Dinos Meletis
@meletis.bsky.social
neuroscientist at Karolinska Institutet
Pinned
Dinos Meletis
@meletis.bsky.social
· Dec 22
Anxa1+ dopamine neuron vulnerability defines prodromal Parkinson's disease bradykinesia and procedural motor learning impairment
Progressive degeneration of dopamine neurons (DANs) defines Parkinson's disease (PD). However, the identity and function of the most vulnerable DAN populations in prodromal PD remain undefined. Here, ...
www.biorxiv.org
first thing to share here!
excited to share lab’s first study in Parkinson’s disease revealing the prodromal vulnerability and function of the dopamine neuron subtype defined by Anxa1 expression - a specialized system controlling procedural motor learning
www.biorxiv.org/content/10.1...
excited to share lab’s first study in Parkinson’s disease revealing the prodromal vulnerability and function of the dopamine neuron subtype defined by Anxa1 expression - a specialized system controlling procedural motor learning
www.biorxiv.org/content/10.1...
Reposted by Dinos Meletis
🔔 Nominations for the 2026 #ALBA-#FKNE Diversity Prize are now open!
Highlight scientists driving progress in diversity, equity and inclusion in #BrainResearch. 🧠
🗓️ Submit your nominations by 8 January 2026
👉 https://loom.ly/IbLJuVQ
Highlight scientists driving progress in diversity, equity and inclusion in #BrainResearch. 🧠
🗓️ Submit your nominations by 8 January 2026
👉 https://loom.ly/IbLJuVQ
November 14, 2025 at 10:30 AM
🔔 Nominations for the 2026 #ALBA-#FKNE Diversity Prize are now open!
Highlight scientists driving progress in diversity, equity and inclusion in #BrainResearch. 🧠
🗓️ Submit your nominations by 8 January 2026
👉 https://loom.ly/IbLJuVQ
Highlight scientists driving progress in diversity, equity and inclusion in #BrainResearch. 🧠
🗓️ Submit your nominations by 8 January 2026
👉 https://loom.ly/IbLJuVQ
Reposted by Dinos Meletis
The link between the gut #microbiome and autism is not backed by science, researchers say.
Read the full opinion piece in @cp-neuron.bsky.social: spkl.io/63322AbxpA
@wiringthebrain.bsky.social, @statsepi.bsky.social, & @deevybee.bsky.social
Read the full opinion piece in @cp-neuron.bsky.social: spkl.io/63322AbxpA
@wiringthebrain.bsky.social, @statsepi.bsky.social, & @deevybee.bsky.social
November 13, 2025 at 4:00 PM
The link between the gut #microbiome and autism is not backed by science, researchers say.
Read the full opinion piece in @cp-neuron.bsky.social: spkl.io/63322AbxpA
@wiringthebrain.bsky.social, @statsepi.bsky.social, & @deevybee.bsky.social
Read the full opinion piece in @cp-neuron.bsky.social: spkl.io/63322AbxpA
@wiringthebrain.bsky.social, @statsepi.bsky.social, & @deevybee.bsky.social
Reposted by Dinos Meletis
Researchers at KI and @yale.edu have created a multidimensional, molecular map of how the mouse #brain develops after birth and how it reacts to #inflammation. The study is published in @nature.com. 🧪 #neuroscience news.ki.se/scientists-m...
November 6, 2025 at 10:45 AM
Researchers at KI and @yale.edu have created a multidimensional, molecular map of how the mouse #brain develops after birth and how it reacts to #inflammation. The study is published in @nature.com. 🧪 #neuroscience news.ki.se/scientists-m...
Reposted by Dinos Meletis
Wallenberg Scholar Marie Carlén is developing entirely new concepts and methods to analyze the brain’s electrical activity in the hope of elevating our understanding of cognition to a new level #research #science #neuroscience #brain @ki.se @carlenlab.bsky.social
kaw.wallenberg.org/en/research/...
kaw.wallenberg.org/en/research/...
A new map of the brain to reveal our thinking | Knut and Alice Wallenberg Foundation
Research on the structure of the brain has made great strides in recent years. However, Marie Carlén believes a new approach is needed to move forward. She is developing entirely new concepts and meth...
kaw.wallenberg.org
October 31, 2025 at 8:22 AM
Wallenberg Scholar Marie Carlén is developing entirely new concepts and methods to analyze the brain’s electrical activity in the hope of elevating our understanding of cognition to a new level #research #science #neuroscience #brain @ki.se @carlenlab.bsky.social
kaw.wallenberg.org/en/research/...
kaw.wallenberg.org/en/research/...
