#haematopoiesis
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dev-journal.bsky.social
The most recent addition to our academic team, Associate Editor Anna Bigas, will be speaking at the Dubai Stem Cell Congress that starts next week on Saturday 7 February.

Chat with Anna about publishing #haematopoiesis in Development.

journals.biologists.com/dev/pages/ed...
Anna Bigas Associate Editor, Development Hospital del Mar Research Institute (HMRIB) and Josep Carreras Leukaemia Research Institute (IJC), Spain “I look forward to handling papers on developmental haematopoiesis and haematopoietic stem cells. I can also handle Notch signalling papers in different systems, as well as papers on cancer and leukaemia mechanisms.” Key topics: development and disease haematopoiesis signalling stem cells
January 26, 2026 at 1:08 PM
novogene-europe.bsky.social
Explore Novogene's case study: CRISPR/dCas9 DNA methylation editing in human HSPCs shows heritable p15 hypermethylation affects haematopoiesis in vivo. See methods, results & implications. #Epigenetics #CRISPR #Hematopoiesis https://bit.ly/46WD8sP
January 21, 2026 at 8:05 AM
natrevmcb.nature.com
ICYMI: New Online! Inflammageing and clonal haematopoiesis interplay and their impact on human disease
Inflammageing and clonal haematopoiesis interplay and their impact on human disease
Nature Reviews Molecular Cell Biology, Published online: 06 January 2026; doi:10.1038/s41580-025-00936-yClonal haematopoiesis of indeterminate potential (CHIP) is an ageing-related condition associated with a substantial fraction of leukocytes descending from a single somatically mutated haematopoietic stem cell. This Review discusses the molecular and cellular mechanisms that cause CHIP, its interplay with inflammageing, and the pathophysiological consequences and translational implications for older individuals.
dlvr.it
January 9, 2026 at 1:23 AM
bigearthdata.ai
Inflammageing and Clonal Haematopoiesis: Disease Connections
->Bioengineer | #disease #health | More from Lil Dr Glen EcoChat at BigEarthData.ai
Inflammageing and Clonal Haematopoiesis: Disease Connections
Clonal haematopoiesis of indeterminate potential (CHIP) is emerging as a significant area of investigation within the context of age-related diseases, particularly those affecting the hematological system and chronic inflammatory conditions. As the global population ages, understanding the mechanisms driving CHIP...
bioengineer.org
January 6, 2026 at 1:13 PM
natrevmcb.nature.com
New Online! Inflammageing and clonal haematopoiesis interplay and their impact on human disease
Inflammageing and clonal haematopoiesis interplay and their impact on human disease
Nature Reviews Molecular Cell Biology, Published online: 06 January 2026; doi:10.1038/s41580-025-00936-yClonal haematopoiesis of indeterminate potential (CHIP) is an ageing-related condition associated with a substantial fraction of leukocytes descending from a single somatically mutated haematopoietic stem cell. This Review discusses the molecular and cellular mechanisms that cause CHIP, its interplay with inflammageing, and the pathophysiological consequences and translational implications for older individuals.
bit.ly
January 6, 2026 at 1:21 AM
romanmdoll.bsky.social
To further validate that edited CD34+ cells retain normal haematopoiesis, we engrafted these cells into a bone marrow organoid system. We saw normal multilineage myeloid differentiation and deep and persistent drops in VAF – as much as 99% down from the baseline burden!
December 20, 2025 at 9:37 AM
romanmdoll.bsky.social
Since MPNs originate from stem cells, it should be possible to genetically delete V617F alleles from CD34+ cells. If we can do this allele-selectively (AS) for the V617F alleles, we should selectively suppress mutant effects while preserving haematopoiesis from wildtype alleles.
December 20, 2025 at 9:37 AM
imm.ox.ac.uk
More about the De Bruijn Group → www.imm.ox.ac.uk/research/res...

