Marnie Blewitt
@marnieblewitt.bsky.social
Deputy Director at WEHI, Melbourne Australia.
Lab head studying epigenetic control, in the context of X inactivation, genomic imprinting, SMCHD1, Prader Willi Syndrome, FSHD.
Mum, wife, beach lover.
Lab head studying epigenetic control, in the context of X inactivation, genomic imprinting, SMCHD1, Prader Willi Syndrome, FSHD.
Mum, wife, beach lover.
Reposted by Marnie Blewitt
Keen to use an open source workflow for nanobody discovery? Check out Alpseq 🦙
Alpseq’s diversity analysis, enrichment counts & clustering allow different approaches for nanobody selection
Great collab with bioinformaticians @qgouil.bsky.social Kathleen Zeglinski
www.biorxiv.org/content/10.1...
Alpseq’s diversity analysis, enrichment counts & clustering allow different approaches for nanobody selection
Great collab with bioinformaticians @qgouil.bsky.social Kathleen Zeglinski
www.biorxiv.org/content/10.1...
alpseq: an open-source workflow to turbocharge nanobody discovery with high-throughput sequencing
Nanobodies have emerged as promising tools for many biotechnological applications due to their small size, high stability, and remarkable binding specificity. Next-Generation Sequencing (NGS) enables ...
www.biorxiv.org
October 27, 2025 at 3:18 AM
Keen to use an open source workflow for nanobody discovery? Check out Alpseq 🦙
Alpseq’s diversity analysis, enrichment counts & clustering allow different approaches for nanobody selection
Great collab with bioinformaticians @qgouil.bsky.social Kathleen Zeglinski
www.biorxiv.org/content/10.1...
Alpseq’s diversity analysis, enrichment counts & clustering allow different approaches for nanobody selection
Great collab with bioinformaticians @qgouil.bsky.social Kathleen Zeglinski
www.biorxiv.org/content/10.1...
Reposted by Marnie Blewitt
⏳Three days to go until #AusUb2025! What is Grant Dewson most looking forward to in the upcoming Ubiquitin Summit? 🤔 Perhaps the speakers? Perhaps the free coffee ☕️? Or perhaps the very British prospect of cloudy, sunless days at the beach☁️? Watch the video to find out!
November 17, 2025 at 5:07 AM
⏳Three days to go until #AusUb2025! What is Grant Dewson most looking forward to in the upcoming Ubiquitin Summit? 🤔 Perhaps the speakers? Perhaps the free coffee ☕️? Or perhaps the very British prospect of cloudy, sunless days at the beach☁️? Watch the video to find out!
Reposted by Marnie Blewitt
⏳Four days to go until #AusUb2025! Check out the video below to hear some conference tips and tricks from our committee chair David Komander (and some potentially controversial interest rankings!?!?).
More interviews to come in the next few days so watch this space 😉
More interviews to come in the next few days so watch this space 😉
November 16, 2025 at 12:25 PM
⏳Four days to go until #AusUb2025! Check out the video below to hear some conference tips and tricks from our committee chair David Komander (and some potentially controversial interest rankings!?!?).
More interviews to come in the next few days so watch this space 😉
More interviews to come in the next few days so watch this space 😉
Reposted by Marnie Blewitt
Great work from the lab of @jojdavies.bsky.social
Mapping chromatin structure at base-pair resolution unveils a unified model of cis-regulatory element interactions
www.cell.com/cell/fulltex...
Mapping chromatin structure at base-pair resolution unveils a unified model of cis-regulatory element interactions
www.cell.com/cell/fulltex...
Mapping chromatin structure at base-pair resolution unveils a unified model of cis-regulatory element interactions
Li et al. apply base-pair resolution Micro Capture-C ultra to map chromatin contacts
between individual motifs within cis-regulatory elements and reveal a unified model
of biophysically mediated enhan...
www.cell.com
November 17, 2025 at 6:55 AM
Great work from the lab of @jojdavies.bsky.social
Mapping chromatin structure at base-pair resolution unveils a unified model of cis-regulatory element interactions
www.cell.com/cell/fulltex...
Mapping chromatin structure at base-pair resolution unveils a unified model of cis-regulatory element interactions
www.cell.com/cell/fulltex...
