Robert Jansen
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robertsjansen.bsky.social
Robert Jansen
@robertsjansen.bsky.social
250 followers 200 following 11 posts
Assistant Professor in microbial metabolism at Radboud University. I explore new functions of enzymes and metabolites using untargeted metabolomics and like to 🏃

www.functional-metabolomics-lab.nl
Posts Replies Media Videos
Reposted by Robert Jansen
cp-cellchembiol.bsky.social
Online now! Online now! The limitations of small molecule and genetic screening in phenotypic drug discovery #chembiol
The limitations of small molecule and genetic screening in phenotypic drug discovery
Phenotypic drug discovery is a powerful tool for uncovering new therapies, but small molecule and genetic screens each have distinct limitations. Vincent and Gianni analyze these challenges and suggest practical mitigation strategies to maximize screening success.
dlvr.it
November 18, 2025 at 4:30 PM
Reposted by Robert Jansen
sfmpathogenesis.bsky.social
Two M. tuberculosis RelE toxins don’t cut mRNA, they slice 16S rRNA itself, shutting down translation in a totally unexpected way, new study reveals.
A big leap in understanding TB’s survival tricks and new angles for therapies.

📖 shorturl.at/Z8MVX
✍️ @genevauxpierre.bsky.social & coll.
#MicroSky
November 18, 2025 at 8:56 AM
Reposted by Robert Jansen
thebrysonlab.bsky.social
Excited to share our lab's newest preprint (strap in if you're excited about metabolism, species differences, or Mtb gene expression): www.biorxiv.org/content/10.1...
Systems analysis reveals alternate metabolic states adopted by Mycobacterium tuberculosis across species
Mycobacterium tuberculosis (Mtb) persists within macrophages, yet how different host species shape bacterial state remains poorly understood. Here, we directly compared the intracellular transcriptome...
www.biorxiv.org
November 17, 2025 at 6:20 AM
Reposted by Robert Jansen
luizcarvalholab.bsky.social
With the Wilmanns lab @embl.org we reveal cryoEM structures of an essential, bifunctional acyl-CoA carboxylase from mycobacteria. @wertheimufscripps.bsky.social

This ~ 600 kDa enzyme is asymmetric, rotatory, has unusual stoichiometry, and unique E5 subunits.

www.biorxiv.org/content/10.1...
www.biorxiv.org
November 17, 2025 at 1:38 PM
Reposted by Robert Jansen
who.int
#Tuberculosis (TB) is preventable and curable.

Yet, it remains one of the world’s deadliest infectious killers, claiming 1.23 million lives in 2024.

The WHO Global Tuberculosis Report 2025 talks about the gains made so far and the challenges ahead due to severe funding cuts: bit.ly/4qT5ihk
Image of a patient in the x-ray laboratory in the background. Text reads 'Tuberculosis is the world's top infectious killer. TB caused 1.23 million deaths in 2024. Ending TB is possible. Fund it, research it, commit to it.'
November 12, 2025 at 2:51 PM
Reposted by Robert Jansen
nizet.bsky.social
November 12, 2025 at 1:15 PM
Reposted by Robert Jansen
kshbeckham.bsky.social
Want to find ways to combat TB? Check out this PhD position 👇
November 2, 2025 at 8:44 PM
Reposted by Robert Jansen
jjjvanderhooft.bsky.social
🚨 New Resource & Preprint Alert 🚨

This resource collected by the mFam consortiun led by Gerd Balcke and Steffen Neumann contributes >7000 mass spectra of 2,126 unique metabolites to the public domain through MassBank.
Preprint: lnkd.in/eYcJMqYn
Interactive plot: lnkd.in/egBaTTNH

