Herranz Lab
@herranzlab.bsky.social
Associate Professor working on Leukemia @rutgerscancer.bsky.social | PharmD @ucm.es | PhD @CNIOStopCancer.bsky.social | Postdoc @columbiauniversity.bsky.social. Posts=my views alone.
Reposted by Herranz Lab
📢Interested in #CancerMetabolism and #leukemia using mouse models in vivo? Come join us!! We're looking for a #postdoc to help us drive one of our multiple currently funded projects! Friends & colleagues, please RT!
👇👇👇
jobs.rutgers.edu/postings/260...
👇👇👇
jobs.rutgers.edu/postings/260...
Postdoctoral Associate
Rutgers, The State University of New Jersey is seeking a Postdoctoral Associate within the Cancer Pharmacology Department at the Rutgers Cancer Institute. In this role, the Postdoctoral Associate will...
jobs.rutgers.edu
October 30, 2025 at 7:23 PM
📢Interested in #CancerMetabolism and #leukemia using mouse models in vivo? Come join us!! We're looking for a #postdoc to help us drive one of our multiple currently funded projects! Friends & colleagues, please RT!
👇👇👇
jobs.rutgers.edu/postings/260...
👇👇👇
jobs.rutgers.edu/postings/260...
Reposted by Herranz Lab
NEW: Trump pardons the husband of GOP Rep. Diana Harshbarger.
Bob Harshbarger pleaded guilty to fraud & distributing kidney drugs from China that weren't FDA approved.
His wife was an officer in the company, but claimed she wasn't involved.
The WH says the pardon was not related to his last name
Bob Harshbarger pleaded guilty to fraud & distributing kidney drugs from China that weren't FDA approved.
His wife was an officer in the company, but claimed she wasn't involved.
The WH says the pardon was not related to his last name
Trump Pardons the Husband of a Republican Congressional Ally
www.nytimes.com
November 11, 2025 at 1:12 AM
NEW: Trump pardons the husband of GOP Rep. Diana Harshbarger.
Bob Harshbarger pleaded guilty to fraud & distributing kidney drugs from China that weren't FDA approved.
His wife was an officer in the company, but claimed she wasn't involved.
The WH says the pardon was not related to his last name
Bob Harshbarger pleaded guilty to fraud & distributing kidney drugs from China that weren't FDA approved.
His wife was an officer in the company, but claimed she wasn't involved.
The WH says the pardon was not related to his last name
Reposted by Herranz Lab
1/New paper from Zheng Wu, Phong Nguyen et al. @cri-utsw.bsky.social shows how cells balance the two pathways that produce purine nucleotides: de novo purine biosynthesis (DNPB) and purine salvage. The surprising mechanism involves NUDT5, a Nudix hydrolase
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
NUDT5 regulates purine metabolism and thiopurine sensitivity by interacting with PPAT
Cells generate purine nucleotides through de novo purine biosynthesis (DNPB) and purine salvage. Purine salvage represses DNPB to prevent excessive purine nucleotide synthesis through mechanisms that ...
www.science.org
November 6, 2025 at 7:01 PM
1/New paper from Zheng Wu, Phong Nguyen et al. @cri-utsw.bsky.social shows how cells balance the two pathways that produce purine nucleotides: de novo purine biosynthesis (DNPB) and purine salvage. The surprising mechanism involves NUDT5, a Nudix hydrolase
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Reposted by Herranz Lab
Always a pleasure collaborating with the Jones Lab. Awesome science and even better people!
Really pleased to share the labs first publication in paediatric T-cell leukaemia. We find that the type 2 diabetes drug canagliflozin possesses anti-leukaemic effects that can be enhanced via dietary restriction of serine.
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Canagliflozin synergises with serine restriction mediating anti-leukaemic effects in T-cell acute lymphoblastic leukaemia
T-cell acute lymphoblastic leukaemia (T-ALL) is a haematological malignancy commonly driven by NOTCH1 activating mutations. A concomitant feature asso…
www.sciencedirect.com
November 5, 2025 at 2:21 PM
Always a pleasure collaborating with the Jones Lab. Awesome science and even better people!