Reposted by Marnie Blewitt
The Medical Research Future Fund (MRFF) funds medical research in Australia. Only half the funds have been released. If you're an Australian and able to vote please use the form below to email your local MP to release the full amount of the MRFF
aamri.org.au/mrff/
aamri.org.au/mrff/
Half the Funding. Half the Future. - AAMRI
The Medical Research Future Fund (MRFF) was designed to deliver $1 billion each year in new, lifesaving funding for medical research. We know through financial modelling that the full amount can be re...
aamri.org.au
November 16, 2025 at 9:14 PM
The Medical Research Future Fund (MRFF) funds medical research in Australia. Only half the funds have been released. If you're an Australian and able to vote please use the form below to email your local MP to release the full amount of the MRFF
aamri.org.au/mrff/
aamri.org.au/mrff/
Reposted by Marnie Blewitt
🚨Reposts appreciated‼️If I had read this PhD offer five years ago, I wouldn’t have hesitated for a second to apply 😉
Passionate about gene regulation, chromatin, and developmental biology? Just contact @radaiglesiaslab.bsky.social at @ibbtec.bsky.social 🧬✨
#PhD #3DGenome
Passionate about gene regulation, chromatin, and developmental biology? Just contact @radaiglesiaslab.bsky.social at @ibbtec.bsky.social 🧬✨
#PhD #3DGenome
November 15, 2025 at 9:53 AM
🚨Reposts appreciated‼️If I had read this PhD offer five years ago, I wouldn’t have hesitated for a second to apply 😉
Passionate about gene regulation, chromatin, and developmental biology? Just contact @radaiglesiaslab.bsky.social at @ibbtec.bsky.social 🧬✨
#PhD #3DGenome
Passionate about gene regulation, chromatin, and developmental biology? Just contact @radaiglesiaslab.bsky.social at @ibbtec.bsky.social 🧬✨
#PhD #3DGenome
Reposted by Marnie Blewitt
Last chance! Early bird rates and oral presentation abstract submissions for Lorne Genome 𝐞𝐧𝐝 𝐍𝐨𝐯𝐞𝐦𝐛𝐞𝐫 𝟕𝐭𝐡, 𝟐𝟎𝟐𝟓 - only one week away: https://www.lornegenome.org/registrations
We have a fantastic lineup of national and international speakers: https://www.lornegenome.org/speakers. Join us!
We have a fantastic lineup of national and international speakers: https://www.lornegenome.org/speakers. Join us!
Speakers — Lorne Genome
No description found
www.lornegenome.org
October 30, 2025 at 9:30 PM
Last chance! Early bird rates and oral presentation abstract submissions for Lorne Genome 𝐞𝐧𝐝 𝐍𝐨𝐯𝐞𝐦𝐛𝐞𝐫 𝟕𝐭𝐡, 𝟐𝟎𝟐𝟓 - only one week away: https://www.lornegenome.org/registrations
We have a fantastic lineup of national and international speakers: https://www.lornegenome.org/speakers. Join us!
We have a fantastic lineup of national and international speakers: https://www.lornegenome.org/speakers. Join us!
Reposted by Marnie Blewitt
WEHI stands behind the @aamri.bsky.social campaign to strengthen the sector and secure the future of medical research.
Join the call to release the full MRFF and support our scientists to keep saving lives.
Find out more: www.aamri.org.au/mrff
#releasethefullmrff
Join the call to release the full MRFF and support our scientists to keep saving lives.
Find out more: www.aamri.org.au/mrff
#releasethefullmrff
October 31, 2025 at 12:02 AM
WEHI stands behind the @aamri.bsky.social campaign to strengthen the sector and secure the future of medical research.
Join the call to release the full MRFF and support our scientists to keep saving lives.
Find out more: www.aamri.org.au/mrff
#releasethefullmrff
Join the call to release the full MRFF and support our scientists to keep saving lives.
Find out more: www.aamri.org.au/mrff
#releasethefullmrff
Reposted by Marnie Blewitt
Happy to share our latest publication, in which we show that the arrangement of nucleosomes around CTCF sites contributes to higher-order organisation of chromatin into TADs: www.embopress.org/doi/full/10....
October 27, 2025 at 11:49 AM
Happy to share our latest publication, in which we show that the arrangement of nucleosomes around CTCF sites contributes to higher-order organisation of chromatin into TADs: www.embopress.org/doi/full/10....
Reposted by Marnie Blewitt
If you are a computational biologist come, apply and join Howard & Klose lab in a joint Norwich-Oxford collaboration on chromatin dynamics!
VACANCY - We have an opportunity for a Postdoctoral Researcher to join the Howard Group, working to develop computational models of epigenetic dynamics in the Polycomb system.
www.jic.ac.uk/vacancies/po...
Closing date - 9 November 2025
Salary - £37,500 - £45,350
Contract - 36 months, full-time
www.jic.ac.uk/vacancies/po...
