Michael Riedl
@mriedl.bsky.social
Postdoc Brugues Lab at MPI-CBG / TUD
PhD Sixt and Hof Group at ISTA
Engineer in Biophysics
-
Active matter, Cell Biology, Chaos to Order, Synchronization, Emergent Behavior -
Team Toy Science.
PhD Sixt and Hof Group at ISTA
Engineer in Biophysics
-
Active matter, Cell Biology, Chaos to Order, Synchronization, Emergent Behavior -
Team Toy Science.
Pinned
Michael Riedl
@mriedl.bsky.social
· Nov 14
Polymerizing actin creates fireworks that are a sight to behold. This excitable medium produces polymerizing waves similar to those observed in other context. The parallels I tried to lay out in this perspective piece last year: tinyurl.com/53cbxm4v
(LifeAct-GFP in Endothelial Cell)
(LifeAct-GFP in Endothelial Cell)
Reposted by Michael Riedl
To recognise and celebrate @svobodalab.bsky.social's pivotal contribution to Woodstock Bio2 + Night Science, #TCTeAC, I am starting this "What Petr Svoboda did at Woodstock?" thread. If you were there - #contribute and #retweet.
"Petr Didn’t Submit an Abstract. #TCTeAC Submitted to Him."
"Petr Didn’t Submit an Abstract. #TCTeAC Submitted to Him."
August 4, 2025 at 7:02 AM
To recognise and celebrate @svobodalab.bsky.social's pivotal contribution to Woodstock Bio2 + Night Science, #TCTeAC, I am starting this "What Petr Svoboda did at Woodstock?" thread. If you were there - #contribute and #retweet.
"Petr Didn’t Submit an Abstract. #TCTeAC Submitted to Him."
"Petr Didn’t Submit an Abstract. #TCTeAC Submitted to Him."
Reposted by Michael Riedl
Our study on endothelial mechanics made the news! 🤩
Super nice and clear article on our findings and their implications.
www.snexplores.org/article/how-...
Super nice and clear article on our findings and their implications.
www.snexplores.org/article/how-...
Here’s why your blood vessels don’t burst under pressure
Cells lining the blood vessels reorganize their inner structures to handle stressful boosts in pressure.
www.snexplores.org
July 17, 2025 at 9:27 AM
Our study on endothelial mechanics made the news! 🤩
Super nice and clear article on our findings and their implications.
www.snexplores.org/article/how-...
Super nice and clear article on our findings and their implications.
www.snexplores.org/article/how-...
Reposted by Michael Riedl
it appears your safe back-up post doc project wasn’t so risk free after all, mr. bond
June 21, 2025 at 6:18 PM
it appears your safe back-up post doc project wasn’t so risk free after all, mr. bond
Reposted by Michael Riedl
Amazing defense by @alisonkickuth.bsky.social! Congratulations on the beautiful thesis!
I successfully defended my PhD thesis this week! Thank you @brugueslab.bsky.social, @poldresden.bsky.social and @mpi-cbg.de for the great time over the last years!
June 13, 2025 at 3:25 PM
Amazing defense by @alisonkickuth.bsky.social! Congratulations on the beautiful thesis!
Reposted by Michael Riedl
Very happy and excited to share our latest work linking actin nematodynamics and endothelial cell mechanics under anisotropic tension, now published in @natphys.nature.com ! rdcu.be/eigWi
@ipparis.bsky.social @polytechniqueparis.bsky.social
@ipparis.bsky.social @polytechniqueparis.bsky.social
Interplay of actin nematodynamics and anisotropic tension controls endothelial mechanics
Nature Physics - Blood flow through a vessel deforms vessel walls. Cells lining these walls sense the changes in pressure as blood flows and reorient their actin fibres in the direction of largest...
rdcu.be
April 18, 2025 at 12:06 PM
Very happy and excited to share our latest work linking actin nematodynamics and endothelial cell mechanics under anisotropic tension, now published in @natphys.nature.com ! rdcu.be/eigWi
@ipparis.bsky.social @polytechniqueparis.bsky.social
@ipparis.bsky.social @polytechniqueparis.bsky.social
Reposted by Michael Riedl
Looking for a student or postdoc!
Want to combine evolutionary analysis + structural modeling with in vitro biochemistry & fluorescence microscopy?
Help us uncover new protein-protein interactions — from in silico to in vitro.
Join us at @istaresearch.bsky.social 👉 looselab.org
🧬💡🔬🎡
Want to combine evolutionary analysis + structural modeling with in vitro biochemistry & fluorescence microscopy?
Help us uncover new protein-protein interactions — from in silico to in vitro.
Join us at @istaresearch.bsky.social 👉 looselab.org
🧬💡🔬🎡
looselab.org
April 10, 2025 at 9:28 AM
Looking for a student or postdoc!
