Surace Lab
@suracelab.bsky.social
Metabolism lovers! We are busy understanding how diet and lifestyle influence tissue-resident lymphocytes biology in homeostasis and disease!! 👩🏻🔬🧑🔬 🥼 🧪🧫
Nice meeting everybody again and having great discussions! I have learned a lot of new things :)
Good job Ivan from our lab @suracelab.bsky.social for getting the poster prize !🏆 and Tim from @labwilhelm.bsky.social for getting the talk prize!🏆 congrats both of you!
#clustersciencedays2025 days
Good job Ivan from our lab @suracelab.bsky.social for getting the poster prize !🏆 and Tim from @labwilhelm.bsky.social for getting the talk prize!🏆 congrats both of you!
#clustersciencedays2025 days
The Cluster Science Days 2025 were a very joyful event bringing together our Bonn scientists to share ideas and to network.
During the event the Cluster participants could enjoy talks, interactive poster sessions and a fun evening program in a comfortable atmosphere fostering scientific exchange.
During the event the Cluster participants could enjoy talks, interactive poster sessions and a fun evening program in a comfortable atmosphere fostering scientific exchange.
November 23, 2025 at 4:14 PM
Nice meeting everybody again and having great discussions! I have learned a lot of new things :)
Good job Ivan from our lab @suracelab.bsky.social for getting the poster prize !🏆 and Tim from @labwilhelm.bsky.social for getting the talk prize!🏆 congrats both of you!
#clustersciencedays2025 days
Good job Ivan from our lab @suracelab.bsky.social for getting the poster prize !🏆 and Tim from @labwilhelm.bsky.social for getting the talk prize!🏆 congrats both of you!
#clustersciencedays2025 days
Reposted by Surace Lab
🚨 #Job alert! The group of Johannes Brägelmann at the Medical ClinicIII at the University Hospital in Bonn is offering 2 PhD positions:
1) PhD in Cancer Immunology
Link: www.immunosensation.de/opportunitie...
2) PhD in Spatial Cancer Biology
Link: www.immunosensation.de/opportunitie...
Apply now!
1) PhD in Cancer Immunology
Link: www.immunosensation.de/opportunitie...
2) PhD in Spatial Cancer Biology
Link: www.immunosensation.de/opportunitie...
Apply now!
August 11, 2025 at 8:55 AM
🚨 #Job alert! The group of Johannes Brägelmann at the Medical ClinicIII at the University Hospital in Bonn is offering 2 PhD positions:
1) PhD in Cancer Immunology
Link: www.immunosensation.de/opportunitie...
2) PhD in Spatial Cancer Biology
Link: www.immunosensation.de/opportunitie...
Apply now!
1) PhD in Cancer Immunology
Link: www.immunosensation.de/opportunitie...
2) PhD in Spatial Cancer Biology
Link: www.immunosensation.de/opportunitie...
Apply now!
Reposted by Surace Lab
Cysteinyl leukotrienes are important drivers of the anaphylactic response to ingested food antigens @science.org
Comment: www.science.org/doi/10.1126/...
on @rmedzhitov.bsky.social @stephanieeisen.bsky.social
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Comment: www.science.org/doi/10.1126/...
on @rmedzhitov.bsky.social @stephanieeisen.bsky.social
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Opening the gateway to food-induced anaphylaxis
Cysteinyl leukotrienes are important drivers of the anaphylactic response to ingested food antigens
www.science.org
August 7, 2025 at 7:35 PM
Cysteinyl leukotrienes are important drivers of the anaphylactic response to ingested food antigens @science.org
Comment: www.science.org/doi/10.1126/...
on @rmedzhitov.bsky.social @stephanieeisen.bsky.social
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Comment: www.science.org/doi/10.1126/...
on @rmedzhitov.bsky.social @stephanieeisen.bsky.social
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Reposted by Surace Lab
Microbial riboflavin inhibits ceramide synthase 3 to lower ceramide (d18:1/26:0) and delay colorectal cancer progression: Cell Metabolism www.cell.com/cell-metabol...
Microbial riboflavin inhibits ceramide synthase 3 to lower ceramide (d18:1/26:0) and delay colorectal cancer progression
This study identifies C26 ceramide and CERS3 as critical factors in colorectal cancer
progression, which is modulated by microbial metabolite riboflavin. C26 ceramide directly
activates EGFR, and the ...
www.cell.com
July 3, 2025 at 6:39 PM
Microbial riboflavin inhibits ceramide synthase 3 to lower ceramide (d18:1/26:0) and delay colorectal cancer progression: Cell Metabolism www.cell.com/cell-metabol...
