Adriano Bolondi
@adrianobolondi.bsky.social
Researcher @crg.eu, previous MeissnerLab @molgen.mpg.de. Interested in how cells and genes make embryos. #EMBO & #MSCA fellow
Reposted by Adriano Bolondi
"His secret weapons were an unquenchable curiosity and continuing hands-on experimentation at the bench with his beautiful frog embryos and oocytes".
A thoughtful tribute to the life of Sir John Gurdon by Edward M. De Robertis that we really recommend everyone to read.
doi.org/10.1016/j.cd...
A thoughtful tribute to the life of Sir John Gurdon by Edward M. De Robertis that we really recommend everyone to read.
doi.org/10.1016/j.cd...
November 7, 2025 at 9:12 PM
"His secret weapons were an unquenchable curiosity and continuing hands-on experimentation at the bench with his beautiful frog embryos and oocytes".
A thoughtful tribute to the life of Sir John Gurdon by Edward M. De Robertis that we really recommend everyone to read.
doi.org/10.1016/j.cd...
A thoughtful tribute to the life of Sir John Gurdon by Edward M. De Robertis that we really recommend everyone to read.
doi.org/10.1016/j.cd...
Reposted by Adriano Bolondi
@campaslab.bsky.social @jesseveenvliet.bsky.social labs use #gastruloids to explore axial extension in mammalian embryos
www.biorxiv.org/content/10.1...
They find novel mechanisms involving and interplay of proliferation and mechanical constraining.
#NotInTheGenes #CellsRUs
www.biorxiv.org/content/10.1...
They find novel mechanisms involving and interplay of proliferation and mechanical constraining.
#NotInTheGenes #CellsRUs
November 6, 2025 at 6:40 AM
@campaslab.bsky.social @jesseveenvliet.bsky.social labs use #gastruloids to explore axial extension in mammalian embryos
www.biorxiv.org/content/10.1...
They find novel mechanisms involving and interplay of proliferation and mechanical constraining.
#NotInTheGenes #CellsRUs
www.biorxiv.org/content/10.1...
They find novel mechanisms involving and interplay of proliferation and mechanical constraining.
#NotInTheGenes #CellsRUs
Reposted by Adriano Bolondi
Really excited to present the results of a fantastic collaboration with Jesse Veenvliet @jesseveenvliet.bsky.social @mpi-cbg.de @poldresden.bsky.social 🤩
We find a unique mechanism for body axis elongation in mammals, different from other vertebrate species
➡️ www.biorxiv.org/content/10.1...
We find a unique mechanism for body axis elongation in mammals, different from other vertebrate species
➡️ www.biorxiv.org/content/10.1...
October 28, 2025 at 8:25 AM
Really excited to present the results of a fantastic collaboration with Jesse Veenvliet @jesseveenvliet.bsky.social @mpi-cbg.de @poldresden.bsky.social 🤩
We find a unique mechanism for body axis elongation in mammals, different from other vertebrate species
➡️ www.biorxiv.org/content/10.1...
We find a unique mechanism for body axis elongation in mammals, different from other vertebrate species
➡️ www.biorxiv.org/content/10.1...
Reposted by Adriano Bolondi
Oh wow - pre-made templates :) - EB
I am happy to present our latest research at the ISSCR 2026 Annual Meeting, taking place in Montréal, Canada on 8-11 July 2026. #ISSCR2026 invt.io/1bxb7uh48oo @isscr.org
I am happy to present our latest research at the ISSCR 2026 Annual Meeting, taking place in Montréal, Canada on 8-11 July 2026. #ISSCR2026 invt.io/1bxb7uh48oo @isscr.org
I'm speaking at ISSCR 2026 Annual Meeting, join me
Register now
invt.io
October 27, 2025 at 8:15 PM
Oh wow - pre-made templates :) - EB
I am happy to present our latest research at the ISSCR 2026 Annual Meeting, taking place in Montréal, Canada on 8-11 July 2026. #ISSCR2026 invt.io/1bxb7uh48oo @isscr.org
I am happy to present our latest research at the ISSCR 2026 Annual Meeting, taking place in Montréal, Canada on 8-11 July 2026. #ISSCR2026 invt.io/1bxb7uh48oo @isscr.org
Reposted by Adriano Bolondi
Wouldn’t it be cool to leverage the throughput of single-cell data to study splicing regulation even when we lack exon resolution? 😀
Here’s the peer-reviewed version of our paper on how we can measure changes in splicing factor activity in virtually any single-cell dataset: doi.org/10.1093/nar/...
