Yu Ieda 家田有
@yuieda1.bsky.social
Postdoc in Institut Pasteur (PPU) @Jérôme Gros’ lab Developmental Biology & Morphogenesis
Reposted by Yu Ieda 家田有
Our research scientist Núria Ros-Rocher won the 1st prize @zeiss-microscopy.bsky.social microscopy contest with this beautiful choano colony www.zeiss.fr/microscopie/... 🥳
C. flexa might not yet be a genetic model, but it is now at least a calendar model, which counts for something. I think.
C. flexa might not yet be a genetic model, but it is now at least a calendar model, which counts for something. I think.
January 12, 2026 at 7:28 PM
Our research scientist Núria Ros-Rocher won the 1st prize @zeiss-microscopy.bsky.social microscopy contest with this beautiful choano colony www.zeiss.fr/microscopie/... 🥳
C. flexa might not yet be a genetic model, but it is now at least a calendar model, which counts for something. I think.
C. flexa might not yet be a genetic model, but it is now at least a calendar model, which counts for something. I think.
Reposted by Yu Ieda 家田有
Why does life explore so few of the forms it could possibly take? Using fractal descriptors, this #scienceadvances paper shows that Earth’s biosphere clusters around simple shapes, reflecting deep evolutionary constraints. @artemyte.bsky.social @manlius.bsky.social www.science.org/doi/pdf/10.1...
January 11, 2026 at 1:23 PM
Why does life explore so few of the forms it could possibly take? Using fractal descriptors, this #scienceadvances paper shows that Earth’s biosphere clusters around simple shapes, reflecting deep evolutionary constraints. @artemyte.bsky.social @manlius.bsky.social www.science.org/doi/pdf/10.1...
Reposted by Yu Ieda 家田有
Nature research paper: Genetic switch between unicellularity and multicellularity in marine yeasts
go.nature.com/4poZ9HP
go.nature.com/4poZ9HP
Genetic switch between unicellularity and multicellularity in marine yeasts - Nature
Myb1 functions as a switch-like regulator of state transitions in Hortaea werneckii, whereby its expression and degradation are coupled to nutrient conditions, stabilizing unicellular or multicellular growth.
go.nature.com
January 8, 2026 at 11:47 AM
Nature research paper: Genetic switch between unicellularity and multicellularity in marine yeasts
go.nature.com/4poZ9HP
go.nature.com/4poZ9HP
I’m pleased to share our latest preprint (my first as 1st-author) from Jérôme Gros’ group (@jeromegros.bsky.social), now on bioRxiv. It reports actin and myosin dynamics during epithelial remodeling in avian gastrulation. (doi: doi.org/10.64898/202...)
Actin and myosin dynamics during epithelial remodeling in avian gastrulation
Epithelial remodeling is powered by contractile forces exerted by the actomyosin cytoskeleton. In invertebrates, pulsatile contractile flows of the medio-apical actomyosin cortex have been shown to be...
doi.org
December 19, 2025 at 4:33 PM
I’m pleased to share our latest preprint (my first as 1st-author) from Jérôme Gros’ group (@jeromegros.bsky.social), now on bioRxiv. It reports actin and myosin dynamics during epithelial remodeling in avian gastrulation. (doi: doi.org/10.64898/202...)
Reposted by Yu Ieda 家田有
To build the body plan of an animal, cells must adhere to one another via cell-cell junctions. We now know these assemble as punctate protein complexes containing thousands of proteins, but how this occurs remains mysterious. 1/n 🧪
www.molbiolcell.org/doi/full/10....
www.molbiolcell.org/doi/full/10....
December 14, 2025 at 2:59 PM
To build the body plan of an animal, cells must adhere to one another via cell-cell junctions. We now know these assemble as punctate protein complexes containing thousands of proteins, but how this occurs remains mysterious. 1/n 🧪
www.molbiolcell.org/doi/full/10....
www.molbiolcell.org/doi/full/10....