Want to combine evolutionary analysis + structural modeling with in vitro biochemistry & fluorescence microscopy?
Help us uncover new protein-protein interactions — from in silico to in vitro.
Join us at @istaresearch.bsky.social 👉 looselab.org
🧬💡🔬🎡
Want to combine evolutionary analysis + structural modeling with in vitro biochemistry & fluorescence microscopy?
Help us uncover new protein-protein interactions — from in silico to in vitro.
Join us at @istaresearch.bsky.social 👉 looselab.org
🧬💡🔬🎡
Reposted by Michael Riedl
REPOSTING this here just to officially leave "the other place"
Our work on the role of endogenous electric fields in guiding collective cell migration during #morphogenesis is out @naturematerials.bsky.social
nature.com/articles/s41...
Our work on the role of endogenous electric fields in guiding collective cell migration during #morphogenesis is out @naturematerials.bsky.social
nature.com/articles/s41...
Stretch-induced endogenous electric fields drive directed collective cell migration in vivo - Nature Materials
Electric fields guide collective cell migration in developing embryos of Xenopus laevis via a voltage-sensitive phosphatase.
nature.com
April 7, 2025 at 9:46 AM
REPOSTING this here just to officially leave "the other place"
Our work on the role of endogenous electric fields in guiding collective cell migration during #morphogenesis is out @naturematerials.bsky.social
nature.com/articles/s41...
Our work on the role of endogenous electric fields in guiding collective cell migration during #morphogenesis is out @naturematerials.bsky.social
nature.com/articles/s41...
Reposted by Michael Riedl
Very happy that our new paper on social distancing during epidemics has just come out in @pnas.org!
With @molinajohnj.bsky.social, Ryoichi Yamamoto, and Matthew S. Turner.
Understanding Nash epidemics | PNAS www.pnas.org/doi/10.1073/...
With @molinajohnj.bsky.social, Ryoichi Yamamoto, and Matthew S. Turner.
Understanding Nash epidemics | PNAS www.pnas.org/doi/10.1073/...
PNAS
Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...
www.pnas.org
March 12, 2025 at 2:40 AM
Very happy that our new paper on social distancing during epidemics has just come out in @pnas.org!
With @molinajohnj.bsky.social, Ryoichi Yamamoto, and Matthew S. Turner.
Understanding Nash epidemics | PNAS www.pnas.org/doi/10.1073/...
With @molinajohnj.bsky.social, Ryoichi Yamamoto, and Matthew S. Turner.
Understanding Nash epidemics | PNAS www.pnas.org/doi/10.1073/...
Reposted by Michael Riedl
In fun news, a video of mine won the UCLA Broad Stem Cell Research Center's Imaging Competition!
You can see a muscle cell (a myoblast) fusing into a moving myotube. These myotubes mature to become our muscle fibers. They are beautiful cells! 🤩
www.youtube.com/watch?v=g6xK...
You can see a muscle cell (a myoblast) fusing into a moving myotube. These myotubes mature to become our muscle fibers. They are beautiful cells! 🤩
www.youtube.com/watch?v=g6xK...
Muscle cell fusing into a proto-muscle fiber
YouTube video by UCLA Broad Stem Cell Research Center
www.youtube.com
February 12, 2025 at 9:33 PM
In fun news, a video of mine won the UCLA Broad Stem Cell Research Center's Imaging Competition!
You can see a muscle cell (a myoblast) fusing into a moving myotube. These myotubes mature to become our muscle fibers. They are beautiful cells! 🤩
www.youtube.com/watch?v=g6xK...
You can see a muscle cell (a myoblast) fusing into a moving myotube. These myotubes mature to become our muscle fibers. They are beautiful cells! 🤩
www.youtube.com/watch?v=g6xK...
Reposted by Michael Riedl
The Image & Optics Facility @ Institute of Science and Technology Austria is expanding it’s image analysis services and has a vacant position for a service oriented *Image Analysis Specialist* with a strong interest for data infrastructure organization🔬🧑💻📈 - sharing is much appreciated
Job details
Job details
www.ista.ac.at
January 15, 2025 at 5:37 PM
The Image & Optics Facility @ Institute of Science and Technology Austria is expanding it’s image analysis services and has a vacant position for a service oriented *Image Analysis Specialist* with a strong interest for data infrastructure organization🔬🧑💻📈 - sharing is much appreciated
Reposted by Michael Riedl
Excited about protein biochemistry, fluorescence microscopy, and image analysis? Curious how proteins drive bacterial division or define organelle identity? Join us at ISTA! Apply to the PhD program by Jan 8th: gradschool.ist.ac.at
gradschool.ist.ac.at
December 20, 2024 at 9:02 AM
Excited about protein biochemistry, fluorescence microscopy, and image analysis? Curious how proteins drive bacterial division or define organelle identity? Join us at ISTA! Apply to the PhD program by Jan 8th: gradschool.ist.ac.at
Reposted by Michael Riedl
Entropy is one of those formulas that many of us learn, swallow whole, and even use regularly without really understanding.