Here’s the peer-reviewed version of our paper on how we can measure changes in splicing factor activity in virtually any single-cell dataset: doi.org/10.1093/nar/...
Using single-cell perturbation screens to decode the regulatory architecture of splicing factor programs
Abstract. Splicing factors shape the isoform pool of most transcribed genes, playing a critical role in cellular physiology. Their dysregulation is a hallm
doi.org
October 25, 2025 at 2:16 PM
Wouldn’t it be cool to leverage the throughput of single-cell data to study splicing regulation even when we lack exon resolution? 😀
Here’s the peer-reviewed version of our paper on how we can measure changes in splicing factor activity in virtually any single-cell dataset: doi.org/10.1093/nar/...
Here’s the peer-reviewed version of our paper on how we can measure changes in splicing factor activity in virtually any single-cell dataset: doi.org/10.1093/nar/...
Reposted by Adriano Bolondi
Fully-funded 4-year PhD Opportunities available at the @crick.ac.uk , including a project in our lab on human #embryomodels Feel free to share with anyone interested, and apply through the online portal before 5th November! 👏
www.crick.ac.uk/careers-stud...
www.crick.ac.uk/careers-stud...
Moris Lab | Investigating human trunk development using stem cell-based embryo models
www.crick.ac.uk
October 6, 2025 at 12:03 PM
Fully-funded 4-year PhD Opportunities available at the @crick.ac.uk , including a project in our lab on human #embryomodels Feel free to share with anyone interested, and apply through the online portal before 5th November! 👏
www.crick.ac.uk/careers-stud...
www.crick.ac.uk/careers-stud...
Reposted by Adriano Bolondi
Two positions available (start Jan/Feb 2026):
- Research Assistant: surl.li/atndnv
- Master Student: surl.li/kgwrni
Deadline: Nov 1st
Please reach out to me (adriano.bolondi@crg.es) if you want to join us in sunny Barcelona!☀️
- Research Assistant: surl.li/atndnv
- Master Student: surl.li/kgwrni
Deadline: Nov 1st
Please reach out to me (adriano.bolondi@crg.es) if you want to join us in sunny Barcelona!☀️
October 2, 2025 at 11:00 AM
Two positions available (start Jan/Feb 2026):
- Research Assistant: surl.li/atndnv
- Master Student: surl.li/kgwrni
Deadline: Nov 1st
Please reach out to me (adriano.bolondi@crg.es) if you want to join us in sunny Barcelona!☀️
- Research Assistant: surl.li/atndnv
- Master Student: surl.li/kgwrni
Deadline: Nov 1st
Please reach out to me (adriano.bolondi@crg.es) if you want to join us in sunny Barcelona!☀️
Reposted by Adriano Bolondi
🚨JOB ALERT🚨
FRIENDS PLEASE SPREAD and RT
We are building a small expert team within the @bokelab.bsky.social at @crg.eu @prbb.org to investigate fundamental questions in oocyte cell biology, focusing on how proteostasis regulation influences dormancy and fertility.
See below 2 calls👇
FRIENDS PLEASE SPREAD and RT
We are building a small expert team within the @bokelab.bsky.social at @crg.eu @prbb.org to investigate fundamental questions in oocyte cell biology, focusing on how proteostasis regulation influences dormancy and fertility.
