Tanya Gupta, PhD
@tgup-research.bsky.social
incoming assistant prof of psych & neuro at Santa Clara University Sept 2025 // neuro postdoc at UCLA // pfc, learning, timing, choice, computational modeling // proud Skinnerian behaviorist // desi
Pinned
Strange time to share good news, but I want my new Bluesky friends to know that the Gupta Lab will be starting at Santa Clara University where I will be starting as an assistant professor of neuroscience and psychology in the fall! 1/3
Reposted by Tanya Gupta, PhD
Thanks to Maryada (@giacomoi.bsky.social lab)! Due to component variability it is hard to set the weights across neuromorphic devices. Using our crosshomeostatic learning rule, that governs all four weight classes, we drove neuromorphic RNNs into balanced E/I regimes.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Stable recurrent dynamics in heterogeneous neuromorphic computing systems using excitatory and inhibitory plasticity - Nature Communications
Achieving the same robustness of biological networks in neuromorphic systems remains a challenge due to the variability in their analogue components. Here, the authors apply a biologically-plausible c...
www.nature.com
July 3, 2025 at 8:45 PM
Thanks to Maryada (@giacomoi.bsky.social lab)! Due to component variability it is hard to set the weights across neuromorphic devices. Using our crosshomeostatic learning rule, that governs all four weight classes, we drove neuromorphic RNNs into balanced E/I regimes.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Tanya Gupta, PhD
PREPRINT🚨Ever wonder how electrical⚡️ stimulation of the brain🧠modulates neuronal activity? Are you working with brain stim and variability makes you want to smash your pc and go to a mountain to grow tomatoes? Are you a family member or a friend who really appreciate me? 1/13
a man in a red shirt and black gloves is holding a box with the word success on it
ALT: a man in a red shirt and black gloves is holding a box with the word success on it
media.tenor.com
April 15, 2025 at 5:10 PM
PREPRINT🚨Ever wonder how electrical⚡️ stimulation of the brain🧠modulates neuronal activity? Are you working with brain stim and variability makes you want to smash your pc and go to a mountain to grow tomatoes? Are you a family member or a friend who really appreciate me? 1/13
Reposted by Tanya Gupta, PhD
🚨new paper alert
Blind mice use stereo olfaction, comparing smells between nostrils, to maintain a stable sense of direction. Blocking this ability disrupts their internal compass.
Kudos to @kasumbisa.bsky.social! Another cool chapter of the Trenholm-Peyrache collab😉
www.nature.com/articles/s41...
Blind mice use stereo olfaction, comparing smells between nostrils, to maintain a stable sense of direction. Blocking this ability disrupts their internal compass.
Kudos to @kasumbisa.bsky.social! Another cool chapter of the Trenholm-Peyrache collab😉
www.nature.com/articles/s41...
Stereo olfaction underlies stable coding of head direction in blind mice - Nature Communications
Stereo olfaction involves comparing odor differences between the two nostrils. Here, using neuronal recordings and a behavioral test, the authors demonstrate that blind mice use stereo olfaction to fo...
www.nature.com
April 14, 2025 at 6:37 PM
🚨new paper alert
Blind mice use stereo olfaction, comparing smells between nostrils, to maintain a stable sense of direction. Blocking this ability disrupts their internal compass.
Kudos to @kasumbisa.bsky.social! Another cool chapter of the Trenholm-Peyrache collab😉
www.nature.com/articles/s41...
Blind mice use stereo olfaction, comparing smells between nostrils, to maintain a stable sense of direction. Blocking this ability disrupts their internal compass.
Kudos to @kasumbisa.bsky.social! Another cool chapter of the Trenholm-Peyrache collab😉
www.nature.com/articles/s41...
Reposted by Tanya Gupta, PhD
Keep pushing back. Every win matters.
www.washingtonpost.com/nation/2025/...
www.washingtonpost.com/nation/2025/...
