Greg Harrison
@bactophile.bsky.social
Postdoc at Tufts University
Studying C. difficile 🔬
Chicago > St. Louis > Boston
👨🔬🪴📚🍷🏳️🌈
Studying C. difficile 🔬
Chicago > St. Louis > Boston
👨🔬🪴📚🍷🏳️🌈
Reposted by Greg Harrison
And check out the accompanying paper from the Grangeasse lab: www.nature.com/articles/s41...
Streptococcus pneumoniae S protein activates PBP1a to regulate peptidoglycan remodelling and cell division - Nature Microbiology
S protein interacts with and activates PBP1a during cell division, as part of a larger GpsB-associated multiprotein complex that coordinates peptidoglycan remodelling in Streptococcus pneumoniae.
www.nature.com
December 19, 2025 at 10:31 AM
And check out the accompanying paper from the Grangeasse lab: www.nature.com/articles/s41...
Reposted by Greg Harrison
December 19, 2025 at 10:31 AM
Reposted by Greg Harrison
Calling all postdoctoral women scientists in microbiology! We're here to support you; receive up to $2,000 to travel to a meeting, visit another laboratory or take a course to enhance your research skills. Check eligibility and apply now: asm.social/2Jh
December 10, 2025 at 7:01 PM
Calling all postdoctoral women scientists in microbiology! We're here to support you; receive up to $2,000 to travel to a meeting, visit another laboratory or take a course to enhance your research skills. Check eligibility and apply now: asm.social/2Jh
Reposted by Greg Harrison
indeed, 𝘙𝘶𝘨𝘰𝘴𝘪𝘵𝘢𝘭𝘦𝘢 𝘰𝘳𝘺𝘻𝘢𝘦 looke like fusilli, which are notably better at holding on salsa di pomodoro than spaghetti... and as pasta addicts, we fell instantly in love with the shape of this newly described alphaproteo from the Rhizobiales 🤭
#MicroSky
#MicroSky
December 10, 2025 at 7:52 PM
indeed, 𝘙𝘶𝘨𝘰𝘴𝘪𝘵𝘢𝘭𝘦𝘢 𝘰𝘳𝘺𝘻𝘢𝘦 looke like fusilli, which are notably better at holding on salsa di pomodoro than spaghetti... and as pasta addicts, we fell instantly in love with the shape of this newly described alphaproteo from the Rhizobiales 🤭
#MicroSky
#MicroSky
Reposted by Greg Harrison
There's just over 2 weeks left to apply for a fully funded PhD studentship with us working on C. difficile vancomycin resistance. Two more studentships - linked in the thread below - close in early January
November 19, 2025 at 1:45 PM
There's just over 2 weeks left to apply for a fully funded PhD studentship with us working on C. difficile vancomycin resistance. Two more studentships - linked in the thread below - close in early January
Reposted by Greg Harrison
Three German universities offering post-docs for researchers "who cannot conduct or continue their work in the USA appropriately because of actual political pressure. "
www.uni-konstanz.de/zukunftskoll...
www.uni-konstanz.de/zukunftskoll...
Early Career Rescue Fellowship
www.uni-konstanz.de
November 11, 2025 at 7:10 PM
Three German universities offering post-docs for researchers "who cannot conduct or continue their work in the USA appropriately because of actual political pressure. "
www.uni-konstanz.de/zukunftskoll...
www.uni-konstanz.de/zukunftskoll...
Reposted by Greg Harrison
The 5th of 6 faculty positions in UNC Biology is posted. We're working with the @ncbg.bsky.social to fill a joint position as Director of the UNC Herbarium at @ncbg.bsky.social and as Associate Professor within the Department of Biology (BIOL). Please share 1/n
unc.peopleadmin.com/postings/308...
unc.peopleadmin.com/postings/308...
Associate Professor & Director of NCBG Herbarium
This is a research, teaching, and public service position at the University of North Carolina at Chapel Hill, serving jointly as Herbarium Director at the North Carolina Botanical Garden (NCBG) and as...
unc.peopleadmin.com
November 6, 2025 at 11:36 AM
The 5th of 6 faculty positions in UNC Biology is posted. We're working with the @ncbg.bsky.social to fill a joint position as Director of the UNC Herbarium at @ncbg.bsky.social and as Associate Professor within the Department of Biology (BIOL). Please share 1/n
unc.peopleadmin.com/postings/308...
unc.peopleadmin.com/postings/308...