See below 2 calls👇
October 2, 2025 at 11:00 AM
🚨JOB ALERT🚨
FRIENDS PLEASE SPREAD and RT
We are building a small expert team within the @bokelab.bsky.social at @crg.eu @prbb.org to investigate fundamental questions in oocyte cell biology, focusing on how proteostasis regulation influences dormancy and fertility.
See below 2 calls👇
FRIENDS PLEASE SPREAD and RT
We are building a small expert team within the @bokelab.bsky.social at @crg.eu @prbb.org to investigate fundamental questions in oocyte cell biology, focusing on how proteostasis regulation influences dormancy and fertility.
See below 2 calls👇
Reposted by Adriano Bolondi
yo scientists awesome opportunity! ⬇️🔥
🚨JOB ALERT🚨
FRIENDS PLEASE SPREAD and RT
We are building a small expert team within the @bokelab.bsky.social at @crg.eu @prbb.org to investigate fundamental questions in oocyte cell biology, focusing on how proteostasis regulation influences dormancy and fertility.
See below 2 calls👇
FRIENDS PLEASE SPREAD and RT
We are building a small expert team within the @bokelab.bsky.social at @crg.eu @prbb.org to investigate fundamental questions in oocyte cell biology, focusing on how proteostasis regulation influences dormancy and fertility.
See below 2 calls👇
October 2, 2025 at 11:39 AM
yo scientists awesome opportunity! ⬇️🔥
Reposted by Adriano Bolondi
I think everybody knows but Adri is awesome!
🚨JOB ALERT🚨
FRIENDS PLEASE SPREAD and RT
We are building a small expert team within the @bokelab.bsky.social at @crg.eu @prbb.org to investigate fundamental questions in oocyte cell biology, focusing on how proteostasis regulation influences dormancy and fertility.
See below 2 calls👇
FRIENDS PLEASE SPREAD and RT
We are building a small expert team within the @bokelab.bsky.social at @crg.eu @prbb.org to investigate fundamental questions in oocyte cell biology, focusing on how proteostasis regulation influences dormancy and fertility.
See below 2 calls👇
October 2, 2025 at 12:34 PM
I think everybody knows but Adri is awesome!
🚨JOB ALERT🚨
FRIENDS PLEASE SPREAD and RT
We are building a small expert team within the @bokelab.bsky.social at @crg.eu @prbb.org to investigate fundamental questions in oocyte cell biology, focusing on how proteostasis regulation influences dormancy and fertility.
See below 2 calls👇
FRIENDS PLEASE SPREAD and RT
We are building a small expert team within the @bokelab.bsky.social at @crg.eu @prbb.org to investigate fundamental questions in oocyte cell biology, focusing on how proteostasis regulation influences dormancy and fertility.
See below 2 calls👇
October 2, 2025 at 11:00 AM
🚨JOB ALERT🚨
FRIENDS PLEASE SPREAD and RT
We are building a small expert team within the @bokelab.bsky.social at @crg.eu @prbb.org to investigate fundamental questions in oocyte cell biology, focusing on how proteostasis regulation influences dormancy and fertility.
See below 2 calls👇
FRIENDS PLEASE SPREAD and RT
We are building a small expert team within the @bokelab.bsky.social at @crg.eu @prbb.org to investigate fundamental questions in oocyte cell biology, focusing on how proteostasis regulation influences dormancy and fertility.
See below 2 calls👇
Reposted by Adriano Bolondi
Stay Connected with VGZT Season 7 🌍
From Oct 2025–July 2026, join our online seminar series featuring cutting-edge developmental biology across diverse model organisms. Hear from senior PhD students, postdocs, and PIs as they share their latest discoveries with a global audience.
From Oct 2025–July 2026, join our online seminar series featuring cutting-edge developmental biology across diverse model organisms. Hear from senior PhD students, postdocs, and PIs as they share their latest discoveries with a global audience.