Anger, then relief after Pentagon restores Navajo code talker webpages
Navajo Nation leaders and families of code talkers had pushed back against the removals.
www.washingtonpost.com
April 10, 2025 at 1:44 PM
Keep pushing back. Every win matters.
www.washingtonpost.com/nation/2025/...
www.washingtonpost.com/nation/2025/...
Reposted by Tanya Gupta, PhD
The GRFP is an extremely cost-effective way to nurture young talent in science. Cuts are short-sighted and cruel, but that's the aim of this administration, isn't it? 🧪💔
NSF slashes prestigious PhD fellowship awards by half
US National Science Foundation announces lowest number of Graduate Research Fellowship Programme recipients in 15 years.
www.nature.com
April 9, 2025 at 5:14 AM
The GRFP is an extremely cost-effective way to nurture young talent in science. Cuts are short-sighted and cruel, but that's the aim of this administration, isn't it? 🧪💔
Reposted by Tanya Gupta, PhD
Yesterday's announcement canceling MARC, PREP, IMSD & IRACDA finally broke me. Spent most of the morning in my office crying. I think I'd been clinging to a glimmer of hope, but as an IRACDA alum,watching the the scale of loss for young scientists was heartbreaking. 🧪
www.nytimes.com/2025/04/03/o...
www.nytimes.com/2025/04/03/o...
Opinion | The Uncertain Fate of the Young American Scientist
Young researchers are choosing between staying in science and staying in the United States.
www.nytimes.com
April 3, 2025 at 7:35 PM
Yesterday's announcement canceling MARC, PREP, IMSD & IRACDA finally broke me. Spent most of the morning in my office crying. I think I'd been clinging to a glimmer of hope, but as an IRACDA alum,watching the the scale of loss for young scientists was heartbreaking. 🧪
www.nytimes.com/2025/04/03/o...
www.nytimes.com/2025/04/03/o...
Reposted by Tanya Gupta, PhD
Averaging over time hides what a neuron actually sees, what it actually gets to compute with, writes @markdhumphries.bsky.social.
#neuroskyence
www.thetransmitter.org/neural-codin...
#neuroskyence
www.thetransmitter.org/neural-codin...
Averaging is a convenient fiction of neuroscience
But neurons don’t take averages. This ubiquitous practice hides from us how the brain really works.
www.thetransmitter.org
March 26, 2025 at 6:14 PM
Averaging over time hides what a neuron actually sees, what it actually gets to compute with, writes @markdhumphries.bsky.social.
#neuroskyence
www.thetransmitter.org/neural-codin...
#neuroskyence
www.thetransmitter.org/neural-codin...
Leaving this year's March Madness bracket up to ✨spurious correlations✨ 🏀
March 20, 2025 at 5:56 PM
Leaving this year's March Madness bracket up to ✨spurious correlations✨ 🏀
Reposted by Tanya Gupta, PhD
We had a lot of fun featuring beautiful new work from Laura DeNardo's lab in which they revealed prefrontal ensemble activity transformations underlying rapid threat avoidance learning! www.cell.com/current-biol...
Original paper published in Current Biology: www.cell.com/current-biol...
Original paper published in Current Biology: www.cell.com/current-biol...
Threat learning: Avoiding danger in the first place
While the ability of an animal to rapidly learn to detect and avoid threats is critical
for survival, previous research has focused on post-learning time periods. A new computational
study now reveals...
www.cell.com
March 13, 2025 at 6:53 PM
We had a lot of fun featuring beautiful new work from Laura DeNardo's lab in which they revealed prefrontal ensemble activity transformations underlying rapid threat avoidance learning! www.cell.com/current-biol...
Original paper published in Current Biology: www.cell.com/current-biol...
Original paper published in Current Biology: www.cell.com/current-biol...