#WIMMSpotlight #WIMMCommunity #DevelopmentalBiology #Haematopoiesis #Immunity #EmbryonicDevelopment #MRCWIMM
de Bruijn Group: Developmental Haematopoiesis
We study the embryonic origins of blood stem cells with the aim to inform the generation of these cells in culture, and ultimate produce clinically relevant blood stem cells for therapeutic purposes.
www.imm.ox.ac.uk
December 9, 2025 at 9:48 AM
imm.ox.ac.uk
She is particularly interested in uncovering the contributions of blood precursors uniquely generated in the embryo that persist into late fetal and postnatal life, playing important roles in haematopoiesis and immunity.
December 9, 2025 at 9:48 AM
biorxiv-molbio.bsky.social
Mammalian PABPC4 is non-essential, but has roles in growth, post-natal survival and haematopoiesis. https://www.biorxiv.org/content/10.1101/2025.11.22.689676v1
November 24, 2025 at 3:17 AM
biorxivpreprint.bsky.social
Mammalian PABPC4 is non-essential, but has roles in growth, post-natal survival and haematopoiesis. https://www.biorxiv.org/content/10.1101/2025.11.22.689676v1
November 24, 2025 at 3:17 AM
milnerinst.bsky.social
📣 Milner Seminars: Focus on haematopoiesis🩸

Please join us Tomorrow for the next instalment of our seminar series, with talks from Adam Wilkinson and Cédric Ghevaert from Cambridge Stem Cell.

View talk titles and register: milner.glueup.com/event/milner-seminars-focus-on-haematopoiesis-158139/
November 18, 2025 at 3:14 PM
milnerinst.bsky.social
📣 Milner Seminars: Focus on haematopoiesis🩸

Please join us Tomorrow for the next instalment of our seminar series, with talks from Adam Wilkinson and Cédric Ghevaert from @scicambridge.bsky.social.

View talk titles and register: milner.glueup.com/ev...
November 18, 2025 at 8:00 AM
milnerinst.bsky.social
📣 Milner Seminars: Focus on haematopoiesis🩸

Please join us on 19 November for the next instalment of our seminar series, with talks from Adam Wilkinson and Cédric Ghevaert from @scicambridge.bsky.social.

More and register: milner.glueup.com/event/milner-seminars-focus-on-haematopoiesis-158139/
November 13, 2025 at 9:13 AM
natrevcancer.nature.com
ICYMI 🚨

In this month's #Focus issue on #AgeingandCancer, McAllister & colleagues discuss recent insights derived from age-resolved immunoprofiling of the TME and how ageing haematopoiesis affects immune cells and cancer progression.

#REVIEW 📖 👇
https://bit.ly/440R8...
November 11, 2025 at 4:01 PM
dev-journal.bsky.social
Anna said, "It’s a true honour to join this exceptional community of scientists as part of the Development editorial team. I share the journal’s commitment to excellence and integrity, and I’m eager to see more groundbreaking haematopoiesis research published in its pages."
November 11, 2025 at 10:47 AM
dev-journal.bsky.social
We are delighted to welcome Anna Bigas from @researchmar.bsky.social and Josep Carreras Leukemia Research Institute as a new Associate Editor at Development, handling papers on #haematopoiesis, #signalling and #cancer.

journals.biologists.com/dev/pages/ed...
Anna Bigas Associate Editor, Development Hospital de Mar Research Institute (HMRIB) and Josep Carreras Lukaemia Research Institute (IJC), Spain "I look forward to handling appers on developmental haematopoiesis and haematopoietic stem cells. I can also handle Notch signalling papers in different systems, as well as papers on cancer and leukaemia mechanisms." Key topics: development and disease, haematopoiesis, signalling, stem cells.
November 11, 2025 at 10:47 AM
milnerinst.bsky.social
📣 Milner Seminars: Focus on haematopoiesis🩸

Please join us on 19 November for the next instalment of our seminar series, with talks from Adam Wilkinson and Cédric Ghevaert from @scicambridge.bsky.social.

