Perinatal mood and anxiety disorders affect one in five women during pregnancy and up to one year postpartum and are a strong predictor of perinatal suicidality. In this Review, Singla et al. provide an overview of evidence-based psychotherapies for perinatal depression, anxiety, post-traumatic stress and suicidality and describe their underlying mechanisms.

Authors analyse paired viral and bacterial shotgun metagenomics data from individual honeybee guts, revealing modular, nested phage–bacteria networks, with viral diversity mirroring bacterial strain c...

Reactive oxygen species function as key signals in plant adaptation to environmental stresses like drought. Roots respond to transient water unavailability by temporarily ceasing branching through the...

Author summary Parasites of the genus Leishmania cause a series of neglected tropical diseases collectively known as leishmaniasis. Many isolates of these parasites possess Leishmania RNA viruses (LRV...

West Anatolia has been a crucial yet elusive element in the Neolithic expansion from the Fertile Crescent to Europe. In this work, we describe the changing genetic and cultural landscapes of early Hol...

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Nature Reviews Genetics, Published online: 06 June 2025; doi:10.1038/s41576-025-00854-xArthropod-borne viruses have a substantial impact on global health, with climate change and urbanization exacerbating their emergence. Integrating genomic surveillance and phylogenetic models with ecological and epidemiological data enhances our understanding of virus transmission dynamics, aiding in effective detection and the response to disease outbreaks affecting humans and animals.

Single-cell and spatial transcriptomics analysis of stricturing Crohn’s disease highlights cellular heterogeneity in fibrotic tissue and identifies neighborhoods of fibroblasts and immune cells contri...

This review discusses the cellular pathways mediating Targeted Protein Degradation approaches and points to some gaps in our understanding of the biology of novel therapeutic tools such as PROTACs.

Today’s uniquely challenging biotech climate may result in a more resilient sector.

Nature Reviews Molecular Cell Biology, Published online: 10 June 2025; doi:10.1038/s41580-025-00868-7A machine learning model was trained to quantify how closely neurons differentiated in a dish from stem cells resemble those found in the brain.

Broad and potent neutralizing antibodies to SARS-CoV-2 variants can be efficiently identified via accurate deep-mutational-scanning-based prediction of viral evolution and delivered to mice using mRNA...

Investigations in wild bats and non-human primates in Brazil and Costa Rica reveal diverse morbillivirus ecology in neotropical bats and evidence for host jumps.

The Pandemic Agreement proves that nations can work together to tackle future pandemic threats and provides cautious optimism in otherwise uncertain times.

Magnetoencephalography in human participants paired with Rapid Invisible Frequency Tagging reveals that excitability in early visual cortex is modulated to boost targets and suppress distractors in gu...