Reposted by Dinos Meletis
We were thrilled to (mostly) meet in-person last week for the 3rd Annual Symposium of ASAP Collaboration for Team Cragg!
Thank you all for an inspiring meeting of science, sharing and #collaboration. We have built a great momentum, and we are ready for new discoveries in #Parkinsons research!
Thank you all for an inspiring meeting of science, sharing and #collaboration. We have built a great momentum, and we are ready for new discoveries in #Parkinsons research!
October 23, 2025 at 1:30 PM
We were thrilled to (mostly) meet in-person last week for the 3rd Annual Symposium of ASAP Collaboration for Team Cragg!
Thank you all for an inspiring meeting of science, sharing and #collaboration. We have built a great momentum, and we are ready for new discoveries in #Parkinsons research!
Thank you all for an inspiring meeting of science, sharing and #collaboration. We have built a great momentum, and we are ready for new discoveries in #Parkinsons research!
Reposted by Dinos Meletis
New blogpost on my concerns about Wellcome LEAP new $50m program on autism/microbiome links. deevybee.blogspot.com/2025/10/a-le...
#autism #microbiome #biomarkers #diagnostic
#autism #microbiome #biomarkers #diagnostic
A LEAP into the future, or off a cliff: Wellcome LEAP's new $50M program
A few days ago, I saw this post on LinkedIn: How does the gut microbiome shape early brain development? That’s what FORM, a new $50 million...
deevybee.blogspot.com
October 20, 2025 at 1:53 PM
New blogpost on my concerns about Wellcome LEAP new $50m program on autism/microbiome links. deevybee.blogspot.com/2025/10/a-le...
#autism #microbiome #biomarkers #diagnostic
#autism #microbiome #biomarkers #diagnostic
Reposted by Dinos Meletis
During these uncertain times, I’m very happy to see that my institution, @scripps.edu has an open tenure-track Assistant Professor position. Any field in Chemistry or Biology is welcome. I’d especially love to see fellow neuroscientists apply. Please repost!
apply.interfolio.com/174756
apply.interfolio.com/174756
Apply - Interfolio
{{$ctrl.$state.data.pageTitle}} - Apply - Interfolio
apply.interfolio.com
October 14, 2025 at 5:35 PM
During these uncertain times, I’m very happy to see that my institution, @scripps.edu has an open tenure-track Assistant Professor position. Any field in Chemistry or Biology is welcome. I’d especially love to see fellow neuroscientists apply. Please repost!
apply.interfolio.com/174756
apply.interfolio.com/174756
Reposted by Dinos Meletis
The 2025 #NobelPrize in Physiology or Medicine has been awarded to Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi for their groundbreaking discoveries concerning peripheral immune tolerance that prevents the immune system from harming the body 🧪 www.nobelprize.org/prizes/medic...
October 6, 2025 at 9:42 AM
The 2025 #NobelPrize in Physiology or Medicine has been awarded to Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi for their groundbreaking discoveries concerning peripheral immune tolerance that prevents the immune system from harming the body 🧪 www.nobelprize.org/prizes/medic...
Reposted by Dinos Meletis
Postdoc Opportunity at Karolinska Institutet: We're seeking an electrophysiologist to join an exciting collaborative project focusing on diabetes and Parkinson's disease.
Join us!
ki.varbi.com/what:job/job...
Join us!
ki.varbi.com/what:job/job...
Postdoktor i Diabetes och Parkinsons sjukdom
Vill du bidra till medicinsk forskning av toppkvalitet? Det strategiska forskningsprogrammet för diabetes (SRP Diabetes) vid Karolinska Institutet finansierar ett prestigefyllt stipendieprogram för
ki.varbi.com
October 1, 2025 at 5:50 AM
Postdoc Opportunity at Karolinska Institutet: We're seeking an electrophysiologist to join an exciting collaborative project focusing on diabetes and Parkinson's disease.
Join us!
ki.varbi.com/what:job/job...
Join us!
ki.varbi.com/what:job/job...