September 25, 2025 at 8:59 AM
Stay Connected with VGZT Season 7 🌍
From Oct 2025–July 2026, join our online seminar series featuring cutting-edge developmental biology across diverse model organisms. Hear from senior PhD students, postdocs, and PIs as they share their latest discoveries with a global audience.
From Oct 2025–July 2026, join our online seminar series featuring cutting-edge developmental biology across diverse model organisms. Hear from senior PhD students, postdocs, and PIs as they share their latest discoveries with a global audience.
Reposted by Adriano Bolondi
THANK YOU for many years of friendship, support and for sharing your great Science
La Pedrera #Barcelona
#NotInTheGenes #CellsRUs #Cambridge
La Pedrera #Barcelona
#NotInTheGenes #CellsRUs #Cambridge
September 22, 2025 at 9:01 PM
THANK YOU for many years of friendship, support and for sharing your great Science
La Pedrera #Barcelona
#NotInTheGenes #CellsRUs #Cambridge
La Pedrera #Barcelona
#NotInTheGenes #CellsRUs #Cambridge
Reposted by Adriano Bolondi
Last days to apply! Cool project, cool cities! :-)
(Please repost! 🙏)
(Please repost! 🙏)
🚨🚨🚨
Please RT!
We're looking for a postdoc to join an exciting joint project between our lab @upf.edu & @crg.eu (Barcelona) and the Sander lab @mdc-berlin.bsky.social (Berlin) investigating how alternative splicing and microexons influences the maturation of pancreatic islets.
Deadline: 30/09/25👇
Please RT!
We're looking for a postdoc to join an exciting joint project between our lab @upf.edu & @crg.eu (Barcelona) and the Sander lab @mdc-berlin.bsky.social (Berlin) investigating how alternative splicing and microexons influences the maturation of pancreatic islets.
Deadline: 30/09/25👇
www.upf.edu
September 22, 2025 at 7:04 AM
Last days to apply! Cool project, cool cities! :-)
(Please repost! 🙏)
(Please repost! 🙏)
Reposted by Adriano Bolondi
With the group that came together @upf.edu in #Barcelona, celebrating 5 years of exploring, dreaming and discovering. Grateful #NotInTheGenes #CellsRUs
September 22, 2025 at 2:40 PM
With the group that came together @upf.edu in #Barcelona, celebrating 5 years of exploring, dreaming and discovering. Grateful #NotInTheGenes #CellsRUs
Reposted by Adriano Bolondi
Excited to post my first #JobOffer! I am looking for a research technician to help me build new projects from the grounds up at @cabd-upo-csic.bsky.social
We will use medaka to study how organs can be reprogrammed!
Details on how to apply below 👇
#JobOffer #ScienceJobs #EvoDevo #GeneRegulation
We will use medaka to study how organs can be reprogrammed!
Details on how to apply below 👇
#JobOffer #ScienceJobs #EvoDevo #GeneRegulation
September 19, 2025 at 8:53 AM
Excited to post my first #JobOffer! I am looking for a research technician to help me build new projects from the grounds up at @cabd-upo-csic.bsky.social
We will use medaka to study how organs can be reprogrammed!
Details on how to apply below 👇
#JobOffer #ScienceJobs #EvoDevo #GeneRegulation
We will use medaka to study how organs can be reprogrammed!
Details on how to apply below 👇
#JobOffer #ScienceJobs #EvoDevo #GeneRegulation
Reposted by Adriano Bolondi
Ever wondered how to get a gastruloid to grow a head?
The Bulut-Karslioğlu lab figured out that by growing different stem cell aggregates in high and low oxygen and later assembling them, you can get gastruloids with a fully formed neural tube. Check out our "In preprints": doi.org/10.1242/dev....
The Bulut-Karslioğlu lab figured out that by growing different stem cell aggregates in high and low oxygen and later assembling them, you can get gastruloids with a fully formed neural tube. Check out our "In preprints": doi.org/10.1242/dev....
