Michael D. Wilson
@wilson-md.bsky.social
Senior Scientist, Program in Genetics and Genome Biology, Hospital for Sick Children; Associate Professor Dept. of Molecular Genetics, University of Toronto. Visiting Professor, University of Western Australia.
Reposted by Michael D. Wilson
♨️Live @ #BGEconnects:
Finished “EBP – How genomics is transforming understanding of biodiversity through reference genome production” by Harris Lewin, chair of @ebpgenome.bsky.social.
“Reference-quality genomes can now be produced at scale”, he says. “We need to work together to scale up.”
#BGE
Finished “EBP – How genomics is transforming understanding of biodiversity through reference genome production” by Harris Lewin, chair of @ebpgenome.bsky.social.
“Reference-quality genomes can now be produced at scale”, he says. “We need to work together to scale up.”
#BGE
September 30, 2025 at 12:42 PM
♨️Live @ #BGEconnects:
Finished “EBP – How genomics is transforming understanding of biodiversity through reference genome production” by Harris Lewin, chair of @ebpgenome.bsky.social.
“Reference-quality genomes can now be produced at scale”, he says. “We need to work together to scale up.”
#BGE
Finished “EBP – How genomics is transforming understanding of biodiversity through reference genome production” by Harris Lewin, chair of @ebpgenome.bsky.social.
“Reference-quality genomes can now be produced at scale”, he says. “We need to work together to scale up.”
#BGE
Reposted by Michael D. Wilson
Canada is ranked 1 in education, 3 in safety, 4 in justice, 4 in overall best country.
We are not a broken country. We have not suffered a lost decade.
Our existence is in the balance.
Vote.
We are not a broken country. We have not suffered a lost decade.
Our existence is in the balance.
Vote.
April 21, 2025 at 3:52 PM
Canada is ranked 1 in education, 3 in safety, 4 in justice, 4 in overall best country.
We are not a broken country. We have not suffered a lost decade.
Our existence is in the balance.
Vote.
We are not a broken country. We have not suffered a lost decade.
Our existence is in the balance.
Vote.
Reposted by Michael D. Wilson
PatchWorkPlot: simultaneous visualization of local alignments across multiple sequences arxiv.org/abs/2503.20766 🧬🖥️🧪 github.com/yana-safonov...
March 27, 2025 at 3:30 PM
PatchWorkPlot: simultaneous visualization of local alignments across multiple sequences arxiv.org/abs/2503.20766 🧬🖥️🧪 github.com/yana-safonov...
Reposted by Michael D. Wilson
4) Their definition of epigenetics is also somewhat awkward (see e.g. www.nature.com/articles/nrm...).
This is a very cool paper, but the science would shine brighter without the somewhat forced attempt to dress established knowledge as a new concept via awkward terminology.
This is a very cool paper, but the science would shine brighter without the somewhat forced attempt to dress established knowledge as a new concept via awkward terminology.
A user's guide to the ambiguous word 'epigenetics' - Nature Reviews Molecular Cell Biology
The term 'epigenetics' has multiple interpretations, so we need to be clear which definition we are using, argues John Greally.
www.nature.com
March 19, 2025 at 10:20 AM
4) Their definition of epigenetics is also somewhat awkward (see e.g. www.nature.com/articles/nrm...).
This is a very cool paper, but the science would shine brighter without the somewhat forced attempt to dress established knowledge as a new concept via awkward terminology.
This is a very cool paper, but the science would shine brighter without the somewhat forced attempt to dress established knowledge as a new concept via awkward terminology.
Reposted by Michael D. Wilson
Canada has existential choices to make in the Trump era. It had become complacent about its many virtues, and has had a sharp awakening, writes Michael Ignatieff.
www.prospectmagazine...
www.prospectmagazine...
As America retreats, Europe must step up
An unstable world order, divided between competing superpowers, will force all other nations to make tough choices
www.prospectmagazine.co.uk
March 16, 2025 at 11:23 AM
Canada has existential choices to make in the Trump era. It had become complacent about its many virtues, and has had a sharp awakening, writes Michael Ignatieff.
www.prospectmagazine...
www.prospectmagazine...
Reposted by Michael D. Wilson
This is incredible
Canadian artist Howie Tsui redesigned an old pinball machine into a simulation of a musket-ball rattling around a soldier's guts for an exhibition on the War of 1812. It's meant to demonstrate the way that repetition and concentration can inure a person to the horrors of war.
February 26, 2025 at 6:43 PM
This is incredible
Reposted by Michael D. Wilson
the united states no longer condemns russia’s invasion of ukraine. aligning the us with belarus, sudan, north korea and other failed states.
a reflection of changing policy and a wake up call for us allies.
a reflection of changing policy and a wake up call for us allies.
