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mccullylab.bsky.social
Michelle McCully
@mccullylab.bsky.social
1.2K followers 300 following 120 posts
The McCully Lab at Santa Clara University studies the structure, dynamics, and function of proteins towards designing better ones.
sites.google.com/site/mccullylabscu

BS WashU | PhD UW | Postdoc UCSF | Assoc prof SCU
Acamama, PUI, family biking, Bay Area
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mccullylab.bsky.social
Michelle McCully @mccullylab.bsky.social · Nov 17
I'm working on a starter pack (who isn't?) of faculty at Santa Clara University. Reply if you want on (or off!)
go.bsky.app/FwJDjZC

#SantaClaraUniversity #SCU #GoBroncos
Reposted by Michelle McCully
altcdc.altgov.info
Do what you can.

❤️‍🩹Take care of yourself.
🫂Take care of each other.
☎️Call 5calls.org
🧑‍💻Write democracy.io#!/thanks
🚫Boycott ICE: www.boycottcitizens.org/ice
✊Support MN: www.standwithminnesota.com
Stand With Minnesota Donation Directory
Stand With Minnesota is a hub for supporting, learning, and taking action to support Minnesotans impacted by ICE and federal enforcement.
www.standwithminnesota.com
January 26, 2026 at 12:45 AM
Reposted by Michelle McCully
admirablewomen.bsky.social
Jane Richardson was born #OTD in 1941

+ Developed the Richardson (ribbon) diagram to represent proteins' 3D structure (becoming a standard representation for protein structures)
+ MacArthur Fellow, 1985
+ Elected, Nat'l Academy of Sciences, 1991
+ President, Biophysical Society, 2012

#WomenInSTEM
Vibrant color portrait of Jane S. Richardson, the visionary biophysicist and artist who revolutionized structural biology with her invention of ribbon diagrams. She gazes warmly at the camera with a bright, knowing smile that radiates quiet brilliance and decades of curiosity. Her silver-blonde hair woven with gentle waves. Large, elegant dangling earrings catch the light, and she wears a richly patterned brown blouse embroidered with intricate turquoise paisley motifs and delicate beadwork that echoes the molecular elegance she has spent her life depicting. Behind her floats a luminous, dreamlike backdrop of glowing molecular structures--interlocking hexagonal and ribbon-like forms in electric blues, teals, and greens--blending science and art in a single, living canvas. Hand-drawn and hand-colored (by Jane Richardson) scientific artwork known as a Richardson ribbon diagram (or “ribbon model”), one of the iconic visual inventions of Jane Richardson that transformed the way we see and understand protein structures. A graceful, three-dimensional tangle of protein backbone ribbons twists and spirals through space, rendered in soft pencil lines and luminous watercolor hues. Smooth golden-brown coils represent α-helices that curl like elegant ribbons, while broad teal-green arrows trace the flat, pleated strands of β-sheets slicing through the molecule with directional purpose. Thin, looping golden threads connect the secondary structures, creating a delicate, almost dance-like choreography of biology’s hidden architecture. The entire form is framed by a simple olive-green mat and dark border, giving the drawing the quiet dignity of both fine art and precise scientific illustration—a timeless bridge between molecular reality and human imagination.
January 26, 2026 at 12:06 AM
Reposted by Michelle McCully
lauragmitchell.com
We've raised a lot of money for my school community neighbors.

And I predict all of it will be depleted by the end of this week.

If you're in a position to donate, please help: paypal.me/lyndalepto

(donations are tax deductible)

3/3
Mutual aid fundraiser poster for Lyndale Community School
January 26, 2026 at 1:16 AM
Reposted by Michelle McCully
keatinglab.bsky.social
Here’s a preprint from the Keating Lab: www.biorxiv.org/content/10.6.... Foster Birnbaum and Amy E. Keating demonstrate that sequence design models, such as ProteinMPNN, are limited because they were trained only on native sequences.
www.biorxiv.org
January 18, 2026 at 6:23 AM
Reposted by Michelle McCully
brenttoderian.bsky.social
“We shouldn’t be aiming to nudge a few % points in public opinion. Our goal should be to make freedom of mobility so compelling that people demand it. Help people visualize & demand a future where kids can bike to school, seniors can walk to stores, couples can bike to dinner.” @usa.streetsblog.org
Opinion: Stop Asking If People Want to Ride Bikes — Streetsblog USA
"We shouldn’t be aiming to nudge a few percentage points in public opinion. Our goal should be to make freedom of mobility so compelling that people demand it."
usa.streetsblog.org
January 15, 2026 at 3:21 AM
mccullylab.bsky.social
Here for the right reasons
altmetric.com Altmetric @altmetric.com · 21d
THREAD

The first full year of tracking research on @bsky.app

Hi, we are Altmetric, and we track how research is communicated across the web.

