Nathan J. O'Connor, PhD, MS
@nateoconnor.bsky.social
I love food, dogs, science, and good people. #neuroscience #cellbio
I'm a scientist at MBF Bioscience and views expressed are my own.
I'm a scientist at MBF Bioscience and views expressed are my own.
Proud to be a part of this transformative work from the Tomer Lab & @mbfbioscience.bsky.social 🔬
HySIL & SCOPE are the framework that power the new SLICE light-sheet microscope. 🚀
Submicron resolution, multi-immersion, and affordability:
www.biorxiv.org/content/10.1...
#Microscopy #LightSheet
HySIL & SCOPE are the framework that power the new SLICE light-sheet microscope. 🚀
Submicron resolution, multi-immersion, and affordability:
www.biorxiv.org/content/10.1...
#Microscopy #LightSheet
Hybrid Solid-Liquid Optics Enable Scalable, High-Resolution, Multi-Immersion Light-Sheet Microscopy
Modern biology increasingly depends on data-driven discovery, requiring scalable and affordable high-content 3D imaging across molecular to organ scales. Although tissue clearing, expansion microscopy...
www.biorxiv.org
November 19, 2025 at 8:09 PM
Proud to be a part of this transformative work from the Tomer Lab & @mbfbioscience.bsky.social 🔬
HySIL & SCOPE are the framework that power the new SLICE light-sheet microscope. 🚀
Submicron resolution, multi-immersion, and affordability:
www.biorxiv.org/content/10.1...
#Microscopy #LightSheet
HySIL & SCOPE are the framework that power the new SLICE light-sheet microscope. 🚀
Submicron resolution, multi-immersion, and affordability:
www.biorxiv.org/content/10.1...
#Microscopy #LightSheet
Big data in microscopy shouldn't be a bottleneck.
I started Arnas Technologies arnastech.com to solve exactly that. We build custom #AI workflows to automate analysis for #lightsheet, #microscopy, and #OMICS data.
#BioTech #DataScience #ImageAnalysis #BioImageAnalysis
I started Arnas Technologies arnastech.com to solve exactly that. We build custom #AI workflows to automate analysis for #lightsheet, #microscopy, and #OMICS data.
#BioTech #DataScience #ImageAnalysis #BioImageAnalysis
November 19, 2025 at 7:16 PM
Big data in microscopy shouldn't be a bottleneck.
I started Arnas Technologies arnastech.com to solve exactly that. We build custom #AI workflows to automate analysis for #lightsheet, #microscopy, and #OMICS data.
#BioTech #DataScience #ImageAnalysis #BioImageAnalysis
I started Arnas Technologies arnastech.com to solve exactly that. We build custom #AI workflows to automate analysis for #lightsheet, #microscopy, and #OMICS data.
#BioTech #DataScience #ImageAnalysis #BioImageAnalysis
Reposted by Nathan J. O'Connor, PhD, MS
🎨 You’re invited to an Evening of Art and Ideas!
Experience science and creativity over appetizers, drinks, and the exhibition Umwelt: Phenomenal Worlds, exploring perception and consciousness.
📍 UC San Diego Park & Market
🗓️ Sun, Nov 16 | 6–9 PM
✨ We hope to see you there!
Experience science and creativity over appetizers, drinks, and the exhibition Umwelt: Phenomenal Worlds, exploring perception and consciousness.
📍 UC San Diego Park & Market
🗓️ Sun, Nov 16 | 6–9 PM
✨ We hope to see you there!
November 11, 2025 at 8:19 PM
🎨 You’re invited to an Evening of Art and Ideas!
Experience science and creativity over appetizers, drinks, and the exhibition Umwelt: Phenomenal Worlds, exploring perception and consciousness.
📍 UC San Diego Park & Market
🗓️ Sun, Nov 16 | 6–9 PM
✨ We hope to see you there!
Experience science and creativity over appetizers, drinks, and the exhibition Umwelt: Phenomenal Worlds, exploring perception and consciousness.
📍 UC San Diego Park & Market
🗓️ Sun, Nov 16 | 6–9 PM
✨ We hope to see you there!