Closing date - 9 November 2025
Salary - £37,500 - £45,350
Contract - 36 months, full-time
Postdoctoral Researcher (Howard Group) | John Innes Centre
An exciting opportunity has arisen for a Postdoctoral Researcher to join the Howard Group at the John Innes Centre, working on cutting-edge science in the field of Computational and Systems Biology.
www.jic.ac.uk
October 8, 2025 at 10:44 AM
If you are a computational biologist come, apply and join Howard & Klose lab in a joint Norwich-Oxford collaboration on chromatin dynamics!
Reposted by Marnie Blewitt
Two group leader positions available in the broader areas of RNA science, RNA technologies, and RNA medicine. Attractive packages and a great environment. Come and join us at Helmholtz RNA Würzburg, Bavaria.
October 8, 2025 at 9:45 PM
Two group leader positions available in the broader areas of RNA science, RNA technologies, and RNA medicine. Attractive packages and a great environment. Come and join us at Helmholtz RNA Würzburg, Bavaria.
Reposted by Marnie Blewitt
📢We're #hiring Group Leaders!
Apply to lead a lab at Janelia & advance biology using theory, computational modeling & machine learning.
🔹5-year renewable appointment
🔹Pioneer new tools & approaches
🔹Collaborate across disciplines
Apply by Nov. 4👉 https://janelia.link/groupleader
Apply to lead a lab at Janelia & advance biology using theory, computational modeling & machine learning.
🔹5-year renewable appointment
🔹Pioneer new tools & approaches
🔹Collaborate across disciplines
Apply by Nov. 4👉 https://janelia.link/groupleader
August 26, 2025 at 7:00 PM
📢We're #hiring Group Leaders!
Apply to lead a lab at Janelia & advance biology using theory, computational modeling & machine learning.
🔹5-year renewable appointment
🔹Pioneer new tools & approaches
🔹Collaborate across disciplines
Apply by Nov. 4👉 https://janelia.link/groupleader
Apply to lead a lab at Janelia & advance biology using theory, computational modeling & machine learning.
🔹5-year renewable appointment
🔹Pioneer new tools & approaches
🔹Collaborate across disciplines
Apply by Nov. 4👉 https://janelia.link/groupleader
Reposted by Marnie Blewitt
We’re expanding our Partner Laboratory Network Steering Committee! 🎉
Thrilled to welcome Lisa Butler, Edwina McGlinn, @ijayas.bsky.social, Amee George, @ryanlister.bsky.social & Denise Doolan to our #leadership team - strengthening national & international collab'n in life sciences.
bit.ly/4gFxzDE
Thrilled to welcome Lisa Butler, Edwina McGlinn, @ijayas.bsky.social, Amee George, @ryanlister.bsky.social & Denise Doolan to our #leadership team - strengthening national & international collab'n in life sciences.
bit.ly/4gFxzDE
EMBL Australia expands Steering Committee to strengthen national collaboration | EMBL Australia
EMBL Australia is pleased to announce the expansion of its Partner Laboratory Network Steering Committee, welcoming new senior representatives from leading research institutions across the country. Th...
bit.ly
September 22, 2025 at 6:06 AM
We’re expanding our Partner Laboratory Network Steering Committee! 🎉
Thrilled to welcome Lisa Butler, Edwina McGlinn, @ijayas.bsky.social, Amee George, @ryanlister.bsky.social & Denise Doolan to our #leadership team - strengthening national & international collab'n in life sciences.
bit.ly/4gFxzDE
Thrilled to welcome Lisa Butler, Edwina McGlinn, @ijayas.bsky.social, Amee George, @ryanlister.bsky.social & Denise Doolan to our #leadership team - strengthening national & international collab'n in life sciences.
bit.ly/4gFxzDE
Reposted by Marnie Blewitt
Functional maps of a genomic locus reveal confinement of an enhancer by its target gene | Science www.science.org/doi/10.1126/...
Functional maps of a genomic locus reveal confinement of an enhancer by its target gene
Genes are often activated by enhancers located at large genomic distances, and the importance of this positioning is poorly understood. By relocating promoter-reporter constructs into thousands of alt...
www.science.org
September 23, 2025 at 9:04 AM
Functional maps of a genomic locus reveal confinement of an enhancer by its target gene | Science www.science.org/doi/10.1126/...
Reposted by Marnie Blewitt
@science.org🧬🔬Kinetic organization of the #genome revealed by ultraresolution multiscale live #imaging | Science www.science.org/doi/10.1126/...