Reposted by Yu Ieda 家田有
Join us next week for the second Eastern VGZT of the season! 🤩
🗓️ Wednesday, December 10th
⏰ 9:00 UTC / 9:00 GMT / 10:00 CET / 14:30 IST / 18:00 JST / 20:00 AEDT
Our speakers are:
👉 Guojun Sheng
👉 Jennifer Zenker
See you there! ✨
🗓️ Wednesday, December 10th
⏰ 9:00 UTC / 9:00 GMT / 10:00 CET / 14:30 IST / 18:00 JST / 20:00 AEDT
Our speakers are:
👉 Guojun Sheng
👉 Jennifer Zenker
See you there! ✨
December 6, 2025 at 7:45 PM
Join us next week for the second Eastern VGZT of the season! 🤩
🗓️ Wednesday, December 10th
⏰ 9:00 UTC / 9:00 GMT / 10:00 CET / 14:30 IST / 18:00 JST / 20:00 AEDT
Our speakers are:
👉 Guojun Sheng
👉 Jennifer Zenker
See you there! ✨
🗓️ Wednesday, December 10th
⏰ 9:00 UTC / 9:00 GMT / 10:00 CET / 14:30 IST / 18:00 JST / 20:00 AEDT
Our speakers are:
👉 Guojun Sheng
👉 Jennifer Zenker
See you there! ✨
Reposted by Yu Ieda 家田有
Register now for the EMBO Workshop "Limb development and regeneration: Quantitative, ecological, and diversification studies" in #Tokyo, Japan, 23–27 March 2026.
Abstract submission/Registration deadline:
12/15 December 2025
https://meetings.embo.org/event/26-limb-dev
#EMBOLimbDev #EMBOevents 🧪
Abstract submission/Registration deadline:
12/15 December 2025
https://meetings.embo.org/event/26-limb-dev
#EMBOLimbDev #EMBOevents 🧪
November 25, 2025 at 4:10 PM
Register now for the EMBO Workshop "Limb development and regeneration: Quantitative, ecological, and diversification studies" in #Tokyo, Japan, 23–27 March 2026.
Abstract submission/Registration deadline:
12/15 December 2025
https://meetings.embo.org/event/26-limb-dev
#EMBOLimbDev #EMBOevents 🧪
Abstract submission/Registration deadline:
12/15 December 2025
https://meetings.embo.org/event/26-limb-dev
#EMBOLimbDev #EMBOevents 🧪
Reposted by Yu Ieda 家田有
Interested in polarity and mechanics during epithelial morphogenesis? Considering joining us! Students to be hired initially as Research Associates. Postdocs encouraged to obtain fellowship, and we help/train you to do that. Apply to tinyurl.com/y6x489t5. Deadline Dec 15.
Please repost!
Please repost!
November 3, 2025 at 1:53 AM
Interested in polarity and mechanics during epithelial morphogenesis? Considering joining us! Students to be hired initially as Research Associates. Postdocs encouraged to obtain fellowship, and we help/train you to do that. Apply to tinyurl.com/y6x489t5. Deadline Dec 15.
Please repost!
Please repost!
Reposted by Yu Ieda 家田有
Want to know why #microtubules should be depolymerised before #cyokinesis is completed.
#mitosis #cellbiology #midbody
Check out our new study in @jcellsci.bsky.social @bric-cdfd.bsky.social
doi.org/10.1242/jcs....
#mitosis #cellbiology #midbody
Check out our new study in @jcellsci.bsky.social @bric-cdfd.bsky.social
doi.org/10.1242/jcs....
October 18, 2025 at 9:53 AM
Want to know why #microtubules should be depolymerised before #cyokinesis is completed.
#mitosis #cellbiology #midbody
Check out our new study in @jcellsci.bsky.social @bric-cdfd.bsky.social
doi.org/10.1242/jcs....
#mitosis #cellbiology #midbody
Check out our new study in @jcellsci.bsky.social @bric-cdfd.bsky.social
doi.org/10.1242/jcs....
Reposted by Yu Ieda 家田有
Amazing day at #GastrulationReloaded with thought provoking science and jaw dropping methods.
Also, for no reason at all, re-posting this open Collection: www.nature.com/collections/...
Don’t sweat the deadline, we’ll extend it and I’ll add relevant papers that come to me @natcomms.nature.com
Also, for no reason at all, re-posting this open Collection: www.nature.com/collections/...
Don’t sweat the deadline, we’ll extend it and I’ll add relevant papers that come to me @natcomms.nature.com
Organizers and self-organization in developmental biology
This collection highlights papers studying self-organization, symmetry breaking, and developmental organizers.
www.nature.com
October 15, 2025 at 7:25 PM
Amazing day at #GastrulationReloaded with thought provoking science and jaw dropping methods.
Also, for no reason at all, re-posting this open Collection: www.nature.com/collections/...
