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@prelights.bsky.social
A preprint highlights service run by the biological community and supported by The Company of Biologists (@biologists.bsky.social).
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🚨 New call for preLighters!🚨

Help us highlight the most exciting biological #preprints. Share your insights, build your profile, and be part of a supportive community! 🌍

Interested? Apply today & help shape the future of science publishing! 📢

More info: prelights.biologists.com/news/join-th...
We were delighted to be featured in the latest issue of #BlueSci (@bluescicam.bsky.social) & spotlight a few University of Cambridge students active as part of our community sites @the-node.bsky.social @focalplane.bsky.social

Read BlueSci Issue 62, 'Unseen Worlds', here: www.bluesci.co.uk/issue/
January 19, 2026 at 1:25 PM
Preprints without borders 🌎

Carolina Tanigushi explains how @scielo.org & SciELO Preprints boost #OpenScience across Latin America & beyond, increase visibility for regional research + what (early-career) researchers can do to benefit.

Read the interview: prelights.biologists.com/news/preprin...
Preprints without borders: SciELO Preprints’ push for multilingual, Open Science in Latin America and beyond - preLights
preLights recently spoke with Carolina Tanigushi who now looks after SciELO Preprints, the preprint server that is part of the SciELO Network. We talked about SciELO’s shift into an Open Science progr...
prelights.biologists.com
January 15, 2026 at 11:27 AM
Reposted by preLights
Happy to share our recent preprint:
"DNA-intercalating antiphage molecules trigger abortive infection through mutual destruction and synergize with bacterial immunity"

www.biorxiv.org/content/10.6...

@spp2330.bsky.social, @mibinet.bsky.social, @dfg.de @hhu.de @fzj.bsky.social
January 14, 2026 at 8:57 AM
Reposted by preLights
We are excited to share our new preprint which is now available to read on biorXiv: doi.org/10.64898/202... 🎉🎉🎉
January 13, 2026 at 2:39 PM
Reposted by preLights
Preprints of pandemic potential - new historical piece from me on the history of bioRxiv/medRxiv, their role in the pandemic, and the way forward. 1/n journals.asm.org/doi/10.1128/...
January 12, 2026 at 2:33 PM
Reposted by preLights
Environment & evolution take centre stage at January’s #DevPres

📅 14 January 15:00 GMT/UTC

Three talks, three unique stories. Told by @ethanewe.bsky.social @maxfarnworth.bsky.social @sonyawiden.bsky.social

Chair: @pritiagarwal.bsky.social

🔗Learn more & register: us02web.zoom.us/webinar/regi...
January 12, 2026 at 3:54 PM
KANK2 plays a dual role – dictating cells when to move and when to stick!

@vibhasingh.bsky.social covers recent work from Nikolina Stojanović & colleagues – includes a lovely discussion with the author team.

#preLight ⬇️
prelights.biologists.com/highlights/k...
KANK2 at focal adhesion regulates their maintenance and dynamics, while at fibrillar adhesions it influences cell migration via microtubule-dependent mechanism - preLights
KANK2 plays a dual role – dictating cells when to move and when to stick!
prelights.biologists.com
January 12, 2026 at 4:28 PM
Reposted by preLights
Mind the GAP 🚧🕳️🚧
Excited to share the latest preprint from the Fromme Lab (@fromme-lab.bsky.social), showing that the DENN domain protein Avl9 functions as an Arf-GAP, revising long-standing assumptions about DENN protein function, 🧵:
www.biorxiv.org/content/10.6...
Avl9 defines a family of GTPase-activating proteins that regulate diverse cell biological functions
Ras-related GTPases are molecular switches regulating hundreds of signaling and trafficking pathways in cells. Many GTPase regulators remain to be identified despite extensive genetic and biochemical ...
www.biorxiv.org
January 6, 2026 at 3:38 PM
Unconventional mechanisms of antibiotic action: Stacking and disorganizing. #biochemistry

Leonie Brüne talks to William Stuart & Nicholas J. Harmer #UoEBiosciences about their recent #preprint

