Rafael D. Acemel
rdacemel.bsky.social
Rafael D. Acemel
@rdacemel.bsky.social
Researcher at Centro Andaluz de Biología del Desarrollo (Sevilla/Spain). Trying to apply genomics to understand things about gene regulation and Evo-Devo.
Reposted by Rafael D. Acemel
📢 We are hiring!
👩🏾‍⚕️Research technician/Lab manager
📍 @cabd-upo-csic.bsky.social , Sevilla, Spain
🧬 Gene regulation in animal development & evolution

Check the details 👇 & join us!
drive.google.com/file/d/1cZJi...

#ResearchTechnician #Zebrafish #GeneRegulation #DevelopmentalBiology
October 15, 2025 at 3:00 PM
I think everybody knows but Adri is awesome!
🚨JOB ALERT🚨

FRIENDS PLEASE SPREAD and RT

We are building a small expert team within the @bokelab.bsky.social at @crg.eu @prbb.org to investigate fundamental questions in oocyte cell biology, focusing on how proteostasis regulation influences dormancy and fertility.

See below 2 calls👇
October 2, 2025 at 12:34 PM
Very much honoured and excited with the opportunity.
October 1, 2025 at 1:26 PM
Reposted by Rafael D. Acemel
¡¡ATENCIÓN!! Esta semana comienza una nueva edición de #CienciaenelBar de la @unisevilla.bsky.social 🤩 Este curso nos encontraréis en la Sala El Cachorro

cienciabar.wordpress.com/.../comenzam...

#DivulgaUS
September 29, 2025 at 9:59 AM
Reposted by Rafael D. Acemel
Happy to share the Biodiversity Cell Atlas white paper, out today in @nature.com. We look at the possibilities, challenges, and potential impacts of molecularly mapping cells across the tree of life.
www.nature.com/articles/s41...
September 24, 2025 at 3:12 PM
Excited to post my first #JobOffer! I am looking for a research technician to help me build new projects from the grounds up at @cabd-upo-csic.bsky.social
We will use medaka to study how organs can be reprogrammed!
Details on how to apply below 👇
#JobOffer #ScienceJobs #EvoDevo #GeneRegulation
September 19, 2025 at 8:53 AM
Reposted by Rafael D. Acemel
🎉 Another exciting contribution from our lab this summer!

🧬 Nearly complete, gapless genome of the sex-changing central bearded dragon (Pogona vitticeps) shed new light on the mystery of reptile sex determination.

Proud to be part of this collaborative effort!

academic.oup.com/gigascience/...
A near telomere-to-telomere phased genome assembly and annotation for the Australian central bearded dragon Pogona vitticeps
AbstractBackground. The central bearded dragon (Pogona vitticeps) is widely distributed in central eastern Australia and adapts readily to captivity. Among
academic.oup.com
August 19, 2025 at 11:21 PM
Everything starts with few cells and big hopes 🙂
September 10, 2025 at 12:00 PM
Amazing Lab and topic!!
We are looking for a student to continue our work on chromatin evolution:
www.nature.com/articles/s41...
www.biorxiv.org/content/10.1...

The project with @seanamontgomery.bsky.social will focus on chromatin state readers across eukaryotes.

More info: recruitment.crg.eu/content/jobs...
September 5, 2025 at 10:04 AM
Reposted by Rafael D. Acemel
Les temperatures extremes alteren la reproducció de les espècies www.uab.cat/web/sala-de-...
Les temperatures extremes alteren la reproducció de les espècies
Investigadores de la UAB han demostrat que la calor extrema pot canviar el destí genètic d’una espècie. Resultats publicats recentment indiquen...
www.uab.cat
September 4, 2025 at 12:57 PM
Reposted by Rafael D. Acemel
Update of our preprint on Inter-individual gene expression variability in fishes! We improved statistical analyses of continuous variables, and especially added machine learning on promoters which confirms cis-regulation of organ-specific expression variability, under stronger sequence […]
Original post on ecoevo.social
ecoevo.social
September 3, 2025 at 12:15 PM
Reposted by Rafael D. Acemel
🚨 We are hiring!
🧬 PhD Position – Genomic Architecture & Evolution
Join our team at UAB (Barcelona) in an international project
🔬 4-year FPI contract
🎓 Biology/Genetics background + Master’s + English
📅 Apply by Sept 30, 2025
📧 aurora.ruizherrera@uab.cat
🔗 grupsderecerca.uab.cat/evolgenom
September 3, 2025 at 11:45 AM
Reposted by Rafael D. Acemel
1) I am delighted to present this terrific tour de force research conducted by my post-doc Dr. Gayani Senevirathne @gayani.bsky.social and published today in Nature -
www.nature.com/articles/s41...
The evolution of hominin bipedalism in two steps - Nature
The human pelvis exhibits distinct spatiotemporal ossification patterns and an ilium cartilage growth plate that is shifted perpendicularly compared with those of other mammals and non-human primates—...
www.nature.com
August 27, 2025 at 3:13 PM
Reposted by Rafael D. Acemel
Great start of the #CABDseminars 2025/2026 with the talk of Miguel Rodriguez de los Santos!