Reposted by Tanya Gupta, PhD
Endocrine researchers, you may have think you're safe because you don't do 'trans' research, but attacks on trans research is an attack on us all.
www.whitehouse.gov/articles/202...
www.whitehouse.gov/articles/202...
Yes, Biden Spent Millions on Transgender Animal Experiments
Last night, President Donald J. Trump highlighted many of the egregious examples of waste, fraud, and abuse funded by American taxpayers, including $8
www.whitehouse.gov
March 5, 2025 at 10:19 PM
Endocrine researchers, you may have think you're safe because you don't do 'trans' research, but attacks on trans research is an attack on us all.
www.whitehouse.gov/articles/202...
www.whitehouse.gov/articles/202...
Reposted by Tanya Gupta, PhD
Exclusive: NIH appears to archive policy requiring female animals in studies www.thetransmitter.org/policy/exclu...
Exclusive: NIH appears to archive policy requiring female animals in studies
Such a shift would “put us back in the dark ages in terms of our science,” says neuroscientist Anne Murphy, who helped to formulate the original policy.
www.thetransmitter.org
February 24, 2025 at 10:28 PM
Exclusive: NIH appears to archive policy requiring female animals in studies www.thetransmitter.org/policy/exclu...
Strange time to share good news, but I want my new Bluesky friends to know that the Gupta Lab will be starting at Santa Clara University where I will be starting as an assistant professor of neuroscience and psychology in the fall! 1/3
February 24, 2025 at 8:51 PM
Strange time to share good news, but I want my new Bluesky friends to know that the Gupta Lab will be starting at Santa Clara University where I will be starting as an assistant professor of neuroscience and psychology in the fall! 1/3
Reposted by Tanya Gupta, PhD
Many neuroscience students are steeped in an experiment-first style of thinking that leads to “random walk science.” Let’s not forget how theory can guide experiments towards deeper insights, writes @gershbrain.bsky.social.
#neuroskyence
www.thetransmitter.org/theoretical-...
#neuroskyence
www.thetransmitter.org/theoretical-...
Breaking the barrier between theorists and experimentalists
Many neuroscience students are steeped in an experiment-first style of thinking. Let’s not forget how theory can guide experiments.
www.thetransmitter.org
February 24, 2025 at 2:55 PM
Many neuroscience students are steeped in an experiment-first style of thinking that leads to “random walk science.” Let’s not forget how theory can guide experiments towards deeper insights, writes @gershbrain.bsky.social.
#neuroskyence
www.thetransmitter.org/theoretical-...
#neuroskyence
www.thetransmitter.org/theoretical-...
Reposted by Tanya Gupta, PhD
It’s been hard lately to focus on doing my job as a postdoc, which is under daily threat at this point. But we are persisting. Out now: “Dissociating the incubation of appetitive and consummatory behavior in a model of oral cocaine self-administration”. Very thankful to all who helped get this done!
www.biorxiv.org
February 13, 2025 at 10:12 PM
It’s been hard lately to focus on doing my job as a postdoc, which is under daily threat at this point. But we are persisting. Out now: “Dissociating the incubation of appetitive and consummatory behavior in a model of oral cocaine self-administration”. Very thankful to all who helped get this done!
Concerned that I may have to title my next NIH grant "The Benefits of Extremely Traditional Family Values on Brain Health in Mice" if I want any funding 😬
January 23, 2025 at 1:52 AM
Concerned that I may have to title my next NIH grant "The Benefits of Extremely Traditional Family Values on Brain Health in Mice" if I want any funding 😬
Reposted by Tanya Gupta, PhD
Always 👏 look 👏 at 👏 the 👏 raw 👏 data
January 17, 2025 at 6:42 PM
Always 👏 look 👏 at 👏 the 👏 raw 👏 data
Reposted by Tanya Gupta, PhD
Reposted by Tanya Gupta, PhD
This @naturemethods.bsky.social paper www.nature.com/articles/s41... on guidelines for publishing images is awesome! I have folks at @mbfbioscience.bsky.social reading it so that we can help our customers. #microscopy #Neuroscience #imaging #FAIR
Community-developed checklists for publishing images and image analyses - Nature Methods
Community-developed checklists offer best-practice guidance for biologists preparing light microscopy images and describing image analyses for publications.