Check out the #preLight + insightful discussion ⬇️
prelights.biologists.com/highlights/c...
Cryo-EM reveals multiple mechanisms of ribosome inhibition by doxycycline - preLights
Unconventional mechanisms of antibiotic action: Stacking and disorganizing
prelights.biologists.com
January 7, 2026 at 1:37 PM
Reposted by preLights
In preprints: understanding leaf form for better crop designs

Neha Bhatia from @slcuplants.bsky.social discusses two preprints on soybean leaf development by Chancelor Clark & colleagues and Bishal Tamang & colleagues

doi.org/10.1242/dev....
January 7, 2026 at 10:07 AM
Reposted by preLights
I'm excited to share that our preprint is now available on bioRxiv! Our study challenges the widespread use of molecular genetic diversity as a predictor adaptive potential, with important implications for how genetic data is used to inform conservation decisions.

www.biorxiv.org/content/10.6...
Nucleotide diversity is a poor predictor of short-term adaptive potential
A capacity to adapt is essential for a population to avoid extinction in a changing world and is recognised as a global conservation priority. Adaptation requires additive (heritable) genetic variatio...
www.biorxiv.org
January 6, 2026 at 8:26 AM
From uniform beginnings, junctional heterogeneity and cell-specific mechanics choreograph the stunning diversity of sensory epithelia.

Bhaval Parmar discusses recent work from Anubhav Prakash @prakash-patterns.bsky.social & colleagues. #DevBio

#preLight ⬇️
prelights.biologists.com/highlights/j...
Junctional Heterogeneity Shapes Epithelial Morphospace - preLights
From uniform beginnings, junctional heterogeneity and cell-specific mechanics choreograph the stunning diversity of sensory epithelia.
prelights.biologists.com
January 5, 2026 at 2:40 PM
Reposted by preLights
Extremely excited & proud to share our new preprint - we provide for the first time a single cell map of the mouse brain across sex, the estrous cycle, and peripartum! Data are 🔥 👇

"Single-cell map of the female brain across reproductive transitions"

www.biorxiv.org/content/10.6...
January 4, 2026 at 8:45 PM
Reposted by preLights
Last but certainly not least, our final extraordinary biologist featured is Saanjbati Adhikari, a @dev-journal.bsky.social Reviews Editor, a Cross-Title Features Editor for our 100-year anniversary and a former preLighter @prelights.bsky.social. #100biologists
December 31, 2025 at 7:30 PM
Two more recent preLights were written by Vibha Singh @vibhasingh.bsky.social 🙌

One that discusses Taxane-induced conformational changes in the microtubule lattice. #preprint from Joyce Meiring @joycemeiri.bsky.social and colleagues #UniUtrecht.

#preLight ⬇️
prelights.biologists.com/highlights/t...
Taxane-Induced Conformational Changes in the Microtubule Lattice Activate GEF-H1-Dependent RhoA Signaling - preLights
More than just a stabilizer: Taxanes (cancer drugs) trigger the GEF-H1 – RhoA axis.
prelights.biologists.com
December 31, 2025 at 2:24 PM
Some excellent preLights to end 2025 🎆

The latest was written by Zhang-He Goh @goh-zhanghe.bsky.social, discussing an enzymatic method for tryptophan-specific bromination described in a recent #preprint from the lab of @amyweeks.bsky.social.

#preLight ⬇️
prelights.biologists.com/highlights/e...
Enzymatic bromination of native peptides for late-stage structural diversification via Suzuki-Miyaura coupling - preLights
Ready, set, brominate: RebH and engineered variant for bromination of peptidyl-Trp residues
prelights.biologists.com
December 31, 2025 at 2:14 PM
Check out the latest #preLight from the #preprint review initiative led by Marcus Oliveira #UFRJ #Brazil

⚡Characterising wavelength-selective regulation of keratinocyte metabolism from @aliciakowaltowski.bsky.social & team.

