Drosophilosopher
@hammedbadmos.bsky.social
PhD. AFHEA. CSO Fellow. Postdoc in @RossCagan lab @CRUK_SI @UofGlasgow #cellbiology #cancerbiology #drosophila #drug #screening #Microscopy #organoids #Python #chemistry
Reposted by Drosophilosopher
A gut-brain axis for aversive interoception drives innate and anticipatory emesis in Drosophila. https://www.biorxiv.org/content/10.1101/2025.10.01.679515v1
October 1, 2025 at 5:15 PM
A gut-brain axis for aversive interoception drives innate and anticipatory emesis in Drosophila. https://www.biorxiv.org/content/10.1101/2025.10.01.679515v1
Reposted by Drosophilosopher
The PhD work of @bboumard.bsky.social officially out in print! Happy to share this issue with our downstairs colleagues in the BDD @frelab.bsky.social @robinjournot.bsky.social
www.cell.com/developmenta...
www.cell.com/developmenta...
Cell-type-specific nucleotide sharing through gap junctions impacts sensitivity to replication stress in Drosophila
Boumard et al. demonstrate gap-junction-dependent tissue-scale nucleotide sharing,
which impacts cellular sensitivity to perturbation of nucleotide homeostasis and replication
stress. Drosophila wing ...
www.cell.com
October 7, 2025 at 6:43 AM
The PhD work of @bboumard.bsky.social officially out in print! Happy to share this issue with our downstairs colleagues in the BDD @frelab.bsky.social @robinjournot.bsky.social
www.cell.com/developmenta...
www.cell.com/developmenta...
Three fantastic keynote lectures to kick off #EDRC2025 Lucia Prieto-Godiño @crick.ac.uk the @embo.org sponsored lecture, Romain Levayer @pasteur.fr and Marta Llimargas @ibmb-csic.bsky.social
September 26, 2025 at 6:17 AM
Reposted by Drosophilosopher
How is developmental speed regulated ? 🪰
Happy to share my PhD story from Schweisguth Lab @devstempasteur.bsky.social. Here we show that cellular NAD+ availability and redox constrain developmental speed in the fly eye.
www.biorxiv.org/content/10.1...
A big thanks to everyone involved!
Happy to share my PhD story from Schweisguth Lab @devstempasteur.bsky.social. Here we show that cellular NAD+ availability and redox constrain developmental speed in the fly eye.
www.biorxiv.org/content/10.1...
A big thanks to everyone involved!
September 22, 2025 at 7:07 PM
How is developmental speed regulated ? 🪰
Happy to share my PhD story from Schweisguth Lab @devstempasteur.bsky.social. Here we show that cellular NAD+ availability and redox constrain developmental speed in the fly eye.
www.biorxiv.org/content/10.1...
A big thanks to everyone involved!
Happy to share my PhD story from Schweisguth Lab @devstempasteur.bsky.social. Here we show that cellular NAD+ availability and redox constrain developmental speed in the fly eye.
www.biorxiv.org/content/10.1...
A big thanks to everyone involved!
Reposted by Drosophilosopher
You’ve heard of ubiquitination, meet deazaguanylation: Doug Wassarman in our lab discovered phage defense pathways have co-opted Q nucleobase biosynthetic enzymes to catalyze a new form of protein conjugation chemistry @science.org
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
September 25, 2025 at 7:16 PM
You’ve heard of ubiquitination, meet deazaguanylation: Doug Wassarman in our lab discovered phage defense pathways have co-opted Q nucleobase biosynthetic enzymes to catalyze a new form of protein conjugation chemistry @science.org
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
#drosophila swarming Alicante beach to celebrate Bruno's birthday #edrc !
September 25, 2025 at 8:00 AM
Reposted by Drosophilosopher
📣 New preprint: Mechanochemical feedback, tissue geometry & rigid-body dynamics initiate rotational migration in Drosophila via spontaneous chiral symmetry breaking. A mechanism generalizable to closed epithelia.
@sreejithsanthosh.bsky.social
biorxiv.org/content/10.1...
@sreejithsanthosh.bsky.social
biorxiv.org/content/10.1...
September 19, 2025 at 6:25 PM
📣 New preprint: Mechanochemical feedback, tissue geometry & rigid-body dynamics initiate rotational migration in Drosophila via spontaneous chiral symmetry breaking. A mechanism generalizable to closed epithelia.
