Janelia Research Campus
@hhmijanelia.bsky.social
HHMI’s Janelia Research Campus in Ashburn, Virginia, is innovating research practices and technologies to solve biology’s deepest mysteries. https://www.janelia.org/
ICYMI: A team of researchers unveiled the complete connectome of an entire male fruit fly central nervous system, encompassing the central brain, optic lobes, and ventral nerve cord. https://hhmi.news/4o3EJnk
Researchers reveal connectome of the male fruit fly central nervous system
A team of researchers at HHMI's Janelia Research Campus has unveiled the complete connectome of a male fruit fly central nervous system—a seamless map of all the neurons in the brain and nerve cord of...
hhmi.news
November 3, 2025 at 4:00 PM
ICYMI: A team of researchers unveiled the complete connectome of an entire male fruit fly central nervous system, encompassing the central brain, optic lobes, and ventral nerve cord. https://hhmi.news/4o3EJnk
Reposted by Janelia Research Campus
A new, nerdy paper. We figured out (some) of the rules underlying cell-permeability of probes and designed ligands that light up, grab, and move proteins around. Awesome @hhmijanelia.bsky.social x @uwmadison.bsky.social x @stjuderesearch.bsky.social collaboration! www.pnas.org/doi/10.1073/...
PNAS
Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...
www.pnas.org
October 27, 2025 at 9:43 PM
A new, nerdy paper. We figured out (some) of the rules underlying cell-permeability of probes and designed ligands that light up, grab, and move proteins around. Awesome @hhmijanelia.bsky.social x @uwmadison.bsky.social x @stjuderesearch.bsky.social collaboration! www.pnas.org/doi/10.1073/...
Join the team at Janelia to use #theory, computation, and modeling to tackle bold questions in #biology. Collaborate across scientific disciplines to drive discovery.
Apply by Nov. 3 @ https://janelia.link/theoryfellowprogram
#computationalbiology #sciencecareers
Apply by Nov. 3 @ https://janelia.link/theoryfellowprogram
#computationalbiology #sciencecareers
October 23, 2025 at 5:00 PM
Join the team at Janelia to use #theory, computation, and modeling to tackle bold questions in #biology. Collaborate across scientific disciplines to drive discovery.
Apply by Nov. 3 @ https://janelia.link/theoryfellowprogram
#computationalbiology #sciencecareers
Apply by Nov. 3 @ https://janelia.link/theoryfellowprogram
#computationalbiology #sciencecareers
Reposted by Janelia Research Campus
Excited to announce our new pre-print (www.biorxiv.org/cgi/content/...)!
This collaborative work (co-led by Adriane Otopalik and Gerry Rubin) examines how neuronal circuits regulate social behaviors, like courtship🫶 and aggression🥊, across sexes. #neuroscience #Drosophila #WomenInSTEM 🧪1/
This collaborative work (co-led by Adriane Otopalik and Gerry Rubin) examines how neuronal circuits regulate social behaviors, like courtship🫶 and aggression🥊, across sexes. #neuroscience #Drosophila #WomenInSTEM 🧪1/
October 23, 2025 at 12:44 PM
Excited to announce our new pre-print (www.biorxiv.org/cgi/content/...)!
This collaborative work (co-led by Adriane Otopalik and Gerry Rubin) examines how neuronal circuits regulate social behaviors, like courtship🫶 and aggression🥊, across sexes. #neuroscience #Drosophila #WomenInSTEM 🧪1/
This collaborative work (co-led by Adriane Otopalik and Gerry Rubin) examines how neuronal circuits regulate social behaviors, like courtship🫶 and aggression🥊, across sexes. #neuroscience #Drosophila #WomenInSTEM 🧪1/
🦠 New research provides a mechanism for understanding how environmental changes to somatic cells are passed through the germline, helping scientists better understand transgenerational effects, like the malnutrition of a parent affecting its offspring. https://hhmi.news/4mCD3QO
October 21, 2025 at 3:00 PM
🦠 New research provides a mechanism for understanding how environmental changes to somatic cells are passed through the germline, helping scientists better understand transgenerational effects, like the malnutrition of a parent affecting its offspring. https://hhmi.news/4mCD3QO
Reposted by Janelia Research Campus
🪰 Srinivas Turaga @hhmijanelia.bsky.social opened #CRSy25 Day 3’s afternoon session with “Simulating the brain and body of the fruit fly”
From detailed connectomes to full-body physics, they model how neural circuits generate flight & walking - bridging the gap between brain structure and behaviour.
