Francesco Cardamone
@francescocardamone.bsky.social
PhD Student at Iovino Lab, Max Planck Institute of Immunobiology and Epigenetics.
Reposted by Francesco Cardamone
🪰 folks! I spoke to the Transmitter about FlyBase. As noted at flybase.org, bridge $ ran out and many staff were laid off.
Good news is stopgap contributions will keep core FlyBase operations active. But community support remains essential. Please donate @FlyBase and share! 1/2
tinyurl.com/FlyBase
Good news is stopgap contributions will keep core FlyBase operations active. But community support remains essential. Please donate @FlyBase and share! 1/2
tinyurl.com/FlyBase
FlyBase secures funding for year, but future still uncertain
The FlyBase team’s fundraising efforts have proven successful in the short term, but restoration of its federal grant remains uncertain.
tinyurl.com
October 29, 2025 at 12:31 PM
🪰 folks! I spoke to the Transmitter about FlyBase. As noted at flybase.org, bridge $ ran out and many staff were laid off.
Good news is stopgap contributions will keep core FlyBase operations active. But community support remains essential. Please donate @FlyBase and share! 1/2
tinyurl.com/FlyBase
Good news is stopgap contributions will keep core FlyBase operations active. But community support remains essential. Please donate @FlyBase and share! 1/2
tinyurl.com/FlyBase
Reposted by Francesco Cardamone
Feeling inspired after presenting some #3Dgenome & #single-cell data at the #EDRC2025 in the beautiful #Alicante🇪🇸🧬🪰
Looking forward to the next amazing sessions to exchange ideas and connect with the community!
Looking forward to the next amazing sessions to exchange ideas and connect with the community!
September 26, 2025 at 7:48 AM
Feeling inspired after presenting some #3Dgenome & #single-cell data at the #EDRC2025 in the beautiful #Alicante🇪🇸🧬🪰
Looking forward to the next amazing sessions to exchange ideas and connect with the community!
Looking forward to the next amazing sessions to exchange ideas and connect with the community!
Functional maps of a genomic locus reveal confinement of an enhancer by its target gene | Science www.science.org/doi/10.1126/...
Functional maps of a genomic locus reveal confinement of an enhancer by its target gene
Genes are often activated by enhancers located at large genomic distances, and the importance of this positioning is poorly understood. By relocating promoter-reporter constructs into thousands of alt...
www.science.org
September 23, 2025 at 9:04 AM
Functional maps of a genomic locus reveal confinement of an enhancer by its target gene | Science www.science.org/doi/10.1126/...
Reposted by Francesco Cardamone
If you like transcription regulation and its mechanisms, this WIP list is for you.
I'm sure I've forgotten lots of people, so don't hesitate to let me know so I can add you to the list.
go.bsky.app/8vTgeXB
I'm sure I've forgotten lots of people, so don't hesitate to let me know so I can add you to the list.
go.bsky.app/8vTgeXB
August 28, 2025 at 12:48 PM
If you like transcription regulation and its mechanisms, this WIP list is for you.
I'm sure I've forgotten lots of people, so don't hesitate to let me know so I can add you to the list.
go.bsky.app/8vTgeXB
I'm sure I've forgotten lots of people, so don't hesitate to let me know so I can add you to the list.
go.bsky.app/8vTgeXB
Reposted by Francesco Cardamone
How bats developed their wings? 🦇
Turns out they reutilize existing gene programs 🔧
Find out more in our paper @natecoevo.nature.com in collaboration with @fany-real.bsky.social and @stemundi.bsky.social labs
www.nature.com/articles/s41...
Turns out they reutilize existing gene programs 🔧
Find out more in our paper @natecoevo.nature.com in collaboration with @fany-real.bsky.social and @stemundi.bsky.social labs
www.nature.com/articles/s41...
Comparative single-cell analyses reveal evolutionary repurposing of a conserved gene programme in bat wing development - Nature Ecology & Evolution
Single-cell comparison of developing bat and mouse limbs reveals conservation of cell populations and gene expression patterns, and suggests repurposing of genes involved in proximal limb development ...
www.nature.com
July 17, 2025 at 1:47 PM
How bats developed their wings? 🦇
Turns out they reutilize existing gene programs 🔧
Find out more in our paper @natecoevo.nature.com in collaboration with @fany-real.bsky.social and @stemundi.bsky.social labs
www.nature.com/articles/s41...