#CompMetabolomics
November 1, 2025 at 7:14 PM
Reposted by Robert Jansen
danybeste.bsky.social
www.biorxiv.org/content/10.1...
Read it if you dare. Happy Halloween
VadK, a Non-Canonical Kinase that Regulates the Methylcitrate Cycle and is Essential for Mycobacterium tuberculosis Virulence
The evolution of new enzymatic functions is constrained and guided by the architecture of an organisms metabolic and regulatory networks as well as by environmental constraints. Here, we identify a pr...
www.biorxiv.org
October 31, 2025 at 5:05 PM
Reposted by Robert Jansen
carolynbertozzi.bskyverified.social
For those who perform thermal proteome profiling (TPP) experiments, you might find this new data analysis approach (and open source Python software) useful. Developed by postdoc @jfhevler.bsky.social 🙏

arxiv.org/abs/2508.096...
Thermal Tracks: A Gaussian process-based framework for universal melting curve analysis enabling unconstrained hit identification in thermal proteome profiling experiments
Thermal Tracks is a Python-based statistical framework for analyzing protein thermal stability data that overcomes key limitations of existing thermal proteome profiling (TPP) work-flows. Unlike stand...
arxiv.org
October 24, 2025 at 10:18 PM
Reposted by Robert Jansen
kostchristian.bsky.social
#microsky #mevosky @spp2389.bsky.social

A PhD position is available in my lab to work on:

Emergence and self-organisation of bacterial metabolism in consortia of cross-feeding bacteria.

Please RT

Deadline: 12.11.25

More infos 👇
shorturl.at/rAKAT
October 28, 2025 at 8:43 AM
Reposted by Robert Jansen
geiselbiofilm.bsky.social
Pls share:
A postdoctoral research position is available in the group of Prof. Dr. Kirsten Jung at Ludwig-Maximilians-Universität München, Germany focusing on SRBs (www.bio.lmu.de/en/research/...)
Molecular Microbiology Group
Information about research topics and publications about the group around Kirsten Jung
www.bio.lmu.de
October 21, 2025 at 7:49 PM
Reposted by Robert Jansen
emmseveri.bsky.social
www.nature.com/articles/s41...

#microsky #microbiome
Predicting functions of uncharacterized gene products from microbial communities - Nature Biotechnology
FUGAsseM predicts protein function in microbiomes using coexpression patterns from metatranscriptomes and diverse community-wide data.
www.nature.com
October 16, 2025 at 4:50 AM
Reposted by Robert Jansen
mattolm.bsky.social
My fantastic department at CU Boulder is hiring a tenure-track Assistant Professor! This is a broad search spanning nearly all areas of biology. Applications are due Nov 13, 2025. Feel free to reach out to me with questions, and please share widely.
jobs.colorado.edu/jobs/JobDeta...
October 17, 2025 at 4:00 PM
Reposted by Robert Jansen
helmholtzhzi.bsky.social
We are looking for a new generation of scientists pushing the boundaries of infection research and using AI to shape the future of health research.
🚀Apply for junior group leader positions in our HUMAN program by November 26.
www.helmholtz-hzi.de/en/career/jo...
www.helmholtz-hzi.de/en/career/jo...
Ankündigung von offenen Stellen am Helmholtz-Zentrum für Infektionsforschung mit QR-Codes zu den Stellenanzeigen
October 16, 2025 at 1:01 PM
Reposted by Robert Jansen
kostchristian.bsky.social
#microsky #mevosky @spp2389.bsky.social

A PhD position is available in my lab to work on:

Emergence and self-organisation of bacterial metabolism in consortia of cross-feeding bacteria.

Please RT

Deadline: 12.11.25

More infos 👇
shorturl.at/rAKAT
October 15, 2025 at 1:07 PM
Reposted by Robert Jansen
stanvanpelt.bsky.social
What a journey this book copy made! It was great meeting @elisabethbik.bsky.social in persoon again, and to hear her talk about science integrity issues at @isis-radboud.bsky.social this afternoon.
October 14, 2025 at 5:33 PM
Reposted by Robert Jansen
elisabethbik.bsky.social
I will be bringing my copy of @stanvanpelt.bsky.social's new book Sloppy Science (in Dutch) to read in the train.