Excited to share my latest postdoctoral work in the Shen Lab at Tufts! In this study, we follow up on an exciting finding by former grad student @shailab.bsky.social that C diff uses its Class A PBP (PBP1) to drive cell division (unlike previously studied bacteria)! journals.plos.org/plosgenetics...
Molecular dissection of Class A PBP function uncovers novel features of the non-canonical Clostridioides difficile divisome complex
Author summary Bacterial cell division is an ancient and essential process, but our molecular understanding of this process is primarily based on studies in a select few model systems. Recent work fou...
journals.plos.org
October 28, 2025 at 1:25 AM
Excited to share my latest postdoctoral work in the Shen Lab at Tufts! In this study, we follow up on an exciting finding by former grad student @shailab.bsky.social that C diff uses its Class A PBP (PBP1) to drive cell division (unlike previously studied bacteria)! journals.plos.org/plosgenetics...
Reposted by Greg Harrison
Friendly reminder: 🎉 Pre-register today & get ready to join our FREE online celebration. Everyone is welcome. To keep #BlackInMicro alive Donate: tinyurl.com/GiveBiM and Register to attend: linktr.ee/BlackInMicro (see links in bio) #BiMWeek2025
October 3, 2025 at 8:40 PM
Friendly reminder: 🎉 Pre-register today & get ready to join our FREE online celebration. Everyone is welcome. To keep #BlackInMicro alive Donate: tinyurl.com/GiveBiM and Register to attend: linktr.ee/BlackInMicro (see links in bio) #BiMWeek2025
Reposted by Greg Harrison
UChicago Microbiology is searching for tenured or tenure-track faculty working in host-pathogens interactions, viral and bacterial pathogenesis, and emerging infectious diseases. Come join our vibrant Department! microbiology.uchicago.edu
Apply here apply.interfolio.com/174404
Apply here apply.interfolio.com/174404
Apply - Interfolio
{{$ctrl.$state.data.pageTitle}} - Apply - Interfolio
apply.interfolio.com
October 5, 2025 at 12:03 PM
UChicago Microbiology is searching for tenured or tenure-track faculty working in host-pathogens interactions, viral and bacterial pathogenesis, and emerging infectious diseases. Come join our vibrant Department! microbiology.uchicago.edu
Apply here apply.interfolio.com/174404
Apply here apply.interfolio.com/174404
Reposted by Greg Harrison
🚨 Microbiologists! We are recruiting Assistant / Associate Professors in 3 collaborative areas of our U. Pittsburgh School of Medicine.
1) MMG (my dept): fundamental research in med micro
2) Peds ID / I4Kids institute
3) Center for Vaccine Research
🔗 to all 3 w/info: www.linkedin.com/posts/vaughn...
1) MMG (my dept): fundamental research in med micro
2) Peds ID / I4Kids institute
3) Center for Vaccine Research
🔗 to all 3 w/info: www.linkedin.com/posts/vaughn...
Faculty Professor Associate - Full-Time | Vaughn Cooper
We are recruiting Faculty microbiologists in three (3) different, complementary, and collaborative areas at the University of Pittsburgh associated with the School of Medicine.
1) Fundamental researc...
www.linkedin.com
September 23, 2025 at 10:31 PM
🚨 Microbiologists! We are recruiting Assistant / Associate Professors in 3 collaborative areas of our U. Pittsburgh School of Medicine.
1) MMG (my dept): fundamental research in med micro
2) Peds ID / I4Kids institute
3) Center for Vaccine Research
🔗 to all 3 w/info: www.linkedin.com/posts/vaughn...
1) MMG (my dept): fundamental research in med micro
2) Peds ID / I4Kids institute
3) Center for Vaccine Research
🔗 to all 3 w/info: www.linkedin.com/posts/vaughn...
Fantastic meeting! Heard about SO MUCH groundbreaking work and met so many incredible people! Such a great community 😃
And that’s a wrap on the Great Wall Symposium 2025!