February 25, 2025 at 3:10 AM
the united states no longer condemns russia’s invasion of ukraine. aligning the us with belarus, sudan, north korea and other failed states.
a reflection of changing policy and a wake up call for us allies.
a reflection of changing policy and a wake up call for us allies.
Reposted by Michael D. Wilson
MW: Highlighting the importance of collaborative research to his own work - pointed out that a very fruitful project in his lab was spearheaded as a collaboration by a student who rotated in both labs and brought them together, the PIs now work together successfully on join projects #LorneGenome25
February 17, 2025 at 10:33 PM
MW: Highlighting the importance of collaborative research to his own work - pointed out that a very fruitful project in his lab was spearheaded as a collaboration by a student who rotated in both labs and brought them together, the PIs now work together successfully on join projects #LorneGenome25
Reposted by Michael D. Wilson
CDC source:
“We just had word that all our fellows and post doc staff are laid off effective immediately. The famous Epidemic Intelligence Service, aka the Disease Detectives, is no more. That’s 1260 staff.
They are calling this ‘Phase 1’.”
“We just had word that all our fellows and post doc staff are laid off effective immediately. The famous Epidemic Intelligence Service, aka the Disease Detectives, is no more. That’s 1260 staff.
They are calling this ‘Phase 1’.”
February 14, 2025 at 7:58 PM
CDC source:
“We just had word that all our fellows and post doc staff are laid off effective immediately. The famous Epidemic Intelligence Service, aka the Disease Detectives, is no more. That’s 1260 staff.
They are calling this ‘Phase 1’.”
“We just had word that all our fellows and post doc staff are laid off effective immediately. The famous Epidemic Intelligence Service, aka the Disease Detectives, is no more. That’s 1260 staff.
They are calling this ‘Phase 1’.”
"What I Believe" by Bertrand Russell is 100 yrs old and still relevant (www.gutenberg.org/ebooks/73782).
"The good life, as we conceive it, demands a multitude of social conditions, and cannot be realized without them. The good life, we said, is a life inspired by love and guided by knowledge."
"The good life, as we conceive it, demands a multitude of social conditions, and cannot be realized without them. The good life, we said, is a life inspired by love and guided by knowledge."
www.gutenberg.org
February 13, 2025 at 5:17 AM
"What I Believe" by Bertrand Russell is 100 yrs old and still relevant (www.gutenberg.org/ebooks/73782).
"The good life, as we conceive it, demands a multitude of social conditions, and cannot be realized without them. The good life, we said, is a life inspired by love and guided by knowledge."
"The good life, as we conceive it, demands a multitude of social conditions, and cannot be realized without them. The good life, we said, is a life inspired by love and guided by knowledge."
Reposted by Michael D. Wilson
You heard it here first folks, borders aren’t real, they’re just an artificial line someone drew.
This quote will 100% start one of my book chapters.
This quote will 100% start one of my book chapters.
The Canadian border is just a line somebody once drew on a map, but the Mexican border is a divine demarcation penned in golden light by the hands of angels.
February 10, 2025 at 1:06 PM
You heard it here first folks, borders aren’t real, they’re just an artificial line someone drew.
This quote will 100% start one of my book chapters.
This quote will 100% start one of my book chapters.
Reposted by Michael D. Wilson
You are making a big difference in standing up to tyranny. Your decision to cancel the family trip to the United States is freaking them out.
As Donald insults our nation, businesses are watching our tourism dollars dry up.
Boycott all trips to the United States.
www.thetravel.com/us-travel-as...
As Donald insults our nation, businesses are watching our tourism dollars dry up.
Boycott all trips to the United States.
www.thetravel.com/us-travel-as...
U.S. Travel Association Warns of Economic Tourism Disaster After Thousands of Canadian Tourists Cancel Trips in Protest
While Proposed Tariffs Against Canada Are Now Paused, Canadian Travel Agencies Already Witnessing Retaliation in Form of Canceled Trips
www.thetravel.com
February 9, 2025 at 7:09 PM
You are making a big difference in standing up to tyranny. Your decision to cancel the family trip to the United States is freaking them out.
As Donald insults our nation, businesses are watching our tourism dollars dry up.
Boycott all trips to the United States.
www.thetravel.com/us-travel-as...
As Donald insults our nation, businesses are watching our tourism dollars dry up.
Boycott all trips to the United States.
www.thetravel.com/us-travel-as...
Reposted by Michael D. Wilson
This is the most relevant article to NIH and research cuts I’ve seen.
Imagine if this was today , how many people would be saying “Why are we studying Gila Monsters and their impact on diabetes ? That’s wasted money !”
globalnews.ca/news/9793403...
Imagine if this was today , how many people would be saying “Why are we studying Gila Monsters and their impact on diabetes ? That’s wasted money !”
globalnews.ca/news/9793403...
