A. Reza Mehdipour
@rezamehdipour.bsky.social
Assist. Prof. Molecular Modelling
Ghent University
#Protein dynamics #MD simulation
Membrane proteins transporters
Ghent University
#Protein dynamics #MD simulation
Membrane proteins transporters
Pinned
We are excited to announce the first in-cell structure of a LINC complex within a native nuclear envelope at subnanometer resolution!! #In-cell cryo-ET + #atomistic MD simulations! @tomdendooven.bsky.social et al!!
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by A. Reza Mehdipour
🧪How does an ABC transporter 'know' nucleotides & substrates bound to far apart binding sites? Using 1H15N, 19F NMR, HDX-MS, PET-FCS & activity assays with Neuweiler, Marcoux, Orelle & Jault labs, we found a communication hinge! 😍🥳
@microverse.bsky.social @lifeprofile.bsky.social
rdcu.be/ePm4C
@microverse.bsky.social @lifeprofile.bsky.social
rdcu.be/ePm4C
Bidirectional communication between nucleotide and substrate binding sites in a type IV multidrug ABC transporter
Nature Communications - The communication hinge, found in type IV ABC transporters, forms a bidirectional communication between ATP- and substrate-binding sites. This is an unexplored allosteric...
rdcu.be
November 12, 2025 at 11:15 AM
🧪How does an ABC transporter 'know' nucleotides & substrates bound to far apart binding sites? Using 1H15N, 19F NMR, HDX-MS, PET-FCS & activity assays with Neuweiler, Marcoux, Orelle & Jault labs, we found a communication hinge! 😍🥳
@microverse.bsky.social @lifeprofile.bsky.social
rdcu.be/ePm4C
@microverse.bsky.social @lifeprofile.bsky.social
rdcu.be/ePm4C
Reposted by A. Reza Mehdipour
if you see this post, your actions are:
- if you have a spare buck, give it to Wikipedia, then repost this
- if you don't have a spare buck, just repost
your action is mandatory for the world's best source of information to survive
- if you have a spare buck, give it to Wikipedia, then repost this
- if you don't have a spare buck, just repost
your action is mandatory for the world's best source of information to survive
I’ve never donated to Wikipedia before but I set up a small monthly donation as a fuck you to the world’s richest psychopath.
Elon Musk takes aim at Wikipedia
Musk has denounced Wikipedia as "Wokepedia" on X and urged people not to donate to the platform.
www.newsweek.com
December 26, 2024 at 12:03 PM
if you see this post, your actions are:
- if you have a spare buck, give it to Wikipedia, then repost this
- if you don't have a spare buck, just repost
your action is mandatory for the world's best source of information to survive
- if you have a spare buck, give it to Wikipedia, then repost this
- if you don't have a spare buck, just repost
your action is mandatory for the world's best source of information to survive
Reposted by A. Reza Mehdipour
🚨🧠🔬 A major breakthrough in molecular neuroscience:
I am excited to share a new story from our lab, published in accelerated format today by @nature.com:
"Delta-type glutamate receptors are ligand-gated ion channels"
Read more here (free article link): rdcu.be/eGIKz
I am excited to share a new story from our lab, published in accelerated format today by @nature.com:
"Delta-type glutamate receptors are ligand-gated ion channels"
Read more here (free article link): rdcu.be/eGIKz
September 16, 2025 at 4:47 PM
🚨🧠🔬 A major breakthrough in molecular neuroscience:
I am excited to share a new story from our lab, published in accelerated format today by @nature.com:
"Delta-type glutamate receptors are ligand-gated ion channels"
Read more here (free article link): rdcu.be/eGIKz
I am excited to share a new story from our lab, published in accelerated format today by @nature.com:
"Delta-type glutamate receptors are ligand-gated ion channels"
Read more here (free article link): rdcu.be/eGIKz
Reposted by A. Reza Mehdipour
We are hiring a Postdoc in membrane protein cryo-EM at the University of Georgia. Looking for candidates with expertise in membrane protein purification and biochemistry. Fully funded for up to 5 years. Join us in Athens, GA. Apply: camilo.perez@uga.edu
August 21, 2025 at 2:26 PM
We are hiring a Postdoc in membrane protein cryo-EM at the University of Georgia. Looking for candidates with expertise in membrane protein purification and biochemistry. Fully funded for up to 5 years. Join us in Athens, GA. Apply: camilo.perez@uga.edu
Reposted by A. Reza Mehdipour
It's horrific what's happening in Gaza right now and nobody talks about it on this platform
August 21, 2025 at 3:02 PM
It's horrific what's happening in Gaza right now and nobody talks about it on this platform
Reposted by A. Reza Mehdipour
I wish people would stop talking about international law like it's a real thing
August 17, 2025 at 1:15 PM
I wish people would stop talking about international law like it's a real thing
Reposted by A. Reza Mehdipour
We are excited to announce the first in-cell structure of a LINC complex within a native nuclear envelope at subnanometer resolution!! #In-cell cryo-ET + #atomistic MD simulations! @tomdendooven.bsky.social et al!!