From detailed connectomes to full-body physics, they model how neural circuits generate flight & walking - bridging the gap between brain structure and behaviour.
October 17, 2025 at 4:48 PM
🪰 Srinivas Turaga @hhmijanelia.bsky.social opened #CRSy25 Day 3’s afternoon session with “Simulating the brain and body of the fruit fly”
From detailed connectomes to full-body physics, they model how neural circuits generate flight & walking - bridging the gap between brain structure and behaviour.
From detailed connectomes to full-body physics, they model how neural circuits generate flight & walking - bridging the gap between brain structure and behaviour.
🌟 Apply to lead a lab at Janelia 🌟
We’re #hiring Group Leaders in our Computation & Theory research area.
🔹 5-year renewable appointment
🔹 Internal funding + generous resources
🔹 Collaboration across disciplines
📅 Apply by Nov. 4 👉 https://janelia.link/groupleader
We’re #hiring Group Leaders in our Computation & Theory research area.
🔹 5-year renewable appointment
🔹 Internal funding + generous resources
🔹 Collaboration across disciplines
📅 Apply by Nov. 4 👉 https://janelia.link/groupleader
October 16, 2025 at 3:00 PM
🌟 Apply to lead a lab at Janelia 🌟
We’re #hiring Group Leaders in our Computation & Theory research area.
🔹 5-year renewable appointment
🔹 Internal funding + generous resources
🔹 Collaboration across disciplines
📅 Apply by Nov. 4 👉 https://janelia.link/groupleader
We’re #hiring Group Leaders in our Computation & Theory research area.
🔹 5-year renewable appointment
🔹 Internal funding + generous resources
🔹 Collaboration across disciplines
📅 Apply by Nov. 4 👉 https://janelia.link/groupleader
🎉 Congrats to Research Scientist Igor Siwanowicz: 5th & 8th place in the 2025 Nikon Small World Photomicrography Competition for his images of spores of a small tropical fern & mallow pollen germinating on stigma while being parasitized by a filamentous fungus. https://hhmi.news/491e0Uf
October 15, 2025 at 2:42 PM
🎉 Congrats to Research Scientist Igor Siwanowicz: 5th & 8th place in the 2025 Nikon Small World Photomicrography Competition for his images of spores of a small tropical fern & mallow pollen germinating on stigma while being parasitized by a filamentous fungus. https://hhmi.news/491e0Uf
Reposted by Janelia Research Campus
Opening talk: 🧠🐟 How does the whole brain coordinate learning, memory & movement?
@mishaahrens.bsky.social @hhmijanelia.bsky.social unveils whole-brain imaging in zebrafish exploring how neural & body dynamics shape behaviour and adaptation.
@mishaahrens.bsky.social @hhmijanelia.bsky.social unveils whole-brain imaging in zebrafish exploring how neural & body dynamics shape behaviour and adaptation.
October 15, 2025 at 1:42 PM
Opening talk: 🧠🐟 How does the whole brain coordinate learning, memory & movement?
@mishaahrens.bsky.social @hhmijanelia.bsky.social unveils whole-brain imaging in zebrafish exploring how neural & body dynamics shape behaviour and adaptation.
@mishaahrens.bsky.social @hhmijanelia.bsky.social unveils whole-brain imaging in zebrafish exploring how neural & body dynamics shape behaviour and adaptation.
🧞Like its namesake, Janelia’s GENIE Project Team makes wishes come true. Luckily for biologists, this genie doesn’t grant just 3 requests.
🧪Learn about how GENIE has accelerated the development of best-in-class sensors for measuring neuronal activity. https://hhmi.news/4gFqwKX
🧪Learn about how GENIE has accelerated the development of best-in-class sensors for measuring neuronal activity. https://hhmi.news/4gFqwKX
Unleashing the GENIE: Janelia's Project Team develops state-of-the-art sensors for biological research
For more than a decade, the GENIE Project Team at HHMI's Janelia Research Campus has collaborated with the research campus's tool developers and tool users to take innovative biological sensors from novel prototypes to widely used laboratory staples--a ...
hhmi.news
October 14, 2025 at 3:00 PM
🧞Like its namesake, Janelia’s GENIE Project Team makes wishes come true. Luckily for biologists, this genie doesn’t grant just 3 requests.