Reposted by Herranz Lab
Ecstatic to share out latest research looking at the role of mitochondrial ABHD11 in controlling T-cell responses. We think this may be a viable target for autoimmunity. Please do give it a read, we would love to hear your thoughts.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Mitochondrial ABHD11 inhibition drives sterol metabolism to modulate T-cell effector function - Nature Communications
α/β-hydrolase domain-containing protein 11 (ABHD11) is a mitochondrial hydrolase, and its expression in CD4 + T-cells has been linked to remission status in rheumatoid arthritis. Here the authors repo...
www.nature.com
November 3, 2025 at 10:20 AM
Ecstatic to share out latest research looking at the role of mitochondrial ABHD11 in controlling T-cell responses. We think this may be a viable target for autoimmunity. Please do give it a read, we would love to hear your thoughts.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
📢Interested in #CancerMetabolism and #leukemia using mouse models in vivo? Come join us!! We're looking for a #postdoc to help us drive one of our multiple currently funded projects! Friends & colleagues, please RT!
👇👇👇
jobs.rutgers.edu/postings/260...
👇👇👇
jobs.rutgers.edu/postings/260...
Postdoctoral Associate
Rutgers, The State University of New Jersey is seeking a Postdoctoral Associate within the Cancer Pharmacology Department at the Rutgers Cancer Institute. In this role, the Postdoctoral Associate will...
jobs.rutgers.edu
October 30, 2025 at 7:23 PM
📢Interested in #CancerMetabolism and #leukemia using mouse models in vivo? Come join us!! We're looking for a #postdoc to help us drive one of our multiple currently funded projects! Friends & colleagues, please RT!
👇👇👇
jobs.rutgers.edu/postings/260...
👇👇👇
jobs.rutgers.edu/postings/260...
Reposted by Herranz Lab
Studies of T cell acute lymphoblastic leukemia reveal that canagliflozin possesses potent anti-leukaemic effects underpinned by proliferative defects, cell cycle disruption and apoptosis, actions synergized by restriction of serine and glycine www.sciencedirect.com/science/arti...
Canagliflozin synergises with serine restriction mediating anti-leukaemic effects in T-cell acute lymphoblastic leukaemia
T-cell acute lymphoblastic leukaemia (T-ALL) is a haematological malignancy commonly driven by NOTCH1 activating mutations. A concomitant feature asso…
www.sciencedirect.com
October 20, 2025 at 7:40 PM
Studies of T cell acute lymphoblastic leukemia reveal that canagliflozin possesses potent anti-leukaemic effects underpinned by proliferative defects, cell cycle disruption and apoptosis, actions synergized by restriction of serine and glycine www.sciencedirect.com/science/arti...
Reposted by Herranz Lab
This is terrible. A brief statement from us:
Congress must stop it. We call for a provision in any CR/budget bill that explicitly declares these Vought shutdown firings to be illegal, null, and void.
Congress must stop it. We call for a provision in any CR/budget bill that explicitly declares these Vought shutdown firings to be illegal, null, and void.
I don’t know who needs to hear this but the CDC is being eviscerated right now. America is not going to have any kind of outbreak response capacity after tonight. Americans’ health data is no longer secure. Say goodbye to federal public health in any capacity. It’s a disaster. We won’t recover.
October 11, 2025 at 1:30 PM
This is terrible. A brief statement from us:
Congress must stop it. We call for a provision in any CR/budget bill that explicitly declares these Vought shutdown firings to be illegal, null, and void.
Congress must stop it. We call for a provision in any CR/budget bill that explicitly declares these Vought shutdown firings to be illegal, null, and void.
Reposted by Herranz Lab
📢Interested in #CancerMetabolism and #leukemia using mouse models in vivo? Come join us!! We're looking for a #postdoc to help us drive one of our multiple currently funded projects! Friends & colleagues, please RT!
👇👇👇
jobs.rutgers.edu/postings/260...
👇👇👇
jobs.rutgers.edu/postings/260...
Rutgers University Employment Opportunities
jobs.rutgers.edu
September 18, 2025 at 2:10 AM
📢Interested in #CancerMetabolism and #leukemia using mouse models in vivo? Come join us!! We're looking for a #postdoc to help us drive one of our multiple currently funded projects! Friends & colleagues, please RT!