Turns out they reutilize existing gene programs 🔧
Find out more in our paper @natecoevo.nature.com in collaboration with @fany-real.bsky.social and @stemundi.bsky.social labs
www.nature.com/articles/s41...
Reposted by Francesco Cardamone
Our News&views with Germano @cecerelab.bsky.social about the role of H3K27me3 in epigenetic control of piRNA transcription in worms 🪱 and flies 🪰 is out in @natsmb.nature.com
rdcu.be/erkld
rdcu.be/erkld
H3K27me3 expands the epigenetic control of piRNA transcription
Nature Structural & Molecular Biology - Constitutive heterochromatin can promote piRNA transcription, a crucial step in genome defense. Two studies now show that piRNA transcription in...
rdcu.be
June 17, 2025 at 2:17 PM
Our News&views with Germano @cecerelab.bsky.social about the role of H3K27me3 in epigenetic control of piRNA transcription in worms 🪱 and flies 🪰 is out in @natsmb.nature.com
rdcu.be/erkld
rdcu.be/erkld
Reposted by Francesco Cardamone
Textbooks: “Enhancers are just a bunch of TFBSs”
But how do they REALLY work?
New paper with many contributors here @berkeleylab.lbl.gov, @anshulkundaje.bsky.social, @anusri.bsky.social
A 🧵 (1/n)
Free access link: rdcu.be/erD22
But how do they REALLY work?
New paper with many contributors here @berkeleylab.lbl.gov, @anshulkundaje.bsky.social, @anusri.bsky.social
A 🧵 (1/n)
Free access link: rdcu.be/erD22
June 18, 2025 at 5:56 PM
Textbooks: “Enhancers are just a bunch of TFBSs”
But how do they REALLY work?
New paper with many contributors here @berkeleylab.lbl.gov, @anshulkundaje.bsky.social, @anusri.bsky.social
A 🧵 (1/n)
Free access link: rdcu.be/erD22
But how do they REALLY work?
New paper with many contributors here @berkeleylab.lbl.gov, @anshulkundaje.bsky.social, @anusri.bsky.social
A 🧵 (1/n)
Free access link: rdcu.be/erD22
Reposted by Francesco Cardamone
👀 New study: The stability of circular RNAs makes them ideal for long-lasting regulatory tasks in neurons. Researchers from the @hilgerslab.bsky.social have now identified the protein ELAV protein as a master regulator of circular RNA production in the nervous system, crucial for brain function.
Running circles in my head
Researchers in Freiburg have identified the protein ELAV as a key regulator of circular RNA production in the nervous system, which is crucial for brain function.
www.ie-freiburg.mpg.de
June 10, 2025 at 9:29 AM
👀 New study: The stability of circular RNAs makes them ideal for long-lasting regulatory tasks in neurons. Researchers from the @hilgerslab.bsky.social have now identified the protein ELAV protein as a master regulator of circular RNA production in the nervous system, crucial for brain function.
Reposted by Francesco Cardamone
The next TriRhena Gene Regulation Club takes place at the MPI-IE #Freiburg. Save your seat & submit a talk. Strengthen your local #epigenetics network & collaborate with peers.
📅 16 Jun 2025 | 14:00
🎟️ Free entry, registration required
✍️ Register by: 6. Jun
www.ie-freiburg.mpg.de/gene-regulat...
📅 16 Jun 2025 | 14:00
🎟️ Free entry, registration required
✍️ Register by: 6. Jun
www.ie-freiburg.mpg.de/gene-regulat...
May 14, 2025 at 11:41 AM
The next TriRhena Gene Regulation Club takes place at the MPI-IE #Freiburg. Save your seat & submit a talk. Strengthen your local #epigenetics network & collaborate with peers.
📅 16 Jun 2025 | 14:00
🎟️ Free entry, registration required
✍️ Register by: 6. Jun
www.ie-freiburg.mpg.de/gene-regulat...
📅 16 Jun 2025 | 14:00
🎟️ Free entry, registration required
✍️ Register by: 6. Jun
www.ie-freiburg.mpg.de/gene-regulat...
Reposted by Francesco Cardamone
Interested in the latest advancements of #epigenetics of #mammalian early embryogenesis? Then join our upcoming mini-symposium in Freiburg!
📅 April 24, 2025, 14:00-19:00 PM
📌 Max Planck Institute, Freiburg (only on-site!)