@sreejithsanthosh.bsky.social
biorxiv.org/content/10.1...
@sreejithsanthosh.bsky.social
biorxiv.org/content/10.1...
Reposted by Drosophilosopher
The @fly-eds.bsky.social is having its general assembly this saturday at 13:30 at #EDRC2025 , please join us to discuss our society and to find out more about @flybase.bsky.social and the current funding crisis
September 24, 2025 at 3:23 PM
The @fly-eds.bsky.social is having its general assembly this saturday at 13:30 at #EDRC2025 , please join us to discuss our society and to find out more about @flybase.bsky.social and the current funding crisis
Reposted by Drosophilosopher
Super excited for the European Drosophila Research Conference 2025 in Alicante, Spain. Going to be 4 days of exciting science and lots of fun! My PhD student, Ujjayita will be giving a talk and I have a poster. Pls do drop by! 😊
#Drosophila #EDRC2025
#Drosophila #EDRC2025
Abstract submission is now closed but you can still register to #EDRC2025 until the meeting starts! Looking forward to seeing you all in Alicante!
September 24, 2025 at 12:22 PM
Super excited for the European Drosophila Research Conference 2025 in Alicante, Spain. Going to be 4 days of exciting science and lots of fun! My PhD student, Ujjayita will be giving a talk and I have a poster. Pls do drop by! 😊
#Drosophila #EDRC2025
#Drosophila #EDRC2025
Reposted by Drosophilosopher
We are looking forward to seeing you at the @edrc2025.bsky.social
You can find us
- On Thursday 25th at the workshop: INTERORGAN COMMUNICATION IN THE ERA OF OMICS,
- On Saturday morning 27th @alphyjohn.bsky.social will give a talk in the session stem cells and regeneration
- On poster sessions
You can find us
- On Thursday 25th at the workshop: INTERORGAN COMMUNICATION IN THE ERA OF OMICS,
- On Saturday morning 27th @alphyjohn.bsky.social will give a talk in the session stem cells and regeneration
- On poster sessions
September 22, 2025 at 8:34 AM
We are looking forward to seeing you at the @edrc2025.bsky.social
You can find us
- On Thursday 25th at the workshop: INTERORGAN COMMUNICATION IN THE ERA OF OMICS,
- On Saturday morning 27th @alphyjohn.bsky.social will give a talk in the session stem cells and regeneration
- On poster sessions
You can find us
- On Thursday 25th at the workshop: INTERORGAN COMMUNICATION IN THE ERA OF OMICS,
- On Saturday morning 27th @alphyjohn.bsky.social will give a talk in the session stem cells and regeneration
- On poster sessions
Reposted by Drosophilosopher
@edrc2025.bsky.social almost there! Very much looking forward to meet up and listen to amazing #Drosophila research. Come by my poster (will have the jedi pin on it)
September 23, 2025 at 1:07 PM
@edrc2025.bsky.social almost there! Very much looking forward to meet up and listen to amazing #Drosophila research. Come by my poster (will have the jedi pin on it)
Reposted by Drosophilosopher
Cell and developmental biologists; This is well worth a read: Maik and Roberto synthesize work over decades to propose a provocative model of who mesenchymal cells migrate and shape tissues 🧪 Go for the cool Figures, stay for the deep insights
New perspective in @jcb.org by @maikbischoff.bsky.social & @mayorlab.bsky.social about how mesenchymal cells use contact-dependent rules to generate swarm-like behaviors, patterns & organ forms. rupress.org/jcb/article/...
#CellBio #CellMigration #Morphogenesis #Development #Science
#CellBio #CellMigration #Morphogenesis #Development #Science
September 23, 2025 at 11:04 PM
Cell and developmental biologists; This is well worth a read: Maik and Roberto synthesize work over decades to propose a provocative model of who mesenchymal cells migrate and shape tissues 🧪 Go for the cool Figures, stay for the deep insights
Reposted by Drosophilosopher
I have gotten a bit behind at sharing the lab’s latest work - this paper is now published - check it out! www.cell.com/cell-reports... Long story short: insulin is the major determinant of female fat storage, with a relatively minor effect on males.