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
August 5, 2025 at 12:41 PM
We are excited to announce the first in-cell structure of a LINC complex within a native nuclear envelope at subnanometer resolution!! #In-cell cryo-ET + #atomistic MD simulations! @tomdendooven.bsky.social et al!!
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by A. Reza Mehdipour
Photo of the Day.
Israel threatened reprisals if the press filmed Gaza from above during airdrops.
This is why. A scene of destroyed & burnt out buildings in what is left of Gaza City, the pre-war home to 800,000 people.
Credit to Post photographer Heidi Levine who defied the ban & took this.
Israel threatened reprisals if the press filmed Gaza from above during airdrops.
This is why. A scene of destroyed & burnt out buildings in what is left of Gaza City, the pre-war home to 800,000 people.
Credit to Post photographer Heidi Levine who defied the ban & took this.
August 1, 2025 at 10:09 PM
Photo of the Day.
Israel threatened reprisals if the press filmed Gaza from above during airdrops.
This is why. A scene of destroyed & burnt out buildings in what is left of Gaza City, the pre-war home to 800,000 people.
Credit to Post photographer Heidi Levine who defied the ban & took this.
Israel threatened reprisals if the press filmed Gaza from above during airdrops.
This is why. A scene of destroyed & burnt out buildings in what is left of Gaza City, the pre-war home to 800,000 people.
Credit to Post photographer Heidi Levine who defied the ban & took this.
Reposted by A. Reza Mehdipour
Dear all, we are looking for a research assistant in protein biochemistry / cell biology to support our work on nuclear reshaping in human cells. Here the link to the call, please spread: mrc.tal.net/vx/mobile-0/...
Research Support Officer - Structural Studies - Dr Matteo Allegretti - LMB 2674 - Medical Research Council
Location: Cambridge. Vacancy: Research Support Officer - Structural Studies - Dr Matteo Allegretti - LMB 2674. Closing Date: 31/08/2025, 23:55
mrc.tal.net
August 1, 2025 at 11:48 AM
Dear all, we are looking for a research assistant in protein biochemistry / cell biology to support our work on nuclear reshaping in human cells. Here the link to the call, please spread: mrc.tal.net/vx/mobile-0/...
Reposted by A. Reza Mehdipour
Palestinian activist Odeh Hadalin (a.k.a. Awdah Hathaleen), who was featured in the Oscar-winning documentary No Other Land, was shot to death in the West Bank on Monday.
'No Other Land' Contributor Odeh Hadalin Killed in West Bank Settler Attack
Odeh Hadalin, a contributor to the Oscar-winning documentary 'No Other Land,' was reportedly killed in an attack by Israeli settlers in the West Bank.
www.rollingstone.com
July 29, 2025 at 6:03 PM
Palestinian activist Odeh Hadalin (a.k.a. Awdah Hathaleen), who was featured in the Oscar-winning documentary No Other Land, was shot to death in the West Bank on Monday.
Reposted by A. Reza Mehdipour
this is what beit hanoun looked like (from arabi21.com/story/155862...)
July 27, 2025 at 3:14 PM
this is what beit hanoun looked like (from arabi21.com/story/155862...)
Reposted by A. Reza Mehdipour
having blown up all the hospitals in Gaza and normalised killing starving people who are queuing for food, this: killing women and children queuing for supplements at a medical centre.
www.abc.net.au/news/2025-07...
www.abc.net.au/news/2025-07...
