Siegenthaler Lab
@siegenthalerlab.bsky.social
Neuroscience, meninges, blood-brain barrier, cake (or cookies)
http://siegenthalerlabcu.weebly.com/
http://siegenthalerlabcu.weebly.com/
Pinned
Hi Bluesky! I am Julie Siegenthaler, I am research faculty in Pediatrics at the University of Colorado, Anschutz Medical Campus in Aurora, Colorado USA - the @siegenthalerlab.bsky.social studies the meninges & brain vasculature & we ❤️ all CNS barriers...but the ones in the meninges are the best.
Reposted by Siegenthaler Lab
Considering next steps after MCB? SACNAS at Dartmouth is hosting an exciting Alumni Panel next week via Zoom, featuring MCB Alum(!).
When: Feb. 20, 12PM
Location: Kellogg 201
Lunch will be provided, so make sure to RSVP 🗓️
docs.google.com/forms/d/e/1F...
When: Feb. 20, 12PM
Location: Kellogg 201
Lunch will be provided, so make sure to RSVP 🗓️
docs.google.com/forms/d/e/1F...
February 10, 2026 at 2:34 PM
Considering next steps after MCB? SACNAS at Dartmouth is hosting an exciting Alumni Panel next week via Zoom, featuring MCB Alum(!).
When: Feb. 20, 12PM
Location: Kellogg 201
Lunch will be provided, so make sure to RSVP 🗓️
docs.google.com/forms/d/e/1F...
When: Feb. 20, 12PM
Location: Kellogg 201
Lunch will be provided, so make sure to RSVP 🗓️
docs.google.com/forms/d/e/1F...
Reposted by Siegenthaler Lab
Dear Blueskies, question: could you recommend a recent-ish, peer reviewed study on implicit/unconscious bias in faculty hiring? I know the classics, but I am wondering what new(ish) research is out there that could be used in a workshop setting. Thank you very much! #AcademicSky #EduSky 🗃️
February 10, 2026 at 11:33 PM
Dear Blueskies, question: could you recommend a recent-ish, peer reviewed study on implicit/unconscious bias in faculty hiring? I know the classics, but I am wondering what new(ish) research is out there that could be used in a workshop setting. Thank you very much! #AcademicSky #EduSky 🗃️
Reposted by Siegenthaler Lab
It is absolutely outrageous that Moderna’s flu vaccine was met with a “refusal-to-file” even after their approved their protocol with FDA and carried out the trial as agreed. This vaccine works better in older adults than the current flu vaccines.
apnews.com/article/mode...
apnews.com/article/mode...
Moderna says FDA refuses its application for new mRNA flu vaccine
The U.S. Food and Drug Administration is refusing to consider Moderna’s application for a new flu vaccine made with mRNA technology.
apnews.com
February 11, 2026 at 12:13 AM
It is absolutely outrageous that Moderna’s flu vaccine was met with a “refusal-to-file” even after their approved their protocol with FDA and carried out the trial as agreed. This vaccine works better in older adults than the current flu vaccines.
apnews.com/article/mode...
apnews.com/article/mode...
Reposted by Siegenthaler Lab
Glad to see this is out in @nber.org WP series and since my excellent co-author @chinemeluokafor.bsky.social and I have been discussing the results for the past few weeks, here's an old-fashioned paper thread on why protests matter/can work to influence economic redistribution 1/n
Study of the 2012 Occupy Nigeria protests presents evidence that protests increase fiscal transfers to protesting regions, but only in politically aligned areas, from @belindaarch.bsky.social, Chinemelu Okafor, Evans S. Osabuohien, and Tom Moerenhout www.nber.org/papers/w34787
February 10, 2026 at 7:36 PM
Glad to see this is out in @nber.org WP series and since my excellent co-author @chinemeluokafor.bsky.social and I have been discussing the results for the past few weeks, here's an old-fashioned paper thread on why protests matter/can work to influence economic redistribution 1/n
Reposted by Siegenthaler Lab
scdb2026.sites.ucsc.edu. Registration is open for the Santa Cruz Developmental Biology meeting AUGUST 2026. PLEASE SHARE.