Reposted by Dinos Meletis
👩🔬👨💻 Postdoc recruitment! 👨🔬👩💻
Join us to use next generation single cell lineage tracing (de Haan & He et al Science 2025) to resolve dermis developmental dynamics & mechanisms.
🚨 Deadline Oct 1st!! 🚨
Please re-post and help us spread the word far and wide! ✈
ki.varbi.com/en/what:job/...
Join us to use next generation single cell lineage tracing (de Haan & He et al Science 2025) to resolve dermis developmental dynamics & mechanisms.
🚨 Deadline Oct 1st!! 🚨
Please re-post and help us spread the word far and wide! ✈
ki.varbi.com/en/what:job/...
Postdoctoral studies in next generation single cell lineage tracing of skin (scholarship)
Do you want to contribute to top quality medical research? A postdoctoral scholarship is available in the lab of Emma R Andersson at the Department of Cell and Molecular Biology, Karolinska Institutet
ki.varbi.com
September 27, 2025 at 7:41 AM
👩🔬👨💻 Postdoc recruitment! 👨🔬👩💻
Join us to use next generation single cell lineage tracing (de Haan & He et al Science 2025) to resolve dermis developmental dynamics & mechanisms.
🚨 Deadline Oct 1st!! 🚨
Please re-post and help us spread the word far and wide! ✈
ki.varbi.com/en/what:job/...
Join us to use next generation single cell lineage tracing (de Haan & He et al Science 2025) to resolve dermis developmental dynamics & mechanisms.
🚨 Deadline Oct 1st!! 🚨
Please re-post and help us spread the word far and wide! ✈
ki.varbi.com/en/what:job/...
very exciting to share the result of a collaborative effort to map the molecular changes in the mouse and human striatum in Parkinson’s, revealing new biological targets and vulnerability of specific cell types with disease progression
A molecular atlas of cell-type specific signatures in the parkinsonian striatum. https://www.biorxiv.org/content/10.1101/2025.09.09.675138v1
September 11, 2025 at 9:26 AM
very exciting to share the result of a collaborative effort to map the molecular changes in the mouse and human striatum in Parkinson’s, revealing new biological targets and vulnerability of specific cell types with disease progression
Reposted by Dinos Meletis
Wrote a eulogy for the yellow letters in my office window. www.thecrimson.com/article/2025...
My Lab Displayed A Message of Solidarity on Our Windows. Harvard Took It Down. | Opinion | The Harvard Crimson
If we continue down this path, we risk not only Harvard’s future as an institution of free inquiry and expression but also its integrity and trustworthiness.
www.thecrimson.com
August 25, 2025 at 10:29 AM
Wrote a eulogy for the yellow letters in my office window. www.thecrimson.com/article/2025...
Reposted by Dinos Meletis
I definitely never regretted the decision to leave New York for Stockholm and Karolinska - now you can join us: big call for assistant professors across medical disciplines coming up. news.ki.se/ki-to-recrui...
KI to recruit junior researchers with a focus on excellence
On 25 June, Karolinska Institutet will be starting a major recruitment drive for 20 junior researchers with a focus on excellence and mobility. As one of Europe’s leading medical universities, KI offe...
news.ki.se
June 19, 2025 at 6:08 AM
I definitely never regretted the decision to leave New York for Stockholm and Karolinska - now you can join us: big call for assistant professors across medical disciplines coming up. news.ki.se/ki-to-recrui...
Reposted by Dinos Meletis
Congratulations to our Human Neural Circuitry team; bit.ly/4dEyX7Z publishes today in Science! This was the hardest challenge of my career, but one of the most rewarding, after years of rebuilding– & expanding my inpatient neuropsychiatry in the service of basic discovery bsky.app/profile/deis...
May 30, 2025 at 5:32 AM
Congratulations to our Human Neural Circuitry team; bit.ly/4dEyX7Z publishes today in Science! This was the hardest challenge of my career, but one of the most rewarding, after years of rebuilding– & expanding my inpatient neuropsychiatry in the service of basic discovery bsky.app/profile/deis...
Reposted by Dinos Meletis
The preliminary program for the 2026 Basal Ganglia Gordon Research Conference is up! www.grc.org/basal-gangli...
Super excited about this program and to move the meeting to Europe for the first time - come join us in Tuscany!
Super excited about this program and to move the meeting to Europe for the first time - come join us in Tuscany!
