The Hassan Brain Development Team
@hassanbraindevlab.bsky.social
We study the genetic control and molecular regulation of brain development - and a little bit of function - in fly, mouse and human stem cell models
Reposted by The Hassan Brain Development Team
Today we had the pleasure of hosting Dr. Bassem Hassan @hassanbraindevlab.bsky.social from @institutducerveau.bsky.social at our #SeminarsIN with his talk: “Temporal control of neurogenesis”
A fantastic lecture, thank you! 👏👏
@csic.es @dicv.csic.es @umh.es @borrell-lab.bsky.social
A fantastic lecture, thank you! 👏👏
@csic.es @dicv.csic.es @umh.es @borrell-lab.bsky.social
October 31, 2025 at 7:11 PM
Today we had the pleasure of hosting Dr. Bassem Hassan @hassanbraindevlab.bsky.social from @institutducerveau.bsky.social at our #SeminarsIN with his talk: “Temporal control of neurogenesis”
A fantastic lecture, thank you! 👏👏
@csic.es @dicv.csic.es @umh.es @borrell-lab.bsky.social
A fantastic lecture, thank you! 👏👏
@csic.es @dicv.csic.es @umh.es @borrell-lab.bsky.social
Reposted by The Hassan Brain Development Team
We have the pleasure of welcoming Dr Bassem Hassan @hassanbraindevlab.bsky.social from @institutducerveau.bsky.social tomorrow at #SeminarsIN 🙌
He is a world leader in the study of genetic regulation of brain development.
Don’t miss it!
@borrell-lab.bsky.social @csic.es @dicv.csic.es @umh.es
He is a world leader in the study of genetic regulation of brain development.
Don’t miss it!
@borrell-lab.bsky.social @csic.es @dicv.csic.es @umh.es
October 30, 2025 at 1:33 PM
We have the pleasure of welcoming Dr Bassem Hassan @hassanbraindevlab.bsky.social from @institutducerveau.bsky.social tomorrow at #SeminarsIN 🙌
He is a world leader in the study of genetic regulation of brain development.
Don’t miss it!
@borrell-lab.bsky.social @csic.es @dicv.csic.es @umh.es
He is a world leader in the study of genetic regulation of brain development.
Don’t miss it!
@borrell-lab.bsky.social @csic.es @dicv.csic.es @umh.es
A wonderful collaboration with @alexbaffet.bsky.social @boyanbonev.bsky.social and @neurogenesis-i3s.bsky.social labs
www.biorxiv.org/content/10.1...
Our latest: Julien Pigeon and colleagues discover a mechanism linking post-translational modification of transcription factors to remodeling the chromatin landscape to regulate human cortical neurogenesis
Our latest: Julien Pigeon and colleagues discover a mechanism linking post-translational modification of transcription factors to remodeling the chromatin landscape to regulate human cortical neurogenesis
Post-translational Tuning of Human Cortical Progenitor Neuronal Output
The striking expansion of the human neocortex is driven by the ability of radial glial cells (RGCs) to prolong neurogenesis without exhausting their progenitor pool, thereby producing more neurons, pa...
www.biorxiv.org
October 28, 2025 at 7:18 AM
A wonderful collaboration with @alexbaffet.bsky.social @boyanbonev.bsky.social and @neurogenesis-i3s.bsky.social labs
www.biorxiv.org/content/10.1...
Our latest: Julien Pigeon and colleagues discover a mechanism linking post-translational modification of transcription factors to remodeling the chromatin landscape to regulate human cortical neurogenesis
Our latest: Julien Pigeon and colleagues discover a mechanism linking post-translational modification of transcription factors to remodeling the chromatin landscape to regulate human cortical neurogenesis
Post-translational Tuning of Human Cortical Progenitor Neuronal Output
The striking expansion of the human neocortex is driven by the ability of radial glial cells (RGCs) to prolong neurogenesis without exhausting their progenitor pool, thereby producing more neurons, pa...
www.biorxiv.org
October 28, 2025 at 7:10 AM
www.biorxiv.org/content/10.1...