Kinetic organization of the genome revealed by ultraresolution multiscale live imaging
Genome function requires regulated genome motion. However, tools to directly observe this motion in vivo have been limited in coverage and resolution. Here we introduce an approach to tile mammalian c...
www.science.org
September 22, 2025 at 7:43 PM
@science.org🧬🔬Kinetic organization of the #genome revealed by ultraresolution multiscale live #imaging | Science www.science.org/doi/10.1126/...
Reposted by Marnie Blewitt
WEHI researchers have launched a landmark project aimed at closing the cultural gaps in prostate cancer care.
Funded by Movember.
Read the story: www.wehi.edu.au/news/landmar...
Funded by Movember.
Read the story: www.wehi.edu.au/news/landmar...
September 12, 2025 at 12:00 AM
WEHI researchers have launched a landmark project aimed at closing the cultural gaps in prostate cancer care.
Funded by Movember.
Read the story: www.wehi.edu.au/news/landmar...
Funded by Movember.
Read the story: www.wehi.edu.au/news/landmar...
Reposted by Marnie Blewitt
EU and Australia open talks on closer research partnership through Horizon Europe poke @katequinlan.bsky.social @merlincrossley.bsky.social @marnieblewitt.bsky.social @joelpmackay.bsky.social @pseudokinase.bsky.social
www.openaccessgovernment.org/eu-and-austr...
www.openaccessgovernment.org/eu-and-austr...
EU and Australia open talks on closer research partnership through Horizon Europe
The European Commission and the Australian Government have begun discussing their scientific cooperation through Australia’s association with Horizon Europe
www.openaccessgovernment.org
September 11, 2025 at 11:51 AM
EU and Australia open talks on closer research partnership through Horizon Europe poke @katequinlan.bsky.social @merlincrossley.bsky.social @marnieblewitt.bsky.social @joelpmackay.bsky.social @pseudokinase.bsky.social
www.openaccessgovernment.org/eu-and-austr...
www.openaccessgovernment.org/eu-and-austr...
Reposted by Marnie Blewitt
Researchers from WEHI’s Parkinson Disease Research Centre have won the 2025 UNSW Eureka Prize for Scientific Research. The team has been honoured for their research unravelling how PINK1, a key protein linked to early-onset Parkinson’s disease, works.
🔗 www.wehi.edu.au/news/eureka-...
🔗 www.wehi.edu.au/news/eureka-...
September 3, 2025 at 9:54 PM
Researchers from WEHI’s Parkinson Disease Research Centre have won the 2025 UNSW Eureka Prize for Scientific Research. The team has been honoured for their research unravelling how PINK1, a key protein linked to early-onset Parkinson’s disease, works.
🔗 www.wehi.edu.au/news/eureka-...
🔗 www.wehi.edu.au/news/eureka-...
Reposted by Marnie Blewitt
Earlybird registration & abstract submissions now open for the 𝟒𝟕𝐭𝐡 𝐋𝐨𝐫𝐧𝐞 𝐆𝐞𝐧𝐨𝐦𝐞 𝐂𝐨𝐧𝐟𝐞𝐫𝐞𝐧𝐜𝐞, 𝟏𝟓-𝟏𝟖𝐭𝐡 𝐅𝐞𝐛 𝟐𝟎𝟐𝟔: https://www.lornegenome.org/registrations (deadline 7th Nov 2025)
Speakers: https://www.lornegenome.org/speakers
We look forward to seeing you there!
Speakers: https://www.lornegenome.org/speakers
We look forward to seeing you there!
Speakers — Lorne Genome
No description found
www.lornegenome.org
September 3, 2025 at 10:00 PM
Earlybird registration & abstract submissions now open for the 𝟒𝟕𝐭𝐡 𝐋𝐨𝐫𝐧𝐞 𝐆𝐞𝐧𝐨𝐦𝐞 𝐂𝐨𝐧𝐟𝐞𝐫𝐞𝐧𝐜𝐞, 𝟏𝟓-𝟏𝟖𝐭𝐡 𝐅𝐞𝐛 𝟐𝟎𝟐𝟔: https://www.lornegenome.org/registrations (deadline 7th Nov 2025)
Speakers: https://www.lornegenome.org/speakers
We look forward to seeing you there!
Speakers: https://www.lornegenome.org/speakers
We look forward to seeing you there!
Very exciting to see the @wehi-research.bsky.social PINK1 Parkinson’s Disease research team win the Eureka Prize for Scientific Research. Amazing achievement by a brilliant team! @eurekaprizes.bsky.social
September 3, 2025 at 10:00 AM
Very exciting to see the @wehi-research.bsky.social PINK1 Parkinson’s Disease research team win the Eureka Prize for Scientific Research. Amazing achievement by a brilliant team! @eurekaprizes.bsky.social
Reposted by Marnie Blewitt
Very excited to see our latest paper published!