Santa Cruz Developmental Biology Meeting
scdb2026.sites.ucsc.edu
February 10, 2026 at 8:13 PM
scdb2026.sites.ucsc.edu. Registration is open for the Santa Cruz Developmental Biology meeting AUGUST 2026. PLEASE SHARE.
Reposted by Siegenthaler Lab
The Trump administration is planning to terminate $600M of CDC grants to CA, CO, MN, and IL. We're publishing the full list.
They are using vulnerable communities as a weapon to dismantle public health, targeting partisan enemies, and manipulating media. 🧵 1/5
grant-witness.us/posts/2026-0...
They are using vulnerable communities as a weapon to dismantle public health, targeting partisan enemies, and manipulating media. 🧵 1/5
grant-witness.us/posts/2026-0...
grant-witness.us
February 10, 2026 at 4:18 PM
The Trump administration is planning to terminate $600M of CDC grants to CA, CO, MN, and IL. We're publishing the full list.
They are using vulnerable communities as a weapon to dismantle public health, targeting partisan enemies, and manipulating media. 🧵 1/5
grant-witness.us/posts/2026-0...
They are using vulnerable communities as a weapon to dismantle public health, targeting partisan enemies, and manipulating media. 🧵 1/5
grant-witness.us/posts/2026-0...
Reposted by Siegenthaler Lab
The purpose is to disincentivize investments in vaccine development
NEW: The F.D.A. refused to accept an application from Moderna for its mRNA flu vaccine.
Its reason: The agency did not think Moderna compared the new vaccine to one of the best flu shots available. The company spent $750M+ on a 41,000 person study.
www.nytimes.com/2026/02/10/h...
Its reason: The agency did not think Moderna compared the new vaccine to one of the best flu shots available. The company spent $750M+ on a 41,000 person study.
www.nytimes.com/2026/02/10/h...
F.D.A. Refuses to Review Moderna Flu Vaccine
www.nytimes.com
February 10, 2026 at 11:34 PM
The purpose is to disincentivize investments in vaccine development
Reposted by Siegenthaler Lab
Thrilled to share our latest work highlighting Bergmann glial development in the human cerebellum. @neurodevkathy.bsky.social @pnas.org
www.pnas.org/doi/10.1073/...
www.pnas.org/doi/10.1073/...
Spatiotemporal histogenesis of the developing human cerebellum reveals dynamic layering of Bergmann glia | PNAS
Bergmann glia (BG) are a specialized glial population essential for cerebellar development,
yet their developmental timeline and molecular identity...
www.pnas.org
February 10, 2026 at 11:15 PM
Thrilled to share our latest work highlighting Bergmann glial development in the human cerebellum. @neurodevkathy.bsky.social @pnas.org
www.pnas.org/doi/10.1073/...
www.pnas.org/doi/10.1073/...
Reposted by Siegenthaler Lab
Really beautiful work lead by @haldipur.bsky.social showing that we still have so much to learn about brain development! Notably, a lot of this work was done by a series of amazing University of Washington undergraduate students! Our next generation scientists! 💪🧠🔬😍
Thrilled to share our latest work highlighting Bergmann glial development in the human cerebellum. @neurodevkathy.bsky.social @pnas.org
www.pnas.org/doi/10.1073/...
www.pnas.org/doi/10.1073/...
Spatiotemporal histogenesis of the developing human cerebellum reveals dynamic layering of Bergmann glia | PNAS
Bergmann glia (BG) are a specialized glial population essential for cerebellar development,
yet their developmental timeline and molecular identity...
www.pnas.org
February 10, 2026 at 11:57 PM
Really beautiful work lead by @haldipur.bsky.social showing that we still have so much to learn about brain development! Notably, a lot of this work was done by a series of amazing University of Washington undergraduate students! Our next generation scientists! 💪🧠🔬😍
Reposted by Siegenthaler Lab
mRNA vaccine technology remains one of the greatest innovations in science that has happened in our live times. Nothing can change this fact and certainly not the FDA refusing to review a mRNA flu vaccine.
www.cnn.com/2026/02/10/h...
www.cnn.com/2026/02/10/h...