Don’t sweat the deadline, we’ll extend it and I’ll add relevant papers that come to me @natcomms.nature.com
Also, for no reason at all, re-posting this open Collection: www.nature.com/collections/...
Don’t sweat the deadline, we’ll extend it and I’ll add relevant papers that come to me @natcomms.nature.com
Reposted by Yu Ieda 家田有
Happy to share the last version of our story @currentbiology.bsky.social on the role of interfacial tension in mechanical cell competition led by @leovalon.bsky.social and Alexis Matamoro Vidal
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
October 9, 2025 at 3:27 PM
Happy to share the last version of our story @currentbiology.bsky.social on the role of interfacial tension in mechanical cell competition led by @leovalon.bsky.social and Alexis Matamoro Vidal
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Reposted by Yu Ieda 家田有
New publication | Science Advances www.science.org/doi/10.1126/...
Plasticity of ventricle position after heart looping in heterotaxy with right isomerism
The left/right position of ventricles needs to be maintained after heart looping, an unexpected step affected in heterotaxy.
www.science.org
September 24, 2025 at 5:27 PM
New publication | Science Advances www.science.org/doi/10.1126/...
Reposted by Yu Ieda 家田有
Fantastic work from Xi and Qi-long! Chicken ES cells will take classic chicken embryology to a new level.
A method to produce embryonic stem cells for a range of bird species opens up opportunities in agriculture, developmental biology and species conservation #NBTNV go.nature.com/4ntGnih
rdcu.be/eJagy
rdcu.be/eJagy
Embryonic stem cells across bird species - Nature Biotechnology
A method to produce embryonic stem cells for a range of bird species opens up opportunities in agriculture, developmental biology and species conservation.
go.nature.com
October 10, 2025 at 6:15 AM
Fantastic work from Xi and Qi-long! Chicken ES cells will take classic chicken embryology to a new level.
Reposted by Yu Ieda 家田有
During #development, distal visceral #endoderm (DVE) cells migrate to shape A-P axis specification. @m-stower.bsky.social @srinivas-lab.bsky.social &co reveal the role of Ca2+ dynamics in this, showing that inhibition of #calcium transients causes DVE arrest @plosbiology.org 🧪 plos.io/4nHWxF4
October 7, 2025 at 10:26 AM
Reposted by Yu Ieda 家田有
Latest from ours: www.cell.com/cell-reports...
This is two stories in one: a case study/cautionary tale on developing genetic tools in new organisms, and the first hint at a gene regulatory network for choanoflagellate multicellular development (which turn out to involve a Hippo/YAP/ECM loop!) A 🧵
This is two stories in one: a case study/cautionary tale on developing genetic tools in new organisms, and the first hint at a gene regulatory network for choanoflagellate multicellular development (which turn out to involve a Hippo/YAP/ECM loop!) A 🧵
October 5, 2025 at 10:35 AM
Latest from ours: www.cell.com/cell-reports...
This is two stories in one: a case study/cautionary tale on developing genetic tools in new organisms, and the first hint at a gene regulatory network for choanoflagellate multicellular development (which turn out to involve a Hippo/YAP/ECM loop!) A 🧵
This is two stories in one: a case study/cautionary tale on developing genetic tools in new organisms, and the first hint at a gene regulatory network for choanoflagellate multicellular development (which turn out to involve a Hippo/YAP/ECM loop!) A 🧵
Reposted by Yu Ieda 家田有
⏳ Still time to register + submit your poster abstract
🗓️ Deadline: Sept 19!
🗓️ Deadline: Sept 19!
Registration is now open!
Gastrulation Reloaded: Developing, engineering & evolving the body plan
📅 October 14–17, 2025
📍 Paris, France
🗓️ Abstract & early bird deadline: July 15, 2025
www.gastrulation-reloaded.conferences-pasteur.org/home
Exceptional lineup of speakers & many selected talks
Gastrulation Reloaded: Developing, engineering & evolving the body plan
📅 October 14–17, 2025
📍 Paris, France
🗓️ Abstract & early bird deadline: July 15, 2025
www.gastrulation-reloaded.conferences-pasteur.org/home
Exceptional lineup of speakers & many selected talks
September 5, 2025 at 2:48 PM
⏳ Still time to register + submit your poster abstract
🗓️ Deadline: Sept 19!
🗓️ Deadline: Sept 19!
Reposted by Yu Ieda 家田有
🎓 Applications for Institut Pasteur's PhD programs open Sept 1-Oct 20, 2025 for October 2026 entry.