🧪Learn about how GENIE has accelerated the development of best-in-class sensors for measuring neuronal activity. https://hhmi.news/4gFqwKX
🧪Learn about how GENIE has accelerated the development of best-in-class sensors for measuring neuronal activity. https://hhmi.news/4gFqwKX
🧠 A new wiring diagram of the 166,000+ neurons in the brain & nerve cord of a male fruit fly is a key tool in uncovering how the brain enables complex behavior—information that could ultimately help scientists better understand what causes different diseases ➡️ https://hhmi.news/4o3EJnk
October 13, 2025 at 3:01 PM
🧠 A new wiring diagram of the 166,000+ neurons in the brain & nerve cord of a male fruit fly is a key tool in uncovering how the brain enables complex behavior—information that could ultimately help scientists better understand what causes different diseases ➡️ https://hhmi.news/4o3EJnk
Reposted by Janelia Research Campus
Today marks 4 years of enjoying the beautiful @hhmijanelia.bsky.social campus 🌳
October 12, 2025 at 12:17 AM
Today marks 4 years of enjoying the beautiful @hhmijanelia.bsky.social campus 🌳
📢Apply by Dec. 3 for our joint graduate programs with the Johns Hopkins University School of Medicine in neuroscience & cross-disciplinary biology.
🧠Develop interdisciplinary research projects
🌍Join a collaborative environment
🔬Leverage shared resources & support teams
➡️ janelia.org/graduate
🧠Develop interdisciplinary research projects
🌍Join a collaborative environment
🔬Leverage shared resources & support teams
➡️ janelia.org/graduate
October 9, 2025 at 3:00 PM
📢Apply by Dec. 3 for our joint graduate programs with the Johns Hopkins University School of Medicine in neuroscience & cross-disciplinary biology.
🧠Develop interdisciplinary research projects
🌍Join a collaborative environment
🔬Leverage shared resources & support teams
➡️ janelia.org/graduate
🧠Develop interdisciplinary research projects
🌍Join a collaborative environment
🔬Leverage shared resources & support teams
➡️ janelia.org/graduate
🔊 Listen to Senior Group Leader Hari Shroff discuss microscopy, biology and his path through science in the latest episode of Ashoka University's The Science of It podcast: https://www.youtube.com/watch?v=dyoP5HwAFAc&list=PLaTCrA79FLSx-NV34W0Ee2Ei8FgmBDEKn&index=16
The Science of Microscopy | Innovator Hari Shroff | The Science of It Ep. 4
Microscopist Hari Shroff takes us deeper into the world of nature's tiniest beings in the latest episode of Ashoka University's #TheScienceofIt podcast.
What made a computer scientist and physicist turn to building microscopes to explore the beauty of ...
www.youtube.com
October 7, 2025 at 8:00 PM
🔊 Listen to Senior Group Leader Hari Shroff discuss microscopy, biology and his path through science in the latest episode of Ashoka University's The Science of It podcast: https://www.youtube.com/watch?v=dyoP5HwAFAc&list=PLaTCrA79FLSx-NV34W0Ee2Ei8FgmBDEKn&index=16
Reposted by Janelia Research Campus
Pleased to have this review out in @cp-trendsneuro.bsky.social. In it we discuss various aspects of the intersection between foraging behaviors and neuroscience, and offer some future directions: www.sciencedirect.com/science/arti...
Foraging as an ethological framework for neuroscience
The study of foraging is central to a renewed interest in naturalistic behavior in neuroscience. Applying a foraging framework grounded in behavioral …
www.sciencedirect.com
October 7, 2025 at 12:58 PM
Pleased to have this review out in @cp-trendsneuro.bsky.social. In it we discuss various aspects of the intersection between foraging behaviors and neuroscience, and offer some future directions: www.sciencedirect.com/science/arti...
🪰 A team of researchers has unveiled the complete connectome of a male fruit fly central nervous system—a seamless map of all the neurons in the brain and nerve cord of a single male fruit fly and the millions of connections between them.
🔗 https://hhmi.news/4o3EJnk
🔗 https://hhmi.news/4o3EJnk
October 6, 2025 at 2:16 PM
🪰 A team of researchers has unveiled the complete connectome of a male fruit fly central nervous system—a seamless map of all the neurons in the brain and nerve cord of a single male fruit fly and the millions of connections between them.
