Dave Carlson
@davecarlson.bsky.social
PhD in EcoEvo. Bioinformatics & High Performance Computing. Transposon enthusiast.
The existence of pho alone makes the USA at least 75% more awesome than it would otherwise be.
Sixteen years in MN and I’ve never set foot in this miraculous place: a midwestern dive bar where everyone is Hmong, with an attached pool hall, EDM stage, and where you can order pho until midnight. The idea people would want to kick immigrants out of this region is insane.
January 31, 2026 at 3:31 PM
The existence of pho alone makes the USA at least 75% more awesome than it would otherwise be.
Reposted by Dave Carlson
Sixteen years in MN and I’ve never set foot in this miraculous place: a midwestern dive bar where everyone is Hmong, with an attached pool hall, EDM stage, and where you can order pho until midnight. The idea people would want to kick immigrants out of this region is insane.
January 31, 2026 at 4:55 AM
Sixteen years in MN and I’ve never set foot in this miraculous place: a midwestern dive bar where everyone is Hmong, with an attached pool hall, EDM stage, and where you can order pho until midnight. The idea people would want to kick immigrants out of this region is insane.
Reposted by Dave Carlson
The legendary Catherine O’Hara has died.
She was 71.
Per TMZ.
She was 71.
Per TMZ.
January 30, 2026 at 6:09 PM
The legendary Catherine O’Hara has died.
She was 71.
Per TMZ.
She was 71.
Per TMZ.
Reposted by Dave Carlson
Calling all OrthoFinder users!
We’ve just released GLADE, a tool to infer gene gains, losses, duplications, and ancestral genomes across a phylogeny.
GLADE runs directly on OrthoFinder results.
www.biorxiv.org/content/10.6...
github.com/lauriebelch/...
(1/10)
We’ve just released GLADE, a tool to infer gene gains, losses, duplications, and ancestral genomes across a phylogeny.
GLADE runs directly on OrthoFinder results.
www.biorxiv.org/content/10.6...
github.com/lauriebelch/...
(1/10)
www.biorxiv.org
January 29, 2026 at 12:07 PM
Calling all OrthoFinder users!
We’ve just released GLADE, a tool to infer gene gains, losses, duplications, and ancestral genomes across a phylogeny.
GLADE runs directly on OrthoFinder results.
www.biorxiv.org/content/10.6...
github.com/lauriebelch/...
(1/10)
We’ve just released GLADE, a tool to infer gene gains, losses, duplications, and ancestral genomes across a phylogeny.
GLADE runs directly on OrthoFinder results.
www.biorxiv.org/content/10.6...
github.com/lauriebelch/...
(1/10)
Reposted by Dave Carlson
I don't have anything to add to this moment that hasn't been said better by others. But I will say that I feel a level of rage that I have not experienced since the run up to the Iraq war. And I know that I am not alone in that. 1/n
January 25, 2026 at 3:47 PM
I don't have anything to add to this moment that hasn't been said better by others. But I will say that I feel a level of rage that I have not experienced since the run up to the Iraq war. And I know that I am not alone in that. 1/n
Reposted by Dave Carlson
I just want to say that 1) AltWatcher is doing the lord's work and 2) the altnps account, in my opinion, needs to be outright banned - and I don't say that merely because I loathe it, but because it's unbelievably unhealthy for this fake, plagiarizing, qanon-lite account to have this influence.
AltNPS posted about Alex Pretti's murder 25 times since this morning. During that time, they spread misinformation about the shooting, lied about knowing the shooter's name, and generally flooded the zone with shit.
They're trying to milk this story for all it's worth.
They're trying to milk this story for all it's worth.
January 25, 2026 at 7:04 AM
I just want to say that 1) AltWatcher is doing the lord's work and 2) the altnps account, in my opinion, needs to be outright banned - and I don't say that merely because I loathe it, but because it's unbelievably unhealthy for this fake, plagiarizing, qanon-lite account to have this influence.
Reposted by Dave Carlson
Pam Bondi just sent a letter to Minnesota officials saying ICE will leave if the state turns over its voter database to Trump.
Guess what? This has never been about safety or immigration. It’s a pretext for Trump to take over elections in swing states.
Guess what? This has never been about safety or immigration. It’s a pretext for Trump to take over elections in swing states.
