Sigolène Meilhac
@meilhacsigolene.bsky.social
Heart Morphogenesis laboratory
Developmental biology, Congenital heart defects, Left-right asymmetry, Heterotaxy
@Institut Pasteur, Institut Imagine, Inserm, UPC - Paris
Developmental biology, Congenital heart defects, Left-right asymmetry, Heterotaxy
@Institut Pasteur, Institut Imagine, Inserm, UPC - Paris
New publication :
Despite being a core member of the PCP pathway, Vangl2 can play roles unrelated to planar polarity. This is the case during mouse heart morphogenesis.
Despite being a core member of the PCP pathway, Vangl2 can play roles unrelated to planar polarity. This is the case during mouse heart morphogenesis.
VANGL2 shapes the mouse heart tube from adjacent epithelia and without planar polarity https://www.biorxiv.org/content/10.1101/2025.09.05.674213v1
September 26, 2025 at 7:22 PM
New publication :
Despite being a core member of the PCP pathway, Vangl2 can play roles unrelated to planar polarity. This is the case during mouse heart morphogenesis.
Despite being a core member of the PCP pathway, Vangl2 can play roles unrelated to planar polarity. This is the case during mouse heart morphogenesis.
Congratulations Dr Amaia Ochandorena-Saa for a beautiful PhD, defended in front of Hiroshi Hamada, @bakkerslab.bsky.social, Alice Meunier and Jeanne Amiel
September 25, 2025 at 6:03 AM
Congratulations Dr Amaia Ochandorena-Saa for a beautiful PhD, defended in front of Hiroshi Hamada, @bakkerslab.bsky.social, Alice Meunier and Jeanne Amiel
New publication | Science Advances www.science.org/doi/10.1126/...
Plasticity of ventricle position after heart looping in heterotaxy with right isomerism
The left/right position of ventricles needs to be maintained after heart looping, an unexpected step affected in heterotaxy.
www.science.org
September 24, 2025 at 5:27 PM
New publication | Science Advances www.science.org/doi/10.1126/...
New article of the lab on Notch3, not only involved in vascular or neural defects, but also in heart defects and laterality defects.
Creating an asymmetric heart: @tbonnely.bsky.social @audreydsg.bsky.social @meilhacsigolene.bsky.social &co identify Notch3 as a novel asymmetric factor in lateral plate mesoderm that acts as a genetic modifier of NODAL to regulate #heart #morphogenesis @plosbiology.org 🧪 plos.io/42q6H4L
April 1, 2025 at 7:55 PM
New article of the lab on Notch3, not only involved in vascular or neural defects, but also in heart defects and laterality defects.
Reposted by Sigolène Meilhac
🧬 Join Institut Imagine as a Junior Group Leader!
- Junior Group Leader in Systems and Computational Biology
- Junior Group Leader in RNA Biology and Epigenomics
- Junior Group Leader in Artificial Intelligence for Genetics, Biology & Medicine
To submit your application : lnkd.in/enm-U2tH
- Junior Group Leader in Systems and Computational Biology
- Junior Group Leader in RNA Biology and Epigenomics
- Junior Group Leader in Artificial Intelligence for Genetics, Biology & Medicine
To submit your application : lnkd.in/enm-U2tH
January 24, 2025 at 1:09 PM
🧬 Join Institut Imagine as a Junior Group Leader!
- Junior Group Leader in Systems and Computational Biology
- Junior Group Leader in RNA Biology and Epigenomics
- Junior Group Leader in Artificial Intelligence for Genetics, Biology & Medicine
To submit your application : lnkd.in/enm-U2tH
- Junior Group Leader in Systems and Computational Biology
- Junior Group Leader in RNA Biology and Epigenomics
- Junior Group Leader in Artificial Intelligence for Genetics, Biology & Medicine
To submit your application : lnkd.in/enm-U2tH
Reposted by Sigolène Meilhac
The Weinstein Committee is soliciting nominations for the 2025 Markwald Award. If you have a scientist you'd like to nominate send it to mpatterson@mcw.edu by February 7th!
January 29, 2025 at 2:22 PM
The Weinstein Committee is soliciting nominations for the 2025 Markwald Award. If you have a scientist you'd like to nominate send it to mpatterson@mcw.edu by February 7th!