Our latest: Julien Pigeon and colleagues discover a mechanism linking post-translational modification of transcription factors to remodeling the chromatin landscape to regulate human cortical neurogenesis
Our latest: Julien Pigeon and colleagues discover a mechanism linking post-translational modification of transcription factors to remodeling the chromatin landscape to regulate human cortical neurogenesis
Latest from the lab: the immensely talented Johnny Bou Rouphael and Laila El Khattabi in the team report the discovery and functional analysis defective splicing in a human developmental disorder. www.linkedin.com/posts/bassem...
Heterozygous pathogenic variants in the splicing factor SF1 lead to a large spectrum of neurodevelopmental disorders | Bassem Hassan
Latest from the lab: the immensely talented Johnny Bou Rouphael and Laila El Khattabi in the team report the discovery and functional analysis defective splicing in a human developmental disorder.
www.linkedin.com
September 22, 2025 at 5:54 PM
Latest from the lab: the immensely talented Johnny Bou Rouphael and Laila El Khattabi in the team report the discovery and functional analysis defective splicing in a human developmental disorder. www.linkedin.com/posts/bassem...
For those who understand Arabic 😊
A podcast about @bassemh.bsky.social work and career. Thank you Haifa Alhadyian, PhD for this amazing initiative.
www.linkedin.com/posts/activi...
A podcast about @bassemh.bsky.social work and career. Thank you Haifa Alhadyian, PhD for this amazing initiative.
www.linkedin.com/posts/activi...
الحلقة الأولى من بودكاست "مقابلات مع علماء عرب حول العالم" متاحه للإستماع الآن 🎙️ 🧠 🔬 ..
ضيفي للحلقة الأولى هو الدكتور باسم حسن (Bassem Hassan)، قائد فريق في معهد باريس للدماغ في فرنسا في ...
الحلقة الأولى من بودكاست "مقابلات مع علماء عرب حول العالم" متاحه للإستماع الآن 🎙️ 🧠 🔬 ..
ضيفي للحلقة الأولى هو الدكتور باسم حسن (Bassem Hassan)، قائد فريق في معهد باريس للدماغ في فرنسا في تخصص علم ا...
www.linkedin.com
September 22, 2025 at 11:13 AM
For those who understand Arabic 😊
A podcast about @bassemh.bsky.social work and career. Thank you Haifa Alhadyian, PhD for this amazing initiative.
www.linkedin.com/posts/activi...
A podcast about @bassemh.bsky.social work and career. Thank you Haifa Alhadyian, PhD for this amazing initiative.
www.linkedin.com/posts/activi...
Reposted by The Hassan Brain Development Team
Excited to share our latest paper in Nature Communications! We uncovered a dev-time transcriptional program (via Mirana → Pink1) that shapes mitochondria & circuit wiring.
Disrupt it early, and neurons miswire — even if the gene recovers later!
Disrupt it early, and neurons miswire — even if the gene recovers later!
Latest from the lab, the beautiful work of Iryna Mohylyak and colleagues describing a temporal developmental transcriptional program for mitochondrial quality control and synaptic connectivity, with @jdejuan-sanz.bsky.social, Olga Corti and @steinaerts.bsky.social
labs
www.nature.com/articles/s41...
labs
www.nature.com/articles/s41...
Temporal transcriptional regulation of mitochondrial morphology primes activity-dependent circuit connectivity - Nature Communications
This study investigates the developmental transcriptional regulation of mitochondrial quality control. Authors identify the Drosophila factor Mirana, homologous to mammalian TZAP, as a key temporal re...
www.nature.com
September 16, 2025 at 3:17 PM
Excited to share our latest paper in Nature Communications! We uncovered a dev-time transcriptional program (via Mirana → Pink1) that shapes mitochondria & circuit wiring.
Disrupt it early, and neurons miswire — even if the gene recovers later!
Disrupt it early, and neurons miswire — even if the gene recovers later!
Registration is now open for 2026 GRC on Neural Development
@neuraldevgrc.bsky.social
Register early because places go fast!
@neuraldevgrc.bsky.social
Register early because places go fast!
September 11, 2025 at 2:21 PM
Registration is now open for 2026 GRC on Neural Development
@neuraldevgrc.bsky.social
Register early because places go fast!
@neuraldevgrc.bsky.social
Register early because places go fast!
Latest from the lab, the beautiful work of Iryna Mohylyak and colleagues describing a temporal developmental transcriptional program for mitochondrial quality control and synaptic connectivity, with @jdejuan-sanz.bsky.social, Olga Corti and @steinaerts.bsky.social
labs
www.nature.com/articles/s41...
labs
www.nature.com/articles/s41...