We now have one full calendar year of Bluesky research data and thought we'd have a looksie.
My name is Jeff meme with Altmetric replaced. Channing Tatum with his clothes on.
January 10, 2026 at 5:20 AM
Reposted by Michelle McCully
carolynbertozzi.bskyverified.social
Exciting new work from @aliceyting.bsky.social and coworkers @stanfordbiosci.bsky.social @stanfordmedicine.bsky.social

www.science.org/doi/10.1126/...
Computational design of conformation-biasing mutations to alter protein functions
Conformational biasing (CB) is a rapid and streamlined computational method that uses contrastive scoring by inverse folding models to predict protein variants biased toward desired conformational sta...
www.science.org
January 9, 2026 at 5:47 AM
Reposted by Michelle McCully
pleunipennings.bsky.social
I have started updating my website because I am no longer at San Francisco State.
I also wrote on my website landing page that I am writing a book about my favorite topic: evolution of drug resistance. That's my biggest goal for the year! pleunipennings.wordpress.com
This is a drawing about the book I want to write. Alt text: Drawing with on the left a person with a megaphone and the text: “DOOM NEWS Superbugs on the rise, soon all bacteria resistant!?” And on the right a person with heart-shaped glasses and the text: “NEWS Evolution-proof drug discovered”. In the middle it says: “The news can be extreme. Better news about drug resistance. Evolution, data and how we are winning the fights against drug resistance”
January 6, 2026 at 7:57 PM
Reposted by Michelle McCully
petridishes.bsky.social
here’s hoping 2026 is just one year
January 1, 2026 at 4:02 AM
Reposted by Michelle McCully
gregggonsalves.bsky.social
#JohnsHopkins @ucsfmedicine.bsky.social and @stanfordmedicine.bsky.social are not obliged to take back Marty Makary, Vinay Prasad & Jay Bhattacharya when they leave the administration.
December 20, 2025 at 8:02 PM
Reposted by Michelle McCully
jilldlawrence.bsky.social
One of the best DOGE report cards I’ve seen is from @petridishes.bsky.social
www.theatlantic.com/newsletters/...
So, DOGE, What Would You Say You Did Here?
An exit interview
www.theatlantic.com
November 26, 2025 at 1:46 AM
Reposted by Michelle McCully
erosalie.infoepi.com
Imagine, if you will, that NASA updated its website to suggest gravity might not exist, prompting CalTech and CERN to release statements saying, "With great sadness, we can no longer recommend listening to NASA."

This is what's happening in epidemiology.
November 21, 2025 at 8:58 PM
Reposted by Michelle McCully
brittanytrang.com
A Sharon Begley byline, almost 5 years after her death.

Upon hearing the news James Watson had died, a STAT reporter said in our Slack, "I wish I could read what Sharon would have written."

Incredible news: Sharon in fact did pre-write a Watson obit. And it is masterful and excoriating.
🧪🧬🧫
James Watson, dead at 97, was a scientific legend and a pariah among his peers
James Watson, the co-discoverer of the structure of DNA who died Thursday at 97, was a scientific legend and a pariah among his peers.
www.statnews.com
November 8, 2025 at 1:39 PM
mccullylab.bsky.social
Seems like a good day to share one of my favorite videos on the internet 🧬
Rosalind Franklin vs. Watson & Crick - Science History Rap Battle
YouTube video by Science With Tom
youtu.be
November 8, 2025 at 8:53 PM
Reposted by Michelle McCully
pedsaly.bsky.social
In honor of Halloween, one of my all-time favorite cartoons by @katiemckissick.bsky.social