Apply to up to 4 projects across 6 programs: PPU, PPU-IMAGINE @institutimagine.bsky.social, PPU-@ox.ac.uk, PPU-EID @upcite.bsky.social & more 🧬
Register now ✍️ www.pasteur.fr/en/education...
Apply to up to 4 projects across 6 programs: PPU, PPU-IMAGINE @institutimagine.bsky.social, PPU-@ox.ac.uk, PPU-EID @upcite.bsky.social & more 🧬
Register now ✍️ www.pasteur.fr/en/education...
September 1, 2025 at 9:44 AM
🎓 Applications for Institut Pasteur's PhD programs open Sept 1-Oct 20, 2025 for October 2026 entry.
Apply to up to 4 projects across 6 programs: PPU, PPU-IMAGINE @institutimagine.bsky.social, PPU-@ox.ac.uk, PPU-EID @upcite.bsky.social & more 🧬
Register now ✍️ www.pasteur.fr/en/education...
Apply to up to 4 projects across 6 programs: PPU, PPU-IMAGINE @institutimagine.bsky.social, PPU-@ox.ac.uk, PPU-EID @upcite.bsky.social & more 🧬
Register now ✍️ www.pasteur.fr/en/education...
Reposted by Yu Ieda 家田有
🚨 theory/math devbio preprint alert!!! 🚨
Led by my v. talented PhD student, Daniel Muzatko, we’ve found some rather general and intriguing constraints on reaction-diffusion systems that allow them to self-organize developmental patterns:
www.biorxiv.org/content/10.1...
Led by my v. talented PhD student, Daniel Muzatko, we’ve found some rather general and intriguing constraints on reaction-diffusion systems that allow them to self-organize developmental patterns:
www.biorxiv.org/content/10.1...
June 2, 2025 at 1:03 PM
🚨 theory/math devbio preprint alert!!! 🚨
Led by my v. talented PhD student, Daniel Muzatko, we’ve found some rather general and intriguing constraints on reaction-diffusion systems that allow them to self-organize developmental patterns:
www.biorxiv.org/content/10.1...
Led by my v. talented PhD student, Daniel Muzatko, we’ve found some rather general and intriguing constraints on reaction-diffusion systems that allow them to self-organize developmental patterns:
www.biorxiv.org/content/10.1...
Reposted by Yu Ieda 家田有
🔈 We’re excited to welcome Jérôme Gros @jeromegros.bsky.social as an invited speaker at #ICDB2025!
Jérôme's stunning in vivo imaging reveals the cellular mechanics driving vertebrate morphogenesis. 🎥🐣🧪
Jérôme's stunning in vivo imaging reveals the cellular mechanics driving vertebrate morphogenesis. 🎥🐣🧪
May 20, 2025 at 1:35 PM
🔈 We’re excited to welcome Jérôme Gros @jeromegros.bsky.social as an invited speaker at #ICDB2025!
Jérôme's stunning in vivo imaging reveals the cellular mechanics driving vertebrate morphogenesis. 🎥🐣🧪
Jérôme's stunning in vivo imaging reveals the cellular mechanics driving vertebrate morphogenesis. 🎥🐣🧪
Reposted by Yu Ieda 家田有
🚨New preprint
Glad to share my postdoc work on the role of the hypoblast in primitive streak induction! Discover how live imaging observations led us to revisit the molecular mechanisms governing embryonic axis induction
Thanks to @jeromegros.bsky.social and all co-authors!
doi.org/10.1101/2025...
Glad to share my postdoc work on the role of the hypoblast in primitive streak induction! Discover how live imaging observations led us to revisit the molecular mechanisms governing embryonic axis induction
Thanks to @jeromegros.bsky.social and all co-authors!
doi.org/10.1101/2025...
Live imaging and functional characterization of the avian hypoblast redefine the mechanisms of primitive streak induction
In birds and mammals, the formation of the primitive streak, the hallmark of the primary axis and site of gastrulation, is thought to occur when an anterior displacement of the hypoblast (visceral end...
doi.org
May 19, 2025 at 8:59 AM
🚨New preprint
Glad to share my postdoc work on the role of the hypoblast in primitive streak induction! Discover how live imaging observations led us to revisit the molecular mechanisms governing embryonic axis induction
Thanks to @jeromegros.bsky.social and all co-authors!
doi.org/10.1101/2025...
