Elizabeth Rideout
@ejrideout.bsky.social
My lab studies sex differences in metabolism and metabolic disease in flies and mice. #sexdifferences #Drosophila #lipid #insulin #betacell
Reposted by Elizabeth Rideout
🪰 folks! I spoke to the Transmitter about FlyBase. As noted at flybase.org, bridge $ ran out and many staff were laid off.
Good news is stopgap contributions will keep core FlyBase operations active. But community support remains essential. Please donate @FlyBase and share! 1/2
tinyurl.com/FlyBase
Good news is stopgap contributions will keep core FlyBase operations active. But community support remains essential. Please donate @FlyBase and share! 1/2
tinyurl.com/FlyBase
FlyBase secures funding for year, but future still uncertain
The FlyBase team’s fundraising efforts have proven successful in the short term, but restoration of its federal grant remains uncertain.
tinyurl.com
October 29, 2025 at 12:31 PM
🪰 folks! I spoke to the Transmitter about FlyBase. As noted at flybase.org, bridge $ ran out and many staff were laid off.
Good news is stopgap contributions will keep core FlyBase operations active. But community support remains essential. Please donate @FlyBase and share! 1/2
tinyurl.com/FlyBase
Good news is stopgap contributions will keep core FlyBase operations active. But community support remains essential. Please donate @FlyBase and share! 1/2
tinyurl.com/FlyBase
Reposted by Elizabeth Rideout
📣Tomorrow is International #DayoftheGirl
& 30 years since the Beijing Declaration on advancing equity, development & peace for all women & girls
📈We must scale investment in girls — including through research, health, education & empowerment-
-a commitment we make in our lab
#GenerationEquality
& 30 years since the Beijing Declaration on advancing equity, development & peace for all women & girls
📈We must scale investment in girls — including through research, health, education & empowerment-
-a commitment we make in our lab
#GenerationEquality
October 10, 2025 at 1:08 PM
📣Tomorrow is International #DayoftheGirl
& 30 years since the Beijing Declaration on advancing equity, development & peace for all women & girls
📈We must scale investment in girls — including through research, health, education & empowerment-
-a commitment we make in our lab
#GenerationEquality
& 30 years since the Beijing Declaration on advancing equity, development & peace for all women & girls
📈We must scale investment in girls — including through research, health, education & empowerment-
-a commitment we make in our lab
#GenerationEquality
Reposted by Elizabeth Rideout
Burgmer, S., Meyer Zu Altenschildesche, F., Gyenis, A., Lee, H., Vilchez, D., Giavalisco, P., Fichant, A., Uhlirova, M., Storelli, G. (2025). Endosymbiont control through non-canonical immune signaling and gut metabolic remodeling. Cell Rep, 44(6):115811 www.cell.com/cell-reports...
Endosymbiont control through non-canonical immune signaling and gut metabolic remodeling
Burgmer et al. show that the pattern recognition receptors (PRRs) PGRP-LC and PGRP-LE
repress key metabolic functions in the Drosophila midgut. These regulations occur
independently of canonical immun...
www.cell.com
October 6, 2025 at 10:39 PM
Burgmer, S., Meyer Zu Altenschildesche, F., Gyenis, A., Lee, H., Vilchez, D., Giavalisco, P., Fichant, A., Uhlirova, M., Storelli, G. (2025). Endosymbiont control through non-canonical immune signaling and gut metabolic remodeling. Cell Rep, 44(6):115811 www.cell.com/cell-reports...
Another amazing achievement from the fly community 🤩
Exciting news for #drosophila #connectomics and #neuroscience enthusiasts: the Drosophila male central nervous system connectome is now live for exploration. Find out more at the landing page hosted by our Janelia FlyEM collaborators www.janelia.org/project-team....
Male CNS Connectome
A team of researchers has unveiled the complete connectome of a male fruit fly central nervous system —a seamless map of all the neurons in the brain and nerve cord of a single male fruit fly and the ...
www.janelia.org
October 6, 2025 at 1:23 AM
Another amazing achievement from the fly community 🤩
Reposted by Elizabeth Rideout
💫NEW: @telemanlab.bsky.social & co demonstrate that #AMPK can be activated by signaling metabolite, #adenosine, under non-stress conditions during #Drosophila development. The intestine regulates adenosine levels, thus, remotely controlling wing disc AMPK activation and growth.
bit.ly/4gX6njF
bit.ly/4gX6njF
Remote control of AMPK via extracellular adenosine controls tissue growth - Nature Cell Biology
Zhang et al. demonstrate that AMPK can be activated by signalling metabolite, adenosine, under non-stress conditions during Drosophila development. The intestine regulates adenosine levels, thus, remotely controlling wing disc AMPK activation and growth.
bit.ly
October 4, 2025 at 2:32 PM
💫NEW: @telemanlab.bsky.social & co demonstrate that #AMPK can be activated by signaling metabolite, #adenosine, under non-stress conditions during #Drosophila development. The intestine regulates adenosine levels, thus, remotely controlling wing disc AMPK activation and growth.
bit.ly/4gX6njF
bit.ly/4gX6njF
Reposted by Elizabeth Rideout
🪰 More than 750 scientists from 40+ countries gathered in Alicante for the XXVIII European Drosophila Research Conference #EDRC2025.