Women and children among 15 killed in Gaza medical centre strike
Health authorities in Gaza have accused Israeli forces of killing women and children queuing for supplements and medicine near a medical centre in the strip.
www.abc.net.au
July 11, 2025 at 2:10 AM
having blown up all the hospitals in Gaza and normalised killing starving people who are queuing for food, this: killing women and children queuing for supplements at a medical centre.
www.abc.net.au/news/2025-07...
www.abc.net.au/news/2025-07...
Reposted by A. Reza Mehdipour
The occupation admitting to war crimes
Israel’s Defense Minister confirms the Israeli strike on Iran’s state broadcaster.
He writes: “The Iranian regime’s propaganda and incitement broadcasting authority was attacked by the IDF.”
He writes: “The Iranian regime’s propaganda and incitement broadcasting authority was attacked by the IDF.”
June 16, 2025 at 6:44 PM
The occupation admitting to war crimes
Reposted by A. Reza Mehdipour
Israel's attack on Iran, yet another demonstration of its contempt for international law, was also a smokescreen for yet another step in the ethnic cleansing and annexation of the West Bank. Israel is laughing in the face of the West's fake support of the 2 state solution
June 13, 2025 at 7:56 AM
Israel's attack on Iran, yet another demonstration of its contempt for international law, was also a smokescreen for yet another step in the ethnic cleansing and annexation of the West Bank. Israel is laughing in the face of the West's fake support of the 2 state solution
Reposted by A. Reza Mehdipour
Babies can only have milk. They can’t even have water. Since Israel is banning all aid including baby formula, these babies will die. And since Israel is also starving everyone in Gaza, moms can’t nurse their babies either. They’re just watching their babies die as they die to.
14,000 babies are at risk of dying in the next 48 hours in Gaza if aid doesn’t reach them, warns Tom Fletcher, the UN’s under-secretary-general for humanitarian affairs – a figure he called “utterly chilling.”
🔴 LIVE updates: aje.io/x26ghx
🔴 LIVE updates: aje.io/x26ghx
May 20, 2025 at 2:08 PM
Babies can only have milk. They can’t even have water. Since Israel is banning all aid including baby formula, these babies will die. And since Israel is also starving everyone in Gaza, moms can’t nurse their babies either. They’re just watching their babies die as they die to.
Reposted by A. Reza Mehdipour
Reposted by A. Reza Mehdipour
So, for those killed and those whose voices are silenced: what more evidence do you need?
Will you act now – decisively – to prevent genocide in Gaza and to ensure respect for international humanitarian law?
This Council must prevail. Demand this ends.
Will you act now – decisively – to prevent genocide in Gaza and to ensure respect for international humanitarian law?
This Council must prevail. Demand this ends.
May 14, 2025 at 2:03 AM
So, for those killed and those whose voices are silenced: what more evidence do you need?
Will you act now – decisively – to prevent genocide in Gaza and to ensure respect for international humanitarian law?
This Council must prevail. Demand this ends.
Will you act now – decisively – to prevent genocide in Gaza and to ensure respect for international humanitarian law?
This Council must prevail. Demand this ends.
Finally, it's out in Nat Commun! Excellent collaboration with my colleagues and friends in Frankfurt, especially @ihaenelt.bsky.social and Janet Vonck.
This work demonstrates the role of the intrinsically disordered N-terminus of KtrAB in channel opening.
Full story here: rdcu.be/elDYO
This work demonstrates the role of the intrinsically disordered N-terminus of KtrAB in channel opening.
Full story here: rdcu.be/elDYO
A short intrinsically disordered region at KtrB’s N-terminus facilitates allosteric regulation of K+ channel KtrAB
Nature Communications - KtrAB is a major potassium uptake system that has been linked to the pathogenesis of many infectious bacteria. Here the authors show that KtrB from Vibrio alginolyticus...
rdcu.be
May 12, 2025 at 9:34 AM
Finally, it's out in Nat Commun! Excellent collaboration with my colleagues and friends in Frankfurt, especially @ihaenelt.bsky.social and Janet Vonck.
This work demonstrates the role of the intrinsically disordered N-terminus of KtrAB in channel opening.
