Keyong Deng
@kdeng.bsky.social
PhD, the department of Clinical Epidemiology, Leiden University Medical Center, the Netherlands.
Working on genetic epidemiology study.
Using Python and R mostly.
Working on genetic epidemiology study.
Using Python and R mostly.
New publication: Effect of colonoscopy screening on risks of colorectal cancer and related death: instrumental variable estimation of per-protocol effects now in the European Journal of Epidemiology
➡️ Read here: link.springer.com/article/10.1...
#cancer #screening #colorectal
➡️ Read here: link.springer.com/article/10.1...
#cancer #screening #colorectal
Effect of colonoscopy screening on risks of colorectal cancer and related death: instrumental variable estimation of per-protocol effects - European Journal of Epidemiology
Background We recently reported per-protocol estimates of colonoscopy screening on colorectal cancer incidence and mortality in NordICC, a large-scale randomized trial. Our results may be affected by ...
link.springer.com
May 25, 2025 at 2:54 PM
Reposted by Keyong Deng
Forever chemicals (PFAS), implicated for many adverse health outcomes, don't have to be forever. They can even be broken down to do something good!
nature.com/articles/d41...
@nature.com
nature.com/articles/d41...
@nature.com
Recovery of fluoride from ‘forever chemicals’ could lead to circular economy for fluorine
Fluoride extracted from waste substances could supplement the waning supply from natural sources.
nature.com
March 26, 2025 at 4:58 PM
Forever chemicals (PFAS), implicated for many adverse health outcomes, don't have to be forever. They can even be broken down to do something good!
nature.com/articles/d41...
@nature.com
nature.com/articles/d41...
@nature.com
Reposted by Keyong Deng
Predicting the risk of developing Alzheimer's disease in the next 10 years with blood biomarkers, such as p-Tau217
www.nature.com/articles/s41... @naturemedicine.bsky.social
www.nature.com/articles/s41... @naturemedicine.bsky.social
March 26, 2025 at 2:27 PM
Predicting the risk of developing Alzheimer's disease in the next 10 years with blood biomarkers, such as p-Tau217
www.nature.com/articles/s41... @naturemedicine.bsky.social
www.nature.com/articles/s41... @naturemedicine.bsky.social
Reposted by Keyong Deng
A full aurora ring over a bay in Iceland
#bluesky #photography #nature #art #landscape #light #travel
#bluesky #photography #nature #art #landscape #light #travel
March 26, 2025 at 3:19 PM
A full aurora ring over a bay in Iceland
#bluesky #photography #nature #art #landscape #light #travel
#bluesky #photography #nature #art #landscape #light #travel
Reposted by Keyong Deng
Nature research paper: MYC ecDNA promotes intratumour heterogeneity and plasticity in PDAC
https://go.nature.com/41IPJwX
https://go.nature.com/41IPJwX
MYC ecDNA promotes intratumour heterogeneity and plasticity in PDAC - Nature
In a model of pancreatic ductal adenocarcinoma, extrachromosomal DNAs are shown to be a source of high-level focal amplification driving MYC heterogeneity and phenotypic adaptation.
go.nature.com
March 12, 2025 at 7:34 PM
Nature research paper: MYC ecDNA promotes intratumour heterogeneity and plasticity in PDAC
https://go.nature.com/41IPJwX
https://go.nature.com/41IPJwX
Reposted by Keyong Deng
1/
If you were taught to test for proportional hazards, talk to your teacher.
The proportional hazards assumption is implausible in most #randomized and #observational studies because the hazard ratios aren't expected to be constant during the follow-up. So "testing" is futile.
But there is more 👇
If you were taught to test for proportional hazards, talk to your teacher.
The proportional hazards assumption is implausible in most #randomized and #observational studies because the hazard ratios aren't expected to be constant during the follow-up. So "testing" is futile.
But there is more 👇
February 3, 2025 at 2:51 PM
1/
If you were taught to test for proportional hazards, talk to your teacher.
The proportional hazards assumption is implausible in most #randomized and #observational studies because the hazard ratios aren't expected to be constant during the follow-up. So "testing" is futile.
But there is more 👇
If you were taught to test for proportional hazards, talk to your teacher.
The proportional hazards assumption is implausible in most #randomized and #observational studies because the hazard ratios aren't expected to be constant during the follow-up. So "testing" is futile.
But there is more 👇
Reposted by Keyong Deng
In people with type 2 #diabetes, sodium-glucose cotransporter 2 (SGLT2) inhibitors and GLP-1 receptor agonists were associated with lower risk of major adverse cardiovascular events.
ja.ma/4jE7Axf
#MedSky
ja.ma/4jE7Axf
#MedSky
February 3, 2025 at 4:27 PM
In people with type 2 #diabetes, sodium-glucose cotransporter 2 (SGLT2) inhibitors and GLP-1 receptor agonists were associated with lower risk of major adverse cardiovascular events.