For 4 days, the fruit fly took center stage as a model to study health, aging, and disease👏
@edrc2025.bsky.social
@csic.es @dicv.csic.es @umh.es
For 4 days, the fruit fly took center stage as a model to study health, aging, and disease👏
@edrc2025.bsky.social
@csic.es @dicv.csic.es @umh.es
September 29, 2025 at 4:57 PM
🪰 More than 750 scientists from 40+ countries gathered in Alicante for the XXVIII European Drosophila Research Conference #EDRC2025.
For 4 days, the fruit fly took center stage as a model to study health, aging, and disease👏
@edrc2025.bsky.social
@csic.es @dicv.csic.es @umh.es
For 4 days, the fruit fly took center stage as a model to study health, aging, and disease👏
@edrc2025.bsky.social
@csic.es @dicv.csic.es @umh.es
Reposted by Elizabeth Rideout
Thank you to all #EDRC2025 participants and a big applause to the organizing committee for this great #Drosophila meeting! See you all in Bonn for #EDRC2027
September 28, 2025 at 4:00 PM
Thank you to all #EDRC2025 participants and a big applause to the organizing committee for this great #Drosophila meeting! See you all in Bonn for #EDRC2027
Reposted by Elizabeth Rideout
#edrc2025 European #drosophila Society meeting announces the 2029 meeting location : see you all in Szeged (and Bonn in 2027 of course)!
September 27, 2025 at 11:46 AM
#edrc2025 European #drosophila Society meeting announces the 2029 meeting location : see you all in Szeged (and Bonn in 2027 of course)!
Beautiful location, fabulous science, and wonderful people 🤩 Thanks to the organizers for all your hard work in bringing us together!
We are on day 3 of #EDRC2025 continuing with excellent #Drosophila science
September 28, 2025 at 7:30 AM
Beautiful location, fabulous science, and wonderful people 🤩 Thanks to the organizers for all your hard work in bringing us together!
Reposted by Elizabeth Rideout
Interesting episode of short wave about the origin of endometriosis. I really appreciate that they end with how uncertainty in NIH funding affects the future of their work.
www.npr.org/2025/09/26/n...
www.npr.org/2025/09/26/n...
What causes endometriosis? Scientists are closer to finding out : Short Wave
Since the age of nine or ten, Katie Burns has had debilitating pain from endometriosis, a condition where tissue resembling the uterine lining grows outside the uterus. For years, Katie was in the dar...
www.npr.org
September 27, 2025 at 9:30 AM
Interesting episode of short wave about the origin of endometriosis. I really appreciate that they end with how uncertainty in NIH funding affects the future of their work.
www.npr.org/2025/09/26/n...
www.npr.org/2025/09/26/n...
Reposted by Elizabeth Rideout
2nd paper outta my PhD is NOW PUBLISHED😭
🧬🖥️ 🦑Here we show how comparative #genomics 🧬 is a powerful tool to detect putative #SexDetermination genes: Dmrt1L & SoxH from #bivalves 🦪 share evolutionary patterns with Sry from #mammals 🐗 but not with genes from
#drosophila 🪰
doi.org/10.1111/mec....
🧬🖥️ 🦑Here we show how comparative #genomics 🧬 is a powerful tool to detect putative #SexDetermination genes: Dmrt1L & SoxH from #bivalves 🦪 share evolutionary patterns with Sry from #mammals 🐗 but not with genes from
#drosophila 🪰
doi.org/10.1111/mec....
September 22, 2025 at 3:11 PM
2nd paper outta my PhD is NOW PUBLISHED😭
🧬🖥️ 🦑Here we show how comparative #genomics 🧬 is a powerful tool to detect putative #SexDetermination genes: Dmrt1L & SoxH from #bivalves 🦪 share evolutionary patterns with Sry from #mammals 🐗 but not with genes from
#drosophila 🪰
doi.org/10.1111/mec....
🧬🖥️ 🦑Here we show how comparative #genomics 🧬 is a powerful tool to detect putative #SexDetermination genes: Dmrt1L & SoxH from #bivalves 🦪 share evolutionary patterns with Sry from #mammals 🐗 but not with genes from
#drosophila 🪰
doi.org/10.1111/mec....