Full story here: rdcu.be/elDYO
This work demonstrates the role of the intrinsically disordered N-terminus of KtrAB in channel opening.
Full story here: rdcu.be/elDYO
Reposted by A. Reza Mehdipour
Opinion from the FT's Editorial Board: 'The US and European countries that tout Israel as an ally that shares their values have issued barely a word of condemnation. They should be ashamed of their silence, and stop enabling Netanyahu to act with impunity.' www.ft.com/content/f5fd...
May 7, 2025 at 3:16 PM
Opinion from the FT's Editorial Board: 'The US and European countries that tout Israel as an ally that shares their values have issued barely a word of condemnation. They should be ashamed of their silence, and stop enabling Netanyahu to act with impunity.' www.ft.com/content/f5fd...
Reposted by A. Reza Mehdipour
Pre-announcement: MARTINI tutorial workshop, August 11-15th 2025 in Groningen, The Netherlands !!
Learn basic and advanced Martini from the cocktail masters themselves. Registration will open soon.
Learn basic and advanced Martini from the cocktail masters themselves. Registration will open soon.
April 28, 2025 at 9:06 AM
Pre-announcement: MARTINI tutorial workshop, August 11-15th 2025 in Groningen, The Netherlands !!
Learn basic and advanced Martini from the cocktail masters themselves. Registration will open soon.
Learn basic and advanced Martini from the cocktail masters themselves. Registration will open soon.
Reposted by A. Reza Mehdipour
Dear all,
I am very excited about the upcoming 842 WE-Heraeus-Seminar #Cryo-EM on the Move. @djanuliene.bsky.social and I are looking forward to a great conference with many exciting speakers!
I am very excited about the upcoming 842 WE-Heraeus-Seminar #Cryo-EM on the Move. @djanuliene.bsky.social and I are looking forward to a great conference with many exciting speakers!
April 28, 2025 at 9:09 AM
Dear all,
I am very excited about the upcoming 842 WE-Heraeus-Seminar #Cryo-EM on the Move. @djanuliene.bsky.social and I are looking forward to a great conference with many exciting speakers!
I am very excited about the upcoming 842 WE-Heraeus-Seminar #Cryo-EM on the Move. @djanuliene.bsky.social and I are looking forward to a great conference with many exciting speakers!
Reposted by A. Reza Mehdipour
Happy April 1st with Bax, Max and Zax in JACS
April 1, 2025 at 9:20 PM
Happy April 1st with Bax, Max and Zax in JACS
Reposted by A. Reza Mehdipour
We are looking for a PhD candidate in molecular biology / biochemistry / chemical biology with a passion for drug discovery to join our young and enthusiastic team @univie.ac.at. For details, visit: vds-phanuspo.univie.ac.at/application/.... Reposts are very much appreciated!
March 21, 2025 at 2:51 PM
We are looking for a PhD candidate in molecular biology / biochemistry / chemical biology with a passion for drug discovery to join our young and enthusiastic team @univie.ac.at. For details, visit: vds-phanuspo.univie.ac.at/application/.... Reposts are very much appreciated!
Reposted by A. Reza Mehdipour
Excited about structural biology & chemical ecology?!? We are looking for PhD/PD researchers for two collaborative projects with @yukoulrich.bsky.social l & @oconnorlab.bsky.social
🦠🌱🐜🧪
The 2025 project call with the IMPRS of the @mpi-ce.bsky.social is out! www.ice.mpg.de/296548/curre...
🦠🌱🐜🧪
The 2025 project call with the IMPRS of the @mpi-ce.bsky.social is out! www.ice.mpg.de/296548/curre...
Current Call
www.ice.mpg.de
March 13, 2025 at 2:56 PM
Excited about structural biology & chemical ecology?!? We are looking for PhD/PD researchers for two collaborative projects with @yukoulrich.bsky.social l & @oconnorlab.bsky.social
🦠🌱🐜🧪
The 2025 project call with the IMPRS of the @mpi-ce.bsky.social is out! www.ice.mpg.de/296548/curre...
🦠🌱🐜🧪
The 2025 project call with the IMPRS of the @mpi-ce.bsky.social is out! www.ice.mpg.de/296548/curre...