Dr. Rodriguez gave an insight of the studies from his PhD and Postdoc work focused on rate diseases. He was invited by @crisprscan.bsky.social!

Thanks for coming Miguel!
August 26, 2025 at 3:26 PM
Reposted by Rafael D. Acemel
Teaching biology in the old days relied on large posters. Often beautiful and poetic art pieces. When a chair of @genevunige.bsky.social dept, in Geneva, we digitalised our huge collection (catalogue raisonné). Why? I dont' know. The strange feeling these things should not disappear. Yet they will.
August 25, 2025 at 7:44 AM
Reposted by Rafael D. Acemel
A genome sequence and single-cell atlas of a marine worm species point towards bursts of gene emergence, duplication and loss as the drivers of lineage-specific body traits

go.nature.com/4oAI2nf
The perplexing body plan of arrow worms decoded
A genome sequence and single-cell atlas of a marine worm species point towards bursts of gene emergence, duplication and loss as the drivers of lineage-specific body traits.
go.nature.com
August 13, 2025 at 4:04 PM
Reposted by Rafael D. Acemel
PRC2 silences genes by adding H3K27me3 at the right spots in the genome. Our model shows how the nucleic acid-binding domain (NBD) of SUZ12 keeps this activity under control, and what happens when you remove it.
August 13, 2025 at 9:54 PM
Reposted by Rafael D. Acemel
Pleased to see this study out, combining experimental work from our lab at the @cbitoulouse.bsky.social, in particular by @nathaliebastie.bsky.social and @beckof.bsky.social, and from Laura Chaptal and @alengronne.bsky.social at IGH Montpellier
@cnrs.fr @cnrsbiologie.bsky.social

Congrats to all!
RNA Pol II-based regulations of chromosome folding
How transcription and cohesin complexes interact to regulate 3D genome organization remains unclear. Chapard et al. dissect their respective contributions and their interplay in shaping the genome arc...
www.cell.com
August 9, 2025 at 10:47 AM
Reposted by Rafael D. Acemel
Evolution’s eye game is wild, but mollusks take it to another level

CRISPR in apple snails gives us a new model to dissect how nature rebuilds complex organs like the camera-type eyes we humans possess

It turns out Evolution doesn’t just innovate, it rewinds, remixes, & regenerates

rdcu.be/ezw0t
A genetically tractable non-vertebrate system to study complete camera-type eye regeneration
Nature Communications - Accorsi et al. show that the apple snail Pomacea canaliculata has eyes similar to humans and can fully regenerate them. They then developed genetic tools to establish these...
url.us.m.mimecastprotect.com
August 6, 2025 at 11:21 AM
Reposted by Rafael D. Acemel
Happy to share our new preprint on lens morphogenesis in ocular organoids. All thanks to Elin Stahl, Miguel Angel Delgado-Toscano, Ishwariya Saravanan, Anastasija Paneva and Jochen Wittbrodt @wittbrodtlab.bsky.social

www.biorxiv.org/content/10.1...
April 23, 2025 at 9:19 PM
Reposted by Rafael D. Acemel
Pretty surreal to see my artwork on the cover of Nature Genetics! Big congrats to @julianeg.bsky.social, @stemundi.bsky.social and the others, and thank you Juliane for letting me help bring your research to life visually.

www.nature.com/ng/volumes/5...
July 23, 2025 at 8:06 AM
Reposted by Rafael D. Acemel
Thrilled to share that our latest work on marsupial heterochrony is now online at @cp-devcell.bsky.social @cellpress.bsky.social @lab-turner.bsky.social @crick.ac.uk We used scRNAseq to understand the asynchronous progression of developmental programmes in marsupials www.cell.com/developmenta...
Marsupial single-cell transcriptomics identifies temporal diversity in mammalian developmental programs
Menchero et al. generate a single-cell transcriptomic atlas in the opossum and show rapid progression of transcriptional programs in specific tissues relative to morphological landmarks. This shift in...
www.cell.com
July 24, 2025 at 5:07 PM
Reposted by Rafael D. Acemel
our work on the molecular differences between transcription factor isoforms is out now in Molecular Cell!

key point: 2/3rds of TF isos differ in properties like DNA binding & transcriptional activity

many are "negative regulators" & misexpressed in cancer

www.sciencedirect.com/science/arti...
March 26, 2025 at 5:11 PM
Reposted by Rafael D. Acemel
Honored to receive the City Medal 🎖️ of Algeciras, my hometown.

Thanks to all group members, past and present, who make our research possible. Also mentors, institutions and funding agencies for support.

I hope this will stimulate further generations to follow the path of discovery and innovation.
March 18, 2025 at 9:51 AM