research
🔗 to all 3 w/info: www.linkedin.com/posts/vaughn...
Faculty Professor Associate - Full-Time | Vaughn Cooper
We are recruiting Faculty microbiologists in three (3) different, complementary, and collaborative areas at the University of Pittsburgh associated with the School of Medicine.
1) Fundamental researc...
www.linkedin.com
September 23, 2025 at 10:31 PM
🚨 Microbiologists! We are recruiting Assistant / Associate Professors in 3 collaborative areas of our U. Pittsburgh School of Medicine.
1) MMG (my dept): fundamental research in med micro
2) Peds ID / I4Kids institute
3) Center for Vaccine Research
🔗 to all 3 w/info: www.linkedin.com/posts/vaughn...
1) MMG (my dept): fundamental research in med micro
2) Peds ID / I4Kids institute
3) Center for Vaccine Research
🔗 to all 3 w/info: www.linkedin.com/posts/vaughn...
Fantastic meeting! Heard about SO MUCH groundbreaking work and met so many incredible people! Such a great community 😃
And that’s a wrap on the Great Wall Symposium 2025!
Roll on 2027, venue to be confirmed shortly …
Roll on 2027, venue to be confirmed shortly …
September 18, 2025 at 7:15 PM
Fantastic meeting! Heard about SO MUCH groundbreaking work and met so many incredible people! Such a great community 😃
Reposted by Greg Harrison
Rich Losick’s Farewell Publication Reexamines a Molecular Biology Milestone 🧪 🧬 #AcademicSky #higherEd
www.mcb.harvard.edu/department/n... @cryptogenomicon.bsky.social @craigphunter.bsky.social @rachellegaudet.bsky.social @harvardmagazine.bsky.social @naoshigeuchida.bsky.social
www.mcb.harvard.edu/department/n... @cryptogenomicon.bsky.social @craigphunter.bsky.social @rachellegaudet.bsky.social @harvardmagazine.bsky.social @naoshigeuchida.bsky.social
Rich Losick’s Farewell Publication Reexamines a Molecular Biology Milestone - Harvard University - Department of Molecular & Cellular Biology
Richard Losick, Maria Moors Cabot Professor of Biology, Emeritus in Harvard’s Department of Molecular and Cellular Biology, is about to publish what he describes as his “last paper”—though […]
www.mcb.harvard.edu
September 11, 2025 at 8:01 PM
Rich Losick’s Farewell Publication Reexamines a Molecular Biology Milestone 🧪 🧬 #AcademicSky #higherEd
www.mcb.harvard.edu/department/n... @cryptogenomicon.bsky.social @craigphunter.bsky.social @rachellegaudet.bsky.social @harvardmagazine.bsky.social @naoshigeuchida.bsky.social
www.mcb.harvard.edu/department/n... @cryptogenomicon.bsky.social @craigphunter.bsky.social @rachellegaudet.bsky.social @harvardmagazine.bsky.social @naoshigeuchida.bsky.social
Reposted by Greg Harrison
Analysis of essential genes in Clostridioides difficile by CRISPRi and Tn-seq | Journal of Bacteriology journals.asm.org/doi/10.1128/...
Analysis of essential genes in Clostridioides difficile by CRISPRi and Tn-seq | Journal of Bacteriology
Clostridioides difficile is an opportunistic pathogen for which better antibiotics are sorely needed. Most
antibiotics target pathways that are essential for viability. Here, we use saturation
transpo...
journals.asm.org
September 12, 2025 at 12:12 PM
Analysis of essential genes in Clostridioides difficile by CRISPRi and Tn-seq | Journal of Bacteriology journals.asm.org/doi/10.1128/...
Reposted by Greg Harrison
NEW: Don't ask too many questions, but...
NIH may not re-terminate the 900ish grants at issue in the main NIH lawsuits after all.
To the PIs of reinstated grants, SPEND NOW!
🧵 Here's what NIH is probably thinking. Bear with me:
NIH may not re-terminate the 900ish grants at issue in the main NIH lawsuits after all.
To the PIs of reinstated grants, SPEND NOW!
🧵 Here's what NIH is probably thinking. Bear with me:
August 29, 2025 at 2:50 PM
NEW: Don't ask too many questions, but...
NIH may not re-terminate the 900ish grants at issue in the main NIH lawsuits after all.
To the PIs of reinstated grants, SPEND NOW!
🧵 Here's what NIH is probably thinking. Bear with me:
NIH may not re-terminate the 900ish grants at issue in the main NIH lawsuits after all.
To the PIs of reinstated grants, SPEND NOW!
🧵 Here's what NIH is probably thinking. Bear with me:
Reposted by Greg Harrison
Here we show that >90% of Paenibacillus encode a unique Spo0B with a transmembrane domain! TM domain helps it interact with its phosphorelay partners. Congrats to @isabellalin.bsky.social who left for grad school this week and her mentor @cassidyprints.bsky.social! www.biorxiv.org/content/10.1...