Taking in my favorite part of Vancouver airport on the way to EDRC in Alicante - excited to see folks there for all things Drosophila!
September 23, 2025 at 11:45 PM
Taking in my favorite part of Vancouver airport on the way to EDRC in Alicante - excited to see folks there for all things Drosophila!
Reposted by Elizabeth Rideout
Studies of prohormone convertase knockouts in mouse islets reveal plasticity in proglucagon processing to support intra-islet α cell-to-β cell communication, normally dominated by glucagon secretion www.science.org/doi/10.1126/...
α cells use both PC1/3 and PC2 to process proglucagon peptides and control insulin secretion
α cells can generate and secrete both glucagon and GLP-1 with distinct processing enzymes to control metabolism.
www.science.org
September 20, 2025 at 11:44 AM
Studies of prohormone convertase knockouts in mouse islets reveal plasticity in proglucagon processing to support intra-islet α cell-to-β cell communication, normally dominated by glucagon secretion www.science.org/doi/10.1126/...
Very proud of Celena Cherian in the lab, who contributed data to www.biorxiv.org/content/10.1... Briefly, Celena showed female fat body cells have higher ribosomal protein expression and more protein synthesis than males. This difference persists even after cell size is accounted for!
Cell type specific allometry controls sex-differences in Drosophila body size
Species and sex-specific differences in organ size are fundamental features of animal biology, yet the mechanisms that drive these differences remain debated. Adult female Drosophila are larger than m...
www.biorxiv.org
September 20, 2025 at 2:24 PM
Very proud of Celena Cherian in the lab, who contributed data to www.biorxiv.org/content/10.1... Briefly, Celena showed female fat body cells have higher ribosomal protein expression and more protein synthesis than males. This difference persists even after cell size is accounted for!
The next paper from @pujabiswas.bsky.social PhD has been posted! www.biorxiv.org/content/10.1... Puja found a sex difference in levels of hormones produced by gut enteroendocrine cells.
Sex-biased expression of enteroendocrine cell-derived hormones contributes to higher fat storage in Drosophila females
Enteroendocrine (EE) cells in the Drosophila gut produce and release multiple factors, including Allatostatin A (AstA), Allatostatin C (AstC), neuropeptide F (NPF), tachykinin (Tk), Diuretic hormone 3...
www.biorxiv.org
September 20, 2025 at 2:07 PM
The next paper from @pujabiswas.bsky.social PhD has been posted! www.biorxiv.org/content/10.1... Puja found a sex difference in levels of hormones produced by gut enteroendocrine cells.
I have gotten a bit behind at sharing the lab’s latest work - this paper is now published - check it out! www.cell.com/cell-reports... Long story short: insulin is the major determinant of female fat storage, with a relatively minor effect on males.
September 20, 2025 at 1:39 PM
I have gotten a bit behind at sharing the lab’s latest work - this paper is now published - check it out! www.cell.com/cell-reports... Long story short: insulin is the major determinant of female fat storage, with a relatively minor effect on males.
Reposted by Elizabeth Rideout
In our Forest of Biologists we fund the restoration and preservation of ancient woodland and dedicate these trees to our peer reviewers.
There are now over 10,000 trees for peer reviews!
Thank you to all our peer reviewers. Find out more:
forest.biologists.com
#PRW2025 @peerreviewweek.bsky.social
There are now over 10,000 trees for peer reviews!
Thank you to all our peer reviewers. Find out more:
forest.biologists.com
#PRW2025 @peerreviewweek.bsky.social
September 19, 2025 at 10:58 AM
In our Forest of Biologists we fund the restoration and preservation of ancient woodland and dedicate these trees to our peer reviewers.
There are now over 10,000 trees for peer reviews!
Thank you to all our peer reviewers. Find out more:
forest.biologists.com
#PRW2025 @peerreviewweek.bsky.social
There are now over 10,000 trees for peer reviews!
Thank you to all our peer reviewers. Find out more:
forest.biologists.com
#PRW2025 @peerreviewweek.bsky.social
Reposted by Elizabeth Rideout
Congratulations to my PhD student, Ujjayita for being awarded the DBT-CTEP international travel support grant to attend @edrc2025.bsky.social in Alicante, Spain. Ujjayita will be giving a talk at EDRC. Looking forward to EDRC 2025 :) Spain here we come!!
#Drosophila #EDRC2025
#Drosophila #EDRC2025
September 17, 2025 at 4:23 AM
Congratulations to my PhD student, Ujjayita for being awarded the DBT-CTEP international travel support grant to attend @edrc2025.bsky.social in Alicante, Spain. Ujjayita will be giving a talk at EDRC. Looking forward to EDRC 2025 :) Spain here we come!!