(E.g., where does that “log” come from? Are there other possible formulas?)
Yet there's an intuitive & almost inevitable way to arrive at this expression.
(E.g., where does that “log” come from? Are there other possible formulas?)
Yet there's an intuitive & almost inevitable way to arrive at this expression.
December 9, 2024 at 10:44 PM
Entropy is one of those formulas that many of us learn, swallow whole, and even use regularly without really understanding.
(E.g., where does that “log” come from? Are there other possible formulas?)
Yet there's an intuitive & almost inevitable way to arrive at this expression.
(E.g., where does that “log” come from? Are there other possible formulas?)
Yet there's an intuitive & almost inevitable way to arrive at this expression.
Reposted by Michael Riedl
New paper out with the Kicheva group by S. Lehr and D. Bruckner! 🧪 Develops a new 2D neural tube organoid, and models its striking self-organized patterns! Key finding: patterning via 2-phase dynamics of BMP, which acts like a temporal relay balancing sequential fate decisions! bit.ly/3OJti4G
December 6, 2024 at 2:46 PM
New paper out with the Kicheva group by S. Lehr and D. Bruckner! 🧪 Develops a new 2D neural tube organoid, and models its striking self-organized patterns! Key finding: patterning via 2-phase dynamics of BMP, which acts like a temporal relay balancing sequential fate decisions! bit.ly/3OJti4G
Reposted by Michael Riedl
As promised, here a fast acquisition of a migrating cell videoed under a microscopy, look those membrane dynamics @ the leading edge !
Bonus: nuclear deformation once the cell rear snaps.
(Fluo nucleus, for the #fluorescencefriday)
@focalplane.bsky.social @cellcommlab.bsky.social #CellMigration 🧪🔬
Bonus: nuclear deformation once the cell rear snaps.
(Fluo nucleus, for the #fluorescencefriday)
@focalplane.bsky.social @cellcommlab.bsky.social #CellMigration 🧪🔬
December 6, 2024 at 8:57 AM
As promised, here a fast acquisition of a migrating cell videoed under a microscopy, look those membrane dynamics @ the leading edge !
Bonus: nuclear deformation once the cell rear snaps.
(Fluo nucleus, for the #fluorescencefriday)
@focalplane.bsky.social @cellcommlab.bsky.social #CellMigration 🧪🔬
Bonus: nuclear deformation once the cell rear snaps.
(Fluo nucleus, for the #fluorescencefriday)
@focalplane.bsky.social @cellcommlab.bsky.social #CellMigration 🧪🔬
Reposted by Michael Riedl
I have moved to 🦋 as well ! Looking forward to reconnecting with old and initiating new science contacts here
Introductory post on 🦋! We're a research group headed by Prof. Johanna Ivaska interested in understanding how integrins contribute to every step of cancer progression. We're located at the Turku Bioscience Center in Turku, Finland! Find out more about us and our interests here: ivaskalab.utu.fi
Ivaska cell adhesion and cancer Lab
Integrins, matrix, motility and mechanotransduction in cancer
ivaskalab.utu.fi
December 2, 2024 at 8:00 AM
I have moved to 🦋 as well ! Looking forward to reconnecting with old and initiating new science contacts here
Reposted by Michael Riedl
Mix two motors of opposite polarity with microtubules and they will partition space !
Microtubules will get organized in polar and active barriers, sorting the two motors in separated domains, leading to the emergence of a new type of patterns.
#morphogenesis
doi.org/10.1073/pnas...
(1/n)
Microtubules will get organized in polar and active barriers, sorting the two motors in separated domains, leading to the emergence of a new type of patterns.
#morphogenesis
doi.org/10.1073/pnas...
(1/n)
November 27, 2024 at 1:42 PM
Mix two motors of opposite polarity with microtubules and they will partition space !
Microtubules will get organized in polar and active barriers, sorting the two motors in separated domains, leading to the emergence of a new type of patterns.
#morphogenesis
doi.org/10.1073/pnas...
(1/n)
Microtubules will get organized in polar and active barriers, sorting the two motors in separated domains, leading to the emergence of a new type of patterns.
#morphogenesis
doi.org/10.1073/pnas...