👇👇👇
jobs.rutgers.edu/postings/260...
👇👇👇
jobs.rutgers.edu/postings/260...
Reposted by Herranz Lab
This may be the most important paper ever published about NIH funded research.
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
What if NIH had been 40% smaller?
Replaying history with less NIH funding shows widespread impacts on drug-linked research
www.science.org
September 25, 2025 at 9:20 PM
This may be the most important paper ever published about NIH funded research.
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Reposted by Herranz Lab
Link to HHMI preprint mandate hhmicdn.blob.core.windows.net/policies/Imm...
September 24, 2025 at 11:28 PM
Link to HHMI preprint mandate hhmicdn.blob.core.windows.net/policies/Imm...
Reposted by Herranz Lab
Reposted by Herranz Lab
Epigenetic diagnosis of acute leukemia within two hours from sample receipt 🚀
Very happy to share the results of a great collaboration between @hovestadt.bsky.social and Griffin Labs, I co-led with @sbenfatto.bsky.social, published today in @natgenet.nature.com
📄 www.nature.com/articles/s41...
🧵1/n
Very happy to share the results of a great collaboration between @hovestadt.bsky.social and Griffin Labs, I co-led with @sbenfatto.bsky.social, published today in @natgenet.nature.com
📄 www.nature.com/articles/s41...
🧵1/n
Rapid epigenomic classification of acute leukemia - Nature Genetics
The authors present a molecular classification of acute leukemia using 5-methylcytosine signatures, together with a neural network-based classifier for clinical use.
www.nature.com
September 22, 2025 at 8:41 PM
Epigenetic diagnosis of acute leukemia within two hours from sample receipt 🚀
Very happy to share the results of a great collaboration between @hovestadt.bsky.social and Griffin Labs, I co-led with @sbenfatto.bsky.social, published today in @natgenet.nature.com
📄 www.nature.com/articles/s41...
🧵1/n
Very happy to share the results of a great collaboration between @hovestadt.bsky.social and Griffin Labs, I co-led with @sbenfatto.bsky.social, published today in @natgenet.nature.com
📄 www.nature.com/articles/s41...
🧵1/n
Reposted by Herranz Lab
Today, the New York Times published a long essay glorifying Jay Bhattacharya, the Trump NIH director. What?⁉️
Here’s the explanation:
That essay was written by the editor of a Trumpist Republican journal, funded by a Trumpist org that hates science.
SHAME on the Times. 🧪1/
Here’s the explanation:
That essay was written by the editor of a Trumpist Republican journal, funded by a Trumpist org that hates science.
SHAME on the Times. 🧪1/
![us. "151 Writing in National Review, the journal's editor Adam Keiper described The New Atlantis as being written from a "particularly American and conservative way of thinking about both the blessings and the burdens of modern science and technology". 61 New Atlantis authors and bioethicists publishing in other journals have also similarly referred to The New Atlantis as being written from a social conservative stance that
utilizes religion. 71181[9][101](https://cdn.bsky.app/img/feed_thumbnail/plain/did:plc:et2wciooy67fjldjcvls34c6/bafkreif3uz5m4bkojkzfxb33hglbynoebnxdligvronjhvrsazxl4nulpq@jpeg)
September 22, 2025 at 12:00 PM
Today, the New York Times published a long essay glorifying Jay Bhattacharya, the Trump NIH director. What?⁉️
Here’s the explanation:
That essay was written by the editor of a Trumpist Republican journal, funded by a Trumpist org that hates science.
SHAME on the Times. 🧪1/
Here’s the explanation:
That essay was written by the editor of a Trumpist Republican journal, funded by a Trumpist org that hates science.
SHAME on the Times. 🧪1/
📢Interested in #CancerMetabolism and #leukemia using mouse models in vivo? Come join us!! We're looking for a #postdoc to help us drive one of our multiple currently funded projects! Friends & colleagues, please RT!
👇👇👇
jobs.rutgers.edu/postings/260...