ja.ma/4jE7Axf
#MedSky
ja.ma/4jE7Axf
#MedSky
Reposted by Keyong Deng
Research in Nature Computational Science shows that large language models exhibit social identity biases similar to humans, having favoritism toward ingroups and hostility toward outgroups. https://go.nature.com/4gjBtku 🧪
December 20, 2024 at 3:22 PM
Research in Nature Computational Science shows that large language models exhibit social identity biases similar to humans, having favoritism toward ingroups and hostility toward outgroups. https://go.nature.com/4gjBtku 🧪
Reposted by Keyong Deng
A study in Scientific Reports finds that both high fruit and high vegetable intake were associated with lower depressive symptoms in people over 45 years old. Only moderate vegetable intakes were associated with lower depressive symptoms. https://go.nature.com/3ZDOIGL 🧪
December 7, 2024 at 3:11 PM
A study in Scientific Reports finds that both high fruit and high vegetable intake were associated with lower depressive symptoms in people over 45 years old. Only moderate vegetable intakes were associated with lower depressive symptoms. https://go.nature.com/3ZDOIGL 🧪
Reposted by Keyong Deng
Using causal diagrams within the Grading of Recommendations, Assessment, Development and Evaluation framework to evaluate confounding adjustment in observational studies - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...
Using causal diagrams within the Grading of Recommendations, Assessment, Development and Evaluation framework to evaluate confounding adjustment in observational studies
The current Grading of Recommendations, Assessment, Development and Evaluation (GRADE)
system instructs appraisers to evaluate whether individual observational studies have
sufficiently adjusted for c...
www.jclinepi.com
December 1, 2024 at 7:12 PM
Using causal diagrams within the Grading of Recommendations, Assessment, Development and Evaluation framework to evaluate confounding adjustment in observational studies - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...
Reposted by Keyong Deng
If you're working with Nightingale Health metabolomics data from UK Biobank, be sure to check out the excellent (and important) work @sritchie73.bsky.social and colleagues have done on its QC and normalisation: www.nature.com/articles/s41...
ukbnmr on CRAN: cran.r-project.org/web/packages...
ukbnmr on CRAN: cran.r-project.org/web/packages...
Quality control and removal of technical variation of NMR metabolic biomarker data in ~120,000 UK Biobank participants - Scientific Data
Scientific Data - Quality control and removal of technical variation of NMR metabolic biomarker data in ~120,000 UK Biobank participants
www.nature.com
December 1, 2024 at 8:01 PM
If you're working with Nightingale Health metabolomics data from UK Biobank, be sure to check out the excellent (and important) work @sritchie73.bsky.social and colleagues have done on its QC and normalisation: www.nature.com/articles/s41...
ukbnmr on CRAN: cran.r-project.org/web/packages...
ukbnmr on CRAN: cran.r-project.org/web/packages...
Reposted by Keyong Deng
Most viewed in the last 7 days from JAMA: Muvalaplin reduced lipoprotein(a) measured using intact lipoprotein(a) and apolipoprotein(a)-based assays and was well tolerated.
https://ja.ma/3CP8Ix0
https://ja.ma/3CP8Ix0
November 30, 2024 at 3:00 PM
Most viewed in the last 7 days from JAMA: Muvalaplin reduced lipoprotein(a) measured using intact lipoprotein(a) and apolipoprotein(a)-based assays and was well tolerated.
https://ja.ma/3CP8Ix0
https://ja.ma/3CP8Ix0
Reposted by Keyong Deng
Over 800 million adults are now living with #diabetes worldwide with more than half not receiving treatment, global analysis suggests.
Explore the findings ▶️ bit.ly/3Be89wl
Explore the findings ▶️ bit.ly/3Be89wl
November 28, 2024 at 12:07 PM
Over 800 million adults are now living with #diabetes worldwide with more than half not receiving treatment, global analysis suggests.
Explore the findings ▶️ bit.ly/3Be89wl
Explore the findings ▶️ bit.ly/3Be89wl
Reposted by Keyong Deng
#KeyConceptSeries: A brief note on the random-effects meta-analysis model and its relationship to other models - @jclinepi.bsky.social
www.jclinepi.com/article/S089...
www.jclinepi.com/article/S089...
A brief note on the random-effects meta-analysis model and its relationship to other models
Meta-analysis is a statistical method for combining quantitative results across studies.
A fundamental decision in undertaking a meta-analysis is choosing an appropriate model
for analysis. This is th...
www.jclinepi.com
November 27, 2024 at 8:13 AM
#KeyConceptSeries: A brief note on the random-effects meta-analysis model and its relationship to other models - @jclinepi.bsky.social
www.jclinepi.com/article/S089...
www.jclinepi.com/article/S089...
Reposted by Keyong Deng
Coffee consumption is associated with the presence and abundance of a specific member of the human gut microbiome, Lawsonibacter asaccharolyticus, and changes to the plasma metabolome, according to a paper in Nature Microbiology. https://go.nature.com/3CIl4as 🧪
November 24, 2024 at 4:08 PM
Coffee consumption is associated with the presence and abundance of a specific member of the human gut microbiome, Lawsonibacter asaccharolyticus, and changes to the plasma metabolome, according to a paper in Nature Microbiology. https://go.nature.com/3CIl4as 🧪