Conservation of sporulation genes and a transmembrane-containing Spo0B variant in Paenibacillus
Sporulation is a strategy employed by many bacteria to survive harsh environmental conditions. The genus Paenibacillus includes spore-forming species notorious for spoiling pasteurized dairy products ...
www.biorxiv.org
August 28, 2025 at 11:27 PM
Here we show that >90% of Paenibacillus encode a unique Spo0B with a transmembrane domain! TM domain helps it interact with its phosphorelay partners. Congrats to @isabellalin.bsky.social who left for grad school this week and her mentor @cassidyprints.bsky.social! www.biorxiv.org/content/10.1...
Reposted by Greg Harrison
Post a non-religious photo you think of as holy.
August 20, 2025 at 7:54 PM
Post a non-religious photo you think of as holy.
Reposted by Greg Harrison
New preprint from us! The latest part of our C. difficile vancomycin resistance story. We identified a new two-component system (VnrRS) that can control expression of the vanG pathway - just needs one amino acid change
@buddlejess.bsky.social @brockhurstlab.bsky.social @claireyt.bsky.social
@buddlejess.bsky.social @brockhurstlab.bsky.social @claireyt.bsky.social
A novel two-component system controls vancomycin resistance in epidemic Clostridioides difficile
The glycopeptide antibiotic vancomycin is the frontline treatment for C. difficile infection in the UK. There have been only sporadic reports of resistance in the clinic but testing is rare so the tru...
www.biorxiv.org
August 22, 2025 at 9:39 AM
New preprint from us! The latest part of our C. difficile vancomycin resistance story. We identified a new two-component system (VnrRS) that can control expression of the vanG pathway - just needs one amino acid change
@buddlejess.bsky.social @brockhurstlab.bsky.social @claireyt.bsky.social
@buddlejess.bsky.social @brockhurstlab.bsky.social @claireyt.bsky.social
😔
5-4 Supreme Court rules that NIH can terminate grants pending the full ruling.
thehill.com/regulation/c...
I have no (printable) words...
thehill.com/regulation/c...
I have no (printable) words...
a close up of a white dog 's face with red eyes
ALT: a close up of a white dog 's face with red eyes
media.tenor.com
August 21, 2025 at 11:39 PM
😔
Reposted by Greg Harrison
We are hiring! The Dept of Microbiology and Molecular Genetics is looking for faculty at the Assistant or Associate professor level (tenure track). Please consider joining our vibrant microbiology and immunology community at the University of Pittsburgh School of medicine
August 20, 2025 at 7:41 PM
We are hiring! The Dept of Microbiology and Molecular Genetics is looking for faculty at the Assistant or Associate professor level (tenure track). Please consider joining our vibrant microbiology and immunology community at the University of Pittsburgh School of medicine
Reposted by Greg Harrison
Elio Schaechter was one of my heroes. His 1958 paper with Ole Maaløe and Niels Kjeldgaard (fondly known as “SMK”) is a North Star for so much work in my group. A wonderful scientist, great communicator, and a very kind person. May his memory be a blessing.
August 15, 2025 at 3:40 PM
Elio Schaechter was one of my heroes. His 1958 paper with Ole Maaløe and Niels Kjeldgaard (fondly known as “SMK”) is a North Star for so much work in my group. A wonderful scientist, great communicator, and a very kind person. May his memory be a blessing.
Reposted by Greg Harrison
On Aug. 1, ASM & partner societies filed an expanded amicus brief with SCOTUS to defend scientific integrity & protect early-career researchers. The brief highlights the harm caused by NIH grant terminations, including canceling the MOSAIC program. asm.org/press-releas...
Scientific Societies File Supreme Court Amicus Brief in Support of NIH Grantees
ASM and fellow societies filed an amicus brief with the Supreme Court, calling for the swift restoration of NIH grant funding supporting early-career scientists, such as the MOSAIC program.
asm.org
August 4, 2025 at 9:23 PM
On Aug. 1, ASM & partner societies filed an expanded amicus brief with SCOTUS to defend scientific integrity & protect early-career researchers. The brief highlights the harm caused by NIH grant terminations, including canceling the MOSAIC program. asm.org/press-releas...
Reposted by Greg Harrison
The CspC:CspA heterodimer transduces germinant and co-germinant signals during Clostridioides difficile spore germination. https://www.biorxiv.org/content/10.1101/2025.08.01.668244v1
August 3, 2025 at 3:16 AM
The CspC:CspA heterodimer transduces germinant and co-germinant signals during Clostridioides difficile spore germination. https://www.biorxiv.org/content/10.1101/2025.08.01.668244v1
Reposted by Greg Harrison
Excited to share this collaborative study with @ritatamayo.bsky.social showing that E. faecalis influences C. diff morphology through the phase variable CmrRST system! This work was co-led by the amazing team of @ashleyweiss.bsky.social and Jilarie Santos-Santiago!