www.nature.com
January 16, 2025 at 10:57 PM
This @naturemethods.bsky.social paper www.nature.com/articles/s41... on guidelines for publishing images is awesome! I have folks at @mbfbioscience.bsky.social reading it so that we can help our customers. #microscopy #Neuroscience #imaging #FAIR
Reposted by Tanya Gupta, PhD
This article shows that "non-responsive" neurons can still add to the Fisher Info about object location in the midbrain of weakly electric fish:
www.jneurosci.org/content/45/3...
Brings me back to one of my usual bugbears in #neuroscience, i.e. don't judge a cell's function by its tuning curve!
🧪
www.jneurosci.org/content/45/3...
Brings me back to one of my usual bugbears in #neuroscience, i.e. don't judge a cell's function by its tuning curve!
🧪
Nonresponsive Neurons Improve Population Coding of Object Location
Understanding how heterogeneous neural populations represent sensory input to give rise to behavior remains a central problem in systems neuroscience. Here we investigated how midbrain neurons within ...
www.jneurosci.org
January 15, 2025 at 7:04 PM
This article shows that "non-responsive" neurons can still add to the Fisher Info about object location in the midbrain of weakly electric fish:
www.jneurosci.org/content/45/3...
Brings me back to one of my usual bugbears in #neuroscience, i.e. don't judge a cell's function by its tuning curve!
🧪
www.jneurosci.org/content/45/3...
Brings me back to one of my usual bugbears in #neuroscience, i.e. don't judge a cell's function by its tuning curve!
🧪
Reposted by Tanya Gupta, PhD
Reposted by Tanya Gupta, PhD
Hippocampus and orbital frontal cortex synchronise to make the right choice given the context:
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Context-dependent decision-making in the primate hippocampal–prefrontal circuit - Nature Neuroscience
The brain uses different valuation schemes across contexts. Elston and Wallis show this is supported by hippocampal encoding of context that is broadcast to prefrontal value subcircuits via theta sync...
www.nature.com
January 8, 2025 at 12:41 PM
Hippocampus and orbital frontal cortex synchronise to make the right choice given the context:
www.nature.com/articles/s41...
www.nature.com/articles/s41...
one of my more hauntingly beautiful python errors.
January 4, 2025 at 10:25 PM
one of my more hauntingly beautiful python errors.
Reposted by Tanya Gupta, PhD
Vibrational fiber photometry, developed by the Pisanello lab, enables Raman spectroscopy in the mouse brain with low impact, owing to the use of tapered fibers.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Vibrational fiber photometry: label-free and reporter-free minimally invasive Raman spectroscopy deep in the mouse brain - Nature Methods
Vibrational fiber photometry enables Raman spectroscopy in the mouse brain with low impact, owing to the use of tapered fibers.
www.nature.com
January 3, 2025 at 4:04 PM
Vibrational fiber photometry, developed by the Pisanello lab, enables Raman spectroscopy in the mouse brain with low impact, owing to the use of tapered fibers.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Tanya Gupta, PhD
Inferring context-dependent computations through linear approximations of prefrontal cortex dynamics
www.science.org/doi/10.1126/...
#neuroscience
www.science.org/doi/10.1126/...
#neuroscience
Inferring context-dependent computations through linear approximations of prefrontal cortex dynamics
PFC neural responses during contextual decision-making are consistent with both recurrent and input-driven flexible computations.
www.science.org
January 3, 2025 at 7:00 PM
Inferring context-dependent computations through linear approximations of prefrontal cortex dynamics
www.science.org/doi/10.1126/...
#neuroscience
www.science.org/doi/10.1126/...
#neuroscience