🛠️ Organized by: @iovino-lab.bsky.social
Register & join free of charge.
📅 April 24, 2025, 14:00-19:00 PM
📌 Max Planck Institute, Freiburg (only on-site!)
🛠️ Organized by: @iovino-lab.bsky.social
Register & join free of charge.
Symposium: Epigenetics of early mouse development
We are delighted to invite you to to the second symposium, “Epigenetics of Early Mouse Development”, taking place on April 24, 2025, at the Max Planck Institute of Immunobiology and Epigenetics in Fre...
www.ie-freiburg.mpg.de
April 15, 2025 at 7:37 AM
Interested in the latest advancements of #epigenetics of #mammalian early embryogenesis? Then join our upcoming mini-symposium in Freiburg!
📅 April 24, 2025, 14:00-19:00 PM
📌 Max Planck Institute, Freiburg (only on-site!)
🛠️ Organized by: @iovino-lab.bsky.social
Register & join free of charge.
📅 April 24, 2025, 14:00-19:00 PM
📌 Max Planck Institute, Freiburg (only on-site!)
🛠️ Organized by: @iovino-lab.bsky.social
Register & join free of charge.
Reposted by Francesco Cardamone
Exciting news! Our latest work in the Nicola Iovino Lab, “Chromatin landscape at cis-regulatory elements orchestrates cell fate decisions in early embryogenesis,” is now published in Nature Communications!
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Chromatin landscape at cis-regulatory elements orchestrates cell fate decisions in early embryogenesis - Nature Communications
Germ layer specification during zygotic genome activation is regulated by chromatin state. Here, the authors use single-cell multiome profiling in Drosophila to show that H3K27me3 and H3K27ac at cis-r...
www.nature.com
April 14, 2025 at 7:48 PM
Exciting news! Our latest work in the Nicola Iovino Lab, “Chromatin landscape at cis-regulatory elements orchestrates cell fate decisions in early embryogenesis,” is now published in Nature Communications!
www.nature.com/articles/s41...
www.nature.com/articles/s41...
About a week ago, our new story in the #IovinoLab about chromatin factors and germ layer specification during ZGA in Drosophila embryos was published!
Missed it? 🔎 Check out this resume article by our Institute!
#chromatin #epigenetics #development
Missed it? 🔎 Check out this resume article by our Institute!
#chromatin #epigenetics #development
How does a single fertilized egg know how to become muscle, brain, or skin? 🤔
A new study by the @iovino-lab.bsky.social shows how epigenetic mechanisms ensure that the right genes are activated at the right time, allowing each cell to assume its designated role in the body. #drosophila #chromatin
A new study by the @iovino-lab.bsky.social shows how epigenetic mechanisms ensure that the right genes are activated at the right time, allowing each cell to assume its designated role in the body. #drosophila #chromatin
From one to the right
A study by the Max Planck Institute for Immunobiology and Epigenetics investigates how epigenetic mechanisms control early cell differentiation in the embryo. Similar to an orchestra, certain epigenet...
www.ie-freiburg.mpg.de
April 8, 2025 at 8:34 AM
About a week ago, our new story in the #IovinoLab about chromatin factors and germ layer specification during ZGA in Drosophila embryos was published!
Missed it? 🔎 Check out this resume article by our Institute!
#chromatin #epigenetics #development
Missed it? 🔎 Check out this resume article by our Institute!
#chromatin #epigenetics #development
Amazing piece of work from @ninacabezas.bsky.social Lab! Congratulations Jasmin, Mari & team!
New research by the @ninacabezas.bsky.social lab & collaborators from @uniklinik-fr.bsky.social.
A vitamin A metabolite may offer a targeted therapeutic strategy for heart attack patients by regulating HSCs to minimize excessive inflammation and preserve long-term heart function.
A vitamin A metabolite may offer a targeted therapeutic strategy for heart attack patients by regulating HSCs to minimize excessive inflammation and preserve long-term heart function.
Healing a broken heart
A vitamin A metabolite, 4-oxo-retinoic acid, can regulate the activity of hematopoietic stem cells and thereby reduce inflammation after a heart attack, ultimately improving heart function in the long...
www.ie-freiburg.mpg.de
April 2, 2025 at 12:08 PM
Amazing piece of work from @ninacabezas.bsky.social Lab! Congratulations Jasmin, Mari & team!