Iryna Mohylyak
@mohylyak.bsky.social
Excited to share our latest paper in Nature Communications! We uncovered a dev-time transcriptional program (via Mirana → Pink1) that shapes mitochondria & circuit wiring.
Disrupt it early, and neurons miswire — even if the gene recovers later!
Disrupt it early, and neurons miswire — even if the gene recovers later!
Latest from the lab, the beautiful work of Iryna Mohylyak and colleagues describing a temporal developmental transcriptional program for mitochondrial quality control and synaptic connectivity, with @jdejuan-sanz.bsky.social, Olga Corti and @steinaerts.bsky.social
labs
www.nature.com/articles/s41...
labs
www.nature.com/articles/s41...
Temporal transcriptional regulation of mitochondrial morphology primes activity-dependent circuit connectivity - Nature Communications
This study investigates the developmental transcriptional regulation of mitochondrial quality control. Authors identify the Drosophila factor Mirana, homologous to mammalian TZAP, as a key temporal re...
www.nature.com
September 16, 2025 at 3:17 PM
Excited to share our latest paper in Nature Communications! We uncovered a dev-time transcriptional program (via Mirana → Pink1) that shapes mitochondria & circuit wiring.
Disrupt it early, and neurons miswire — even if the gene recovers later!
Disrupt it early, and neurons miswire — even if the gene recovers later!