Enterococcus faecalis modulates phase variation in Clostridioides difficile https://www.biorxiv.org/content/10.1101/2025.07.24.666506v1
July 26, 2025 at 3:08 AM
Excited to share this collaborative study with @ritatamayo.bsky.social showing that E. faecalis influences C. diff morphology through the phase variable CmrRST system! This work was co-led by the amazing team of @ashleyweiss.bsky.social and Jilarie Santos-Santiago!
Reposted by Greg Harrison
Excited to post our first S. aureus preprint on biorxiv! Big congrats to co-first authors, postdocs @anjali20anil.bsky.social and Rezia Braza, and really enjoyed the collaboration with @torreslab.bsky.social !
Staphylococcus aureus exhibits spatiotemporal heterogeneity in Sae activity during kidney abscess development https://www.biorxiv.org/content/10.1101/2025.07.08.663646v1
July 10, 2025 at 1:17 AM
Excited to post our first S. aureus preprint on biorxiv! Big congrats to co-first authors, postdocs @anjali20anil.bsky.social and Rezia Braza, and really enjoyed the collaboration with @torreslab.bsky.social !
Reposted by Greg Harrison
NIH employees issued a declaration on June 9 highlighting the need for resources that NIH uses to protect the public, innovate science and research important health issues Americans are facing. Read the declaration and consider signing the support letter: www.standupforscience.net/bethesda-dec...
NIH Open Letter of Support — STAND UP FOR SCIENCE
Add your name now!
www.standupforscience.net
June 13, 2025 at 12:48 PM
NIH employees issued a declaration on June 9 highlighting the need for resources that NIH uses to protect the public, innovate science and research important health issues Americans are facing. Read the declaration and consider signing the support letter: www.standupforscience.net/bethesda-dec...
Reposted by Greg Harrison
Joint effort from lab alumnus Dr. Sarah Anderson and her fantastic undergraduate Isabella Mack on #ppGpp mediated control of cell wall synthesis in E. coli and the consequences for #AMR now up on @biorxiv-microbiol.bsky.social
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Enzymatic Activity of PBP1B Compensates for β-lactam Mediated Inhibition of PBP2 in Cells Overproducing ppGpp
The alarmone (p)ppGpp (ppGpp) accumulates in response to starvation and other stress, leading to inhibition of multiple biosynthetic pathways and, at high concentrations, suppression of bacterial grow...
www.biorxiv.org
June 13, 2025 at 11:47 AM
Joint effort from lab alumnus Dr. Sarah Anderson and her fantastic undergraduate Isabella Mack on #ppGpp mediated control of cell wall synthesis in E. coli and the consequences for #AMR now up on @biorxiv-microbiol.bsky.social
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Greg Harrison
This is shameful
If you weren't angry enough already, here are the rates of non-competitive renewals through May.
4008 Non-competitive renewals were due to be funded in May.
The total funded was 99!
Some is due to terminations, but most is due to slow grant making due to DOGE review and other impediments.
1/2
4008 Non-competitive renewals were due to be funded in May.
The total funded was 99!
Some is due to terminations, but most is due to slow grant making due to DOGE review and other impediments.
1/2
June 11, 2025 at 7:14 PM
This is shameful
Reposted by Greg Harrison
Join the 22,339 people who have joined to support our NIH colleagues. Let's get this to 50,000 RT
The new leadership of NIH is dismantling long standing biomedical science programs & putting in their place scientifically questionable ideas. A courageous group of current NIH employees pushed back, publishing “The Bethesda Declaration” 1/2
www.standupforscience.net/bethesda-dec...
www.standupforscience.net/bethesda-dec...
Bethesda Declaration — STAND UP FOR SCIENCE
Support NIH Staff Now!
www.standupforscience.net
June 12, 2025 at 4:16 PM
Join the 22,339 people who have joined to support our NIH colleagues. Let's get this to 50,000 RT
Reposted by Greg Harrison
What does 18,000+ brave signatories look like standing together in massive solidarity with the #NIH heroes of the historic Bethesda Declaration??...
Find out by adding YOUR NAME to our #NIHLove letter here! -
actionnetwork.org/forms/add-na...
#StandUpForScience
#BethesdaDeclaration
#StopTrump
Find out by adding YOUR NAME to our #NIHLove letter here! -
actionnetwork.org/forms/add-na...
#StandUpForScience
#BethesdaDeclaration
#StopTrump
ADD YOUR NAME: Sign the Open Letter in Support of NIH Staff
Join the courageous and committed National Institutes of Health (NIH) public servants by adding your name now.
actionnetwork.org
June 11, 2025 at 11:10 AM
What does 18,000+ brave signatories look like standing together in massive solidarity with the #NIH heroes of the historic Bethesda Declaration??...
Find out by adding YOUR NAME to our #NIHLove letter here! -
actionnetwork.org/forms/add-na...
#StandUpForScience
#BethesdaDeclaration
#StopTrump
Find out by adding YOUR NAME to our #NIHLove letter here! -
actionnetwork.org/forms/add-na...
#StandUpForScience
#BethesdaDeclaration
#StopTrump