Glad to share my postdoc work on the role of the hypoblast in primitive streak induction! Discover how live imaging observations led us to revisit the molecular mechanisms governing embryonic axis induction
Thanks to @jeromegros.bsky.social and all co-authors!
doi.org/10.1101/2025...
Reposted by Yu Ieda 家田有
📢 Fresh off the press and featuring new exciting experiments! 🧪
We show how glycolytic activity instructs germ layer proportions through regulation of Nodal and Wnt signaling - happy to finally share this 😊
doi.org/10.1016/j.st...
B2B with @jesseveenvliet.bsky.social lab: doi.org/10.1016/j.st... 🤩
We show how glycolytic activity instructs germ layer proportions through regulation of Nodal and Wnt signaling - happy to finally share this 😊
doi.org/10.1016/j.st...
B2B with @jesseveenvliet.bsky.social lab: doi.org/10.1016/j.st... 🤩
April 16, 2025 at 5:40 PM
📢 Fresh off the press and featuring new exciting experiments! 🧪
We show how glycolytic activity instructs germ layer proportions through regulation of Nodal and Wnt signaling - happy to finally share this 😊
doi.org/10.1016/j.st...
B2B with @jesseveenvliet.bsky.social lab: doi.org/10.1016/j.st... 🤩
We show how glycolytic activity instructs germ layer proportions through regulation of Nodal and Wnt signaling - happy to finally share this 😊
doi.org/10.1016/j.st...
B2B with @jesseveenvliet.bsky.social lab: doi.org/10.1016/j.st... 🤩
Reposted by Yu Ieda 家田有
Pu Zhang @puzhang.bsky.social, Taylor Medwig-Kinney @tmedwigkinney.bsky.social, & colleagues from the Goldstein lab found that a population of Arp2/3 recruited to where cells touch each other makes an unexpected contribution to apical constriction rupress.org/jcb/article/...
March 5, 2025 at 6:50 PM
Pu Zhang @puzhang.bsky.social, Taylor Medwig-Kinney @tmedwigkinney.bsky.social, & colleagues from the Goldstein lab found that a population of Arp2/3 recruited to where cells touch each other makes an unexpected contribution to apical constriction rupress.org/jcb/article/...
Reposted by Yu Ieda 家田有
Out now @naturecomms.bsky.social with extra analyses & data: how distinct gene regulatory dynamics specify vertebrate skeletal cells from three embryonic lineages, how this makes them 'distinct cell types' and what it implies for their evolutionary trajectories > rdcu.be/ecbM2
👏👏 to all co-authors!
👏👏 to all co-authors!
Distinct gene regulatory dynamics drive skeletogenic cell fate convergence during vertebrate embryogenesis
Nature Communications - Vertebrate skeletogenic cells of different embryonic origins are distinct cell types, based on their lineage-specific gene regulatory logic that specifies them, and the...
rdcu.be
March 5, 2025 at 8:33 AM
Out now @naturecomms.bsky.social with extra analyses & data: how distinct gene regulatory dynamics specify vertebrate skeletal cells from three embryonic lineages, how this makes them 'distinct cell types' and what it implies for their evolutionary trajectories > rdcu.be/ecbM2
👏👏 to all co-authors!
👏👏 to all co-authors!
Reposted by Yu Ieda 家田有
ICYMI: Discover new insights on chromosome size sensing by kinetochores, mechanical resistance at tight junctions, force-exerting focal adhesions formed by T cells, and how nuclei serve as mechanical bumpers, in our new #Mechanobiology collection 👉 https://buff.ly/3EK0uaq
February 26, 2025 at 8:12 PM
ICYMI: Discover new insights on chromosome size sensing by kinetochores, mechanical resistance at tight junctions, force-exerting focal adhesions formed by T cells, and how nuclei serve as mechanical bumpers, in our new #Mechanobiology collection 👉 https://buff.ly/3EK0uaq
Reposted by Yu Ieda 家田有
Check out our latest paper in Science Advances, in which we built a constriction-based microfluidic device to measure the deformability of oocytes to assess their mechanical properties with minimal impact.
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Noninvasive characterization of oocyte deformability in microconstrictions
A microfluidic measurement method translates oocyte mechanical characterization into oocyte quality assessment.
www.science.org
February 20, 2025 at 7:11 AM
Check out our latest paper in Science Advances, in which we built a constriction-based microfluidic device to measure the deformability of oocytes to assess their mechanical properties with minimal impact.
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...