September 20, 2025 at 1:39 PM
I have gotten a bit behind at sharing the lab’s latest work - this paper is now published - check it out! www.cell.com/cell-reports... Long story short: insulin is the major determinant of female fat storage, with a relatively minor effect on males.
Reposted by Drosophilosopher
A ring of cells deforms into a triangular keyhole in just 15 minutes. Meet the hindgut, a model for boundary-driven morphogenesis!
Out now in @pnas.org at doi.org/10.1073/pnas... with @zhaoshh.bsky.social, Alex Jacinto, Eric Wieschaus, Stas Shvartsman, @lepuslapis.bsky.social (1/8)
Out now in @pnas.org at doi.org/10.1073/pnas... with @zhaoshh.bsky.social, Alex Jacinto, Eric Wieschaus, Stas Shvartsman, @lepuslapis.bsky.social (1/8)
September 18, 2025 at 8:32 PM
A ring of cells deforms into a triangular keyhole in just 15 minutes. Meet the hindgut, a model for boundary-driven morphogenesis!
Out now in @pnas.org at doi.org/10.1073/pnas... with @zhaoshh.bsky.social, Alex Jacinto, Eric Wieschaus, Stas Shvartsman, @lepuslapis.bsky.social (1/8)
Out now in @pnas.org at doi.org/10.1073/pnas... with @zhaoshh.bsky.social, Alex Jacinto, Eric Wieschaus, Stas Shvartsman, @lepuslapis.bsky.social (1/8)
Reposted by Drosophilosopher
We only had a very minor contribution to this story with Alexis, but definitly worth a reading for those interested by patterning, precision and refinment. Nice combining of quantitative live imaging, modeling and optogenetics to dissect vein patterning dynamics
www.cell.com/developmenta...
www.cell.com/developmenta...
Signaling-dependent refinement of cell fate choice during tissue remodeling in Drosophila pupal wings
Herszterg et al. show that during morphogenesis of the Drosophila pupal wing, a wave
of Notch signaling activity updates cell fates to ensure robust and precise patterning
of wing veins.
www.cell.com
September 19, 2025 at 8:35 AM
We only had a very minor contribution to this story with Alexis, but definitly worth a reading for those interested by patterning, precision and refinment. Nice combining of quantitative live imaging, modeling and optogenetics to dissect vein patterning dynamics
www.cell.com/developmenta...
www.cell.com/developmenta...
Reposted by Drosophilosopher
#Drosophila community - look at this amazing lineup for #InDRC2025
Registration for #InDRC2025 is now open! Visit indrc2025.in to register and submit your abstract.
#genetics #devbio
@flybase.bsky.social
Registration for #InDRC2025 is now open! Visit indrc2025.in to register and submit your abstract.
#genetics #devbio
@flybase.bsky.social
September 19, 2025 at 4:15 AM
#Drosophila community - look at this amazing lineup for #InDRC2025
Registration for #InDRC2025 is now open! Visit indrc2025.in to register and submit your abstract.
#genetics #devbio
@flybase.bsky.social
Registration for #InDRC2025 is now open! Visit indrc2025.in to register and submit your abstract.
#genetics #devbio
@flybase.bsky.social
Reposted by Drosophilosopher
📢Are you a talented #ECR looking to start your independent lab in state-of-the-art cancer research facilities?
Join the CRUK Scotland Institute & @uofgcancersciences.bsky.social as a Junior Group Leader!
👉Apply here: www.crukscotlandinstitute.ac.uk/careers/grou...
📅Closing date: 10 October 2025
Join the CRUK Scotland Institute & @uofgcancersciences.bsky.social as a Junior Group Leader!
👉Apply here: www.crukscotlandinstitute.ac.uk/careers/grou...
📅Closing date: 10 October 2025
September 15, 2025 at 3:41 PM
📢Are you a talented #ECR looking to start your independent lab in state-of-the-art cancer research facilities?
Join the CRUK Scotland Institute & @uofgcancersciences.bsky.social as a Junior Group Leader!
👉Apply here: www.crukscotlandinstitute.ac.uk/careers/grou...
📅Closing date: 10 October 2025
Join the CRUK Scotland Institute & @uofgcancersciences.bsky.social as a Junior Group Leader!