Our paper using Oxford #Nanopore direct RNA sequencing to identify m6A modifications on RNA isoforms in human brain is now out in Science Advances. 🧪
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Isoform-level profiling of m6A epitranscriptomic signatures in human brain
Direct RNA-seq in brain reveals RNA isoform and region-specific m6A modifications, highlighting their role in gene regulation.
www.science.org
August 12, 2025 at 9:52 AM
Very excited to see our latest paper published!
Reposted by Marnie Blewitt
📅 Don’t miss out — register now!
What makes WEHI a great place to study?
Find out at our upcoming A Glimpse into WEHI Student Life in-person event Thursday 14 August, 4:30pm – 6:30pm at Parkville.
To register: www.eventbrite.com.au/e/a-glimpse-...
What makes WEHI a great place to study?
Find out at our upcoming A Glimpse into WEHI Student Life in-person event Thursday 14 August, 4:30pm – 6:30pm at Parkville.
To register: www.eventbrite.com.au/e/a-glimpse-...
August 11, 2025 at 5:48 AM
📅 Don’t miss out — register now!
What makes WEHI a great place to study?
Find out at our upcoming A Glimpse into WEHI Student Life in-person event Thursday 14 August, 4:30pm – 6:30pm at Parkville.
To register: www.eventbrite.com.au/e/a-glimpse-...
What makes WEHI a great place to study?
Find out at our upcoming A Glimpse into WEHI Student Life in-person event Thursday 14 August, 4:30pm – 6:30pm at Parkville.
To register: www.eventbrite.com.au/e/a-glimpse-...
Reposted by Marnie Blewitt
In the most recent episode we talked with @korblab.bsky.social from @upenn.edu about her work on BRD4 and the histone variant H2BE, which influences synaptic genes and neuronal activity. #podcast #epigenetics #chromatin
Listen here: www.activemotif.com/podcasts-eri...
Listen here: www.activemotif.com/podcasts-eri...
August 11, 2025 at 7:00 AM
In the most recent episode we talked with @korblab.bsky.social from @upenn.edu about her work on BRD4 and the histone variant H2BE, which influences synaptic genes and neuronal activity. #podcast #epigenetics #chromatin
Listen here: www.activemotif.com/podcasts-eri...
Listen here: www.activemotif.com/podcasts-eri...
Reposted by Marnie Blewitt
Really beautiful work led by Jessica Leismann in Joan Barau’s lab @imbmainz.bsky.social . If you like elegant mouse genetics, the transposon arms race, and a healthy dose of epigenetics, this one’s for you. www.embopress.org/doi/full/10.... @emboreports.org
DNA methylation at retrotransposons protects the germline by preventing NRF1-mediated activation | EMBO reports
imageimageIn spermatogenesis, loss of promoter DNA methylation reactivates retrotransposons
in patterns shaped by chromatin modifications and the binding of DNA methylation-sensitive
transcription fac...
www.embopress.org
August 6, 2025 at 7:48 PM
Really beautiful work led by Jessica Leismann in Joan Barau’s lab @imbmainz.bsky.social . If you like elegant mouse genetics, the transposon arms race, and a healthy dose of epigenetics, this one’s for you. www.embopress.org/doi/full/10.... @emboreports.org
Reposted by Marnie Blewitt
Cryo-EM of fertilisation complex Pfs230-Pfs48/45 from malaria parasites! 💕💗
🦟 Transgenic parasites without Pfs230 D13D14 do not transmit
🦙 💉Nanobodies + mRNA induced antibodies reduce transmission
New in @Science.org
www.science.org/doi/10.1126/...
#ScienceResearch #Malaria #WEHI
🦟 Transgenic parasites without Pfs230 D13D14 do not transmit
🦙 💉Nanobodies + mRNA induced antibodies reduce transmission
New in @Science.org
www.science.org/doi/10.1126/...
#ScienceResearch #Malaria #WEHI
August 1, 2025 at 12:58 AM
Cryo-EM of fertilisation complex Pfs230-Pfs48/45 from malaria parasites! 💕💗
🦟 Transgenic parasites without Pfs230 D13D14 do not transmit
🦙 💉Nanobodies + mRNA induced antibodies reduce transmission
New in @Science.org
www.science.org/doi/10.1126/...
#ScienceResearch #Malaria #WEHI
🦟 Transgenic parasites without Pfs230 D13D14 do not transmit
🦙 💉Nanobodies + mRNA induced antibodies reduce transmission
New in @Science.org
www.science.org/doi/10.1126/...
#ScienceResearch #Malaria #WEHI