2026 Basal Ganglia Conference GRC
The 2026 Gordon Research Conference on Basal Ganglia will be held in Lucca (Barga), Lucca Italy. Apply today to reserve your spot.
www.grc.org
April 17, 2025 at 1:23 PM
The preliminary program for the 2026 Basal Ganglia Gordon Research Conference is up! www.grc.org/basal-gangli...
Super excited about this program and to move the meeting to Europe for the first time - come join us in Tuscany!
Super excited about this program and to move the meeting to Europe for the first time - come join us in Tuscany!
most wonderful team 😻
The ASAP CRN 2025 Collaborative Meeting gave us the opportunity to come together in person for an intense, inclusive, and inspiring experience. Always a pleasure to see everyone in person!
@stephcragg.bsky.social
@wademartinslab.bsky.social @meletis.bsky.social @asapresearch.parkinsonsroadmap.org
@stephcragg.bsky.social
@wademartinslab.bsky.social @meletis.bsky.social @asapresearch.parkinsonsroadmap.org
April 16, 2025 at 9:58 PM
most wonderful team 😻
Reposted by Dinos Meletis
New study from the lab is out revisiting old friends/foes #dopamine and #acetylcholine 🧠 @natureneuro.bsky.social ! Congrats and thanks to all the team!
#openscience
@asapresearch.bsky.social @craggasap.bsky.social
@oxforddpag.bsky.social
#openscience
@asapresearch.bsky.social @craggasap.bsky.social
@oxforddpag.bsky.social
🚨 Excited to share our new study in @natureneuro.bsky.social! We (+ @stephcragg.bsky.social) show that ChIs (via nAChRs) continuously, and dynamically DEPRESS dopamine release! @oxforddpag.bsky.social @hls.exeter.ac.uk www.nature.com/articles/s41...
An axonal brake on striatal dopamine output by cholinergic interneurons - Nature Neuroscience
Cholinergic interneurons act at nicotinic receptors to depress dopamine release, interrupting its relationship to dopamine neuron firing and supporting an inverse scaling of dopamine release according...
www.nature.com
March 17, 2025 at 11:07 AM
New study from the lab is out revisiting old friends/foes #dopamine and #acetylcholine 🧠 @natureneuro.bsky.social ! Congrats and thanks to all the team!
#openscience
@asapresearch.bsky.social @craggasap.bsky.social
@oxforddpag.bsky.social
#openscience
@asapresearch.bsky.social @craggasap.bsky.social
@oxforddpag.bsky.social
Reposted by Dinos Meletis
Are you an established (”distinguished”) researcher outside Europe? Thinking of moving here for some reason? Grant opportunity just dropped: www.vr.se/english/appl...
Grant for recruiting international visiting researcher to Sweden
The purpose of the grant is to provide higher education institutions and other research organisations the opportunity to develop and strengthen a research field by recruiting a distinguished researche...
www.vr.se
April 1, 2025 at 7:17 PM
Are you an established (”distinguished”) researcher outside Europe? Thinking of moving here for some reason? Grant opportunity just dropped: www.vr.se/english/appl...
Reposted by Dinos Meletis
A new publication from Cragg Lab is out in @natureneuro.bsky.social revisiting old friends/foes #dopamine and #acetylcholine. Congrats to Yanfeng Zhang, Qinbo Qiao, and the rest of the team on a great paper!
@stephcragg.bsky.social @asapresearch.parkinsonsroadmap.org
#openscience #collaboration
@stephcragg.bsky.social @asapresearch.parkinsonsroadmap.org
#openscience #collaboration
🚨 Excited to share our new study in @natureneuro.bsky.social! We (+ @stephcragg.bsky.social) show that ChIs (via nAChRs) continuously, and dynamically DEPRESS dopamine release! @oxforddpag.bsky.social @hls.exeter.ac.uk www.nature.com/articles/s41...
An axonal brake on striatal dopamine output by cholinergic interneurons - Nature Neuroscience
Cholinergic interneurons act at nicotinic receptors to depress dopamine release, interrupting its relationship to dopamine neuron firing and supporting an inverse scaling of dopamine release according...
www.nature.com
March 31, 2025 at 12:29 PM
A new publication from Cragg Lab is out in @natureneuro.bsky.social revisiting old friends/foes #dopamine and #acetylcholine. Congrats to Yanfeng Zhang, Qinbo Qiao, and the rest of the team on a great paper!