Temporal transcriptional regulation of mitochondrial morphology primes activity-dependent circuit connectivity - Nature Communications
This study investigates the developmental transcriptional regulation of mitochondrial quality control. Authors identify the Drosophila factor Mirana, homologous to mammalian TZAP, as a key temporal re...
www.nature.com
September 1, 2025 at 8:50 PM
Latest from the lab, the beautiful work of Iryna Mohylyak and colleagues describing a temporal developmental transcriptional program for mitochondrial quality control and synaptic connectivity, with @jdejuan-sanz.bsky.social, Olga Corti and @steinaerts.bsky.social
labs
www.nature.com/articles/s41...
labs
www.nature.com/articles/s41...
Reposted by The Hassan Brain Development Team
👋🏻 Bluesky!
Bassem Hassan @bassemh.bsky.social, Corey Harwell & yours truly are co-chairs for 2026 Neural Development #GRC August 2-7, 2026 in Newport, RI 🇺🇸 - if you are interested in updates on the conference & to hear about our 🤩 line-up of speakers...follow @neuraldevgrc.bsky.social!
🧠🪰🐭🐙🐸🦎🧒🏻🧫🧪🧠
🧠🪰🐭🐙🐸🦎🧒🏻🧫🧪🧠
July 14, 2025 at 8:29 PM
👋🏻 Bluesky!
Reposted by The Hassan Brain Development Team
Bassem Hassan @bassemh.bsky.social, Corey Harwell & yours truly are co-chairs for 2026 Neural Development #GRC August 2-7, 2026 in Newport, RI 🇺🇸 - if you are interested in updates on the conference & to hear about our 🤩 line-up of speakers...follow @neuraldevgrc.bsky.social!
🧠🪰🐭🐙🐸🦎🧒🏻🧫🧪🧠
🧠🪰🐭🐙🐸🦎🧒🏻🧫🧪🧠
July 14, 2025 at 8:28 PM
Bassem Hassan @bassemh.bsky.social, Corey Harwell & yours truly are co-chairs for 2026 Neural Development #GRC August 2-7, 2026 in Newport, RI 🇺🇸 - if you are interested in updates on the conference & to hear about our 🤩 line-up of speakers...follow @neuraldevgrc.bsky.social!
🧠🪰🐭🐙🐸🦎🧒🏻🧫🧪🧠
🧠🪰🐭🐙🐸🦎🧒🏻🧫🧪🧠
Congrats to the fantastic @maheandria.bsky.social on this well deserved recognition from French Academy of Science
It is a Great Honour to receive the 'Les Grandes Avancées en Biologie' award 🏅 from the @academiesciences.bsky.social and to share our work during this fabulous day celebrating Science. Thank you!
@hassanbraindevlab.bsky.social @institutducerveau.bsky.social @frm-officiel.bsky.social
@hassanbraindevlab.bsky.social @institutducerveau.bsky.social @frm-officiel.bsky.social
June 19, 2025 at 2:32 PM
Congrats to the fantastic @maheandria.bsky.social on this well deserved recognition from French Academy of Science
Reposted by The Hassan Brain Development Team
This journey began in Berlin with @bassemh.bsky.social and Robin Hiesinger, and continued at @institutducerveau.bsky.social in @hassanbraindevlab.bsky.social , with the generous support of @frm-officiel.bsky.social . Grateful to the von Kleist & Stoeckli Labs and all co-authors!
May 7, 2025 at 10:51 AM
This journey began in Berlin with @bassemh.bsky.social and Robin Hiesinger, and continued at @institutducerveau.bsky.social in @hassanbraindevlab.bsky.social , with the generous support of @frm-officiel.bsky.social . Grateful to the von Kleist & Stoeckli Labs and all co-authors!
Reposted by The Hassan Brain Development Team
A temporal sequence of genetically encoded stochastic mechanisms explains variation in stereotyped neuronal circuits in Drosophila 🧪🧠
@bassemh.bsky.social @maheandria.bsky.social @hassanbraindevlab.bsky.social @institutducerveau.bsky.social
www.nature.com/articles/s41...
@bassemh.bsky.social @maheandria.bsky.social @hassanbraindevlab.bsky.social @institutducerveau.bsky.social
www.nature.com/articles/s41...
