Andrew Barentine
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barentine.bsky.social
Andrew Barentine
@barentine.bsky.social
postdoc in the Moerner lab
i heart bikes and microscopes
Reposted by Andrew Barentine
Just channeling Stephen J Gould: "I am, somehow, less interested in the weight and convolutions of Einstein's brain than in the near certainty that people of equal talent have lived and died in cotton fields and sweatshops"
November 8, 2025 at 12:12 AM
Reposted by Andrew Barentine
We've now discovered some neat cell culture dishes that feature a 50 micron thick film of a proprietary polymer with refractive index even closer to water than FEP. They work just as well as our homemade FEP assembly and are available in multiwell plate format too!

www.sarstedt.com/en/products/...
October 28, 2025 at 8:27 PM
Reposted by Andrew Barentine
We present multi-immersion Oblique Plane microscope (miOPM), a light-sheet platform that can be adapted to a wide range of applications, from sensitive live cell imaging to imaging organs and cleared tissues.
www.biorxiv.org/content/10.1...
October 6, 2025 at 5:52 PM
Reposted by Andrew Barentine
🚨 2 × PhD positions @EPFL! 🚨
Help us push the boundaries of fluorescence microscopy - DNA nanotech, custom optics & spatial omics in Lausanne 🇨🇭. Start Jan 2026. Send CV + motivation + 2 refs → fschueder@ethz.ch
#PhD #Hiring #microscopy #SuperResolution #SpatialOmics #DNAPAINT #FLASHPAINT
July 31, 2025 at 8:56 AM
Reposted by Andrew Barentine
Our ‘Cell Scientist to Watch’ is Francesca Bottanelli @franbottanelli.bsky.social‬. We discover more about Fran’s career path, her approach to scientific mentorship and her dream to start a band!
journals.biologists.com/jcs/article/...
June 4, 2025 at 2:08 PM
I love the weekend
May 26, 2025 at 3:10 AM
Reposted by Andrew Barentine
The AQLM Queens of Super-res lead evening discussion. Dr. Gustavsson and Dr. Lidke help us figure out how to look REALLY close. #AQLM2025

@gustavssonlab.bsky.social
@aqlm.bsky.social
May 7, 2025 at 2:49 AM
Reposted by Andrew Barentine
Well, maybe the children will have to live with two cures instead of 30 cures.
May 1, 2025 at 3:08 PM
Reposted by Andrew Barentine
Everyone please read and act! 👇
ACTION ITEM-----ACTION ITEM

Implementation of Schedule F

This is what a lot of us have been worried about.

This allows for many civil service positions to replaced with political appointees. This could include NIH institute directors and even POs.

BUT THERE IS A COMMENT PERIOD...

1/n
the word alert is in a purple circle
ALT: the word alert is in a purple circle
media.tenor.com
April 23, 2025 at 9:00 PM
Reposted by Andrew Barentine
Whew! Hakeem had time today, and you should read what he had to say. This piece is excellent!
April 23, 2025 at 1:53 AM
Nice work @zacsimile.bsky.social - interesting results!
MINFLUX works well in theory, but system and sample imperfections can lead to suboptimal resolution. To address this, @jonasries.bsky.social and I developed SimuFLUX: www.biorxiv.org/content/10.1..., a realistic simulator to optimize MINFLUX experiments before samples go on the microscope.
Evaluating MINFLUX experimental performance in silico
MINFLUX is a super-resolution microscopy technique with remarkable resolution for imaging and tracking. Its optical resolution is well understood under idealized conditions, but because of system comp...
www.biorxiv.org
April 9, 2025 at 5:43 PM
Reposted by Andrew Barentine
I was invited, for July, to a scienctific meeting in Telluride (Colorado). I was told it is a wonderful place for a conference, and I was very much looking forward to an exciting meeting in a fantastic environment. I have just canceled my participation, despite having booked already everything.
French scientist denied US entry after phone messages critical of Trump found
France’s research minister said the scientist was traveling to Houston for a conference when his phone was searched
www.theguardian.com
March 23, 2025 at 10:44 AM
Reposted by Andrew Barentine
Your weekly reminder that it is not ok to out or misgender trans or nonbinary individuals whether it is in a public forum, workplace, or anywhere else. It’s harassment, and a real distraction from everything else.
Republican Rep. Keith Self called on Rep. Sarah McBride, referring to her as “Mr. McBride,” and Democratic Rep. William Keating quickly jumped to her defense.