(1/n)
Reposted by Michael Riedl
🌱🔬The most time-intensive and difficult paper of my PhD is now published in #mSystemsJ! I'm proud of this work and also how much I've grown since I first started this experiment. Read on to learn more about how the functions of bacterial communities impact plant growth and health. 👇
November 25, 2024 at 6:30 PM
🌱🔬The most time-intensive and difficult paper of my PhD is now published in #mSystemsJ! I'm proud of this work and also how much I've grown since I first started this experiment. Read on to learn more about how the functions of bacterial communities impact plant growth and health. 👇
Reposted by Michael Riedl
I thought #fluorescencefriday would be a good opportunity for my first post here. Here are some crazy actin dynamics imaged with TIRF
November 22, 2024 at 12:23 PM
I thought #fluorescencefriday would be a good opportunity for my first post here. Here are some crazy actin dynamics imaged with TIRF
Reposted by Michael Riedl
Before I start posting about newer results on this platform, here is a video from our most recent paper -- www.nature.com/articles/s41...
November 22, 2024 at 4:44 AM
Before I start posting about newer results on this platform, here is a video from our most recent paper -- www.nature.com/articles/s41...
Reposted by Michael Riedl
The cell contacts its chloroplast area by up to 40%! Where does all the material go?
Smart design! Chlorophyll absorbs a lot - what is crucial is not its volume but is a high 2d-projected area for example a network.
Fast contractions are driven via buckling of the network strands into the voids.
Smart design! Chlorophyll absorbs a lot - what is crucial is not its volume but is a high 2d-projected area for example a network.
Fast contractions are driven via buckling of the network strands into the voids.
November 19, 2024 at 9:47 AM
The cell contacts its chloroplast area by up to 40%! Where does all the material go?
Smart design! Chlorophyll absorbs a lot - what is crucial is not its volume but is a high 2d-projected area for example a network.
Fast contractions are driven via buckling of the network strands into the voids.
Smart design! Chlorophyll absorbs a lot - what is crucial is not its volume but is a high 2d-projected area for example a network.
Fast contractions are driven via buckling of the network strands into the voids.
Reposted by Michael Riedl
💥Beyond happy 💥 Our work is now published in PNAS!
www.pnas.org/doi/10.1073/...
With Gloria Canales & @mazi1.bsky.social we studied how the single celled alga Pyrocystis lunula 🌙 move their chloroplast in response to strong light.
Get ready for some fun mechanics, signals and organelle motion! 🧵
www.pnas.org/doi/10.1073/...
With Gloria Canales & @mazi1.bsky.social we studied how the single celled alga Pyrocystis lunula 🌙 move their chloroplast in response to strong light.
Get ready for some fun mechanics, signals and organelle motion! 🧵
November 19, 2024 at 9:47 AM
💥Beyond happy 💥 Our work is now published in PNAS!
www.pnas.org/doi/10.1073/...
With Gloria Canales & @mazi1.bsky.social we studied how the single celled alga Pyrocystis lunula 🌙 move their chloroplast in response to strong light.
Get ready for some fun mechanics, signals and organelle motion! 🧵
www.pnas.org/doi/10.1073/...
With Gloria Canales & @mazi1.bsky.social we studied how the single celled alga Pyrocystis lunula 🌙 move their chloroplast in response to strong light.
Get ready for some fun mechanics, signals and organelle motion! 🧵
Reposted by Michael Riedl
Introductory post on 🦋! We're a research group headed by Prof. Johanna Ivaska interested in understanding how integrins contribute to every step of cancer progression. We're located at the Turku Bioscience Center in Turku, Finland! Find out more about us and our interests here: ivaskalab.utu.fi
Ivaska cell adhesion and cancer Lab
Integrins, matrix, motility and mechanotransduction in cancer
ivaskalab.utu.fi
November 19, 2024 at 2:36 PM
Introductory post on 🦋! We're a research group headed by Prof. Johanna Ivaska interested in understanding how integrins contribute to every step of cancer progression. We're located at the Turku Bioscience Center in Turku, Finland! Find out more about us and our interests here: ivaskalab.utu.fi
We have an inherent intuition for the progression of time. In entropy producing systems the arrow of time should appear clear and a reversed movie feels thereby wrong. Look at these macroscopic active spheres and try to figure out whether the movie has been reversed.(1/6)
arxiv.org/abs/2409.16734
arxiv.org/abs/2409.16734
November 18, 2024 at 5:14 PM
We have an inherent intuition for the progression of time. In entropy producing systems the arrow of time should appear clear and a reversed movie feels thereby wrong. Look at these macroscopic active spheres and try to figure out whether the movie has been reversed.(1/6)
arxiv.org/abs/2409.16734
arxiv.org/abs/2409.16734
Reposted by Michael Riedl
Myoblasts flows on nematics tracks!
November 18, 2024 at 12:39 PM
Myoblasts flows on nematics tracks!
Polymerizing actin creates fireworks that are a sight to behold. This excitable medium produces polymerizing waves similar to those observed in other context. The parallels I tried to lay out in this perspective piece last year: tinyurl.com/53cbxm4v
(LifeAct-GFP in Endothelial Cell)
(LifeAct-GFP in Endothelial Cell)
November 15, 2024 at 4:50 PM