Reposted by Nathan J. O'Connor, PhD, MS
First real-time human embryo implantation recorded (in 2D and 3D). Time lapse video of 2 embryos (200 μm apart) implanting in the 3D platform
science.org/doi/10.1126/...
science.org/doi/10.1126/...
August 15, 2025 at 7:39 PM
First real-time human embryo implantation recorded (in 2D and 3D). Time lapse video of 2 embryos (200 μm apart) implanting in the 3D platform
science.org/doi/10.1126/...
science.org/doi/10.1126/...
Lightsheet microscopy produces terabytes of image data quickly—creating storage, transfer, and analysis bottlenecks. In my work, I’ve found smart compression strategies to be essential. Here are some of my observations:
figshare.com/articles/pre...
#microscopy @mbfbioscience.bsky.social
figshare.com/articles/pre...
#microscopy @mbfbioscience.bsky.social
A Practical Guide to Selecting Compression Levels for 3D Light Sheet Fluorescent Microscopy Data
A white paper outlining practical strategies for managing the large data volumes generated by 3D light sheet fluorescence microscopy, with a focus on selecting compression levels that balance file siz...
figshare.com
August 13, 2025 at 7:41 PM
Lightsheet microscopy produces terabytes of image data quickly—creating storage, transfer, and analysis bottlenecks. In my work, I’ve found smart compression strategies to be essential. Here are some of my observations:
figshare.com/articles/pre...
#microscopy @mbfbioscience.bsky.social
figshare.com/articles/pre...
#microscopy @mbfbioscience.bsky.social
Checkout this webinar (8-6-25; 12pm EDT) on the SLICE light sheet microscope from @MBFBioscience! This high performance system is the size of a microwave and costs less than most confocals. I've loved working on this democratizing leap in #microscopy. #goodStuff #neuroscience
July 29, 2025 at 9:49 PM
Checkout this webinar (8-6-25; 12pm EDT) on the SLICE light sheet microscope from @MBFBioscience! This high performance system is the size of a microwave and costs less than most confocals. I've loved working on this democratizing leap in #microscopy. #goodStuff #neuroscience
Checkout this webinar (8-6-25; 12pm EDT) on the SLICE light sheet microscope from @mbfbioscience.bsky.social! This high performance system is the size of a microwave and costs less than most confocals. I've loved working on this democratizing scientific leap in #microscopy #goodStuff #neuroscience
Join us for a free webinar featuring SLICE 🔬 — the high-performance, scalable light sheet microscope.
With Dr. Tomer @rtomer.bsky.social (Columbia) + live Q&A!
📅 Aug 6, 12 PM ET
🔗 Register: us06web.zoom.us/webinar/regi...
With Dr. Tomer @rtomer.bsky.social (Columbia) + live Q&A!
📅 Aug 6, 12 PM ET
🔗 Register: us06web.zoom.us/webinar/regi...
July 29, 2025 at 9:37 PM
Checkout this webinar (8-6-25; 12pm EDT) on the SLICE light sheet microscope from @mbfbioscience.bsky.social! This high performance system is the size of a microwave and costs less than most confocals. I've loved working on this democratizing scientific leap in #microscopy #goodStuff #neuroscience
My #capybara friend is helping me register brains to Dr. Kim's devCCF (kimlab.io/brain-map/De...) atlas based on the CCF mouse brain atlas from the @alleninstitute.org. @mbfbioscience.bsky.social I'm, of course, using NeuroInfo for registration and cell counting :) #neuroScience
June 16, 2025 at 10:35 PM
My #capybara friend is helping me register brains to Dr. Kim's devCCF (kimlab.io/brain-map/De...) atlas based on the CCF mouse brain atlas from the @alleninstitute.org. @mbfbioscience.bsky.social I'm, of course, using NeuroInfo for registration and cell counting :) #neuroScience
Chunky black bean corn #salsa to go with quesadillas made from leftover lean grilled to sirloin. #easycooking
June 4, 2025 at 10:49 PM
Chunky black bean corn #salsa to go with quesadillas made from leftover lean grilled to sirloin. #easycooking
Our abstract for #SfN25 is in! #neuroscience @mbfbioscience.bsky.social #science #brains #connectomics #microscopy
June 4, 2025 at 6:40 PM
Our abstract for #SfN25 is in! #neuroscience @mbfbioscience.bsky.social #science #brains #connectomics #microscopy
Protect the future of biomedical research!
www.mbfbioscience.com/news/2025/03...
