Dave Carlson
@davecarlson.bsky.social
PhD in EcoEvo. Bioinformatics & High Performance Computing. Transposon enthusiast.
Reposted by Dave Carlson
This is one of the most remarkable academic debacles I've ever seen.
A large RCT got published in BMJ. There are currently 44 Pubpeer comments, mostly about the data, including...well. Read for yourself.
pubpeer.com/publications...
A large RCT got published in BMJ. There are currently 44 Pubpeer comments, mostly about the data, including...well. Read for yourself.
pubpeer.com/publications...
PubPeer - Prevention of acute myocardial infarction induced heart fail...
There are comments on PubPeer for publication: Prevention of acute myocardial infarction induced heart failure by intracoronary infusion of mesenchymal stem cells: phase 3 randomised clinical trial (P...
pubpeer.com
November 11, 2025 at 1:19 AM
This is one of the most remarkable academic debacles I've ever seen.
A large RCT got published in BMJ. There are currently 44 Pubpeer comments, mostly about the data, including...well. Read for yourself.
pubpeer.com/publications...
A large RCT got published in BMJ. There are currently 44 Pubpeer comments, mostly about the data, including...well. Read for yourself.
pubpeer.com/publications...
November 10, 2025 at 2:33 AM
Reposted by Dave Carlson
Prescient
Chris Murphy: "There will be pretty substantial damage to a Dem brand that has been rehabilitated if on the heels of an election in which the people told us to keep fighting, we immediately stop... if we surrender without having gotten anything, I worry it'll be hard to get them back up off the mat"
November 10, 2025 at 2:19 AM
Prescient
We'll have to see how the votes shake out, but these are the D senators up for reelection next year
Source: www.senate.gov/senators/Cla...
Source: www.senate.gov/senators/Cla...
November 10, 2025 at 12:41 AM
We'll have to see how the votes shake out, but these are the D senators up for reelection next year
Source: www.senate.gov/senators/Cla...
Source: www.senate.gov/senators/Cla...
Reposted by Dave Carlson
If Dems cave on health care subsidies, I might actually lose my fucking mind.
"A vote in Senate on the issue" is 1000% meaningless.
"A vote in Senate on the issue" is 1000% meaningless.
From what I have seen so far this does not seem like a good deal:
November 9, 2025 at 8:11 PM
If Dems cave on health care subsidies, I might actually lose my fucking mind.
"A vote in Senate on the issue" is 1000% meaningless.
"A vote in Senate on the issue" is 1000% meaningless.
My wife and I disagree frequently about what version of "Landslide" is better. She prefers the original, while I think that the Chicks cover is better.
I need you all to settle the debate - what version of Landslide is the best? Fleetwood, Chicks, Pumpkins, some other?
I need you all to settle the debate - what version of Landslide is the best? Fleetwood, Chicks, Pumpkins, some other?
November 8, 2025 at 6:42 PM
My wife and I disagree frequently about what version of "Landslide" is better. She prefers the original, while I think that the Chicks cover is better.
I need you all to settle the debate - what version of Landslide is the best? Fleetwood, Chicks, Pumpkins, some other?
I need you all to settle the debate - what version of Landslide is the best? Fleetwood, Chicks, Pumpkins, some other?
Reposted by Dave Carlson
JOIN US LIVE FOR THE WORLD CUP 2026 DRAW 🏆
Dec. 5 we'll be LIVE at Manhattan Center's Grand Ballroom with our great friends at Verizon to watch, react to, & dissect the World Cup Draw with special guests, bold predictions, & unbridled joy.
🎟️ Tickets: mibcourage.co/4oXgXdm
Dec. 5 we'll be LIVE at Manhattan Center's Grand Ballroom with our great friends at Verizon to watch, react to, & dissect the World Cup Draw with special guests, bold predictions, & unbridled joy.
🎟️ Tickets: mibcourage.co/4oXgXdm
November 7, 2025 at 3:17 PM
JOIN US LIVE FOR THE WORLD CUP 2026 DRAW 🏆
Dec. 5 we'll be LIVE at Manhattan Center's Grand Ballroom with our great friends at Verizon to watch, react to, & dissect the World Cup Draw with special guests, bold predictions, & unbridled joy.
🎟️ Tickets: mibcourage.co/4oXgXdm
Dec. 5 we'll be LIVE at Manhattan Center's Grand Ballroom with our great friends at Verizon to watch, react to, & dissect the World Cup Draw with special guests, bold predictions, & unbridled joy.
🎟️ Tickets: mibcourage.co/4oXgXdm
I am once again begging research software engineers to google their application's acronym before publication.