#preLight by Rickson Ribeiro ⬇️👀

prelights.biologists.com/highlights/m...
Mitochondrial Fatty Acid Oxidation is Stimulated by Red Light Irradiation - preLights
Different wavelengths of sunlight can modulate the viability of keratinocytes (Skin cells), and the metabolism. Red light, particularly, affects oxygen consumption during three days post-irradiation a...
prelights.biologists.com
December 19, 2025 at 11:38 AM
The failing heart hides a biochemical vulnerability ❤️‍🩹

Jeny Jose: By linking MGST1 loss to fibroblast activation, ROS accumulation, & ferroptosis susceptibility, this #preprint provides a new perspective on heart failure progression.

#preLight ⬇️
prelights.biologists.com/highlights/l...
Loss of MGST1 during fibroblast differentiation enhances vulnerability to oxidative stress in human heart failure - preLights
The failing heart hides a biochemical vulnerability. MGST1, an antioxidant, down in fibroblasts means a ferroptosis-prone, oxidation-sensitive state. A new therapeutic angle surfaces.
prelights.biologists.com
December 17, 2025 at 8:44 AM
Reposted by preLights
ICYMI, our #preprint list is now up on FocalPlane, highlighting the latest research using #microscopy to answer questions in #biology.
As always, send us any recommendations for preprints that we've missed: focalplane.biologists.com/2025/12/12/m...
Microscopy preprints - applications in biology - FocalPlane
Microscopy preprints - applications in biology - News
focalplane.biologists.com
December 15, 2025 at 11:44 AM
Reposted by preLights
Thrilled to share the preprint from my PhD! 🥳 Where I characterised epithelial cell extrusion in a sea anemone
🔗 www.biorxiv.org/content/10.6...
Big thanks to my supervisor @prhsteinmetz.bsky.social and coauthors @noahbruderer.bsky.social @lionlchristiaen.bsky.social at🇳🇴 @msarscentre.bsky.social ⬇️🧵
December 16, 2025 at 12:33 PM
WHOLISTIC: A whole-body functional atlas of cellular dynamics

@sinanmalik.bsky.social covers work from the @mishaahrens.bsky.social Lab.

“This #preprint represents the kind of transformative science that redefines what is possible in a field.”

#preLight ⬇️
prelights.biologists.com/highlights/i...
Imaging cellular activity simultaneously across all organs of a vertebrate reveals body-wide circuits - preLights
WHOLISTIC: A whole-body functional atlas of cellular dynamics
prelights.biologists.com
December 16, 2025 at 1:59 PM
Fibre for the win: Dietary influences on the gut microbiota 🦠

Jasmine Talevi covers recent work from Blake Dirks & colleagues describing the microbial functional response to two very different diets. #preprint #microbiome

#preLight ⬇️ 👀
prelights.biologists.com/highlights/m...
Microbial Feast or Famine: dietary carbohydrate composition and gut microbiota metabolic function - preLights
Fibre for the win: Dietary influences on the gut microbiota
prelights.biologists.com
December 16, 2025 at 11:53 AM
Reposted by preLights
For our November in #preprints, check out special picks from the list highlighted by preLighters @prelights.bsky.social with expertise across #DevBio and #StemCell biology. Find out why these preLighters are particularly excited about these preprints. ⬇️

thenode.biologists.com/prelighters-...
December 12, 2025 at 11:54 AM
Helping the next generation of scientists find their voice. 📣

Discover how @seahsamantha.bsky.social empowers students through her path from preLights to Executive Editor of the Journal of Emerging Investigators.

Interview: prelights.biologists.com/news/from-pr...
December 11, 2025 at 11:16 AM
Reposted by preLights
💥I am excited to present our first research paper from the lab about caveolae lipid trafficking 🎉 Led by my fantastic PhD candidate @estherocket.bsky.social

Here we looked into caveolae mediated dietary lipid uptake and how this process is mechanistically facilitated 👇 1/n
Lipid-induced Caveolin1-Lipid droplet trafficking is associated with lipid droplet growth https://www.biorxiv.org/content/10.64898/2025.12.10.693432v1
December 11, 2025 at 7:08 AM