👇👇👇
jobs.rutgers.edu/postings/260...
Rutgers University Employment Opportunities
jobs.rutgers.edu
September 18, 2025 at 2:10 AM
📢Interested in #CancerMetabolism and #leukemia using mouse models in vivo? Come join us!! We're looking for a #postdoc to help us drive one of our multiple currently funded projects! Friends & colleagues, please RT!
👇👇👇
jobs.rutgers.edu/postings/260...
👇👇👇
jobs.rutgers.edu/postings/260...
Trump Is Shutting Down the War On Cancer www.nytimes.com/2025/09/14/m...
Trump Is Shutting Down the War On Cancer
www.nytimes.com
September 15, 2025 at 9:00 PM
Trump Is Shutting Down the War On Cancer www.nytimes.com/2025/09/14/m...
Had tons of fun visiting the University of Zurich Children’s Hospital and discussing our science with new and old friends @ninacabezas.bsky.social Thanks so much for the invitation #MorscherLab
September 11, 2025 at 7:54 PM
Had tons of fun visiting the University of Zurich Children’s Hospital and discussing our science with new and old friends @ninacabezas.bsky.social Thanks so much for the invitation #MorscherLab
Reposted by Herranz Lab
Reposted by Herranz Lab
Closing this chapter at @herranzlab.bsky.social! Thanks for all the science, laughs and memories! Miss you already!
September 7, 2025 at 6:51 PM
Closing this chapter at @herranzlab.bsky.social! Thanks for all the science, laughs and memories! Miss you already!
Reposted by Herranz Lab
Wow. Fresh hell delivered by Monday afternoon! This corrupt administration and Supreme Court are really getting efficient with their evil!
Really excited to see what fresh hell this week will bring.
July 14, 2025 at 8:42 PM
Wow. Fresh hell delivered by Monday afternoon! This corrupt administration and Supreme Court are really getting efficient with their evil!
Reposted by Herranz Lab
Summary Table of the massive defunding of biomedical research in the United States
www.nytimes.com/interactive/...
www.nytimes.com/interactive/...
July 6, 2025 at 3:13 PM
Summary Table of the massive defunding of biomedical research in the United States
www.nytimes.com/interactive/...
www.nytimes.com/interactive/...
Reposted by Herranz Lab
Zohran Mamdani won the Democratic primary for mayor of New York City by a 12-point margin, stamping him as the favorite in November. The race was called on Tuesday after officials released a count of ranked-choice ballots. https://trib.al/J0O25nC
July 1, 2025 at 9:00 PM
Zohran Mamdani won the Democratic primary for mayor of New York City by a 12-point margin, stamping him as the favorite in November. The race was called on Tuesday after officials released a count of ranked-choice ballots. https://trib.al/J0O25nC
Reposted by Herranz Lab
People are dying, and many more will in the future because people in charge who, either, don’t understand how the system works, OR, are dead set on destroying it, are crushing every aspect of research, preclinical through clinical. We HAVE to stop these attacks on NIH
www.cbsnews.com/amp/news/whe...
www.cbsnews.com/amp/news/whe...
June 29, 2025 at 3:01 PM
People are dying, and many more will in the future because people in charge who, either, don’t understand how the system works, OR, are dead set on destroying it, are crushing every aspect of research, preclinical through clinical. We HAVE to stop these attacks on NIH
www.cbsnews.com/amp/news/whe...
www.cbsnews.com/amp/news/whe...
Reposted by Herranz Lab
We are dismantling American higher education & scientific research & health care & all the other things to fund concentration camps
If the GOP reconciliation bill passes, ICE gets through FY2029:
- $45 billion for detention, on top of the current annual budget of $3.4 billion
- $14.4 billion for transportation and removal, on top of the current annual budget of $750 million
- $8 billion for hiring/retention
- Billions more.
- $45 billion for detention, on top of the current annual budget of $3.4 billion
- $14.4 billion for transportation and removal, on top of the current annual budget of $750 million
- $8 billion for hiring/retention
- Billions more.
‼️‼️
June 28, 2025 at 10:11 PM
We are dismantling American higher education & scientific research & health care & all the other things to fund concentration camps