In preprints: gastruloids get (a)head
A major breakthrough in the field of mammalian embryology is the development of stem-cell based embryo models. Derived from pluripotent stem cells, such as embryonic stem cells or induced pluripotent ...
doi.org
September 16, 2025 at 8:31 AM
Ever wondered how to get a gastruloid to grow a head?
The Bulut-Karslioğlu lab figured out that by growing different stem cell aggregates in high and low oxygen and later assembling them, you can get gastruloids with a fully formed neural tube. Check out our "In preprints": doi.org/10.1242/dev....
The Bulut-Karslioğlu lab figured out that by growing different stem cell aggregates in high and low oxygen and later assembling them, you can get gastruloids with a fully formed neural tube. Check out our "In preprints": doi.org/10.1242/dev....
Reposted by Adriano Bolondi
🚀 Looking for a Bioinformatician / Data Scientist to join our crew and explore regeneration through single-cell genomics & evolutionary biology! @mpi-bio-fml.bsky.social
📩 Questions? Contact us ✉️
🔗 Apply here: www.mpg.de/25243280/bio...
📩 Questions? Contact us ✉️
🔗 Apply here: www.mpg.de/25243280/bio...
Bioinformatician / Data Scientist (m/f/d)
Bioinformatician / Data scientist position in the Aztekin Lab focusing on Structural Regeneration and support the working group together with the other members
www.mpg.de
September 15, 2025 at 6:58 AM
🚀 Looking for a Bioinformatician / Data Scientist to join our crew and explore regeneration through single-cell genomics & evolutionary biology! @mpi-bio-fml.bsky.social
📩 Questions? Contact us ✉️
🔗 Apply here: www.mpg.de/25243280/bio...
📩 Questions? Contact us ✉️
🔗 Apply here: www.mpg.de/25243280/bio...
Reposted by Adriano Bolondi
🚨 Job Alert: we seek a Lab Manager for @juliabatki.bsky.social's new group (start Mar 2026), which will study cell fate regulation during organ development. Join the Batki's group to drive experiments & lab operations! Apply at: www.fmi.ch/education-ca...
September 2, 2025 at 9:03 AM
🚨 Job Alert: we seek a Lab Manager for @juliabatki.bsky.social's new group (start Mar 2026), which will study cell fate regulation during organ development. Join the Batki's group to drive experiments & lab operations! Apply at: www.fmi.ch/education-ca...
Reposted by Adriano Bolondi
I am excited to announce that we are looking for a Lab Manager @fmiscience.bsky.social in Basel. If you want to be part of a growing team investigating development and tissue formation, and are enthusiastic about helping set up a new lab, please check out the role:
www.fmi.ch/education-ca...
www.fmi.ch/education-ca...
September 14, 2025 at 11:46 AM
I am excited to announce that we are looking for a Lab Manager @fmiscience.bsky.social in Basel. If you want to be part of a growing team investigating development and tissue formation, and are enthusiastic about helping set up a new lab, please check out the role:
www.fmi.ch/education-ca...
www.fmi.ch/education-ca...
Reposted by Adriano Bolondi
🧬 Els oòcits humans “s’apaguen” per protegir-se
➡️Un estudi del #CRGenomica revela que els òvuls humans redueixen l’activitat dels sistemes de neteja quan maduren.
Aquesta aturada parcial podria ser la clau per mantenir-se vius i sans.
ℹ️T'ho expliquem:
➡️Un estudi del #CRGenomica revela que els òvuls humans redueixen l’activitat dels sistemes de neteja quan maduren.
Aquesta aturada parcial podria ser la clau per mantenir-se vius i sans.
ℹ️T'ho expliquem:
Els oòcits humans s'apaguen per protegir-se - El·lipse
Aquesta imatge, de Gabriele Zaffagnini del Centre de Regulació Genòmica (CRG), mostra un oòcit humà fixat i immunotenyit. Les mitocondries es mostren en taronja i el citoesquelet d’actina es mostra en verd. L’ADN es mostra en blau clar. La imatge és part d’un estudi recent realitzat pel laboratori d’Elvan Böke que va mostrar que els […]
tuit.cat
September 15, 2025 at 7:39 AM
🧬 Els oòcits humans “s’apaguen” per protegir-se
➡️Un estudi del #CRGenomica revela que els òvuls humans redueixen l’activitat dels sistemes de neteja quan maduren.
Aquesta aturada parcial podria ser la clau per mantenir-se vius i sans.
ℹ️T'ho expliquem:
➡️Un estudi del #CRGenomica revela que els òvuls humans redueixen l’activitat dels sistemes de neteja quan maduren.
Aquesta aturada parcial podria ser la clau per mantenir-se vius i sans.
ℹ️T'ho expliquem:
Reposted by Adriano Bolondi
📣 New preprint! We present SpinePy, a modular framework that enables automated 3D spatiotemporal quantification of #gastruloids & other multicellular in vitro systems. Spearheaded by @cryaaa.bsky.social @mpi-cbg.de. Check out his thread 👇 & the paper:
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
September 12, 2025 at 4:43 PM
📣 New preprint! We present SpinePy, a modular framework that enables automated 3D spatiotemporal quantification of #gastruloids & other multicellular in vitro systems. Spearheaded by @cryaaa.bsky.social @mpi-cbg.de. Check out his thread 👇 & the paper:
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Adriano Bolondi
Understanding how embryos build themselves requires studying developmental trajectories. This is beautiful work from @santoslab.bsky.social!
Researchers have found that early embryonic cells start to specialise via converging developmental paths, rather than following linear trajectories as was previously believed.
www.crick.ac.uk/news/2025-09...
www.crick.ac.uk/news/2025-09...
Converging development: how cell paths unite in the embryo
By tracking the fate of individual embryonic stem cells, researchers have found that endoderm cells – early embryonic cells that give rise to tissues such as the gut and lungs – originate from multipl...
www.crick.ac.uk
September 10, 2025 at 11:04 AM
Understanding how embryos build themselves requires studying developmental trajectories. This is beautiful work from @santoslab.bsky.social!
Reposted by Adriano Bolondi
Have you ever wondered what happens with your microvessels after exposure to high temperature in fever? In this preprint former postdoc (ans soon to be PI) Viola Introini found that high temperatures cleaves glycocalyx , having severe consequences in malaria www.biorxiv.org/cgi/content/...
Febrile temperature enhances Plasmodium falciparum cytoadhesion by disrupting the endothelial glycocalyx
Fever, a universal host defense in infection and inflammation, paradoxically contributes to neurological complications in malaria. While febrile temperatures enhance the expression of parasite virulen...
www.biorxiv.org
September 9, 2025 at 8:02 AM
Have you ever wondered what happens with your microvessels after exposure to high temperature in fever? In this preprint former postdoc (ans soon to be PI) Viola Introini found that high temperatures cleaves glycocalyx , having severe consequences in malaria www.biorxiv.org/cgi/content/...
Reposted by Adriano Bolondi
I am deeply honoured to have been recognized by the European Research Council with a #StartingGrant. @erc.europa.eu
With this support, my team and I will launch #MOVIOLA. Our goal is to understand how human neural progenitors decide their fate during brain development.
With this support, my team and I will launch #MOVIOLA. Our goal is to understand how human neural progenitors decide their fate during brain development.
Two life sciences ERC Starting Grants at EPFL
Milena Schuhmacher and Gioele La Manno at EPFL’s School of Life Sciences have received European Research Council (ERC) Starting Grants. Former EPFL researcher Can Aztekin (now at Max Planck), is also ...
actu.epfl.ch
September 4, 2025 at 2:38 PM
I am deeply honoured to have been recognized by the European Research Council with a #StartingGrant. @erc.europa.eu
With this support, my team and I will launch #MOVIOLA. Our goal is to understand how human neural progenitors decide their fate during brain development.
With this support, my team and I will launch #MOVIOLA. Our goal is to understand how human neural progenitors decide their fate during brain development.