Sequential and independent probabilistic events regulate differential axon targeting during development in Drosophila melanogaster - Nature Neuroscience
The developmental origin of behavioral individuality is unclear. The authors show that a temporal sequence of genetically encoded stochastic mechanisms explains variation in stereotyped neuronal circu...
www.nature.com
May 7, 2025 at 11:15 AM
A temporal sequence of genetically encoded stochastic mechanisms explains variation in stereotyped neuronal circuits in Drosophila 🧪🧠
@bassemh.bsky.social @maheandria.bsky.social @hassanbraindevlab.bsky.social @institutducerveau.bsky.social
www.nature.com/articles/s41...
@bassemh.bsky.social @maheandria.bsky.social @hassanbraindevlab.bsky.social @institutducerveau.bsky.social
www.nature.com/articles/s41...
New from the lab: @maheandria.bsky.social and colleagues in collaboration with the Hiesinger, Stoeckli and von Kleist labs dissect the sequential emergence of axonal targeting during development in today's issue of Nature Neuroscience:
rdcu.be/ek010
rdcu.be/ek010
Sequential and independent probabilistic events regulate differential axon targeting during development in Drosophila melanogaster
Nature Neuroscience - The developmental origin of behavioral individuality is unclear. The authors show that a temporal sequence of genetically encoded stochastic mechanisms explains variation in...
rdcu.be
May 7, 2025 at 11:31 AM
New from the lab: @maheandria.bsky.social and colleagues in collaboration with the Hiesinger, Stoeckli and von Kleist labs dissect the sequential emergence of axonal targeting during development in today's issue of Nature Neuroscience:
rdcu.be/ek010
rdcu.be/ek010
Reposted by The Hassan Brain Development Team
Hot off the press:
The excellent Maheva Andriatsilavo and colleagues show how a temporal sequence of stochastic molecular mechanisms allow the emergence of stereotyped individualised neuronal circuits. Just published in Nature Neuroscience:
rdcu.be/ek010
The excellent Maheva Andriatsilavo and colleagues show how a temporal sequence of stochastic molecular mechanisms allow the emergence of stereotyped individualised neuronal circuits. Just published in Nature Neuroscience:
rdcu.be/ek010
Sequential and independent probabilistic events regulate differential axon targeting during development in Drosophila melanogaster
Nature Neuroscience - The developmental origin of behavioral individuality is unclear. The authors show that a temporal sequence of genetically encoded stochastic mechanisms explains variation in...
rdcu.be
May 7, 2025 at 11:26 AM
Hot off the press:
The excellent Maheva Andriatsilavo and colleagues show how a temporal sequence of stochastic molecular mechanisms allow the emergence of stereotyped individualised neuronal circuits. Just published in Nature Neuroscience:
rdcu.be/ek010
The excellent Maheva Andriatsilavo and colleagues show how a temporal sequence of stochastic molecular mechanisms allow the emergence of stereotyped individualised neuronal circuits. Just published in Nature Neuroscience:
rdcu.be/ek010
👇🏽
@maheandria.bsky.social and I challenge the notion of a static and deterministic definition of a (neural) cell type and argue for its replacement by a multi parametric probabilistic definition in this perspective
sciencedirect.com/science/arti...
sciencedirect.com/science/arti...
Toward a probabilistic definition of neural cell types
A classical view of cell type relies on a definite set of stable properties that are critical for brain functions. Single-cell technologies led to an …
sciencedirect.com
May 6, 2025 at 12:53 PM
👇🏽
Anna CHRZANOWSKA, PhD, postdoc in The Hassan Brain Development Team
@hassanbraindevlab.bsky.social
is organizing a trainee-led symposium @institutducerveau.bsky.social June 2-4
Spread the word!
nenckiopenlab.org/decoding/
@hassanbraindevlab.bsky.social
is organizing a trainee-led symposium @institutducerveau.bsky.social June 2-4
Spread the word!
nenckiopenlab.org/decoding/
Nencki Open Lab
Decoding the brain: from methods to meaning Paris Brain Institute, June 2-4th 2025 Applying machine learning and other models to decode behavioral parameters from neural activity is now a standard …
nenckiopenlab.org
April 30, 2025 at 3:28 PM
Anna CHRZANOWSKA, PhD, postdoc in The Hassan Brain Development Team
@hassanbraindevlab.bsky.social
is organizing a trainee-led symposium @institutducerveau.bsky.social June 2-4
Spread the word!