How a Canadian scientist and a venomous lizard helped pave the way for Ozempic - National | Globalnews.ca
In 1984, Dr. Daniel Drucker, an endocrinologist from the University of Toronto, discovered a hormone that helped pave the way for popular diabetes drugs such as Ozempic.
globalnews.ca
February 9, 2025 at 9:58 PM
This is the most relevant article to NIH and research cuts I’ve seen.
Imagine if this was today , how many people would be saying “Why are we studying Gila Monsters and their impact on diabetes ? That’s wasted money !”
globalnews.ca/news/9793403...
Imagine if this was today , how many people would be saying “Why are we studying Gila Monsters and their impact on diabetes ? That’s wasted money !”
globalnews.ca/news/9793403...
Reposted by Michael D. Wilson
There's such a tone of sadness to the CBC reporting right now. Adrienne Arsenault says, “I feel like the whole country, all of us, are getting both a history lesson and a politics lesson and an economics lesson and a lesson in heartache.”
February 2, 2025 at 1:47 AM
There's such a tone of sadness to the CBC reporting right now. Adrienne Arsenault says, “I feel like the whole country, all of us, are getting both a history lesson and a politics lesson and an economics lesson and a lesson in heartache.”
Reposted by Michael D. Wilson
PubMed launched in 1996, but took time to take off as an Internet-enabled replacement. Now it's easy to forget how miserable the alternative was.
Thank you, National Library of Medicine, for keeping grad students where they belong: listening to true crime podcasts while pipetting.
Thank you, National Library of Medicine, for keeping grad students where they belong: listening to true crime podcasts while pipetting.
January 27, 2025 at 5:14 PM
PubMed launched in 1996, but took time to take off as an Internet-enabled replacement. Now it's easy to forget how miserable the alternative was.
Thank you, National Library of Medicine, for keeping grad students where they belong: listening to true crime podcasts while pipetting.
Thank you, National Library of Medicine, for keeping grad students where they belong: listening to true crime podcasts while pipetting.
Reposted by Michael D. Wilson
We found that copies of the LINE1 transposon are key “architects” of the nucleolar genome in human embryonic stem cells. This work brings together two facets of Barbara McClintock’s pioneering research: nucleolar organizer regions and transposable elements.
www.genesdev.org/cgi/doi/10.1...
www.genesdev.org/cgi/doi/10.1...
LINE1 elements at distal junctions of rDNA repeats regulate nucleolar organization in human embryonic stem cells
A biweekly scientific journal publishing high-quality research in molecular biology and genetics, cancer biology, biochemistry, and related fields
www.genesdev.org
January 2, 2025 at 8:36 PM
We found that copies of the LINE1 transposon are key “architects” of the nucleolar genome in human embryonic stem cells. This work brings together two facets of Barbara McClintock’s pioneering research: nucleolar organizer regions and transposable elements.
www.genesdev.org/cgi/doi/10.1...
www.genesdev.org/cgi/doi/10.1...
Reposted by Michael D. Wilson
My Tidyverse local synteny visualizer is up on GitHub: github.com/cxli233/Tidy...
GitHub page contains 2 example datasets, as well as step-by-step instruction & explanations on how it works. Details on required input data are discussed in the GitHub page. Let me know if you run into issues.
GitHub page contains 2 example datasets, as well as step-by-step instruction & explanations on how it works. Details on required input data are discussed in the GitHub page. Let me know if you run into issues.
December 12, 2024 at 2:03 AM
My Tidyverse local synteny visualizer is up on GitHub: github.com/cxli233/Tidy...
GitHub page contains 2 example datasets, as well as step-by-step instruction & explanations on how it works. Details on required input data are discussed in the GitHub page. Let me know if you run into issues.
GitHub page contains 2 example datasets, as well as step-by-step instruction & explanations on how it works. Details on required input data are discussed in the GitHub page. Let me know if you run into issues.
Excited to share our preprint describing a new naked mole rat reference genome! www.biorxiv.org/content/10.1... 1/9
An updated reference genome sequence and annotation reveals gene losses and gains underlying naked mole-rat biology
The naked mole-rat (NMR; Heterocephalus glaber ) is a eusocial subterranean rodent with a highly unusual set of physiological traits that has attracted great interest amongst the scientific community....
www.biorxiv.org
November 29, 2024 at 1:58 PM
Excited to share our preprint describing a new naked mole rat reference genome! www.biorxiv.org/content/10.1... 1/9
Reposted by Michael D. Wilson
BIOMORA24 is go!!! Going to be an amazing few days of science, meeting old friends & meeting people in the flesh who I’ve only seen online/read papers of/emailed!
November 28, 2024 at 8:45 AM
BIOMORA24 is go!!! Going to be an amazing few days of science, meeting old friends & meeting people in the flesh who I’ve only seen online/read papers of/emailed!