Ksenia Matlawska
@kseniam.bsky.social
Associate Professor at UAB
Studying T-cell leukemia pathology, T-ALL dissemination, CNS/meninges-involved leukemia, microenvironment, inflammation and metabolism
Studying T-cell leukemia pathology, T-ALL dissemination, CNS/meninges-involved leukemia, microenvironment, inflammation and metabolism
Always a pleasure collaborating with the Jones Lab. Awesome science and even better people!
Really pleased to share the labs first publication in paediatric T-cell leukaemia. We find that the type 2 diabetes drug canagliflozin possesses anti-leukaemic effects that can be enhanced via dietary restriction of serine.
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Canagliflozin synergises with serine restriction mediating anti-leukaemic effects in T-cell acute lymphoblastic leukaemia
T-cell acute lymphoblastic leukaemia (T-ALL) is a haematological malignancy commonly driven by NOTCH1 activating mutations. A concomitant feature asso…
www.sciencedirect.com
November 5, 2025 at 2:21 PM
Always a pleasure collaborating with the Jones Lab. Awesome science and even better people!
Reposted by Ksenia Matlawska
Ecstatic to share out latest research looking at the role of mitochondrial ABHD11 in controlling T-cell responses. We think this may be a viable target for autoimmunity. Please do give it a read, we would love to hear your thoughts.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Mitochondrial ABHD11 inhibition drives sterol metabolism to modulate T-cell effector function - Nature Communications
α/β-hydrolase domain-containing protein 11 (ABHD11) is a mitochondrial hydrolase, and its expression in CD4 + T-cells has been linked to remission status in rheumatoid arthritis. Here the authors repo...
www.nature.com
November 3, 2025 at 10:20 AM
Ecstatic to share out latest research looking at the role of mitochondrial ABHD11 in controlling T-cell responses. We think this may be a viable target for autoimmunity. Please do give it a read, we would love to hear your thoughts.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Our fresh and still-steaming Journal of Clinical Investigation preprint is out! 🚀
We explore how T-cell acute lymphoblastic leukemia (T-ALL) exploits inflammatory CXCR3–CXCL10 signaling within the meninges to drive CNS infiltration.
www.jci.org/articles/vie...
We explore how T-cell acute lymphoblastic leukemia (T-ALL) exploits inflammatory CXCR3–CXCL10 signaling within the meninges to drive CNS infiltration.
www.jci.org/articles/vie...
JCI -
T-cell acute lymphoblastic leukemia exploits a neural proinflammatory pathway to colonize the meninges
www.jci.org
October 24, 2025 at 4:24 AM
Our fresh and still-steaming Journal of Clinical Investigation preprint is out! 🚀
We explore how T-cell acute lymphoblastic leukemia (T-ALL) exploits inflammatory CXCR3–CXCL10 signaling within the meninges to drive CNS infiltration.
www.jci.org/articles/vie...
We explore how T-cell acute lymphoblastic leukemia (T-ALL) exploits inflammatory CXCR3–CXCL10 signaling within the meninges to drive CNS infiltration.
www.jci.org/articles/vie...
Reposted by Ksenia Matlawska
Really thrilled to have been involved in this project. It’s an absolute mammoth of a paper looking at the way T-cell leukaemia exploits inflammation to colonise the meninges. Congratulations to Nitesh and @kseniam.bsky.social 🍸
Please give it a read!
www.jci.org/articles/vie...
Please give it a read!
www.jci.org/articles/vie...
JCI -
T-cell acute lymphoblastic leukemia exploits a neural proinflammatory pathway to colonize the meninges
www.jci.org
October 23, 2025 at 5:37 PM
Really thrilled to have been involved in this project. It’s an absolute mammoth of a paper looking at the way T-cell leukaemia exploits inflammation to colonise the meninges. Congratulations to Nitesh and @kseniam.bsky.social 🍸
Please give it a read!
www.jci.org/articles/vie...
Please give it a read!
www.jci.org/articles/vie...
Reposted by Ksenia Matlawska
Really pleased to share the labs first publication in paediatric T-cell leukaemia. We find that the type 2 diabetes drug canagliflozin possesses anti-leukaemic effects that can be enhanced via dietary restriction of serine.
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Canagliflozin synergises with serine restriction mediating anti-leukaemic effects in T-cell acute lymphoblastic leukaemia
T-cell acute lymphoblastic leukaemia (T-ALL) is a haematological malignancy commonly driven by NOTCH1 activating mutations. A concomitant feature asso…
www.sciencedirect.com
October 21, 2025 at 9:37 AM
Really pleased to share the labs first publication in paediatric T-cell leukaemia. We find that the type 2 diabetes drug canagliflozin possesses anti-leukaemic effects that can be enhanced via dietary restriction of serine.
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Reposted by Ksenia Matlawska
The starter pack that all leukemia people were waiting for! This is just a very basic pack, if you want to be included, leave a comment below!
go.bsky.app/EY3k2bE
go.bsky.app/EY3k2bE
November 20, 2024 at 3:17 PM
The starter pack that all leukemia people were waiting for! This is just a very basic pack, if you want to be included, leave a comment below!
go.bsky.app/EY3k2bE
go.bsky.app/EY3k2bE
Reposted by Ksenia Matlawska
So excited to share our work developing a new class of modular synthetic GPCRs, out today @Nature! Check it out nature.com/articles/s41...
December 5, 2024 at 8:10 AM
So excited to share our work developing a new class of modular synthetic GPCRs, out today @Nature! Check it out nature.com/articles/s41...
Reposted by Ksenia Matlawska
🚨 Save the Date!🚨 ISEH is heading to Kumamoto, Japan for #ISEH2025. Check out our confirmed speakers so far and mark your calendars for a great program you won't want to miss ➡️ iseh.org/iseh2025
November 20, 2024 at 10:46 PM
🚨 Save the Date!🚨 ISEH is heading to Kumamoto, Japan for #ISEH2025. Check out our confirmed speakers so far and mark your calendars for a great program you won't want to miss ➡️ iseh.org/iseh2025