Roll on 2027, venue to be confirmed shortly …
Roll on 2027, venue to be confirmed shortly …
September 18, 2025 at 7:15 PM
Fantastic meeting! Heard about SO MUCH groundbreaking work and met so many incredible people! Such a great community 😃
Reposted by Greg Harrison
Rich Losick’s Farewell Publication Reexamines a Molecular Biology Milestone 🧪 🧬 #AcademicSky #higherEd
www.mcb.harvard.edu/department/n... @cryptogenomicon.bsky.social @craigphunter.bsky.social @rachellegaudet.bsky.social @harvardmagazine.bsky.social @naoshigeuchida.bsky.social
www.mcb.harvard.edu/department/n... @cryptogenomicon.bsky.social @craigphunter.bsky.social @rachellegaudet.bsky.social @harvardmagazine.bsky.social @naoshigeuchida.bsky.social
Rich Losick’s Farewell Publication Reexamines a Molecular Biology Milestone - Harvard University - Department of Molecular & Cellular Biology
Richard Losick, Maria Moors Cabot Professor of Biology, Emeritus in Harvard’s Department of Molecular and Cellular Biology, is about to publish what he describes as his “last paper”—though […]
www.mcb.harvard.edu
September 11, 2025 at 8:01 PM
Rich Losick’s Farewell Publication Reexamines a Molecular Biology Milestone 🧪 🧬 #AcademicSky #higherEd
www.mcb.harvard.edu/department/n... @cryptogenomicon.bsky.social @craigphunter.bsky.social @rachellegaudet.bsky.social @harvardmagazine.bsky.social @naoshigeuchida.bsky.social
www.mcb.harvard.edu/department/n... @cryptogenomicon.bsky.social @craigphunter.bsky.social @rachellegaudet.bsky.social @harvardmagazine.bsky.social @naoshigeuchida.bsky.social
Reposted by Greg Harrison
Analysis of essential genes in Clostridioides difficile by CRISPRi and Tn-seq | Journal of Bacteriology journals.asm.org/doi/10.1128/...
Analysis of essential genes in Clostridioides difficile by CRISPRi and Tn-seq | Journal of Bacteriology
Clostridioides difficile is an opportunistic pathogen for which better antibiotics are sorely needed. Most
antibiotics target pathways that are essential for viability. Here, we use saturation
transpo...
journals.asm.org
September 12, 2025 at 12:12 PM
Analysis of essential genes in Clostridioides difficile by CRISPRi and Tn-seq | Journal of Bacteriology journals.asm.org/doi/10.1128/...
Reposted by Greg Harrison
NEW: Don't ask too many questions, but...
NIH may not re-terminate the 900ish grants at issue in the main NIH lawsuits after all.
To the PIs of reinstated grants, SPEND NOW!
🧵 Here's what NIH is probably thinking. Bear with me:
NIH may not re-terminate the 900ish grants at issue in the main NIH lawsuits after all.
To the PIs of reinstated grants, SPEND NOW!
🧵 Here's what NIH is probably thinking. Bear with me:
August 29, 2025 at 2:50 PM
NEW: Don't ask too many questions, but...
NIH may not re-terminate the 900ish grants at issue in the main NIH lawsuits after all.
To the PIs of reinstated grants, SPEND NOW!
🧵 Here's what NIH is probably thinking. Bear with me:
NIH may not re-terminate the 900ish grants at issue in the main NIH lawsuits after all.
To the PIs of reinstated grants, SPEND NOW!
🧵 Here's what NIH is probably thinking. Bear with me:
Reposted by Greg Harrison
Here we show that >90% of Paenibacillus encode a unique Spo0B with a transmembrane domain! TM domain helps it interact with its phosphorelay partners. Congrats to @isabellalin.bsky.social who left for grad school this week and her mentor @cassidyprints.bsky.social! www.biorxiv.org/content/10.1...
Conservation of sporulation genes and a transmembrane-containing Spo0B variant in Paenibacillus
Sporulation is a strategy employed by many bacteria to survive harsh environmental conditions. The genus Paenibacillus includes spore-forming species notorious for spoiling pasteurized dairy products ...
www.biorxiv.org
August 28, 2025 at 11:27 PM
Here we show that >90% of Paenibacillus encode a unique Spo0B with a transmembrane domain! TM domain helps it interact with its phosphorelay partners. Congrats to @isabellalin.bsky.social who left for grad school this week and her mentor @cassidyprints.bsky.social! www.biorxiv.org/content/10.1...
Reposted by Greg Harrison
Post a non-religious photo you think of as holy.
August 20, 2025 at 7:54 PM
Post a non-religious photo you think of as holy.
Reposted by Greg Harrison
New preprint from us! The latest part of our C. difficile vancomycin resistance story. We identified a new two-component system (VnrRS) that can control expression of the vanG pathway - just needs one amino acid change
@buddlejess.bsky.social @brockhurstlab.bsky.social @claireyt.bsky.social
@buddlejess.bsky.social @brockhurstlab.bsky.social @claireyt.bsky.social
A novel two-component system controls vancomycin resistance in epidemic Clostridioides difficile
The glycopeptide antibiotic vancomycin is the frontline treatment for C. difficile infection in the UK. There have been only sporadic reports of resistance in the clinic but testing is rare so the tru...
www.biorxiv.org
August 22, 2025 at 9:39 AM
New preprint from us! The latest part of our C. difficile vancomycin resistance story. We identified a new two-component system (VnrRS) that can control expression of the vanG pathway - just needs one amino acid change
@buddlejess.bsky.social @brockhurstlab.bsky.social @claireyt.bsky.social
@buddlejess.bsky.social @brockhurstlab.bsky.social @claireyt.bsky.social
😔
5-4 Supreme Court rules that NIH can terminate grants pending the full ruling.
thehill.com/regulation/c...