Reposted by Sigolène Meilhac
Join us for the 2025 Weinstein Cardiovascular Development and Regeneration Conference in Milwaukee, May 14-16! Registration and abstract submission are now open!!! Please share, retweet, and distribute! #WeinsteinCVD2025 REGISTER TODAY HERE childrenswi.org/weinstein
January 22, 2025 at 5:53 PM
Join us for the 2025 Weinstein Cardiovascular Development and Regeneration Conference in Milwaukee, May 14-16! Registration and abstract submission are now open!!! Please share, retweet, and distribute! #WeinsteinCVD2025 REGISTER TODAY HERE childrenswi.org/weinstein
Reposted by Sigolène Meilhac
We are opening a call for applications 2025 – Creation of new junior research groups at the Institut Pasteur in Paris @pasteur.fr all details on our web site : research.pasteur.fr/en/call/call...
Call for applications 2025 – Creation of new research groups at the Institut Pasteur | Research - Institut Pasteur
research.pasteur.fr
December 8, 2024 at 3:04 PM
We are opening a call for applications 2025 – Creation of new junior research groups at the Institut Pasteur in Paris @pasteur.fr all details on our web site : research.pasteur.fr/en/call/call...
Reposted by Sigolène Meilhac
Abstract submission is now open for the 2025 Weinstein Cardiovascular Development and Regeneration Conference at childrenswi.org/weinstein. The conference will be held in Milwaukee, May 14-16! Please share, retweet and distribute ❣️❣️❣️#WeinsteinCVD2025
January 16, 2025 at 6:00 PM
Abstract submission is now open for the 2025 Weinstein Cardiovascular Development and Regeneration Conference at childrenswi.org/weinstein. The conference will be held in Milwaukee, May 14-16! Please share, retweet and distribute ❣️❣️❣️#WeinsteinCVD2025
Reposted by Sigolène Meilhac
Yes! We are hiring! Looking for highly motivated people to make good use of our #ERC_SyG money 💶! The project is super cool, and the people are the best!! There are plenty of opportunities for international collaborations, too! Please help us spread the word!
Karina Yaniv Lab at the Weizmann Institute is seeking PhD students and postdoctoral researchers. Come work with us!
December 18, 2024 at 6:26 PM
Yes! We are hiring! Looking for highly motivated people to make good use of our #ERC_SyG money 💶! The project is super cool, and the people are the best!! There are plenty of opportunities for international collaborations, too! Please help us spread the word!
Reposted by Sigolène Meilhac
For the dev bio crowd : there is a call for junior group leader at Institut Pasteur in Paris and one of the axis covered is related to development. Come and join us in this exciting place and become one of our colleague @devstempasteur.bsky.social
Please RT !!
research.pasteur.fr/fr/call/call...
Please RT !!
research.pasteur.fr/fr/call/call...
Call for applications 2025 – Creation of new research groups at the Institut Pasteur | Research - Institut Pasteur
research.pasteur.fr
December 8, 2024 at 9:54 PM
For the dev bio crowd : there is a call for junior group leader at Institut Pasteur in Paris and one of the axis covered is related to development. Come and join us in this exciting place and become one of our colleague @devstempasteur.bsky.social
Please RT !!
research.pasteur.fr/fr/call/call...
Please RT !!
research.pasteur.fr/fr/call/call...
Reposted by Sigolène Meilhac
🚨🚨🚨 Not one, but 3 calls for junior group leaders opening at Imagine!!! [please share]
- Systems and computational biology
- RNA biology and epigenomics
- AI for genetics, biology and medicine
Come and join us!
www.nature.com/naturecareer...
- Systems and computational biology
- RNA biology and epigenomics
- AI for genetics, biology and medicine
Come and join us!
www.nature.com/naturecareer...
Jobs with Imagine Institute | Nature Careers
Search and apply for jobs with Imagine Institute on Nature Careers
www.nature.com
December 6, 2024 at 1:58 PM
🚨🚨🚨 Not one, but 3 calls for junior group leaders opening at Imagine!!! [please share]
- Systems and computational biology
- RNA biology and epigenomics
- AI for genetics, biology and medicine
Come and join us!
www.nature.com/naturecareer...
- Systems and computational biology
- RNA biology and epigenomics
- AI for genetics, biology and medicine
Come and join us!
www.nature.com/naturecareer...