FDA refuses to review Moderna’s application for mRNA flu vaccine, company says | CNN
The US Food and Drug Administration has refused to accept an application from Moderna to review its first mRNA seasonal flu vaccine, the company said Tuesday, in another setback for the technology tha...
www.cnn.com
February 10, 2026 at 11:58 PM
mRNA vaccine technology remains one of the greatest innovations in science that has happened in our live times. Nothing can change this fact and certainly not the FDA refusing to review a mRNA flu vaccine.
www.cnn.com/2026/02/10/h...
www.cnn.com/2026/02/10/h...
Reposted by Siegenthaler Lab
Happy to share this new, very intentional chapter. I have left UCLA after 14 years to join the University of Colorado Anschutz as Professor of Biomedical Informatics and Neurosurgery and the inaugural Marsico Chair in Excellence in Functional Precision Medicine/n
news.cuanschutz.edu/dbmi/cu-ansc...
news.cuanschutz.edu/dbmi/cu-ansc...
CU Anschutz Recruits National Leader to Launch Functional Personalized Medicine Initiative
CU Anschutz welcomes Alice Soragni to launch a Functional Personalized Medicine Initiative using rapid tumor organoid testing to guide treatment decisions.
news.cuanschutz.edu
February 10, 2026 at 9:32 PM
Happy to share this new, very intentional chapter. I have left UCLA after 14 years to join the University of Colorado Anschutz as Professor of Biomedical Informatics and Neurosurgery and the inaugural Marsico Chair in Excellence in Functional Precision Medicine/n
news.cuanschutz.edu/dbmi/cu-ansc...
news.cuanschutz.edu/dbmi/cu-ansc...
Reposted by Siegenthaler Lab
Worth watching this in full. The statement is more powerful than this quote alone. Here is is from USA Today, with alt text.
Also! Rich Ruohonen is a personal injury lawyer and the oldest athlete to ever represent the United States in a Winter Games at 54 years old.
Also! Rich Ruohonen is a personal injury lawyer and the oldest athlete to ever represent the United States in a Winter Games at 54 years old.
February 10, 2026 at 10:12 PM
Worth watching this in full. The statement is more powerful than this quote alone. Here is is from USA Today, with alt text.
Also! Rich Ruohonen is a personal injury lawyer and the oldest athlete to ever represent the United States in a Winter Games at 54 years old.
Also! Rich Ruohonen is a personal injury lawyer and the oldest athlete to ever represent the United States in a Winter Games at 54 years old.
Reposted by Siegenthaler Lab
NEW: A newly updated reference manual for U.S. judges that provides answers to scientific and technical questions has eliminated some 90 pages about climate science.
It comes as numerous climate cases make their way through state and federal courts.
It comes as numerous climate cases make their way through state and federal courts.
Under GOP Pressure, Federal Agency Pulls Climate Change Chapter From Official Manual for U.S. Judges
The “Reference Manual on Scientific Evidence” — updated for the first time in 15 years — eliminates some 90 pages about climate science and comes just as numerous climate cases make their way through ...
www.propublica.org
February 10, 2026 at 8:16 PM
NEW: A newly updated reference manual for U.S. judges that provides answers to scientific and technical questions has eliminated some 90 pages about climate science.
It comes as numerous climate cases make their way through state and federal courts.
It comes as numerous climate cases make their way through state and federal courts.
Reposted by Siegenthaler Lab
This week marks a year since 10% of the CDC work force was fired. We are more vulnerable to the next pandemic,outbreak monitoring is crumbling, measles is basically endemic again,vaccine guidelines are now RFK Jr fan fiction.
All it took was one year.
All it took was one year.
February 10, 2026 at 10:26 PM
This week marks a year since 10% of the CDC work force was fired. We are more vulnerable to the next pandemic,outbreak monitoring is crumbling, measles is basically endemic again,vaccine guidelines are now RFK Jr fan fiction.
All it took was one year.
All it took was one year.
Reposted by Siegenthaler Lab
Report: Employers Created 40,000 New Jobs For Existing Employees Last Month https://theonion.com/report-employers-created-40-000-new-jobs-for-existing-1819575878/
February 10, 2026 at 7:00 PM
Report: Employers Created 40,000 New Jobs For Existing Employees Last Month https://theonion.com/report-employers-created-40-000-new-jobs-for-existing-1819575878/
Reposted by Siegenthaler Lab
Dozens of researchers will move to France from US following high-profile bid to lure talent. Large proportion worked at Columbia University, which had its grants cut and frozen by the administration of US President Donald Trump. www.nature.com/articles/d41...
