David Garfield
@dagarfield.bsky.social
That same guy from Twitter/X
Congrats to Jonas on the pre-print of his primary thesis work!
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
The Establishment of Cell-Type Specific Gene Regulation in the Sea Urchin Embryo
Cell-fate commitment in metazoan development relies on precise gene regulatory programs. This study presents a comprehensive single-cell atlas of gene expression (scRNA-seq), nascent transcription (sc...
www.biorxiv.org
August 13, 2025 at 7:49 PM
Congrats to Jonas on the pre-print of his primary thesis work!
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
I don't know about you, but I enjoyed President Musk's first oval office press conference. He even brought his kid and some sort of orange puppet to entertain him. He's a nice dad.
February 12, 2025 at 4:23 AM
I don't know about you, but I enjoyed President Musk's first oval office press conference. He even brought his kid and some sort of orange puppet to entertain him. He's a nice dad.
Reposted by David Garfield
1. Today the NIH director issued a new directive slashing overhead rates to 15%.
I want to provide some context on what that means and why it matters.
grants.nih.gov/grants/guide...
I want to provide some context on what that means and why it matters.
grants.nih.gov/grants/guide...
NOT-OD-25-068: Supplemental Guidance to the 2024 NIH Grants Policy Statement: Indirect Cost Rates
NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Supplemental Guidance to the 2024 NIH Grants Policy Statement: Indirect Cost Rates NOT-OD-25-068. OD
grants.nih.gov
February 8, 2025 at 12:18 AM
1. Today the NIH director issued a new directive slashing overhead rates to 15%.
I want to provide some context on what that means and why it matters.
grants.nih.gov/grants/guide...
I want to provide some context on what that means and why it matters.
grants.nih.gov/grants/guide...
My child really eats only avocados and berries. This is going to suck....
February 2, 2025 at 11:34 PM
My child really eats only avocados and berries. This is going to suck....
Please consider taking Anshul up on his offer. Many of us are waiting for the results of this cool project ;)
Would be happy to be a faculty mentor for PD candidates with interests in our labs work. We're building a foundation of 10,000s of highly interpretable, robust, efficient deep learning models of multiple layers of gene regulation across fetal and adult cell states. 1/
Applications for the FutureHouse Independent Postdoctoral Fellowship are due in two weeks! $125k annual stipend, full access to our resources, be coadvised by world class professors and apply our AI science agents to make new discoveries. Apply!
Details here: www.futurehouse.org/fellowship
Details here: www.futurehouse.org/fellowship
January 31, 2025 at 4:17 PM
Please consider taking Anshul up on his offer. Many of us are waiting for the results of this cool project ;)
Did you think you were too late for a cool summer internship? Think again! 12 weeks of awesomeness on aging and partial reprogramming working with some great post-docs from the Jasper and Marioni labs at Genentech.
roche.wd3.myworkdayjobs.com/ROG-A2O-GENE...
roche.wd3.myworkdayjobs.com/ROG-A2O-GENE...
2025 Summer Intern - Regenerative Medicine
2025 Summer Intern - Regenerative Medicine Department Summary As part of Genentech Research & Early Development (gRED), the department of Regenerative Medicine is at the forefront of developing no...
roche.wd3.myworkdayjobs.com
January 31, 2025 at 4:17 PM
Did you think you were too late for a cool summer internship? Think again! 12 weeks of awesomeness on aging and partial reprogramming working with some great post-docs from the Jasper and Marioni labs at Genentech.
roche.wd3.myworkdayjobs.com/ROG-A2O-GENE...
roche.wd3.myworkdayjobs.com/ROG-A2O-GENE...
You know, when the AI comes for our jobs, people who can manipulate little marine creatures with actual tools will be the last people left with jobs....man career advice got weird these last few years.
January 24, 2025 at 9:42 PM
You know, when the AI comes for our jobs, people who can manipulate little marine creatures with actual tools will be the last people left with jobs....man career advice got weird these last few years.
Its paid summer intern time!
Come join us for a summer of ML, regulatory genomics, and human genetics. Also maybe a crazy idea involving neanderthals.
roche.wd3.myworkdayjobs.com/ROG-A2O-GENE...
Come join us for a summer of ML, regulatory genomics, and human genetics. Also maybe a crazy idea involving neanderthals.
roche.wd3.myworkdayjobs.com/ROG-A2O-GENE...
2025 Summer Intern - Biology Research | AI Development and gCS Immunology
Department Summary At Genentech Research & Early Development (gRED) we have initiated an exciting journey to bring together and further strengthen our computational talent and capabilities by form...
roche.wd3.myworkdayjobs.com
December 6, 2024 at 8:37 PM
Its paid summer intern time!
Come join us for a summer of ML, regulatory genomics, and human genetics. Also maybe a crazy idea involving neanderthals.
roche.wd3.myworkdayjobs.com/ROG-A2O-GENE...
Come join us for a summer of ML, regulatory genomics, and human genetics. Also maybe a crazy idea involving neanderthals.
roche.wd3.myworkdayjobs.com/ROG-A2O-GENE...
Come. Spend a summer interning with us. We'll even pay you to do it.
roche.wd3.myworkdayjobs.com/ROG-A2O-GENE...
roche.wd3.myworkdayjobs.com/ROG-A2O-GENE...
December 1, 2023 at 9:21 PM
Come. Spend a summer interning with us. We'll even pay you to do it.
roche.wd3.myworkdayjobs.com/ROG-A2O-GENE...
roche.wd3.myworkdayjobs.com/ROG-A2O-GENE...