I hope he can sign it for me!

www.lebowskipublishers.nl/boek/3331/st...
Photo of my right hand holding a book. It has a white cover with black letters: Stan van Pelt Sloppy Science Alles over wetenschapsfraude: van foutjes to nepcongressen And it features a blue abstract smear on the front
October 13, 2025 at 8:17 AM
Reposted by Robert Jansen
peiferlabunc.bsky.social
I'm very excited to announce that UNC Biology has 6 faculty positions open this year! The first is for an Asst Professor who studies organismal resilience using an integrative approach 1/n
unc.peopleadmin.com/postings/307...
Poster with QR code linking to the position
October 12, 2025 at 2:20 PM
Reposted by Robert Jansen
jamesbriscoe.bsky.social
The @crick.ac.uk is recruiting Early Career Group Leaders

- Lab set-up, research costs, salaries for up to 5 researchers
- Support for up to 12 years
- Access to our core facilities
- Competitive salary
- Fantastic colleagues
- All areas of biology

Deadline 27 Nov

www.crick.ac.uk/careers-stud...
Early career group leaders
We appoint researchers from across biology and biomedicine to set up their first groups at the Crick.
www.crick.ac.uk
October 10, 2025 at 8:20 AM
Reposted by Robert Jansen
vscooper.micropopbio.org
Reposting, submit soon!
vscooper.micropopbio.org Vaughn Cooper @vscooper.micropopbio.org · Sep 23
🚨 Microbiologists! We are recruiting Assistant / Associate Professors in 3 collaborative areas of our U. Pittsburgh School of Medicine.
1) MMG (my dept): fundamental research in med micro
2) Peds ID / I4Kids institute
3) Center for Vaccine Research
🔗 to all 3 w/info: www.linkedin.com/posts/vaughn...
Faculty Professor Associate - Full-Time | Vaughn Cooper
We are recruiting Faculty microbiologists in three (3) different, complementary, and collaborative areas at the University of Pittsburgh associated with the School of Medicine. 1) Fundamental researc...
www.linkedin.com
October 8, 2025 at 12:16 AM
Reposted by Robert Jansen
jebyrnes.bsky.social
Heeeeey #Microbial #Ecology folk! My department has a job opening for a tenure track Microbial Ecologist! Feel free to DM me with questions. Come join our awesome supportive whip-smart & kind crew in the Biology Department of @umassboston.bsky.social! employmentopportunities.umb.edu/boston/en-us...
The ISC - your new home at UMass Boston? The view of Boston Harbor from front of campus
October 7, 2025 at 2:01 PM
Reposted by Robert Jansen
heran.bsky.social
We're hiring! Check out our ad and please re-post or forward to interested #Microbiology parties: apply.interfolio.com/174783
Apply - Interfolio {{$ctrl.$state.data.pageTitle}} - Apply - Interfolio
apply.interfolio.com
October 7, 2025 at 4:10 PM
Reposted by Robert Jansen
ianlmorgan.bsky.social
This is a great op-ed by Dr. Stanley about the effects of anti-science politicized attacks on "gain-of-function" research. Much of this research poses little risk and has huge benefits for people across the globe. If your research has been affected, please consider writing an op-ed like Dr. Stanley.
The NIH ordered me to stop my ‘dangerous’ gain-of-function research. It isn’t dangerous at all
Safe gain-of-function research is necessary to identify new treatments for diseases like for tuberculosis — but the NIH has imposed unfounded stops.
www.statnews.com
October 6, 2025 at 2:18 PM
Reposted by Robert Jansen
erinrgreen.bsky.social
Job alert ‼️ UChicago Micro is hiring! Open to tenured/tenure track faculty at all levels in any area of microbiology. Come join our amazing and growing department. apply.interfolio.com/174404
October 4, 2025 at 6:44 PM