January 25, 2026 at 12:35 AM
Pam Bondi just sent a letter to Minnesota officials saying ICE will leave if the state turns over its voter database to Trump.
Guess what? This has never been about safety or immigration. It’s a pretext for Trump to take over elections in swing states.
Guess what? This has never been about safety or immigration. It’s a pretext for Trump to take over elections in swing states.
Reposted by Dave Carlson
The Senate should not vote to keep funding this rampage. We are not powerless. We do not need to accept this.
January 24, 2026 at 10:41 PM
The Senate should not vote to keep funding this rampage. We are not powerless. We do not need to accept this.
Reposted by Dave Carlson
Reminder: All it would take to end the murder of American citizens by an untrained government goon squad is 16 Republicans in Congress voting with Dems to defund ICE (or 23 to impeach and remove Trump — 3 in House & 20 in Senate). That’s it. 23 Americans can vote for the public and end all of this.
January 24, 2026 at 6:26 PM
Reminder: All it would take to end the murder of American citizens by an untrained government goon squad is 16 Republicans in Congress voting with Dems to defund ICE (or 23 to impeach and remove Trump — 3 in House & 20 in Senate). That’s it. 23 Americans can vote for the public and end all of this.
Reposted by Dave Carlson
I don’t want to hear anything from an elected official unless it’s a plan to defund the DHS and impeach Noem, Bovino, etc. No texts. No emails. No talk about the economy. Step up or step off.
January 24, 2026 at 7:23 PM
I don’t want to hear anything from an elected official unless it’s a plan to defund the DHS and impeach Noem, Bovino, etc. No texts. No emails. No talk about the economy. Step up or step off.
Reposted by Dave Carlson
Attention folks in the weather, climate, disaster, wildfire, and Earth science communities: NSF has just published a new "Dear Colleague" letter inviting feedback (by Mar 13) on the proposal to dismantle the National Center for Atmospheric Research (NCAR). www.nsf.gov/funding/...
January 23, 2026 at 9:57 PM
Attention folks in the weather, climate, disaster, wildfire, and Earth science communities: NSF has just published a new "Dear Colleague" letter inviting feedback (by Mar 13) on the proposal to dismantle the National Center for Atmospheric Research (NCAR). www.nsf.gov/funding/...
Reposted by Dave Carlson
in case you're curious about how angry Minnesota is about ICE, it was -20 today
January 24, 2026 at 12:38 AM
in case you're curious about how angry Minnesota is about ICE, it was -20 today
Reposted by Dave Carlson
Reposted by Dave Carlson
His name is Liam Ramos, and he is 5. He was abducted from Minneapolis and trafficked to a detention camp in Texas.
This picture making the rounds on reddit, Columbia Heights. I'm not OK.
January 21, 2026 at 11:27 PM
His name is Liam Ramos, and he is 5. He was abducted from Minneapolis and trafficked to a detention camp in Texas.
Reposted by Dave Carlson
The US granted visas to Jews but only allowed 30,000 in from Germany a year. You had to wait for your number to come up.
Meet Robert Smallbones. An unassuming British diplomat who 'hacked' this system so effectively (saving 48 THOUSAND Jews) the UK government kept his scheme secret for decades /1 🧵
Meet Robert Smallbones. An unassuming British diplomat who 'hacked' this system so effectively (saving 48 THOUSAND Jews) the UK government kept his scheme secret for decades /1 🧵
January 21, 2026 at 12:52 PM
The US granted visas to Jews but only allowed 30,000 in from Germany a year. You had to wait for your number to come up.
Meet Robert Smallbones. An unassuming British diplomat who 'hacked' this system so effectively (saving 48 THOUSAND Jews) the UK government kept his scheme secret for decades /1 🧵
Meet Robert Smallbones. An unassuming British diplomat who 'hacked' this system so effectively (saving 48 THOUSAND Jews) the UK government kept his scheme secret for decades /1 🧵
Reposted by Dave Carlson
This is the most astonishing graph of what the Trump regime has done to US science. They have destroyed the federal science workforce across the board. The negative impacts on Americans will be felt for generations, and the US might never be the same again.
www.nature.com/immersive/d4...
www.nature.com/immersive/d4...
January 20, 2026 at 10:53 PM
This is the most astonishing graph of what the Trump regime has done to US science. They have destroyed the federal science workforce across the board. The negative impacts on Americans will be felt for generations, and the US might never be the same again.
www.nature.com/immersive/d4...
www.nature.com/immersive/d4...