🔗 https://hhmi.news/4o3EJnk
🔗 https://hhmi.news/4o3EJnk
Become a Theory Fellow @hhmijanelia.bsky.social
🧪 Work alongside experimentalists to test and refine theories
🎯 Receive mentorship from leading computational scientists
🔁 Contribute to Janelia’s cross-disciplinary research environment
Apply by Nov. 3 @ https://janelia.link/theoryfellowprogram
🧪 Work alongside experimentalists to test and refine theories
🎯 Receive mentorship from leading computational scientists
🔁 Contribute to Janelia’s cross-disciplinary research environment
Apply by Nov. 3 @ https://janelia.link/theoryfellowprogram
October 4, 2025 at 3:00 PM
Become a Theory Fellow @hhmijanelia.bsky.social
🧪 Work alongside experimentalists to test and refine theories
🎯 Receive mentorship from leading computational scientists
🔁 Contribute to Janelia’s cross-disciplinary research environment
Apply by Nov. 3 @ https://janelia.link/theoryfellowprogram
🧪 Work alongside experimentalists to test and refine theories
🎯 Receive mentorship from leading computational scientists
🔁 Contribute to Janelia’s cross-disciplinary research environment
Apply by Nov. 3 @ https://janelia.link/theoryfellowprogram
🥼 New research from the Wang Lab reveals a novel connection between lysosomes & the epigenome and provides new insights into how lysosomes regulate longevity over generations & drive the histone-based transfer of epigenetic information between cells.
🔗 https://hhmi.news/4mCD3QO
🔗 https://hhmi.news/4mCD3QO
October 1, 2025 at 3:00 PM
🥼 New research from the Wang Lab reveals a novel connection between lysosomes & the epigenome and provides new insights into how lysosomes regulate longevity over generations & drive the histone-based transfer of epigenetic information between cells.
🔗 https://hhmi.news/4mCD3QO
🔗 https://hhmi.news/4mCD3QO
Reposted by Janelia Research Campus
Plenary speaker spotlight ✨ Meng Wang (@bcmhouston.bsky.social / @hhmi.org) at #ASBMB26: “Racing the clock: Molecular mechanisms of aging.”
➡️Dive into the biochemical basis of aging, from metabolism to the genome: ow.ly/68i150X37Pm.
#MakeItPossibble #AgingResearch #FutureOfScience
➡️Dive into the biochemical basis of aging, from metabolism to the genome: ow.ly/68i150X37Pm.
#MakeItPossibble #AgingResearch #FutureOfScience
September 27, 2025 at 3:38 AM
Plenary speaker spotlight ✨ Meng Wang (@bcmhouston.bsky.social / @hhmi.org) at #ASBMB26: “Racing the clock: Molecular mechanisms of aging.”
➡️Dive into the biochemical basis of aging, from metabolism to the genome: ow.ly/68i150X37Pm.
#MakeItPossibble #AgingResearch #FutureOfScience
➡️Dive into the biochemical basis of aging, from metabolism to the genome: ow.ly/68i150X37Pm.
#MakeItPossibble #AgingResearch #FutureOfScience
✨ ICYMI: Researchers detail how neurotransmitter receptors in the fly brain change during development ➡️ https://hhmi.news/4mFMhMY
Researchers detail how neurotransmitter receptors in the fly brain change during development
New proteomics research is enabling scientists to decipher how neurotransmitter receptors behave and change as an organism develops. The new work could help scientists better understand the formation and function of synapses--the junctions where communi...
hhmi.news
September 26, 2025 at 3:00 PM
✨ ICYMI: Researchers detail how neurotransmitter receptors in the fly brain change during development ➡️ https://hhmi.news/4mFMhMY
🪱New research from the Wang Lab shows how changes in a worm’s lysosomes promoting longevity are transferred to its offspring through the epigenome, revealing how epigenetic modifications that help organisms cope with environmental stress can be inherited.
🔗 www.janelia.org/news/leaving...
🔗 www.janelia.org/news/leaving...
Leaving a mark: New research shows how longevity is inherited across generations
New research from the Wang Lab reveals a novel connection between lysosomes & the epigenome and provides new insights into how lysosomes regulate longevity over generations & drive the histone-based t...
www.janelia.org
September 25, 2025 at 6:23 PM
🪱New research from the Wang Lab shows how changes in a worm’s lysosomes promoting longevity are transferred to its offspring through the epigenome, revealing how epigenetic modifications that help organisms cope with environmental stress can be inherited.