@mbfbioscience.bsky.social @alleninstitute.bsky.social #science #neuroscience @mcuban.bsky.social
www.mbfbioscience.com/news/2025/03...
@mbfbioscience.bsky.social @alleninstitute.bsky.social #science #neuroscience @mcuban.bsky.social
Protecting the Future of Biomedical Research: A Call to Defend NIH Funding
Join us to defend science—write, call, and speak up. Biomedical research must be protected; the cost of inaction is too high for human lives.
www.mbfbioscience.com
March 6, 2025 at 8:35 PM
Protect the future of biomedical research!
www.mbfbioscience.com/news/2025/03...
@mbfbioscience.bsky.social @alleninstitute.bsky.social #science #neuroscience @mcuban.bsky.social
www.mbfbioscience.com/news/2025/03...
@mbfbioscience.bsky.social @alleninstitute.bsky.social #science #neuroscience @mcuban.bsky.social
Reposted by Nathan J. O'Connor, PhD, MS
#BrainAwarenessWeek is almost here! 🧠✨ We're considering hosting some Bluesky chats to bring the #Neuroskyence community together. Would this be something you would join in on? What would you ask the community?
February 20, 2025 at 10:48 PM
#BrainAwarenessWeek is almost here! 🧠✨ We're considering hosting some Bluesky chats to bring the #Neuroskyence community together. Would this be something you would join in on? What would you ask the community?
February 19, 2025 at 11:09 PM
Reposted by Nathan J. O'Connor, PhD, MS
Portuguese editorial cartoonist Zez Vaz reaches back to Tiananmen Square to call on American defiance.
February 15, 2025 at 1:43 PM
Portuguese editorial cartoonist Zez Vaz reaches back to Tiananmen Square to call on American defiance.
Stuart got us these bands for #valentinesday. Solid as metal together. No matter what happens in these crazy times, nothing will break us. #LGBT #civilrights
February 15, 2025 at 9:23 PM
Stuart got us these bands for #valentinesday. Solid as metal together. No matter what happens in these crazy times, nothing will break us. #LGBT #civilrights
Reposted by Nathan J. O'Connor, PhD, MS
In this month's Editorial, we discuss best practices for reporting methods so that they can be reused by other labs. Read it here!
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reporting methods for reusability - Nature Methods
Proper methods reporting is crucial for transparency, but ensuring method reusability by other labs takes a bit of extra effort. Here we discuss best practices for reporting methods so that they can b...
www.nature.com
February 11, 2025 at 6:45 PM
In this month's Editorial, we discuss best practices for reporting methods so that they can be reused by other labs. Read it here!
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Nathan J. O'Connor, PhD, MS
Why does the world's richest man want to gut the CFPB?
Because it would shield him from having to follow financial laws to keep customers' money safe — and give him access to confidential records about his competitors.
Follow the money.
Because it would shield him from having to follow financial laws to keep customers' money safe — and give him access to confidential records about his competitors.
Follow the money.
February 10, 2025 at 5:26 PM
Why does the world's richest man want to gut the CFPB?
Because it would shield him from having to follow financial laws to keep customers' money safe — and give him access to confidential records about his competitors.
Follow the money.
Because it would shield him from having to follow financial laws to keep customers' money safe — and give him access to confidential records about his competitors.
Follow the money.
I know it's an awesome day for celebration (#superbowl), but please don't #DrinkAndDrive. I've lost a brother and a brother-in-law to drunk drivers. Ubers and taxis are so easy to get. www.nhtsa.gov/risky-drivin...