#MedSky #IDSky #HappyHalloween 💊👻🎃
Cartoon of person dressed as a ghost, speaking to another person What are you supposed to be? “An unfinished course of antibiotics. I can lead to antibiotic resistance Aren't I terrifying?” And Beatrice was never invited to a Halloween party ever again. By Beatrice the Biologist
October 31, 2025 at 10:26 PM
Reposted by Michelle McCully
petridishes.bsky.social
STOP ASKING MIKE JOHNSON ABOUT THE NEWS! HE IS PROTECTING HIS MENTAL SPACE!
Mike Johnson: I Am Tuning Out the News Cycle to Focus on Self-Care
Don’t ask me about the news. I am protecting my mental space.
www.theatlantic.com
November 4, 2025 at 7:00 PM
Reposted by Michelle McCully
paulalanlevy.bsky.social
Public Citizen has an annual pumpkin carving competition. The Litigation Group won this year with this portrayal of the White House with the East Wing having been demolished.

Entries from other groups to come
October 29, 2025 at 10:05 PM
Reposted by Michelle McCully
kreadlab.bsky.social
chef's kiss 😘
October 28, 2025 at 4:36 PM
Reposted by Michelle McCully
carolynbertozzi.bskyverified.social
Pres. Kornbluth articulates such moral clarity in this rejection of the proposed “compact”:

“the premise of the document is inconsistent with our core belief that scientific funding should be based on scientific merit alone”

orgchart.mit.edu/letters/rega...
Regarding the Compact | MIT Organization Chart
orgchart.mit.edu
October 10, 2025 at 6:53 PM
Reposted by Michelle McCully
markusdeserno.bsky.social
I am super excited to announce that we have a tenure-track faculty position in biophysics open in the Department of Physics at Carnegie Mellon! 🧪

Interfolio link: apply.interfolio.com/174360

PLEASE, share widely across the blue skies!

Let me briefly explain what we're looking for:

1/10
Tenure-track Position in Biophysics at Carnegie Mellon University, Department of Physics Location: Pittsburgh, PA Open Date: Sep 19, 2025 Description The Department of Physics at Carnegie Mellon University invites applications for a tenure-track faculty position in biophysics. The appointment is intended to be at the Assistant Professor level, but exceptional candidates at a higher level may also be considered. We seek outstanding candidates with a strong record in cellular and subcellular biophysics. Topics of particular interest include, but are not limited to, uncovering how key characteristics of living systems arise from the interplay between supramolecular cellular structures, how the emergent cellular circuitry defines goals and enables robust decision making, and how metabolic resources are allocated. This encompasses understanding of how information is learned, stored, transduced, and processed across subcellular structures. Applicants with theoretical, data science, or experimental backgrounds within biological physics are encouraged to apply. The ideal candidate will strengthen and extend research programs of current biophysics faculty in the Department of Physics and collaborate with broader life science activities across many departments at CMU and the wider Pittsburgh area. More details on Interfolio: https://apply.interfolio.com/174360
September 26, 2025 at 3:35 PM
Reposted by Michelle McCully
melbuer.bsky.social
Loyola Marymount University claims religious exemption with the NLRB, claws back recognition of NTT faculty union

The sudden decision of the LMU Board of Trustees has left many NTT faculty in shock; the union plans a response.
Loyola Marymount University claims religious exemption with the NLRB, claws back recognition of NTT faculty union
The sudden decision of the LMU Board of Trustees has left many NTT faculty in shock; the union plans a response.
wordsaboutwork.blog
September 16, 2025 at 10:41 PM
Reposted by Michelle McCully
standupforscience.bsky.social
DUCK AROUND, FIND OUT! With our duck delivery in tow, we waddled up to the Hill to let our representatives know that it's time to send the Quack-In-Chief packing. #ImpeachRFK
September 16, 2025 at 9:37 PM
Reposted by Michelle McCully
tagerai.bsky.social
Update on this story: As many of us feared, it turns out that Berkeley wasn't the only UC to release personal info on its pro-palestine anti-genocide professors to the justice department, it looks they they all did. Berkeley was just the only one to tell profs they did it.
September 16, 2025 at 9:41 PM
Reposted by Michelle McCully
cbartman.bsky.social
NSF GRFP announcement was posted! Have not read the details to see if any changes from previous years...

www.nsf.gov/funding/oppo...
NSF Graduate Research Fellowship Program (GRFP)
www.nsf.gov
September 9, 2025 at 12:05 PM