🔗 www.janelia.org/news/leaving...
🔗 www.janelia.org/news/leaving...
🥼 Working with tool developers & support teams, Janelia’s GENIE Project Team recently created next generation sensors for detecting the neurotransmitters glutamate & GABA and adapted a new tool aimed at controlling & studying specific neural circuits in flies.
🔗 https://hhmi.news/4gFqwKX
🔗 https://hhmi.news/4gFqwKX
September 24, 2025 at 3:05 PM
🥼 Working with tool developers & support teams, Janelia’s GENIE Project Team recently created next generation sensors for detecting the neurotransmitters glutamate & GABA and adapted a new tool aimed at controlling & studying specific neural circuits in flies.
🔗 https://hhmi.news/4gFqwKX
🔗 https://hhmi.news/4gFqwKX
📢 Applications are open for the 4th installment of our ChemTools conference.
We'll explore:
🧪 Platforms & tools for analyzing cell/tissue networks
⚡ Methods to perturb biological networks
🔍 Applications that yield new insights
🛏️ Lodging + meals covered
➡️ Apply by Dec 5: https://janelia.news/CHM26
We'll explore:
🧪 Platforms & tools for analyzing cell/tissue networks
⚡ Methods to perturb biological networks
🔍 Applications that yield new insights
🛏️ Lodging + meals covered
➡️ Apply by Dec 5: https://janelia.news/CHM26
September 19, 2025 at 5:00 PM
📢 Applications are open for the 4th installment of our ChemTools conference.
We'll explore:
🧪 Platforms & tools for analyzing cell/tissue networks
⚡ Methods to perturb biological networks
🔍 Applications that yield new insights
🛏️ Lodging + meals covered
➡️ Apply by Dec 5: https://janelia.news/CHM26
We'll explore:
🧪 Platforms & tools for analyzing cell/tissue networks
⚡ Methods to perturb biological networks
🔍 Applications that yield new insights
🛏️ Lodging + meals covered
➡️ Apply by Dec 5: https://janelia.news/CHM26
Reposted by Janelia Research Campus
We are looking for an #AIEngineer to help build protein language models that capture evolutionary constraints with @matsen.bsky.social and @jbloomlab.bsky.social at #AI@HHMI @hhmijanelia.bsky.social
hhmi.wd1.myworkdayjobs.com/en-US/Extern...
hhmi.wd1.myworkdayjobs.com/en-US/Extern...
AI Engineer - Evolutionary Protein Language Models
Primary Work Address: 19700 Helix Drive, Ashburn, VA, 20147 Current HHMI Employees, click here to apply via your Workday account. Intro: AI@HHMI: HHMI is investing $500 million over the next 10 years ...
hhmi.wd1.myworkdayjobs.com
September 18, 2025 at 4:50 PM
We are looking for an #AIEngineer to help build protein language models that capture evolutionary constraints with @matsen.bsky.social and @jbloomlab.bsky.social at #AI@HHMI @hhmijanelia.bsky.social
hhmi.wd1.myworkdayjobs.com/en-US/Extern...
hhmi.wd1.myworkdayjobs.com/en-US/Extern...
🌟 Launch your own lab at Janelia 🌟
Advance our understanding of biology through theory, computational modeling & machine learning.
🔹 No teaching requirements
🔹 100% internally funded
🔹 Collaborate with expert support teams
📅 Apply by Nov. 4 👉 https://janelia.link/groupleader
Advance our understanding of biology through theory, computational modeling & machine learning.
🔹 No teaching requirements
🔹 100% internally funded
🔹 Collaborate with expert support teams
📅 Apply by Nov. 4 👉 https://janelia.link/groupleader
September 18, 2025 at 3:00 PM
🌟 Launch your own lab at Janelia 🌟
Advance our understanding of biology through theory, computational modeling & machine learning.
🔹 No teaching requirements
🔹 100% internally funded
🔹 Collaborate with expert support teams
📅 Apply by Nov. 4 👉 https://janelia.link/groupleader
Advance our understanding of biology through theory, computational modeling & machine learning.
🔹 No teaching requirements
🔹 100% internally funded
🔹 Collaborate with expert support teams
📅 Apply by Nov. 4 👉 https://janelia.link/groupleader