Reposted by Surace Lab
Woohoo! From superstars ionut and Marta in the Frisén lab! www.science.org/doi/10.1126/... can’t wait to see what the anti-neurogenesis folks say about it 😃
Identification of proliferating neural progenitors in the adult human hippocampus
Continuous adult hippocampal neurogenesis is involved in memory formation and mood regulation but is challenging to study in humans. Difficulties finding proliferating progenitor cells called into que...
www.science.org
July 3, 2025 at 6:54 PM
Woohoo! From superstars ionut and Marta in the Frisén lab! www.science.org/doi/10.1126/... can’t wait to see what the anti-neurogenesis folks say about it 😃
Reposted by Surace Lab
We are all somatic mutation mosaics.
"There are trillions of cells in a human body and so the total number of somatic mutations acquired in a single individual may well exceed quadrillions, millions of times the size of the human genome."
@nature.com
nature.com/articles/s41...
"There are trillions of cells in a human body and so the total number of somatic mutations acquired in a single individual may well exceed quadrillions, millions of times the size of the human genome."
@nature.com
nature.com/articles/s41...
The Somatic Mosaicism across Human Tissues Network - Nature
The Somatic Mosaicism across Human Tissues Network aims to create a reference catalogue of somatic mosaicism across different tissues and cells within individuals.
nature.com
July 2, 2025 at 4:21 PM
We are all somatic mutation mosaics.
"There are trillions of cells in a human body and so the total number of somatic mutations acquired in a single individual may well exceed quadrillions, millions of times the size of the human genome."
@nature.com
nature.com/articles/s41...
"There are trillions of cells in a human body and so the total number of somatic mutations acquired in a single individual may well exceed quadrillions, millions of times the size of the human genome."
@nature.com
nature.com/articles/s41...
Reposted by Surace Lab
Excited to share our new work in PDAC Cachexia. This work demonstrated that addition of factors like advanced age in murine models can uncover signatures that might have been obscured in other models.
Grateful for @jdoles.bsky.social ‘s mentorship and support!
Looking forward to all feedback :)
Grateful for @jdoles.bsky.social ‘s mentorship and support!
Looking forward to all feedback :)
Cachexia is a devastating cancer comorbidity that impacts numerous cancer outcomes. In @jem.org, @aneedasgupta.bsky.social, @jdoles.bsky.social et al describe a novel metabolic pathway/target w/ clinical implications for the treatment of cachectic #PancreaticCancer rupress.org/jem/article/...
July 2, 2025 at 4:49 PM
Excited to share our new work in PDAC Cachexia. This work demonstrated that addition of factors like advanced age in murine models can uncover signatures that might have been obscured in other models.
Grateful for @jdoles.bsky.social ‘s mentorship and support!
Looking forward to all feedback :)
Grateful for @jdoles.bsky.social ‘s mentorship and support!
Looking forward to all feedback :)
Reposted by Surace Lab
I feel very lucky that science is my job… I feel even better when I think about the amazing people that I get to see everyday !
Ladies and gentleman…..The fairies 🧚🏻 from @labwilhelm.bsky.social and the fluorochromes (+ bad comp) from our @suracelab.bsky.social !
Ladies and gentleman…..The fairies 🧚🏻 from @labwilhelm.bsky.social and the fluorochromes (+ bad comp) from our @suracelab.bsky.social !
February 27, 2025 at 6:41 PM
I feel very lucky that science is my job… I feel even better when I think about the amazing people that I get to see everyday !
Ladies and gentleman…..The fairies 🧚🏻 from @labwilhelm.bsky.social and the fluorochromes (+ bad comp) from our @suracelab.bsky.social !
Ladies and gentleman…..The fairies 🧚🏻 from @labwilhelm.bsky.social and the fluorochromes (+ bad comp) from our @suracelab.bsky.social !
Reposted by Surace Lab
🚨 Job alert 🚨
1 PhD + 1 Technician
Our lab is looking for motivated candidates interested in understanding the impact of diets and lifestyle on tumor development, anti-tumor immunity and metastasis! Apply and join our team!
Info below 👇
1 PhD + 1 Technician
Our lab is looking for motivated candidates interested in understanding the impact of diets and lifestyle on tumor development, anti-tumor immunity and metastasis! Apply and join our team!
Info below 👇
January 14, 2025 at 7:28 PM
🚨 Job alert 🚨
1 PhD + 1 Technician
Our lab is looking for motivated candidates interested in understanding the impact of diets and lifestyle on tumor development, anti-tumor immunity and metastasis! Apply and join our team!
Info below 👇
1 PhD + 1 Technician
Our lab is looking for motivated candidates interested in understanding the impact of diets and lifestyle on tumor development, anti-tumor immunity and metastasis! Apply and join our team!