Dozens of researchers will move to France from US following high-profile bid to lure talent
Large proportion worked at Columbia University, which had its grants cut and frozen by the administration of US President Donald Trump.
www.nature.com
February 10, 2026 at 5:27 PM
Dozens of researchers will move to France from US following high-profile bid to lure talent. Large proportion worked at Columbia University, which had its grants cut and frozen by the administration of US President Donald Trump. www.nature.com/articles/d41...
Reposted by Siegenthaler Lab
"One might say, 'I don’t care because that only happens to THOSE people.' Perhaps. But what if someone here legally, or even a United States citizen, is afforded no due process after being seized by mistake?... Or by a choice?
Fortunately, our Constitution demands more, including the rule of law.."
Fortunately, our Constitution demands more, including the rule of law.."
BONUS RULING: Judge Thomas Johnston, a George W. Bush appoiintee in West Virginia, used a recent ruling to warn of the dangers of defying due process for immigrants because of what it could also mean for Americans. It's worth a read.
storage.courtlistener.com/recap/gov.us...
storage.courtlistener.com/recap/gov.us...
February 10, 2026 at 3:38 PM
"One might say, 'I don’t care because that only happens to THOSE people.' Perhaps. But what if someone here legally, or even a United States citizen, is afforded no due process after being seized by mistake?... Or by a choice?
Fortunately, our Constitution demands more, including the rule of law.."
Fortunately, our Constitution demands more, including the rule of law.."
Reposted by Siegenthaler Lab
A new paper published in @jcb.org by postdoc Jorge Diaz from the Mayor lab at UCL shows that during collective migration, epithelial-like clusters generate traction force mainly through cryptic protrusions at the centre, while mesenchymal clusters do so at their periphery:
doi.org/10.1083/jcb....
doi.org/10.1083/jcb....
January 26, 2026 at 9:30 PM
A new paper published in @jcb.org by postdoc Jorge Diaz from the Mayor lab at UCL shows that during collective migration, epithelial-like clusters generate traction force mainly through cryptic protrusions at the centre, while mesenchymal clusters do so at their periphery:
doi.org/10.1083/jcb....
doi.org/10.1083/jcb....
Reposted by Siegenthaler Lab
So proud to share my paper on collective chemotaxis and force coordination in epithelial and mesenchymal cells, developed in the Mayor Lab and now published in JCB. Deeply grateful for everything I learned from Xenopus NC and the amphibian world, where adaptation is everything🐸
A new paper published in @jcb.org by postdoc Jorge Diaz from the Mayor lab at UCL shows that during collective migration, epithelial-like clusters generate traction force mainly through cryptic protrusions at the centre, while mesenchymal clusters do so at their periphery:
doi.org/10.1083/jcb....
doi.org/10.1083/jcb....
January 28, 2026 at 7:36 PM
So proud to share my paper on collective chemotaxis and force coordination in epithelial and mesenchymal cells, developed in the Mayor Lab and now published in JCB. Deeply grateful for everything I learned from Xenopus NC and the amphibian world, where adaptation is everything🐸
Reposted by Siegenthaler Lab
I woke up at 4:18 am and said, “we took all the friction out of the systems that poor people use to survive and gave rich people all the luxury of their frictionlessness.”
I will make it make sense later.
I will make it make sense later.
February 10, 2026 at 12:58 PM
I woke up at 4:18 am and said, “we took all the friction out of the systems that poor people use to survive and gave rich people all the luxury of their frictionlessness.”
I will make it make sense later.
I will make it make sense later.
Reposted by Siegenthaler Lab
We’re hiring: Research Group Leader in computational biology.
Are you generating more research ideas than you can explore? Lead cutting-edge AI & biology research at EMBL-EBI.
Apply by 11 April 2026: embl.wd103.myworkdayjobs.com/en-US/EMBL/j...
#ScienceCareers @ewaldlab.org @embl.org
Are you generating more research ideas than you can explore? Lead cutting-edge AI & biology research at EMBL-EBI.
Apply by 11 April 2026: embl.wd103.myworkdayjobs.com/en-US/EMBL/j...
