Kongju Zhu
kongjuzhu.bsky.social
Kongju Zhu
@kongjuzhu.bsky.social
Postdoc @harvardmed.bsky.social. Interested in time-space coordination during development. #DevBio #StemCell #InHoxWeTrust. Like #Simplicity
Reposted by Kongju Zhu
A lovely example of the interplay of morphogen dynamics, tissue mechanics, cell mechanics and signal transduction at the most crucial stage of embryogenesis. And a good example of why talk of development being "programmed" into the genome is simply the wrong language.
www.cell.com/cell-stem-ce...
Crosstalk between tissue mechanics and BMP4 signaling regulates symmetry breaking in human gastrula models
Brivanlou and colleagues used optogenetics to spatially control BMP4 expression in human stem cell models across different mechanical regimes. By combining these experiments with mathematical modeling...
www.cell.com
November 6, 2025 at 8:56 PM
Reposted by Kongju Zhu
🚨Excited to kick off our online seminar series on Metabolism in Development and Physiology!

Please help us grow a collaborative and supportive community by joining (<1min): forms.gle/Y8QzucogKKrZ...
#Metabolism #Development #StemCells

Please RT! 🙏
October 28, 2025 at 4:39 PM
Fantastic work from Xi and Qi-long! Chicken ES cells will take classic chicken embryology to a new level.
October 10, 2025 at 6:15 AM
A true role model in science. Rest in peace.
A Nobel-winning scientist of great modesty and humour, John Gurdon died on 7 Oct. Not only did he make a discovery that laid the foundations for stem cell research, he also created one of the best environments for research at the Wellcome/CRUK Gurdon Institute wellcome.org/news/sir-joh...
Sir John Gurdon, 1933-2025 | Wellcome
A Nobel-winning scientist of great modesty and humour, John Gurdon died on 7 October. He made a discovery that opened up the field of cloning research, and created one of the best environments for res...
wellcome.org
October 9, 2025 at 11:13 PM
Reposted by Kongju Zhu
🚨📣 New preprint alert!
Excited to share my new postdoc work on direct force and mechanical properties measurements in live embryos!
A great team effort with A. Chamolly (theory), under the supervision of F. Corson and @jeromegros.bsky.social
📄 www.biorxiv.org/content/10.1...
#devbio #mechanics
Direct measurements of active forces and material properties unveil the active mechanics of early embryogenesis
Despite progress in probing tissue mechanics, direct long-term measurements in live embryonic epithelia are lacking. This limits our understanding of amniote embryonic morphogenesis, which takes place...
www.biorxiv.org
May 12, 2025 at 2:01 PM