The hostility and abuse Sarah McBride is consistently subjected to by her colleagues is disgusting.
March 12, 2025 at 7:32 PM
Reposted by Andrew Barentine
By putting a donut between our faces and each article we read, we were able to extract more information than ever before about MINFLUX. You can read the new review article from @maxperutzlabs.bsky.social by Lukas Scheiderer, myself, and @jonasries.bsky.social at www.nature.com/articles/s41...
MINFLUX achieves molecular resolution with minimal photons - Nature Photonics
The authors review MINFLUX super-resolution microscopy, outlining its advantages and limitations, recent progress, and an outlook for future developments.
www.nature.com
March 10, 2025 at 3:14 PM
It’s a beautiful day to #StandUpForScience
March 7, 2025 at 9:23 PM
Reposted by Andrew Barentine
We all owe @jeremymberg.bsky.social a debt of gratitude for his work in clarifying, connecting, and advocating for science in this chaotic time.

🙏🏼
I have spent many hours over the past two days speaking with reporters from major outlets, linking them to public and not-so-public documents, and connecting them with other folks. I hope there will be lots coming out soon.
Yes thanks! How can we get this into bigger news outlets?
February 21, 2025 at 12:12 AM
nothing wakes you up like getting your representative’s office on the phone over your morning coffee
February 19, 2025 at 4:23 PM
Reposted by Andrew Barentine
In our work, we just put the camera directly into the remote refocus volume to detect the oblique plane directly, without the need for a tertiary microscope system!
February 12, 2025 at 4:41 PM
Reposted by Andrew Barentine
The self-driving multiscale microscope from @daetwylerstephan.bsky.social is out.

It can image an entire zebrafish embryo longitudinally and follow a volume of interest over time with high resolution.

We used it to study cancer-immune cell interactions.

www.nature.com/articles/s41...
Imaging of cellular dynamics from a whole organism to subcellular scale with self-driving, multiscale microscopy
Nature Methods - A self-driving multiresolution light-sheet microscope enables the simultaneous observation and quantification of cellular and subcellular dynamics in the context of intact and...
www.nature.com
February 12, 2025 at 1:45 PM
Reposted by Andrew Barentine
Ardem, I am sorry. In this middle of this chaos, HHMI will always hold the dubious distinction of being the first organization, federal or private, to cut an ongoing and funded DEI program. In the darkest hour, it ran for the hills. As a member of those groups, I can’t tell you how painful this is.
Folks, let’s not be too quick to blame. HHMI is a progressive institution with strong leadership, doing what it can while navigating legal challenges. They get top legal advice on what’s possible, and these are tough times. Let’s not demonize one of the good ones!
Got a message today that HHMI remains deeply committed to the existing research programs that include the Investigator, Freeman Hrabowski Scholar, Hanna Gray Fellows, and Gilliam Fellow programs: "We do not anticipate changes to these or any other research or science education programs at HHMI."
February 7, 2025 at 8:36 PM
Reposted by Andrew Barentine
I urge everyone to read this concise but very complete history of what's been happening at our nation's science agencies the past few years, I mean days, by @dereklowe.bsky.social www.science.org/content/blog... TY Derek
What's Happening Inside the NIH and NSF
www.science.org
February 4, 2025 at 5:26 PM
Reposted by Andrew Barentine
Incredible new work from Yongdeng Zhang demonstrating live 4Pi SIM--and in two colors! www.nature.com/articles/s41...
Elucidating subcellular architecture and dynamics at isotropic 100-nm resolution with 4Pi-SIM - Nature Methods
The 4Pi-SIM microscope combines the benefits of structured illumination microscopy with 4Pi geometry for improved axial resolution, offering isotropic, multicolor super-resolution imaging of dynamic p...
www.nature.com
December 24, 2024 at 1:47 PM
Reposted by Andrew Barentine
Reading the paper in Cell about how to close the scissor plots in gender representation at senior academic positions, I feel just a touch of pessimism. Having reached a level of seniority (middle management) I didn’t think I ever would, I read these great ideas wanting more, much more /1.
Closing the scissor-shaped curve: Strategies to promote gender equality in academia
Gender inequality in STEM fields remains pervasive and undermines the ability for talented individuals to excel. Despite advances, women still encounter obstacles in pursuing academic careers and reac...
www.cell.com
December 1, 2024 at 4:12 AM
Anyone have experience with this #MicroscopistNightmares? This table is warped in several (many?) places. Is it silly to worry about further warping and alignment instability?
November 21, 2024 at 5:48 AM
Reposted by Andrew Barentine
Hey #microscopy Bsky… what is that xz wormy PSF 😭😭😭😭
November 18, 2024 at 7:42 PM