@stephcragg.bsky.social @asapresearch.parkinsonsroadmap.org
#openscience #collaboration
@stephcragg.bsky.social @asapresearch.parkinsonsroadmap.org
#openscience #collaboration
Reposted by Dinos Meletis
Join us this Friday for a webinar on cholinergic interneurons with experts Stephanie Cragg & Mark Howe, hosted by the Swedish Basal Ganglia Society! No registration needed—everyone's welcome! #Neuroscience #Webinar #CholinergicInterneurons 🔗 swebags.ebrains.se/events/choli...
March 27, 2025 at 11:01 AM
Join us this Friday for a webinar on cholinergic interneurons with experts Stephanie Cragg & Mark Howe, hosted by the Swedish Basal Ganglia Society! No registration needed—everyone's welcome! #Neuroscience #Webinar #CholinergicInterneurons 🔗 swebags.ebrains.se/events/choli...
Reposted by Dinos Meletis
The Strategic Research Programme in Diabetes at Karolinska Institutet and Umeå Univeristy is seeking a Programme Manager (based in Stockholm).
More information about the programme is here ki.se/en/srp-diabe...
and the link to the position is here ki.varbi.com/en/what:job/...
Please repost!
More information about the programme is here ki.se/en/srp-diabe...
and the link to the position is here ki.varbi.com/en/what:job/...
Please repost!
March 21, 2025 at 3:23 PM
The Strategic Research Programme in Diabetes at Karolinska Institutet and Umeå Univeristy is seeking a Programme Manager (based in Stockholm).
More information about the programme is here ki.se/en/srp-diabe...
and the link to the position is here ki.varbi.com/en/what:job/...
Please repost!
More information about the programme is here ki.se/en/srp-diabe...
and the link to the position is here ki.varbi.com/en/what:job/...
Please repost!
Reposted by Dinos Meletis
We are hiring a research assistant! Come join our ongoing project investigating the PFC-striatum pathway in cognitive flexibility. Head-fixed behavior, Neuropixels, optogenetics, and viral circuit tracing etc ki.varbi.com/en/what:job/.... Please spread.
Research Assistant in Neuroscience
Do you want to contribute to top quality medical research? The position regards experimental research in the laboratory of Professor Marie Carlén in the Department of Neuroscience. Utilizing a sy
ki.varbi.com
February 24, 2025 at 4:42 AM
We are hiring a research assistant! Come join our ongoing project investigating the PFC-striatum pathway in cognitive flexibility. Head-fixed behavior, Neuropixels, optogenetics, and viral circuit tracing etc ki.varbi.com/en/what:job/.... Please spread.
Reposted by Dinos Meletis
DMC-BrainMap - an open-source, end-to-end tool for multi-feature brain mapping across species https://www.biorxiv.org/content/10.1101/2025.02.19.639009v1
February 22, 2025 at 7:15 AM
DMC-BrainMap - an open-source, end-to-end tool for multi-feature brain mapping across species https://www.biorxiv.org/content/10.1101/2025.02.19.639009v1
Reposted by Dinos Meletis
🧪 We are now accepting LOIs for our Scientific Track funding opportunity through March 20, 2025 (6PM ET).
Your LOI Checklist:
✅ Core Leadership Structure
✅ ECI Requirement
✅ Interdisciplinary Collaboration
✅ Doctoral Degrees
✅ Independent Faculty
Check eligibility & apply: bit.ly/3DXOBxt
Your LOI Checklist:
✅ Core Leadership Structure
✅ ECI Requirement
✅ Interdisciplinary Collaboration
✅ Doctoral Degrees
✅ Independent Faculty
Check eligibility & apply: bit.ly/3DXOBxt
February 20, 2025 at 4:39 PM
🧪 We are now accepting LOIs for our Scientific Track funding opportunity through March 20, 2025 (6PM ET).
Your LOI Checklist:
✅ Core Leadership Structure
✅ ECI Requirement
✅ Interdisciplinary Collaboration
✅ Doctoral Degrees
✅ Independent Faculty
Check eligibility & apply: bit.ly/3DXOBxt
Your LOI Checklist:
✅ Core Leadership Structure
✅ ECI Requirement
✅ Interdisciplinary Collaboration
✅ Doctoral Degrees
✅ Independent Faculty
Check eligibility & apply: bit.ly/3DXOBxt