More and register: milner.glueup.com/event/milner-seminars-focus-on-haematopoiesis-158139/
November 6, 2025 at 8:10 AM
imperialimmuno.bsky.social
🚨 PhD Opportunity at @imperialimmuno.bsky.social!

Join Dr Deena Iskander’s lab to explore how bone marrow inflammation affects haematopoiesis in Diamond-Blackfan anaemia.

📍Hammersmith Campus
💰£22,780/year + Home Tuition

Apply now👇
www.findaphd.com/phds/project...
Investigating impact of bone marrow inflammation on haematopoiesis in Diamond-Blackfan anaemia syndrome at Imperial College London on FindAPhD.com
PhD Project - Investigating impact of bone marrow inflammation on haematopoiesis in Diamond-Blackfan anaemia syndrome at Imperial College London, listed on FindAPhD.com
www.findaphd.com
November 5, 2025 at 4:44 PM
zebrafishrock.bsky.social
Diamond-Blackfan Anemia (DBA) is a rare human disorder affecting red blood cell production, which often appears due to mutations in ribosomal protein, RPS19. To clarify its role in DBA, researchers made a rps19 knockout #zebrafish, which had impaired haematopoiesis. #KnowYourZDM 🧪
Figure 1 Zebrafish DBA models. Wild-type embryos show a high density of red blood cells (WT), whereas the blood production is drastically reduced in the rps19 knockdown (KD) and knockout (KO) embryos, as indicated by the absence of hemoglobin stained cells (lower panels). These embryos also display developmental deformities in head and tail regions (arrowheads). The abnormal phenotypes were rescued by injection of rps19 mRNA but not rescued by mRNA with patient type mutations in the knockdown embryos [14]. Credit to Uechi et al 2019
October 30, 2025 at 6:54 PM
milnerinst.bsky.social
📣 Milner Seminars: Focus on haematopoiesis🩸

Please join us on 19 November for the next instalment of our seminar series, with talks from Adam Wilkinson and Cédric Ghevaert from @scicambridge.bsky.social.

View talk titles and register: milner.glueup.com/ev...
October 30, 2025 at 8:00 AM
ericawood.bsky.social
Congratulations Dr Jasmine Singh on receiving the 2025 Haematology Society of Australia/NZ Albert Baikie Award, recognising the best Annual Scientific Meeting presentation by a new investigator, for "longitudinal assessment of the expansion of clonal haematopoiesis of indeterminate potential".
October 28, 2025 at 2:47 PM
ericawood.bsky.social
Out now in JAMA Cardiol: Clonal haematopoiesis of indeterminate potential (CHIP) not associated with higher risk of cardiovascular disease in ASPREE trial, but more clinically significant bleeding.

doi:10.1001/jamacardio.2025.3756
October 18, 2025 at 9:18 PM
nixassedes.bsky.social
Clonal Haematopoiesis of Indeterminate Potential: a Unifying Mechanism Linking Meta-inflammation and Cardiometabolic Diseases🔓
journals.physiology.org/doi/abs/10.1...
Clonal Haematopoiesis of Indeterminate Potential: a Unifying Mechanism Linking Meta-inflammation and Cardiometabolic Diseases | American Journal of Physiology-Heart and Circulatory Physiology | Americ...
Clonal haematopoiesis of indeterminate potential (CHIP) refers to the age-related expansion of haematopoietic stem cells bearing somatic mutations in the absence of overt haematological malignancy. Em...
journals.physiology.org
October 17, 2025 at 8:49 PM
nixassedes.bsky.social
Clonal haematopoiesis in cardiovascular disease: prognostic role and novel therapeutic target🔓
pmc.ncbi.nlm.nih.gov/articles/PMC...
Clonal haematopoiesis in cardiovascular disease: prognostic role and novel therapeutic target
Clonal haematopoiesis is the clonal expansion of blood stem cells with acquired mutations. Clonal haematopoiesis of indeterminate potential (CHIP), traditionally defined as clonal haematopoiesis drive...
pmc.ncbi.nlm.nih.gov
October 17, 2025 at 12:59 PM