#ScienceCareers @ewaldlab.org @embl.org
February 10, 2026 at 11:31 AM
We’re hiring: Research Group Leader in computational biology.
Are you generating more research ideas than you can explore? Lead cutting-edge AI & biology research at EMBL-EBI.
Apply by 11 April 2026: embl.wd103.myworkdayjobs.com/en-US/EMBL/j...
#ScienceCareers @ewaldlab.org @embl.org
Are you generating more research ideas than you can explore? Lead cutting-edge AI & biology research at EMBL-EBI.
Apply by 11 April 2026: embl.wd103.myworkdayjobs.com/en-US/EMBL/j...
#ScienceCareers @ewaldlab.org @embl.org
Reposted by Siegenthaler Lab
Super Bowl viewers Sunday speculated that 5-year-old Liam Conejo Ramos appeared in the halftime show. In fact, he has been in hiding with his family.
“He can’t sleep well at night. He wakes up three or four times a night screaming, ‘Daddy, Daddy,’” Liam's father Adrian Conejo Arias, said.
“He can’t sleep well at night. He wakes up three or four times a night screaming, ‘Daddy, Daddy,’” Liam's father Adrian Conejo Arias, said.
‘He’s not the same’: Father of Liam Conejo Ramos says 5-year-old continues to suffer
Some people thought they say the 5-year-old during the Super Bowl halftime show. But Liam is still in hiding with his family, after he and his father were detained and then released from a Texas deten...
www.mprnews.org
February 10, 2026 at 1:11 AM
Super Bowl viewers Sunday speculated that 5-year-old Liam Conejo Ramos appeared in the halftime show. In fact, he has been in hiding with his family.
“He can’t sleep well at night. He wakes up three or four times a night screaming, ‘Daddy, Daddy,’” Liam's father Adrian Conejo Arias, said.
“He can’t sleep well at night. He wakes up three or four times a night screaming, ‘Daddy, Daddy,’” Liam's father Adrian Conejo Arias, said.
Reposted by Siegenthaler Lab
'Here, we discover functional adaptation of resident lymphocytes within two distinct skin stem cell niches and show that through this communication, each niche adjusts to meet diverse tissue demands.'
#Preprint #Immunology
www.biorxiv.org/content/10.6...
#Preprint #Immunology
www.biorxiv.org/content/10.6...
www.biorxiv.org
February 10, 2026 at 12:04 PM
'Here, we discover functional adaptation of resident lymphocytes within two distinct skin stem cell niches and show that through this communication, each niche adjusts to meet diverse tissue demands.'
#Preprint #Immunology
www.biorxiv.org/content/10.6...
#Preprint #Immunology
www.biorxiv.org/content/10.6...
Reposted by Siegenthaler Lab
Regional #snowpack and #streamflow volume forecasts are extremely low. Record-low statewide snowpack conditions exist in Colorado and Utah, while Wyoming statewide SWE is 84% of average.
Learn more: wwa.colorado.edu/resources/in... #wx #weather @cires.colorado.edu
Learn more: wwa.colorado.edu/resources/in... #wx #weather @cires.colorado.edu
February 9, 2026 at 10:38 PM
Regional #snowpack and #streamflow volume forecasts are extremely low. Record-low statewide snowpack conditions exist in Colorado and Utah, while Wyoming statewide SWE is 84% of average.
Learn more: wwa.colorado.edu/resources/in... #wx #weather @cires.colorado.edu
Learn more: wwa.colorado.edu/resources/in... #wx #weather @cires.colorado.edu
Reposted by Siegenthaler Lab
Brandi Carlile's accompaniment for "America the Beautiful" before the game last night was SistaStrings. The duo, Chauntee and Monique Ross, played another American anthem, "Lift Every Voice and Sing," on the Library's Stradivarius instruments in 2024.
Here's a clip of that impromptu performance. ⬇️
Here's a clip of that impromptu performance. ⬇️
February 9, 2026 at 6:55 PM
Brandi Carlile's accompaniment for "America the Beautiful" before the game last night was SistaStrings. The duo, Chauntee and Monique Ross, played another American anthem, "Lift Every Voice and Sing," on the Library's Stradivarius instruments in 2024.
Here's a clip of that impromptu performance. ⬇️
Here's a clip of that impromptu performance. ⬇️