👉Apply here: www.crukscotlandinstitute.ac.uk/careers/grou...
📅Closing date: 10 October 2025
Reposted by Drosophilosopher
This paper nicely supports our microtubule-curling-based model in neurons! See an easy read here: doi.org/10.1177/1755... (OA: tinyurl.com/5dysx3d3)
September 15, 2025 at 10:19 AM
This paper nicely supports our microtubule-curling-based model in neurons! See an easy read here: doi.org/10.1177/1755... (OA: tinyurl.com/5dysx3d3)
Reposted by Drosophilosopher
Our work on germline stem cell cytonemes and BMP signalling is finally published! A great team effort from the Ashe lab, @wilcocksonscott.bsky.social and @shukryjhabib.bsky.social.
www.pnas.org/doi/epdf/10....
www.pnas.org/doi/epdf/10....
Ovarian germline stem cell dedifferentiation is cytoneme dependent
www.pnas.org
September 14, 2025 at 2:08 PM
Our work on germline stem cell cytonemes and BMP signalling is finally published! A great team effort from the Ashe lab, @wilcocksonscott.bsky.social and @shukryjhabib.bsky.social.
www.pnas.org/doi/epdf/10....
www.pnas.org/doi/epdf/10....
Reposted by Drosophilosopher
We are hiring! The University of Illinois Urbana-Champaign Department of Cell and Developmental Biology is hiring a faculty member in the area of Aging, broadly defined. Come join us! Deadline is soon! www.nature.com/naturecareer...
Assistant or Associate Professor - Urbana, Illinois job with University of Illinois, School of Molecular and Cellular Biology | 12843703
Tenure-track Assistant or Associate Professor Department of Cell and Developmental Biology School of Molecular and Cellular Biology University of I...
www.nature.com
September 15, 2025 at 2:31 PM
We are hiring! The University of Illinois Urbana-Champaign Department of Cell and Developmental Biology is hiring a faculty member in the area of Aging, broadly defined. Come join us! Deadline is soon! www.nature.com/naturecareer...
Reposted by Drosophilosopher
Epithelial crowding drives membrane depolarisation by ENaC/Na+ entry which triggers rapid volume loss, piezo activation and live cell extrusion. Importantly, low intracellular ATP primes cells for live extrusion by preventing the restoring of mb polarisation.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Energy deficiency selects crowded live epithelial cells for extrusion - Nature
Crowded epithelial cells with the least energy and membrane potential are selected for extrusion.
www.nature.com
September 15, 2025 at 1:52 PM
Epithelial crowding drives membrane depolarisation by ENaC/Na+ entry which triggers rapid volume loss, piezo activation and live cell extrusion. Importantly, low intracellular ATP primes cells for live extrusion by preventing the restoring of mb polarisation.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Drosophilosopher
If you are interested in the latest advances in Imaging Cell Dynamics, check out the 2026 @jcellsci.bsky.social Meeting. These small meetings are a terrific way to meet key people in the field and get feedback on your own work. Highly recommended!
www.biologists.com/meetings/jcs...
www.biologists.com/meetings/jcs...
September 15, 2025 at 4:31 PM
If you are interested in the latest advances in Imaging Cell Dynamics, check out the 2026 @jcellsci.bsky.social Meeting. These small meetings are a terrific way to meet key people in the field and get feedback on your own work. Highly recommended!
www.biologists.com/meetings/jcs...
www.biologists.com/meetings/jcs...
Reposted by Drosophilosopher
Garibagaoglu, R., Kobayashi, R., Hanashiro, V., Tomita, J., Kume, K. (2025). The effect of L-alanine on sleep through taste properties in #Drosophila melanogaster. Neurosci Res, 218:104924 www.sciencedirect.com/science/arti...
The effect of L-alanine on sleep through taste properties in Drosophila melanogaster
Sleep and nutrition are important for the survival of organisms. This study focuses on the effects of amino acids, specifically L-alanine, on sleep of…
www.sciencedirect.com
September 10, 2025 at 12:23 AM
Garibagaoglu, R., Kobayashi, R., Hanashiro, V., Tomita, J., Kume, K. (2025). The effect of L-alanine on sleep through taste properties in #Drosophila melanogaster. Neurosci Res, 218:104924 www.sciencedirect.com/science/arti...