Info below 👇
Reposted by Surace Lab
🚨 Open #position! The group of Christoph Wilhelm at the University Hospital Bonn is looking for a
Postdoctoral fellow (m/f/d) – metabolic and nutritional regulation of immunity
Application deadline is February 10!
Visit our website for more information.
#job #postdoc #science #immunology
Postdoctoral fellow (m/f/d) – metabolic and nutritional regulation of immunity
Application deadline is February 10!
Visit our website for more information.
#job #postdoc #science #immunology
January 15, 2025 at 6:54 AM
🚨 Open #position! The group of Christoph Wilhelm at the University Hospital Bonn is looking for a
Postdoctoral fellow (m/f/d) – metabolic and nutritional regulation of immunity
Application deadline is February 10!
Visit our website for more information.
#job #postdoc #science #immunology
Postdoctoral fellow (m/f/d) – metabolic and nutritional regulation of immunity
Application deadline is February 10!
Visit our website for more information.
#job #postdoc #science #immunology
Reposted by Surace Lab
#Immunology out now @science.org
ILC2s contribute to glucose homeostasis. Neurons that innervate the gut from areas of the brain associated with glucose sensing can stimulate ILC2s in the gut to relocate to the pancreas upon fasting.
https://buff.ly/42iBst0
ILC2s contribute to glucose homeostasis. Neurons that innervate the gut from areas of the brain associated with glucose sensing can stimulate ILC2s in the gut to relocate to the pancreas upon fasting.
https://buff.ly/42iBst0
January 16, 2025 at 7:20 PM
#Immunology out now @science.org
ILC2s contribute to glucose homeostasis. Neurons that innervate the gut from areas of the brain associated with glucose sensing can stimulate ILC2s in the gut to relocate to the pancreas upon fasting.
https://buff.ly/42iBst0
ILC2s contribute to glucose homeostasis. Neurons that innervate the gut from areas of the brain associated with glucose sensing can stimulate ILC2s in the gut to relocate to the pancreas upon fasting.
https://buff.ly/42iBst0
🚨 Job alert 🚨
1 PhD + 1 Technician
Our lab is looking for motivated candidates interested in understanding the impact of diets and lifestyle on tumor development, anti-tumor immunity and metastasis! Apply and join our team!
Info below 👇
1 PhD + 1 Technician
Our lab is looking for motivated candidates interested in understanding the impact of diets and lifestyle on tumor development, anti-tumor immunity and metastasis! Apply and join our team!
Info below 👇
January 14, 2025 at 7:28 PM
🚨 Job alert 🚨
1 PhD + 1 Technician
Our lab is looking for motivated candidates interested in understanding the impact of diets and lifestyle on tumor development, anti-tumor immunity and metastasis! Apply and join our team!
Info below 👇
1 PhD + 1 Technician
Our lab is looking for motivated candidates interested in understanding the impact of diets and lifestyle on tumor development, anti-tumor immunity and metastasis! Apply and join our team!
Info below 👇
Reposted by Surace Lab
Effects of Aging on Glucose and Lipid Metabolism in Mice
congrats @mvhlab.bsky.social !
onlinelibrary.wiley.com/doi/10.1111/...
congrats @mvhlab.bsky.social !
onlinelibrary.wiley.com/doi/10.1111/...
Effects of Aging on Glucose and Lipid Metabolism in Mice
Lien et al. report a characterization of metabolism with aging across three different strains of mice. They find that glucose metabolism is robust during healthy aging; however, aging tissues exhibit....
onlinelibrary.wiley.com
December 29, 2024 at 7:01 AM
Effects of Aging on Glucose and Lipid Metabolism in Mice
congrats @mvhlab.bsky.social !
onlinelibrary.wiley.com/doi/10.1111/...
congrats @mvhlab.bsky.social !
onlinelibrary.wiley.com/doi/10.1111/...
Reposted by Surace Lab
For those starting on BSKY and loving #metabolism and #mitochondria, the 2 starter packs have now been completed. 300 scientists working in this field are here to be followed! Happy Boxing Day
Starter pack 1: go.bsky.app/VavECSX
Starter pack 2: go.bsky.app/CH1MctZ
Starter pack 1: go.bsky.app/VavECSX
Starter pack 2: go.bsky.app/CH1MctZ
a stack of gift boxes with the words happy boxing day below
ALT: a stack of gift boxes with the words happy boxing day below
media.tenor.com
December 26, 2024 at 8:20 AM
For those starting on BSKY and loving #metabolism and #mitochondria, the 2 starter packs have now been completed. 300 scientists working in this field are here to be followed! Happy Boxing Day
Starter pack 1: go.bsky.app/VavECSX
Starter pack 2: go.bsky.app/CH1MctZ
Starter pack 1: go.bsky.app/VavECSX
Starter pack 2: go.bsky.app/CH1MctZ
What a great year for our group! Thanks guys for your constant support, the passion and the hard work you put to bring forward our ideas and projects, and also …. for being amazing Artists&chef pâtissier!