I have no (printable) words...
thehill.com/regulation/c...
I have no (printable) words...
a close up of a white dog 's face with red eyes
ALT: a close up of a white dog 's face with red eyes
media.tenor.com
August 21, 2025 at 11:39 PM
😔
Reposted by Greg Harrison
We are hiring! The Dept of Microbiology and Molecular Genetics is looking for faculty at the Assistant or Associate professor level (tenure track). Please consider joining our vibrant microbiology and immunology community at the University of Pittsburgh School of medicine
August 20, 2025 at 7:41 PM
We are hiring! The Dept of Microbiology and Molecular Genetics is looking for faculty at the Assistant or Associate professor level (tenure track). Please consider joining our vibrant microbiology and immunology community at the University of Pittsburgh School of medicine
Reposted by Greg Harrison
Elio Schaechter was one of my heroes. His 1958 paper with Ole Maaløe and Niels Kjeldgaard (fondly known as “SMK”) is a North Star for so much work in my group. A wonderful scientist, great communicator, and a very kind person. May his memory be a blessing.
August 15, 2025 at 3:40 PM
Elio Schaechter was one of my heroes. His 1958 paper with Ole Maaløe and Niels Kjeldgaard (fondly known as “SMK”) is a North Star for so much work in my group. A wonderful scientist, great communicator, and a very kind person. May his memory be a blessing.
Reposted by Greg Harrison
On Aug. 1, ASM & partner societies filed an expanded amicus brief with SCOTUS to defend scientific integrity & protect early-career researchers. The brief highlights the harm caused by NIH grant terminations, including canceling the MOSAIC program. asm.org/press-releas...
Scientific Societies File Supreme Court Amicus Brief in Support of NIH Grantees
ASM and fellow societies filed an amicus brief with the Supreme Court, calling for the swift restoration of NIH grant funding supporting early-career scientists, such as the MOSAIC program.
asm.org
August 4, 2025 at 9:23 PM
On Aug. 1, ASM & partner societies filed an expanded amicus brief with SCOTUS to defend scientific integrity & protect early-career researchers. The brief highlights the harm caused by NIH grant terminations, including canceling the MOSAIC program. asm.org/press-releas...
Reposted by Greg Harrison
The CspC:CspA heterodimer transduces germinant and co-germinant signals during Clostridioides difficile spore germination. https://www.biorxiv.org/content/10.1101/2025.08.01.668244v1
August 3, 2025 at 3:16 AM
The CspC:CspA heterodimer transduces germinant and co-germinant signals during Clostridioides difficile spore germination. https://www.biorxiv.org/content/10.1101/2025.08.01.668244v1
Reposted by Greg Harrison
Excited to share this collaborative study with @ritatamayo.bsky.social showing that E. faecalis influences C. diff morphology through the phase variable CmrRST system! This work was co-led by the amazing team of @ashleyweiss.bsky.social and Jilarie Santos-Santiago!
Enterococcus faecalis modulates phase variation in Clostridioides difficile https://www.biorxiv.org/content/10.1101/2025.07.24.666506v1
July 26, 2025 at 3:08 AM
Excited to share this collaborative study with @ritatamayo.bsky.social showing that E. faecalis influences C. diff morphology through the phase variable CmrRST system! This work was co-led by the amazing team of @ashleyweiss.bsky.social and Jilarie Santos-Santiago!
Reposted by Greg Harrison
Excited to post our first S. aureus preprint on biorxiv! Big congrats to co-first authors, postdocs @anjali20anil.bsky.social and Rezia Braza, and really enjoyed the collaboration with @torreslab.bsky.social !
Staphylococcus aureus exhibits spatiotemporal heterogeneity in Sae activity during kidney abscess development https://www.biorxiv.org/content/10.1101/2025.07.08.663646v1
July 10, 2025 at 1:17 AM
Excited to post our first S. aureus preprint on biorxiv! Big congrats to co-first authors, postdocs @anjali20anil.bsky.social and Rezia Braza, and really enjoyed the collaboration with @torreslab.bsky.social !