Drunk Driving | NHTSA
Get resources on ways to prevent drunk driving and alcohol-impaired crashes along with national drunk driving statistics and facts.
www.nhtsa.gov
February 9, 2025 at 10:51 PM
I know it's an awesome day for celebration (#superbowl), but please don't #DrinkAndDrive. I've lost a brother and a brother-in-law to drunk drivers. Ubers and taxis are so easy to get. www.nhtsa.gov/risky-drivin...
Reposted by Nathan J. O'Connor, PhD, MS
JD Vance, a Yale Law graduate, doesn't understand Marbury v. Madison, the most famous case in Constitutional law, which established judicial review of the other two branches of government.
February 9, 2025 at 8:22 PM
JD Vance, a Yale Law graduate, doesn't understand Marbury v. Madison, the most famous case in Constitutional law, which established judicial review of the other two branches of government.
So much for the #GOP being the party of "law and order"... and this is from Forbes. #JDVance www.forbes.com/sites/alison...
JD Vance Suggests Judges ‘Aren't Allowed’ To Control Trump After Courts Block His Policies
A slew of court rulings in recent weeks have hampered the Trump administration’s moves on issues like birthright citizenship and shutting down USAID.
www.forbes.com
February 9, 2025 at 8:07 PM
So much for the #GOP being the party of "law and order"... and this is from Forbes. #JDVance www.forbes.com/sites/alison...
There seems to be a growing body of research on the #brain and #microplastics. scholar.google.com/scholar?hl=e...
This is an interesting article from that search: www.science.org/doi/abs/10.1...
#neuroscience #microscopy
This is an interesting article from that search: www.science.org/doi/abs/10.1...
#neuroscience #microscopy
Microplastics in the bloodstream can induce cerebral thrombosis by causing cell obstruction and lead to neurobehavioral abnormalities
Microplastics get in the blood and are eaten by immune cells, leading to cell obstruction and cerebral thrombosis.
www.science.org
February 7, 2025 at 10:36 PM
There seems to be a growing body of research on the #brain and #microplastics. scholar.google.com/scholar?hl=e...
This is an interesting article from that search: www.science.org/doi/abs/10.1...
#neuroscience #microscopy
This is an interesting article from that search: www.science.org/doi/abs/10.1...
#neuroscience #microscopy
This is from #Albany #NY today. I was born in Albany county a couple of cities over ( #Cohoes ). It's heartbreaking to see this in my normally calm and tolerant home area. Believe everything #Trump and his supporters say. They are completely sincere. #LGBT
www.youtube.com/shorts/8uv2J...
www.youtube.com/shorts/8uv2J...
February 5, 2025
YouTube video by Tammie Eller
www.youtube.com
February 6, 2025 at 2:15 AM
Reposted by Nathan J. O'Connor, PhD, MS
Interested in presenting a talk or poster at the Open Science in Undergrad Education Symposium? Here are some important deadlines!
🎙️ Feb. 22 - Abstracts for 20-minute talks
🖼️ April 1 - Abstracts for posters
Learn more and submit your abstract:
alleninstitute.org/events/opens...
🧬 #EduSky
🎙️ Feb. 22 - Abstracts for 20-minute talks
🖼️ April 1 - Abstracts for posters
Learn more and submit your abstract:
alleninstitute.org/events/opens...
🧬 #EduSky
Open Science in Undergraduate Education Symposium
Join the Allen Institute for the Open Science in Undergraduate Education Symposium in Seattle, Washington next June. This interactive symposium brings together those working to integrate openly availa...
alleninstitute.org
February 4, 2025 at 11:09 PM
Interested in presenting a talk or poster at the Open Science in Undergrad Education Symposium? Here are some important deadlines!
🎙️ Feb. 22 - Abstracts for 20-minute talks
🖼️ April 1 - Abstracts for posters
Learn more and submit your abstract:
alleninstitute.org/events/opens...
🧬 #EduSky
🎙️ Feb. 22 - Abstracts for 20-minute talks
🖼️ April 1 - Abstracts for posters
Learn more and submit your abstract:
alleninstitute.org/events/opens...
🧬 #EduSky