With a photo of the latest ArtAttack, we wish everybody merry Christmas and happy new year!
With a photo of the latest ArtAttack, we wish everybody merry Christmas and happy new year!
December 20, 2024 at 10:10 PM
What a great year for our group! Thanks guys for your constant support, the passion and the hard work you put to bring forward our ideas and projects, and also …. for being amazing Artists&chef pâtissier!
With a photo of the latest ArtAttack, we wish everybody merry Christmas and happy new year!
With a photo of the latest ArtAttack, we wish everybody merry Christmas and happy new year!
Reposted by Surace Lab
#Immunology by First release now @science.org
Identification of APCs in the gut that promote Treg differentiation and how tolerance to food antigens is influenced by helminth infection
https://buff.ly/3DjNQ1e
By Maria Canesso, @danmucida.bsky.social , @victora.bsky.social and colleagues.
Identification of APCs in the gut that promote Treg differentiation and how tolerance to food antigens is influenced by helminth infection
https://buff.ly/3DjNQ1e
By Maria Canesso, @danmucida.bsky.social , @victora.bsky.social and colleagues.
December 19, 2024 at 8:08 PM
#Immunology by First release now @science.org
Identification of APCs in the gut that promote Treg differentiation and how tolerance to food antigens is influenced by helminth infection
https://buff.ly/3DjNQ1e
By Maria Canesso, @danmucida.bsky.social , @victora.bsky.social and colleagues.
Identification of APCs in the gut that promote Treg differentiation and how tolerance to food antigens is influenced by helminth infection
https://buff.ly/3DjNQ1e
By Maria Canesso, @danmucida.bsky.social , @victora.bsky.social and colleagues.
Reposted by Surace Lab
A very rare position for an immunology professorship at Cambridge. Something to think about!
www.jobs.cam.ac.uk/job/49381/
www.jobs.cam.ac.uk/job/49381/
Associate Professor/Professor of Infection and/or Immunity - Job Opportunities - University of Cambridge
Associate Professor/Professor of Infection and/or Immunity in the Department of Pathology at the University of Cambridge.
www.jobs.cam.ac.uk
December 13, 2024 at 9:53 AM
A very rare position for an immunology professorship at Cambridge. Something to think about!
www.jobs.cam.ac.uk/job/49381/
www.jobs.cam.ac.uk/job/49381/
inherited genetic alteration governs breast cancer metastasis .. interesting work on the hereditary basis of metastasis !
www.cell.com/cell/abstrac...
www.cell.com/cell/abstrac...
A commonly inherited human PCSK9 germline variant drives breast cancer metastasis via LRP1 receptor
Characterization of a common germline variant in PCSK9 unveils a hereditary basis underlying breast cancer metastasis and suggests that PCSK9 inhibition therapy could be a promising strategy for breast cancer metastasis prevention.
www.cell.com
December 12, 2024 at 11:38 PM
inherited genetic alteration governs breast cancer metastasis .. interesting work on the hereditary basis of metastasis !
www.cell.com/cell/abstrac...
www.cell.com/cell/abstrac...
Reposted by Surace Lab
Gearing up vs the potential of building "mirror life"
A looming danger of bioengineered reversed-chirality bacteria and microbes.
www.science.org/doi/10.1126/... @science.org
A looming danger of bioengineered reversed-chirality bacteria and microbes.
www.science.org/doi/10.1126/... @science.org
Confronting risks of mirror life
Broad discussion is needed to chart a path forward.
www.science.org
December 12, 2024 at 7:41 PM
Gearing up vs the potential of building "mirror life"
A looming danger of bioengineered reversed-chirality bacteria and microbes.
www.science.org/doi/10.1126/... @science.org
A looming danger of bioengineered reversed-chirality bacteria and microbes.
www.science.org/doi/10.1126/... @science.org
Reposted by Surace Lab
Lipid-delivery of mRNA to placenta to treat pre-eclampsia
www.nature.com/articles/d41...
www.nature.com/articles/s41...
www.nature.com/articles/d41...
www.nature.com/articles/s41...