Reposted by Dave Carlson
Reposted by Dave Carlson
New blog post! Running nf-core pipelines on ARM
https://nf-co.re/blog/2026/arm-pipelines/
https://nf-co.re/blog/2026/arm-pipelines/
January 17, 2026 at 11:01 PM
New blog post! Running nf-core pipelines on ARM
https://nf-co.re/blog/2026/arm-pipelines/
https://nf-co.re/blog/2026/arm-pipelines/
Reposted by Dave Carlson
I think it’s really important for those of us who do not live in the Twin Cities to read this.
Please share this!
I sent a version of these stories (before this was published today) to a non-Minnesota work network, w donation links, & asked people to share what’s happening
Just got an email from someone who sent it to her mom, who sent it to her church, where it‘s inspiring resistance plans
I sent a version of these stories (before this was published today) to a non-Minnesota work network, w donation links, & asked people to share what’s happening
Just got an email from someone who sent it to her mom, who sent it to her church, where it‘s inspiring resistance plans
Dispatch from the occupation
What life is like in Minneapolis now
donmoynihan.substack.com
January 17, 2026 at 7:14 PM
I think it’s really important for those of us who do not live in the Twin Cities to read this.
Reposted by Dave Carlson
Photo by Pierre Lavie. Yes this is me. And I threw my Leica. It landed on the bass plate with hardly a scratch. Another Photographer grabbed it along with my phone and I was able to track him later. I was held face down tear gas deployed right in front of me and pepper sprayed directly into the eye.
January 17, 2026 at 2:57 PM
Photo by Pierre Lavie. Yes this is me. And I threw my Leica. It landed on the bass plate with hardly a scratch. Another Photographer grabbed it along with my phone and I was able to track him later. I was held face down tear gas deployed right in front of me and pepper sprayed directly into the eye.
I just tried explaining Will Stancil to my wife. It didn't go very well.
January 17, 2026 at 3:13 AM
I just tried explaining Will Stancil to my wife. It didn't go very well.
Reposted by Dave Carlson
Gift link - we all need to read this. Shoot this Resistance into my veins!
After 48 hours of torture, Dr. Christie wrote a forced confession — “the best thing I ever wrote,” he later told the BBC
www.nytimes.com/2026/01/14/w...
After 48 hours of torture, Dr. Christie wrote a forced confession — “the best thing I ever wrote,” he later told the BBC
www.nytimes.com/2026/01/14/w...
Renfrew Christie Dies at 76; Sabotaged Racist Regime’s Nuclear Program
www.nytimes.com
January 15, 2026 at 5:29 PM
Gift link - we all need to read this. Shoot this Resistance into my veins!
After 48 hours of torture, Dr. Christie wrote a forced confession — “the best thing I ever wrote,” he later told the BBC
www.nytimes.com/2026/01/14/w...
After 48 hours of torture, Dr. Christie wrote a forced confession — “the best thing I ever wrote,” he later told the BBC
www.nytimes.com/2026/01/14/w...
Reposted by Dave Carlson
I want to talk about a dystopian world we are entering - where every moment, event, and crisis just become commodities.
Life stops being something we live, but something we sell and trade. It will breed both corruption & emptiness.
1/ A 🧵on why our politics can't ignore this.
Life stops being something we live, but something we sell and trade. It will breed both corruption & emptiness.
1/ A 🧵on why our politics can't ignore this.
January 14, 2026 at 10:59 PM
I want to talk about a dystopian world we are entering - where every moment, event, and crisis just become commodities.
Life stops being something we live, but something we sell and trade. It will breed both corruption & emptiness.
1/ A 🧵on why our politics can't ignore this.
Life stops being something we live, but something we sell and trade. It will breed both corruption & emptiness.
1/ A 🧵on why our politics can't ignore this.
Reposted by Dave Carlson
I am looking for a postdoc to develop high-performance algorithms in computational genomics. Email or DM me if interested. For more information, see hlilab.github.io/vacancies. RTs appreciated!
HLi Lab - Vacancies
Openings
hlilab.github.io
January 14, 2026 at 3:44 PM
I am looking for a postdoc to develop high-performance algorithms in computational genomics. Email or DM me if interested. For more information, see hlilab.github.io/vacancies. RTs appreciated!