One in eight Canadians say they’ve been searching for a family doctor for more than a year - or have stopped looking altogether, according to new data from Angus Reid Institute.

The unions representing Nova Scotia teachers and support staff say school violence remains a top concern for its members, as the Education Department is reporting tens of thousands of violent incident...

A fundamental role for division orientation in progenitor output driving cortical and retinal growth is revealed.

Gamble et al. demonstrate that detection of stalled replication forks by the innate immune sensor IFI16 induces an early STING-dependent pro-inflammatory cytokine response independently of cGAS and DN...

Job reference code: IRCM-Cancer

A former Minnesota governor recently pitched a novel solution to the state’s clashes with the Trump administration: join Canada. He's not the first, nor only, one in the state looking north.

A genome duplication event during the Silurian played a crucial role in the evolutionary emergence of spinnerets in spiders.

How gene regulation strategies rapidly evolve across short evolutionary timescales is explored.

Long-overlooked Kepler signal discovered by citizen scientists reveals promising world worth a closer look

The role of the immune system in regulating organismal lifespan remains poorly understood. Here, we show that CD4⁺ T cells release “telomere Rivers” into circulation after acquiring telomeres from antigen-presenting cells (APCs). River formation requires fatty acid oxidation at the T cell–APC synapse, which selectively excludes glyceraldehyde 3-phosphate dehydrogenase (GAPDH) from the telomere vesicles. The resulting Rivers are depleted of glycolytic enzymes but enriched in T cell–derived stemness factors, enabling targeted rejuvenation of senescent tissues across multiple organs. In aged mice, adoptive transfer of young or metabolically reprogrammed CD4⁺ T cells triggered River production in vivo , and Rivers isolated from these animals could be transplanted into other aged mice to propagate the rejuvenation phenotype independently of T cells. River therapy extended median lifespan by ∼17 months, with several mice surviving to nearly five years. This immune-driven telomere transfer pathway is conserved across kingdoms, including plants, defining the first systemic, transplantable programme of youth. ### Competing Interest Statement A.L. is a shareholder to Sentcell ltd and the sole inventor of the DOS pharmaceutics (PCT/IT2021/000059) and of methods to generate artificial Rivers where Sentcell ltd figures as the Applicant. A.L. and F.R. are supported by Sentcell ltd.

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Radon gas, an invisible health threat that can build up in your home, is putting more Canadians at risk of deadly lung cancer. A national research team is using throwaway toenail clippings to find mar...