Lipid-delivery system could treat life-threatening pregnancy complication
Testing lipid nanoparticles for pre-eclampsia treatment.
www.nature.com
December 12, 2024 at 2:51 AM
Lipid-delivery of mRNA to placenta to treat pre-eclampsia
www.nature.com/articles/d41...
www.nature.com/articles/s41...
www.nature.com/articles/d41...
www.nature.com/articles/s41...
Reposted by Surace Lab
Wow just wow. I did not have on my bingo card an mRNA therapeutic for treating pre eclampsia. A VEGF tropic mRNA resolved maternal hypertension until pregnancy in a mouse model of the condition. Really fascinating science.
🧪
www.nature.com/articles/s41...
🧪
www.nature.com/articles/s41...
Placenta-tropic VEGF mRNA lipid nanoparticles ameliorate murine pre-eclampsia - Nature
A platform for mRNA lipid nanoparticle delivery to the placenta to treat pre-eclampsia is shown to improve fetal and maternal health in mice and has potential clinical applications in obstetric d...
www.nature.com
December 12, 2024 at 12:52 PM
Wow just wow. I did not have on my bingo card an mRNA therapeutic for treating pre eclampsia. A VEGF tropic mRNA resolved maternal hypertension until pregnancy in a mouse model of the condition. Really fascinating science.
🧪
www.nature.com/articles/s41...
🧪
www.nature.com/articles/s41...
Reposted by Surace Lab
Friends, it's fun to see the #immunology community continue to grow! I created a 4th Starter Pack to help folks find each other. If you're an immunologist and you don't see yourself on the lists, let me know 🧪
go.bsky.app/PY5tCas
go.bsky.app/FmERUoD
go.bsky.app/6aT6qDS
go.bsky.app/QSEPDoj
go.bsky.app/PY5tCas
go.bsky.app/FmERUoD
go.bsky.app/6aT6qDS
go.bsky.app/QSEPDoj
Friends, the second #immunology starter pack filled in 3 days! I started a third to help folks new to BlueSky rebuild their network
Below are the links
If you're an immunologist and I have missed you so far, let me know 🧪
go.bsky.app/PY5tCas
go.bsky.app/FmERUoD
go.bsky.app/6aT6qDS
Below are the links
If you're an immunologist and I have missed you so far, let me know 🧪
go.bsky.app/PY5tCas
go.bsky.app/FmERUoD
go.bsky.app/6aT6qDS
Wonderful to see the #immunology community growing here.
The first starter pack is full (they cap at 150), so I created a second one. Let me know if you'd like to be added
go.bsky.app/PY5tCas
go.bsky.app/FmERUoD
The first starter pack is full (they cap at 150), so I created a second one. Let me know if you'd like to be added
go.bsky.app/PY5tCas
go.bsky.app/FmERUoD
November 29, 2024 at 4:47 PM
Friends, it's fun to see the #immunology community continue to grow! I created a 4th Starter Pack to help folks find each other. If you're an immunologist and you don't see yourself on the lists, let me know 🧪
go.bsky.app/PY5tCas
go.bsky.app/FmERUoD
go.bsky.app/6aT6qDS
go.bsky.app/QSEPDoj
go.bsky.app/PY5tCas
go.bsky.app/FmERUoD
go.bsky.app/6aT6qDS
go.bsky.app/QSEPDoj
Reposted by Surace Lab
Fascinating new paper about how commensal #fungi can promote #type2 responses in mice, a process involving fungal induction of #IL-33 🍄 🧪 #ImmunoSky www.nature.com/articles/s41...
Fungal symbiont transmitted by free-living mice promotes type 2 immunity - Nature
Kazachstania pintolopesii is a highly prevalent fungal symbiont that can trigger type 2 immunity and influence the composition of the gut mycobiome, as well as immune and disease phenotypes.
www.nature.com
November 29, 2024 at 12:05 PM
Fascinating new paper about how commensal #fungi can promote #type2 responses in mice, a process involving fungal induction of #IL-33 🍄 🧪 #ImmunoSky www.nature.com/articles/s41...
Reposted by Surace Lab
We are recruiting an associate or full Professor of Infection and/or Immunity to the school biological sciences in Cambridge. Full details here: www.jobs.cam.ac.uk/job/49381/
#immunology #virology
#immunology #virology
Associate Professor/Professor of Infection and/or Immunity - Job Opportunities - University of Cambridge
Associate Professor/Professor of Infection and/or Immunity in the Department of Pathology at the University of Cambridge.
www.jobs.cam.ac.uk
November 29, 2024 at 7:10 PM
We are recruiting an associate or full Professor of Infection and/or Immunity to the school biological sciences in Cambridge. Full details here: www.jobs.cam.ac.uk/job/49381/
#immunology #virology
#immunology #virology