Gotta say, nothing brings back the pain of opportunities missed like seeing the rounds of fall academic job openings.
November 9, 2023 at 4:46 AM
Gotta say, nothing brings back the pain of opportunities missed like seeing the rounds of fall academic job openings.
Two excellent pre-prints today reminding us how hard it can be to translate genetic findings to the clinic (but still excellent work ;) )
www.biorxiv.org/content/10.1...
and
www.medrxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
and
www.medrxiv.org/content/10.1...
October 13, 2023 at 3:16 PM
Two excellent pre-prints today reminding us how hard it can be to translate genetic findings to the clinic (but still excellent work ;) )
www.biorxiv.org/content/10.1...
and
www.medrxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
and
www.medrxiv.org/content/10.1...
Reposted by David Garfield
Katalin Karikó on the status economy of academia. She’s the hero we don’t deserve.
Source: josephnoelwalker.com/147-katalin-...
Source: josephnoelwalker.com/147-katalin-...
![There is a “centre” where the money, the fame, is; most likely your proposal gets funded because it’s on the most favourable topic. Maybe today, RNA is [most favourable]. If you are working with mRNA, maybe that's the centre there.
And then there are people in the periphery. There is no fame, there is no money, no nothing there. The only thing in the periphery is freedom. You can do what you like to do, what you feel is important.
Here’s what a proposal is: why they should give me money. And they should question that. “She came from university nobody knew about.” “She never had a mentor who was famous.”
And somehow it gravitates always to the same people, same circle. They get published there, they get the money. And that's another explanation: I was not famous enough or didn't have anybody who would support me in a way that somebody that’s a famous and well-established scientist stands behind you and says, “Oh, look at this, it’s good.”](https://cdn.bsky.app/img/feed_thumbnail/plain/did:plc:h6srr75ahvugj6gts7ql4cpl/bafkreie7jkxonqwgbbcuni4dh54nhodteq24wv4dp6smnvsomdpwpve4we@jpeg)
October 3, 2023 at 8:20 AM
Katalin Karikó on the status economy of academia. She’s the hero we don’t deserve.
Source: josephnoelwalker.com/147-katalin-...
Source: josephnoelwalker.com/147-katalin-...
Its still pretty slow over here....
October 4, 2023 at 3:13 PM
Its still pretty slow over here....
Reposted by David Garfield
Congrats to Karikó and Weissman on the Nobel for mRNA modifications! Their work was not appreciated by the university or reviewers at the time, but has saved millions of lives. A great example of the value of discovery science and reminder to not limit academic research to immediate applications.
October 2, 2023 at 2:55 PM
Congrats to Karikó and Weissman on the Nobel for mRNA modifications! Their work was not appreciated by the university or reviewers at the time, but has saved millions of lives. A great example of the value of discovery science and reminder to not limit academic research to immediate applications.
This is the sort of study that makes it really clear how useful museum can be.
It's fun to get to share our new study in Science tracking nearly 4,000 Galápagos finches using genomics over 30 years! Interested in how genomics can teach us about contemporary evolution? 1/
www.science.org/doi/full/10....
www.science.org/doi/full/10....
September 29, 2023 at 7:07 PM
This is the sort of study that makes it really clear how useful museum can be.
This morning's code is 50% ChatGPT written, I think....
September 26, 2023 at 5:02 PM
This morning's code is 50% ChatGPT written, I think....
Let's all say it again -- distance on a UMAP is not good evidence for cell type similarity and I'm not going to be a happy reviewer when I read that.
September 25, 2023 at 3:57 AM
Let's all say it again -- distance on a UMAP is not good evidence for cell type similarity and I'm not going to be a happy reviewer when I read that.
Reposted by David Garfield
Job alert: We are recruiting a postdoctoral fellow to work on tissue-based single-cell perturbation as part of an @ERC_Research Synergy Project with Wolfgang Huber, Oliver Stegle and Jan Lohmann. #Heidelberg
jobs.dkfz.de/en/jobs/1557...
More information:
erc-decode.eu
Please Repost
jobs.dkfz.de/en/jobs/1557...
More information:
erc-decode.eu
Please Repost
ERC DECODE
erc-decode.eu
September 19, 2023 at 6:50 AM
Job alert: We are recruiting a postdoctoral fellow to work on tissue-based single-cell perturbation as part of an @ERC_Research Synergy Project with Wolfgang Huber, Oliver Stegle and Jan Lohmann. #Heidelberg
jobs.dkfz.de/en/jobs/1557...
More information:
erc-decode.eu
Please Repost
jobs.dkfz.de/en/jobs/1557...
More information:
erc-decode.eu
Please Repost
Reposted by David Garfield
Please spread the word! UNC biostatistics and UNC Genetics are recruiting a tenure-track assistant professor to engage in statistical genetics/genomics methodological and collaborative research
Apply here: unc.peopleadmin.com/postings/265...
Details below
Apply here: unc.peopleadmin.com/postings/265...
Details below
September 18, 2023 at 7:05 PM
Please spread the word! UNC biostatistics and UNC Genetics are recruiting a tenure-track assistant professor to engage in statistical genetics/genomics methodological and collaborative research
Apply here: unc.peopleadmin.com/postings/265...
Details below
Apply here: unc.peopleadmin.com/postings/265...
Details below
So...I'm here now. Where all my science peeps at?
September 9, 2023 at 1:07 AM
So...I'm here now. Where all my science peeps at?