#Drosophila #EDRC2025
#Drosophila #EDRC2025
Reposted by Elizabeth Rideout
Very proud of former Kumar lab PhD student, Alison Ordway, for receiving a K99 award from the National Eye Institute on her work describing photoreceptor patterning in Drosophila and mosquito compound eyes. Keep your eyes out for Alison when she goes out on the job market.
September 16, 2025 at 3:58 PM
Very proud of former Kumar lab PhD student, Alison Ordway, for receiving a K99 award from the National Eye Institute on her work describing photoreceptor patterning in Drosophila and mosquito compound eyes. Keep your eyes out for Alison when she goes out on the job market.
Reposted by Elizabeth Rideout
Geronazzo, J., Heimerl, A., Lindell, L., McCrimmon, S., Stormer, C., Horvai, B., Johnson, I. P., Peterson, T. M., Zuckerman, J., Scott, A. I., Course, M. M. (2025). Characterizing fatty acid oxidation genes in #Drosophila. G3 (Bethesda), academic.oup.com/g3journal/ar...
Characterizing fatty acid oxidation genes in Drosophila
Abstract. In this study, we leverage the power and tractability of Drosophila genetics to better understand the molecular mechanisms underlying a group of
academic.oup.com
September 12, 2025 at 12:41 AM
Geronazzo, J., Heimerl, A., Lindell, L., McCrimmon, S., Stormer, C., Horvai, B., Johnson, I. P., Peterson, T. M., Zuckerman, J., Scott, A. I., Course, M. M. (2025). Characterizing fatty acid oxidation genes in #Drosophila. G3 (Bethesda), academic.oup.com/g3journal/ar...
Reposted by Elizabeth Rideout
Studies of pancreatic slices from organ donors reveals beta cell dysfunction in #T1D occurs independently of local autoimmunity www.cell.com/cell-reports...
Beta cell dysfunction occurs independently of insulitis in type 1 diabetes pathogenesis
Huber et al. used live pancreas slices from donors with recently diagnosed type 1
diabetes to reveal beta cell dysfunction independent of local immune cells. Real-time
imaging and molecular analyses u...
www.cell.com
August 28, 2025 at 3:32 PM
Studies of pancreatic slices from organ donors reveals beta cell dysfunction in #T1D occurs independently of local autoimmunity www.cell.com/cell-reports...
Reposted by Elizabeth Rideout
Dear GenZ members of the #Drosophila community! You are needed to make cool fly research viral in your social media world! As a boomer I do not understand that sphere, but I can consult and contribute our enormous fund of outreach resources: droso4public.wordpress.com. Please, get in contact!
(no title)
droso4public is a central resource store supporting science communication and advocacy for Drosophila
droso4public.wordpress.com
August 25, 2025 at 10:02 AM
Dear GenZ members of the #Drosophila community! You are needed to make cool fly research viral in your social media world! As a boomer I do not understand that sphere, but I can consult and contribute our enormous fund of outreach resources: droso4public.wordpress.com. Please, get in contact!
Reposted by Elizabeth Rideout
Are you an early-career researcher using Drosophila in your research?
Sign up to be matched with a mentor as part of FlyCROSS 2025-26.
Apply by 1 September 2025.
thenode.biologists.com/mentees-flyc...
#Drosophila #DevelopmentalBiology #Mentor #Career #Biology #FlyCross
Sign up to be matched with a mentor as part of FlyCROSS 2025-26.
Apply by 1 September 2025.
thenode.biologists.com/mentees-flyc...
#Drosophila #DevelopmentalBiology #Mentor #Career #Biology #FlyCross
FlyCROSS 2025–26: Call for Drosophila early career scientists - the Node
Do not miss this call for mentees from the Drosophila community. Scan the QR Code & fill the mentee survey ! The Fly Board is excited to announce the
thenode.biologists.com
August 26, 2025 at 9:23 AM
Are you an early-career researcher using Drosophila in your research?
Sign up to be matched with a mentor as part of FlyCROSS 2025-26.
Apply by 1 September 2025.
thenode.biologists.com/mentees-flyc...
#Drosophila #DevelopmentalBiology #Mentor #Career #Biology #FlyCross
Sign up to be matched with a mentor as part of FlyCROSS 2025-26.
Apply by 1 September 2025.
thenode.biologists.com/mentees-flyc...
#Drosophila #DevelopmentalBiology #Mentor #Career #Biology #FlyCross
In case folks missed this post the first time - join us in Vancouver at The University of British Columbia. Two faculty positions are available (see links in original post), and views like this will be close at hand:
August 26, 2025 at 2:56 PM
In case folks missed this post the first time - join us in Vancouver at The University of British Columbia. Two faculty positions are available (see links in original post), and views like this will be close at hand: