Matthew L. Kraushar
@matthewkraushar.bsky.social
eukaryote, scientist, group leader at the Max Planck Institute for Molecular Genetics in Berlin, here to support ideas and the people who have them
https://www.molgen.mpg.de/kraushar-lab
https://www.molgen.mpg.de/kraushar-lab
Pinned
Young PI Symposium 2026
Visit the post for more.
youngpisymposium2026.com
yo π¦ NEURO SKY π£ the website is live and registration open for the Young PI Symposium 2026 - the day prior to FENS Barcelona! @young-pi-neuro26.bsky.social
navigate challenges, sharpen leadership skills, make a roadmap together for generations of neuroscientists!
youngpisymposium2026.com
navigate challenges, sharpen leadership skills, make a roadmap together for generations of neuroscientists!
youngpisymposium2026.com
congrats Teresa! we are both 4-year-olds! π₯³ cheers to more science ahead π»
February 9, 2026 at 6:46 PM
congrats Teresa! we are both 4-year-olds! π₯³ cheers to more science ahead π»
Reposted by Matthew L. Kraushar
Time for a thread on our Christmas preprint βOrigin and evolution of acrocentric chromosomes in human and great apesβ. I had so much fun with this project and paper. It will be hard to summarize in a thread, but Iβll try www.biorxiv.org/content/10.6... [1/21]
February 2, 2026 at 2:58 PM
Time for a thread on our Christmas preprint βOrigin and evolution of acrocentric chromosomes in human and great apesβ. I had so much fun with this project and paper. It will be hard to summarize in a thread, but Iβll try www.biorxiv.org/content/10.6... [1/21]
i'll see you there Dafni!
join us to build resilience in these times of uncertainty for neuroscience...for (all)science. anyone reading the news in the US and UK lately? stronger π€ together
join us to build resilience in these times of uncertainty for neuroscience...for (all)science. anyone reading the news in the US and UK lately? stronger π€ together
Last year with @ksiudeja.bsky.social @linneweberlab.bsky.social @michaelrera.bsky.social and @nkonst4.bsky.social we brought back the JEDI meeting from its dormancy. A ton of work but very rewarding to see a community forming. A similar attempt is now πhttps://youngpisymposium2026.com/registration/
Registration (NOW OPEN!)
We welcome participants from diverse geographic and neuroscience backgrounds, with diverse leadership and career development experience. Our participants should be motivated to engage, share, and lβ¦
youngpisymposium2026.com
February 2, 2026 at 4:39 PM
i'll see you there Dafni!
join us to build resilience in these times of uncertainty for neuroscience...for (all)science. anyone reading the news in the US and UK lately? stronger π€ together
join us to build resilience in these times of uncertainty for neuroscience...for (all)science. anyone reading the news in the US and UK lately? stronger π€ together
suuuper cool β€οΈβπ₯π€©β€οΈβπ₯ evolution of a "visceral brain"
tempted to step outside of the "cranial brain" for a hot minute...
tempted to step outside of the "cranial brain" for a hot minute...
𧨠Check out this peeps𧨠I am very happy with the outcome of this thought baby! @neurogut.bsky.social @michaelrera.bsky.social and Mael Lemoine (yes, a philosopher) twisted our brains over preparing this conceptual review! We give you the "Enterarchon" Enjoy it!
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
The Enterarchon: An ancient visceral brain
The gastrointestinal (GI) tract is innervated by intrinsic neurites and extrinsic pathways linking it bidirectionally to the central nervous system. Tβ¦
www.sciencedirect.com
February 2, 2026 at 4:36 PM
suuuper cool β€οΈβπ₯π€©β€οΈβπ₯ evolution of a "visceral brain"
tempted to step outside of the "cranial brain" for a hot minute...
tempted to step outside of the "cranial brain" for a hot minute...
Reposted by Matthew L. Kraushar
FoldMason is out now in @science.org. It generates accurate multiple structure alignments for thousands of protein structures in seconds. Great work by Cameron L. M. Gilchrist and @milot.bsky.social.
π www.science.org/doi/10.1126/...
π search.foldseek.com/foldmason
πΎ github.com/steineggerla...
π www.science.org/doi/10.1126/...
π search.foldseek.com/foldmason
πΎ github.com/steineggerla...
Multiple protein structure alignment at scale with FoldMason
Protein structure is conserved beyond sequence, making multiple structural alignment (MSTA) essential for analyzing distantly related proteins. Computational prediction methods have vastly extended ou...
www.science.org
January 30, 2026 at 6:11 AM
FoldMason is out now in @science.org. It generates accurate multiple structure alignments for thousands of protein structures in seconds. Great work by Cameron L. M. Gilchrist and @milot.bsky.social.
π www.science.org/doi/10.1126/...
π search.foldseek.com/foldmason
πΎ github.com/steineggerla...
π www.science.org/doi/10.1126/...
π search.foldseek.com/foldmason
πΎ github.com/steineggerla...
your spaceship to the protein folding universe ππ½ from captain Steinegger and crew π§βπ
FoldMason is out now in @science.org. It generates accurate multiple structure alignments for thousands of protein structures in seconds. Great work by Cameron L. M. Gilchrist and @milot.bsky.social.
π www.science.org/doi/10.1126/...
π search.foldseek.com/foldmason
πΎ github.com/steineggerla...
π www.science.org/doi/10.1126/...
π search.foldseek.com/foldmason
πΎ github.com/steineggerla...
Multiple protein structure alignment at scale with FoldMason
Protein structure is conserved beyond sequence, making multiple structural alignment (MSTA) essential for analyzing distantly related proteins. Computational prediction methods have vastly extended ou...
www.science.org
January 30, 2026 at 8:45 AM
your spaceship to the protein folding universe ππ½ from captain Steinegger and crew π§βπ
Reposted by Matthew L. Kraushar
now online:
academic.oup.com/nar/article/...
academic.oup.com/nar/article/...
Structures of naked mole-rat, tuco-tuco, and guinea pig ribosomesβis rRNA fragmentation linked to translational fidelity?
Abstract. Ribosomes are central to protein synthesis in all organisms. In mammals, the ribosome functional core is highly conserved. Remarkably, two rodent
academic.oup.com
January 29, 2026 at 1:47 PM
now online:
academic.oup.com/nar/article/...
academic.oup.com/nar/article/...
Reposted by Matthew L. Kraushar
We wrote a protocol article detailing induction of dormancy in stem cells, embryos, and blastoids. We hope that it is useful to the community. As usual fun to work with @nicolasrivron.bsky.social, Heidar and Dhanur.
January 26, 2026 at 6:55 PM
We wrote a protocol article detailing induction of dormancy in stem cells, embryos, and blastoids. We hope that it is useful to the community. As usual fun to work with @nicolasrivron.bsky.social, Heidar and Dhanur.
Reposted by Matthew L. Kraushar
yo π¦ NEURO SKY π£ the website is live and registration open for the Young PI Symposium 2026 - the day prior to FENS Barcelona! @young-pi-neuro26.bsky.social
navigate challenges, sharpen leadership skills, make a roadmap together for generations of neuroscientists!
youngpisymposium2026.com
navigate challenges, sharpen leadership skills, make a roadmap together for generations of neuroscientists!
youngpisymposium2026.com
Young PI Symposium 2026
Visit the post for more.
youngpisymposium2026.com
January 15, 2026 at 5:04 PM
yo π¦ NEURO SKY π£ the website is live and registration open for the Young PI Symposium 2026 - the day prior to FENS Barcelona! @young-pi-neuro26.bsky.social
navigate challenges, sharpen leadership skills, make a roadmap together for generations of neuroscientists!
youngpisymposium2026.com
navigate challenges, sharpen leadership skills, make a roadmap together for generations of neuroscientists!
youngpisymposium2026.com
thanks to the labs that joined us!
Alex von Appen @mpi-cbg.de
Mike Robson, Misha Kudryashev @mdc-berlin.bsky.social
Sedona Murphy, Johannes Stein @molgen.mpg.de
Efrat Shema Weizmann/@molgen.mpg.de
Alex von Appen @mpi-cbg.de
Mike Robson, Misha Kudryashev @mdc-berlin.bsky.social
Sedona Murphy, Johannes Stein @molgen.mpg.de
Efrat Shema Weizmann/@molgen.mpg.de
January 23, 2026 at 4:18 PM
thanks to the labs that joined us!
Alex von Appen @mpi-cbg.de
Mike Robson, Misha Kudryashev @mdc-berlin.bsky.social
Sedona Murphy, Johannes Stein @molgen.mpg.de
Efrat Shema Weizmann/@molgen.mpg.de
Alex von Appen @mpi-cbg.de
Mike Robson, Misha Kudryashev @mdc-berlin.bsky.social
Sedona Murphy, Johannes Stein @molgen.mpg.de
Efrat Shema Weizmann/@molgen.mpg.de
Lovely science symposium this week in Berlin, co-organized by my lab at MPI @molgen.mpg.de and Ori Avinoam's lab at the Weizmann
Supported by generous funding from the Heineman & Minerva Foundations, for @maxplanck.de π€ Weizmann collaboration. Science π€ Food π€ Drinks π«Ά Friends
Supported by generous funding from the Heineman & Minerva Foundations, for @maxplanck.de π€ Weizmann collaboration. Science π€ Food π€ Drinks π«Ά Friends
January 23, 2026 at 4:13 PM
Lovely science symposium this week in Berlin, co-organized by my lab at MPI @molgen.mpg.de and Ori Avinoam's lab at the Weizmann
Supported by generous funding from the Heineman & Minerva Foundations, for @maxplanck.de π€ Weizmann collaboration. Science π€ Food π€ Drinks π«Ά Friends
Supported by generous funding from the Heineman & Minerva Foundations, for @maxplanck.de π€ Weizmann collaboration. Science π€ Food π€ Drinks π«Ά Friends
this is exactly in the spirit of our Young PI Symposium 2026!
π€ Resilience for Neuroscience in Times of Uncertainty π€
π register!
youngpisymposium2026.com
π€ Resilience for Neuroscience in Times of Uncertainty π€
π register!
youngpisymposium2026.com
January 17, 2026 at 7:51 PM
this is exactly in the spirit of our Young PI Symposium 2026!
π€ Resilience for Neuroscience in Times of Uncertainty π€
π register!
youngpisymposium2026.com
π€ Resilience for Neuroscience in Times of Uncertainty π€
π register!
youngpisymposium2026.com
Reposted by Matthew L. Kraushar
Coming up!!!! Registration now open!!!!! a forum to meet more peers in the baby PIs neuro world! location is not bad either!!! Go on register!!
π£ Our website is live and registration is NOW OPEN for the Young PI Symposium 2026 - the day prior to FENS Barcelona!
Navigate challenges, sharpen leadership skills, make a roadmap together for generations of neuroscientists!
youngpisymposium2026.com
Check out our program and join us!
Navigate challenges, sharpen leadership skills, make a roadmap together for generations of neuroscientists!
youngpisymposium2026.com
Check out our program and join us!
Young PI Symposium 2026
Visit the post for more.
youngpisymposium2026.com
January 16, 2026 at 5:00 PM
Coming up!!!! Registration now open!!!!! a forum to meet more peers in the baby PIs neuro world! location is not bad either!!! Go on register!!
Reposted by Matthew L. Kraushar
This Saturday at WFMU's Monty Hall: "Sun Ra: Do the Impossible," a kaleidoscopic portrait of the visionary jazz musician, composer, and poet. Hosted by DJ Irwin Chusid. Q&A to follow w/exec producer Bradford Smith and Sun Ra biographer Paul Youngquist. Tix/info:
Sun Ra: Do the Impossible
A kaleidoscopic portrait of the visionary jazz musician, composer, and poet known as Sun Ra.
www.eventbrite.com
January 15, 2026 at 4:15 PM
This Saturday at WFMU's Monty Hall: "Sun Ra: Do the Impossible," a kaleidoscopic portrait of the visionary jazz musician, composer, and poet. Hosted by DJ Irwin Chusid. Q&A to follow w/exec producer Bradford Smith and Sun Ra biographer Paul Youngquist. Tix/info:
anything you've gotten in your career was got by you being a badass genius
π€π§ π€
π€π§ π€
January 15, 2026 at 7:43 PM
anything you've gotten in your career was got by you being a badass genius
π€π§ π€
π€π§ π€
Reposted by Matthew L. Kraushar
New preprint from my lab!!!
We took advantage of the MitoTag mouse line to study what mRNAs associate with mitochondria in axons in vivo, and we were in for a surprise! Other than our favorite Pink1, mainly cytoskeletal mRNAs hitch a ride and pave the way for axon growth. shorturl.at/rYe1U
We took advantage of the MitoTag mouse line to study what mRNAs associate with mitochondria in axons in vivo, and we were in for a surprise! Other than our favorite Pink1, mainly cytoskeletal mRNAs hitch a ride and pave the way for axon growth. shorturl.at/rYe1U
Mitochondrial hitch-hiking of Mapt mRNA maintains Tau levels in axons
Hitch-hiking of transcripts on organelles, including mitochondria, has emerged as a common pathway to transport mRNAs into the axon to enable their local translation. However, the extent of mitochondr...
shorturl.at
January 15, 2026 at 10:17 AM
New preprint from my lab!!!
We took advantage of the MitoTag mouse line to study what mRNAs associate with mitochondria in axons in vivo, and we were in for a surprise! Other than our favorite Pink1, mainly cytoskeletal mRNAs hitch a ride and pave the way for axon growth. shorturl.at/rYe1U
We took advantage of the MitoTag mouse line to study what mRNAs associate with mitochondria in axons in vivo, and we were in for a surprise! Other than our favorite Pink1, mainly cytoskeletal mRNAs hitch a ride and pave the way for axon growth. shorturl.at/rYe1U
yo π¦ NEURO SKY π£ the website is live and registration open for the Young PI Symposium 2026 - the day prior to FENS Barcelona! @young-pi-neuro26.bsky.social
navigate challenges, sharpen leadership skills, make a roadmap together for generations of neuroscientists!
youngpisymposium2026.com
navigate challenges, sharpen leadership skills, make a roadmap together for generations of neuroscientists!
youngpisymposium2026.com
Young PI Symposium 2026
Visit the post for more.
youngpisymposium2026.com
January 15, 2026 at 5:04 PM
yo π¦ NEURO SKY π£ the website is live and registration open for the Young PI Symposium 2026 - the day prior to FENS Barcelona! @young-pi-neuro26.bsky.social
navigate challenges, sharpen leadership skills, make a roadmap together for generations of neuroscientists!
youngpisymposium2026.com
navigate challenges, sharpen leadership skills, make a roadmap together for generations of neuroscientists!
youngpisymposium2026.com
Reposted by Matthew L. Kraushar
We spend way too much time manually analyzing #microtubules π¬
Together with Mario, Justus, Dominik, Felix & Erik we used synthetic data and foundation models to build a fully automated segmentation pipeline.β¨
#microscopy, #imageanalysis & #AI
Check out our preprint:
www.biorxiv.org/content/10.6...
Together with Mario, Justus, Dominik, Felix & Erik we used synthetic data and foundation models to build a fully automated segmentation pipeline.β¨
#microscopy, #imageanalysis & #AI
Check out our preprint:
www.biorxiv.org/content/10.6...
January 14, 2026 at 4:33 PM
We spend way too much time manually analyzing #microtubules π¬
Together with Mario, Justus, Dominik, Felix & Erik we used synthetic data and foundation models to build a fully automated segmentation pipeline.β¨
#microscopy, #imageanalysis & #AI
Check out our preprint:
www.biorxiv.org/content/10.6...
Together with Mario, Justus, Dominik, Felix & Erik we used synthetic data and foundation models to build a fully automated segmentation pipeline.β¨
#microscopy, #imageanalysis & #AI
Check out our preprint:
www.biorxiv.org/content/10.6...
Reposted by Matthew L. Kraushar
π£First preprint of the labπ£ Did that really happen?π
Enteric neurons, aka somatic postmitotic cells, must hold on to their sex identity tight, to deliver a tuned response to signals from the ovary that instruct the animal to engage sex-matched behavioural programmes.
www.biorxiv.org/content/10.6...