nenckiopenlab.org/decoding/
@hassanbraindevlab.bsky.social
is organizing a trainee-led symposium @institutducerveau.bsky.social June 2-4
Spread the word!
nenckiopenlab.org/decoding/
Reposted by The Hassan Brain Development Team
Can't miss opportunity for anyone interested in developmental timing!! See you in Paris⏳️
Join us in Paris 6-9 May 2025 for the #EvoDevoTempo conference (2nd edition) with a fantastic line up of speakers confirmed!!
Organized by @mdiazcuadros.bsky.social
@vanderhaeghenp2.bsky.social
@bassemh.bsky.social and me.
Please RT to spread the word
meetings.embo.org/event/25-dev...
Organized by @mdiazcuadros.bsky.social
@vanderhaeghenp2.bsky.social
@bassemh.bsky.social and me.
Please RT to spread the word
meetings.embo.org/event/25-dev...
Developmental timing across species: From mechanisms to evolutionary insights
Like choreography, development consists of a highly ordered suite of steps and transitions. Modifying developmental tempo can affect final size and composition of tissues, as well as their plasticity…
meetings.embo.org
December 20, 2024 at 5:02 PM
Can't miss opportunity for anyone interested in developmental timing!! See you in Paris⏳️
Reposted by The Hassan Brain Development Team
Join us in Paris 6-9 May 2025 for the #EvoDevoTempo conference (2nd edition) with a fantastic line up of speakers confirmed!!
Organized by @mdiazcuadros.bsky.social
@vanderhaeghenp2.bsky.social
@bassemh.bsky.social and me.
Please RT to spread the word
meetings.embo.org/event/25-dev...
Organized by @mdiazcuadros.bsky.social
@vanderhaeghenp2.bsky.social
@bassemh.bsky.social and me.
Please RT to spread the word
meetings.embo.org/event/25-dev...
Developmental timing across species: From mechanisms to evolutionary insights
Like choreography, development consists of a highly ordered suite of steps and transitions. Modifying developmental tempo can affect final size and composition of tissues, as well as their plasticity…
meetings.embo.org
December 20, 2024 at 4:32 PM
Join us in Paris 6-9 May 2025 for the #EvoDevoTempo conference (2nd edition) with a fantastic line up of speakers confirmed!!
Organized by @mdiazcuadros.bsky.social
@vanderhaeghenp2.bsky.social
@bassemh.bsky.social and me.
Please RT to spread the word
meetings.embo.org/event/25-dev...
Organized by @mdiazcuadros.bsky.social
@vanderhaeghenp2.bsky.social
@bassemh.bsky.social and me.
Please RT to spread the word
meetings.embo.org/event/25-dev...
Reposted by The Hassan Brain Development Team
Second edition of the EMBO workshop on Developmental Timing across species.
Second edition organized by
@trayon.bsky.social @bassemh.bsky.social @vanderhaeghenp2.bsky.social and Margerete Diaz-Cuadros
Cool speakers & fun networking activities.
More details coming soon.Save the date:
May 6-9 2025!
Second edition organized by
@trayon.bsky.social @bassemh.bsky.social @vanderhaeghenp2.bsky.social and Margerete Diaz-Cuadros
Cool speakers & fun networking activities.
More details coming soon.Save the date:
May 6-9 2025!
December 1, 2024 at 8:24 PM
Second edition of the EMBO workshop on Developmental Timing across species.
Second edition organized by
@trayon.bsky.social @bassemh.bsky.social @vanderhaeghenp2.bsky.social and Margerete Diaz-Cuadros
Cool speakers & fun networking activities.
More details coming soon.Save the date:
May 6-9 2025!
Second edition organized by
@trayon.bsky.social @bassemh.bsky.social @vanderhaeghenp2.bsky.social and Margerete Diaz-Cuadros
Cool speakers & fun networking activities.
More details coming soon.Save the date:
May 6-9 2025!
This is the Blue Sky account of the Hassan Brain Development lab. Let's connect!
November 25, 2024 at 5:07 PM
This is the Blue Sky account of the Hassan Brain Development lab. Let's connect!