November 7, 2025 at 1:47 PM
I am once again begging research software engineers to google their application's acronym before publication.
4 billion years of evolution >>> 4, 40, or 400 billion dollars
My favorite comment on the FT story
November 6, 2025 at 10:00 PM
4 billion years of evolution >>> 4, 40, or 400 billion dollars
Reposted by Dave Carlson
The detectCores() apocalypse is creeping up on us 👻🐛
As more people are getting access to 128+ CPU cores, code spinning up parallel cluster with detectCores() workers fails - not enough #RStats connections available
Friends, do *not* default to detectCores(), bc www.jottr.org/2022/12/05/a...
As more people are getting access to 128+ CPU cores, code spinning up parallel cluster with detectCores() workers fails - not enough #RStats connections available
Friends, do *not* default to detectCores(), bc www.jottr.org/2022/12/05/a...
Please Avoid detectCores() in your R Packages
The detectCores() function of the parallel package is probably one of the most used functions when it comes to setting the number of parallel workers to use in R. In this blog post, I’ll try to explai...
www.jottr.org
November 5, 2025 at 11:55 PM
The detectCores() apocalypse is creeping up on us 👻🐛
As more people are getting access to 128+ CPU cores, code spinning up parallel cluster with detectCores() workers fails - not enough #RStats connections available
Friends, do *not* default to detectCores(), bc www.jottr.org/2022/12/05/a...
As more people are getting access to 128+ CPU cores, code spinning up parallel cluster with detectCores() workers fails - not enough #RStats connections available
Friends, do *not* default to detectCores(), bc www.jottr.org/2022/12/05/a...
Reposted by Dave Carlson
The detail on these is gonna get destroyed by the image compression on this app but it was fun to make them, especially putting the subway lines in.
November 5, 2025 at 10:48 PM
The detail on these is gonna get destroyed by the image compression on this app but it was fun to make them, especially putting the subway lines in.
Reposted by Dave Carlson
The shift in Connecticut tonight is seismic. Possibly unprecedented. Loads of towns flipped from Republican to Democratic control.
A partial list:
Ansonia
Bethany
Branford
Bristol
Brooklyn
East Granby
Ellington
Enfield
Farmington
Milford
New Britain
New Fairfield
Norwich
Plymouth
Rocky Hill
A partial list:
Ansonia
Bethany
Branford
Bristol
Brooklyn
East Granby
Ellington
Enfield
Farmington
Milford
New Britain
New Fairfield
Norwich
Plymouth
Rocky Hill
November 5, 2025 at 9:51 AM
The shift in Connecticut tonight is seismic. Possibly unprecedented. Loads of towns flipped from Republican to Democratic control.
A partial list:
Ansonia
Bethany
Branford
Bristol
Brooklyn
East Granby
Ellington
Enfield
Farmington
Milford
New Britain
New Fairfield
Norwich
Plymouth
Rocky Hill
A partial list:
Ansonia
Bethany
Branford
Bristol
Brooklyn
East Granby
Ellington
Enfield
Farmington
Milford
New Britain
New Fairfield
Norwich
Plymouth
Rocky Hill
I really hate that we can't make "hang that in the Louvre" jokes anymore.
November 4, 2025 at 4:57 PM
I really hate that we can't make "hang that in the Louvre" jokes anymore.
Reposted by Dave Carlson
The New York Post made this image about rich people fleeing Mamdani and, as someone familiar with both cities, I will say: haha ok
November 3, 2025 at 11:53 AM
The New York Post made this image about rich people fleeing Mamdani and, as someone familiar with both cities, I will say: haha ok
Reposted by Dave Carlson
NYC is going to have the world's biggest media-manufactured crime panic in history the second Mamdani is elected. They aren't even going to wait until he is inaugurated. Whether or not you like the guy, you need to start preparing now for the fire hose of disinformation that is about to activate.
November 2, 2025 at 11:19 PM
NYC is going to have the world's biggest media-manufactured crime panic in history the second Mamdani is elected. They aren't even going to wait until he is inaugurated. Whether or not you like the guy, you need to start preparing now for the fire hose of disinformation that is about to activate.
Reposted by Dave Carlson
Stony Brook is hiring an Assistant or Associate Professor in Marine Molecular Ecology (assistant encouraged, molecular broadly defined, includes microbial omics!): apply.interfolio.com/174869
Apply - Interfolio
{{$ctrl.$state.data.pageTitle}} - Apply - Interfolio
apply.interfolio.com
October 7, 2025 at 6:38 PM
Stony Brook is hiring an Assistant or Associate Professor in Marine Molecular Ecology (assistant encouraged, molecular broadly defined, includes microbial omics!): apply.interfolio.com/174869
Reposted by Dave Carlson
Let's do it. Let's get rid of the filibuster. Big step forward and actually the best possible circumstances for Ds. They've spent a month using their power to put draconian health care cuts at the top of the agenda. But ... I'm skeptical the GOP senate will go along. We'll see.