Enteric neurons, aka somatic postmitotic cells, must hold on to their sex identity tight, to deliver a tuned response to signals from the ovary that instruct the animal to engage sex-matched behavioural programmes.
www.biorxiv.org/content/10.6...
Genetic sex of enteric neurons enables ovarian relaxin to gate maternal gut plasticity
Animals must align intestinal plasticity and feeding with reproductive state, yet the checkpoint that gates these adaptations is unknown. Here we show that an ovary-to-enteric-neuron axis gates the on...
www.biorxiv.org
January 11, 2026 at 3:32 PM
π£First preprint of the labπ£ Did that really happen?π
Enteric neurons, aka somatic postmitotic cells, must hold on to their sex identity tight, to deliver a tuned response to signals from the ovary that instruct the animal to engage sex-matched behavioural programmes.
www.biorxiv.org/content/10.6...
Enteric neurons, aka somatic postmitotic cells, must hold on to their sex identity tight, to deliver a tuned response to signals from the ovary that instruct the animal to engage sex-matched behavioural programmes.
www.biorxiv.org/content/10.6...
woot woot! congrats Dafni and team π₯β€οΈβπ₯π₯
January 12, 2026 at 6:57 PM
woot woot! congrats Dafni and team π₯β€οΈβπ₯π₯
rock on Nikos & team! π€
January 10, 2026 at 10:14 PM
rock on Nikos & team! π€
Reposted by Matthew L. Kraushar
I am very happy (and a bit scared) to present to you what we have been working on over the last 4 years. This manuscript is exactly what I dreamt of when I started the lab and I could not be happier and prouder of the outcome!
Evolutionary dynamics of temporal transcription factor series in the insect optic lobe https://www.biorxiv.org/content/10.64898/2026.01.08.698497v1
January 10, 2026 at 9:43 AM
I am very happy (and a bit scared) to present to you what we have been working on over the last 4 years. This manuscript is exactly what I dreamt of when I started the lab and I could not be happier and prouder of the outcome!
Reposted by Matthew L. Kraushar
Excited to publish our work on how mutations in the muscle-specific ribosomal protein RPL3L drive severe heart disease. This is Part I of a larger body of work led by Michael - stay tuned for Part II on how specialized ribosomes function in normal physiology www.nature.com/articles/s44...
January 10, 2026 at 4:09 PM
Excited to publish our work on how mutations in the muscle-specific ribosomal protein RPL3L drive severe heart disease. This is Part I of a larger body of work led by Michael - stay tuned for Part II on how specialized ribosomes function in normal physiology www.nature.com/articles/s44...
a 55 ribosome chimera session is what i want from santa this christmas
Just in time for 2026! π Presenting a nascent-centric view on the shape of the ribosomal exit tunnel topology, based on MD-derived occupancy maps for 55 distinct ribosomes. π§Άπ§¬π₯οΈ
π Read the preprint: biorxiv.org/content/10.6...
#StructuralBiology #Ribosome #CryoEM #Evolution #Biophysics
π Read the preprint: biorxiv.org/content/10.6...
#StructuralBiology #Ribosome #CryoEM #Evolution #Biophysics
Evolution of the ribosomal exit tunnel through the eyes of the nascent chain
The ribosomal exit tunnel is a universally conserved feature of the large subunit that directs the nascent polypeptide chain into the cellular environment and is involved in co-translational folding, ...
biorxiv.org
December 31, 2025 at 3:39 PM
a 55 ribosome chimera session is what i want from santa this christmas
Reposted by Matthew L. Kraushar
Are you looking to establish yourself as a scientific group leader? Biotech Research & Innovation Centre (BRIC), University of Copenhagen is recruiting 1-2 junior group leaders to join our research centre in the heart of Copenhagen.
See more at www.bric.ku.dk
Please repost and get in touch
See more at www.bric.ku.dk
Please repost and get in touch
December 28, 2025 at 1:59 PM
Are you looking to establish yourself as a scientific group leader? Biotech Research & Innovation Centre (BRIC), University of Copenhagen is recruiting 1-2 junior group leaders to join our research centre in the heart of Copenhagen.
See more at www.bric.ku.dk
Please repost and get in touch
See more at www.bric.ku.dk
Please repost and get in touch