October 31, 2025 at 12:34 PM
Let's do it. Let's get rid of the filibuster. Big step forward and actually the best possible circumstances for Ds. They've spent a month using their power to put draconian health care cuts at the top of the agenda. But ... I'm skeptical the GOP senate will go along. We'll see.
Nothing sends chills down my millennial spine like the words "repackaged into a financial instrument." Happy Halloween!
so @matteowong.bsky.social & I wrote on data centers: arguably the most important buildings in the world & are, in a way, holding the economy hostage. Byzantine financial instruments, private equity, depreciating tech, hype, $trillion valuations. it’s all there. an ai crash prob starts here.
Here’s How the AI Crash Happens
The U.S. is becoming an Nvidia-state.
www.theatlantic.com
October 31, 2025 at 11:51 AM
Nothing sends chills down my millennial spine like the words "repackaged into a financial instrument." Happy Halloween!
Reposted by Dave Carlson
so @matteowong.bsky.social & I wrote on data centers: arguably the most important buildings in the world & are, in a way, holding the economy hostage. Byzantine financial instruments, private equity, depreciating tech, hype, $trillion valuations. it’s all there. an ai crash prob starts here.
Here’s How the AI Crash Happens
The U.S. is becoming an Nvidia-state.
www.theatlantic.com
October 30, 2025 at 10:25 PM
so @matteowong.bsky.social & I wrote on data centers: arguably the most important buildings in the world & are, in a way, holding the economy hostage. Byzantine financial instruments, private equity, depreciating tech, hype, $trillion valuations. it’s all there. an ai crash prob starts here.
Reposted by Dave Carlson
Birds but they get spookier each time. 🎃👻
Enter if you dare...🚪
Enter if you dare...🚪
October 31, 2025 at 9:24 AM
Birds but they get spookier each time. 🎃👻
Enter if you dare...🚪
Enter if you dare...🚪
Reposted by Dave Carlson
Yeah uh this is why I refuse to cede Tolkien to these people actually
DHS just posted a Lord of the Rings meme as an appeal to join ICE
October 30, 2025 at 4:02 PM
Yeah uh this is why I refuse to cede Tolkien to these people actually
Reposted by Dave Carlson
New from me: Everything is awful, so treat yourself to a timeline cleanse by hopping on the best train ride in the world, the Bernina Express.
donmoynihan.substack.com/p/all-aboard...
donmoynihan.substack.com/p/all-aboard...
All aboard the best train ride in the world
No timeline cleanse like a Swiss timeline cleanse
donmoynihan.substack.com
October 30, 2025 at 12:49 PM
New from me: Everything is awful, so treat yourself to a timeline cleanse by hopping on the best train ride in the world, the Bernina Express.
donmoynihan.substack.com/p/all-aboard...
donmoynihan.substack.com/p/all-aboard...
Reposted by Dave Carlson
50 years ago, King & Wilson published a foundational paper that underlies the cis-regulatory paradigm (CRP) of #DevoEvo #EvoDevo, i.e., that *almost* all morphological evolution is driven by mutations in regulatory elements, rather than proteins, and it all arose from simple misunderstanding 🧪 🧵
October 29, 2025 at 12:35 AM
Reposted by Dave Carlson
Excuse me? So the company the President currently owns is teaming up with a cryptocurrency company to create a prediction market, which will take bets... on things the President himself has quite a lot of control over?
Gosh, I'm sure nothing bad will happen.
www.ft.com/content/4855...
Gosh, I'm sure nothing bad will happen.
www.ft.com/content/4855...
October 29, 2025 at 4:02 AM
Excuse me? So the company the President currently owns is teaming up with a cryptocurrency company to create a prediction market, which will take bets... on things the President himself has quite a lot of control over?
Gosh, I'm sure nothing bad will happen.
www.ft.com/content/4855...
Gosh, I'm sure nothing bad will happen.
www.ft.com/content/4855...
Reposted by Dave Carlson
I heard that Zohran Mamdani called neccessity the “mother” of invention, even though neither necessity nor invention are biological units capable of being a “mother” or “child”.
October 28, 2025 at 8:57 PM
I heard that Zohran Mamdani called neccessity the “mother” of invention, even though neither necessity nor invention are biological units capable of being a “mother” or “child”.