Miguel Gómez-Raya
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miguelgrv.bsky.social
Miguel Gómez-Raya
@miguelgrv.bsky.social
350 followers 910 following 19 posts
Postdoc in the Cell Biology and Virology of Archaea Unit @pasteur.fr

Archaea is the coolest domain of life! 🔬🦠

PPU PhD @pasteur.fr, Mart Krupovic
MSc Microbiology @helsinki.fi, Mikael Skurnik
BSc Biomedicine @UB.edu
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miguelgrv.bsky.social
Miguel Gómez-Raya @miguelgrv.bsky.social · Jul 1
Elated to have our pre-print now published in @natcomms.nature.com #ArchaeaSky #Microbiology #MEvoSky
rdcu.be/euila
Our main results stay the same: S. islandicus follows a cell cycle akin to that of some eukaryotes, like the budding yeast, with cellular processes cycling similarly.
old🧵cited below👇
Reposted by Miguel Gómez-Raya
femsjournals.bsky.social
Thermophiles don’t just survive heat, they thrive in it. 🔥

They provide heat-stable enzymes, insights into early Earth, and tools for biotech.

Our new thematic issue in #FEMSMicrobiolEcol captures how diverse this field is. Explore the collection👉 buff.ly/kD8fmOL
November 14, 2025 at 7:00 AM
Reposted by Miguel Gómez-Raya
binomicalabs.org
Any #archaea #archaeasky lab out there interested in having their Natrialba species sequenced on ONT r10 up to about 3Kx read depth for free? I'll send back annotated assembly, methylation data and raw signal files. I need at least one more species for a paper. Feel free to DM!

🧫🦠🧪
November 13, 2025 at 5:00 AM
Reposted by Miguel Gómez-Raya
evgenii-protasov.bsky.social
The most common #methanogen in the human gut, Methanobrevibacter smithii (aka Methanocatella smithii), is the microbe of the month in @cp-trendsmicrobiol.bsky.social
@sgribaldo.bsky.social
#microbiology #archaea #GutMicrobiota #GutMicrobiome
November 10, 2025 at 12:37 PM
Reposted by Miguel Gómez-Raya
danielabarilla.bsky.social
📢 Interested in #chromosomes 🧬 & #archaea thriving at the edge of life? PhD project in York,UK on how archaea pass on their genome to daughter cells.Friendly supervisors: me, @steve-quinn-lab.bsky.social & @georgerheath.bsky.social

www.findaphd.com/phds/project...
📅 January 7, 2026
Please RP🙏thx!
Archaeal cells whose DNA has been stained with a blue dye. Zoomed-in images of mutant cells that display chromosome segregation defects. High-resolution images of DNA-protein complexes obtained with atomic force microscopy. Upon binding, the protein bridges distant sites, forming loops.
November 9, 2025 at 5:20 PM
Reposted by Miguel Gómez-Raya
tbharat-lab.bsky.social
An Asgard archaeon with internal membrane compartments

Brilliant study led by @fmacleod.bsky.social and Andriko von Kügelgen. Tight collaboration with @buzzbaum.bsky.social and lab. Congrats to all authors!

www.biorxiv.org/content/10.1...
November 7, 2025 at 10:44 AM
Reposted by Miguel Gómez-Raya
natmicrobiol.nature.com
Dive into our November issue featuring:

🪆nested archaeal symbioses
🌱microbiota driven drought responses in plants
🏗️ BAM complex in Bacteroidota
💨microbial fermentative growth in the gut
🍸hospital-specific phage therapy cocktail

and much more..!

www.nature.com/nmicrobiol/v...
November 3, 2025 at 4:31 PM
Reposted by Miguel Gómez-Raya
deemteam.bsky.social
This paper has been a must! Great collaboration with @mkrupovic.bsky.social and @yifanzhou.bsky.social, a N&V by a legend of halophilic archaea tinyurl.com/yc3dcv72, and one picture of one of our expeditions to Dallol making the cover of the November issue of @natmicrobiol.nature.com

rdcu.be/eLtCH
November 2, 2025 at 5:52 PM
Reposted by Miguel Gómez-Raya
dudinlab.bsky.social
🚨Our collaboration with @centriolelab.bsky.social & @gautamdey.bsky.social is out today in @cp-cell.bsky.social
We show that #Expansion #Microscopy is a broad-spectrum modality for Euks, enabling 3D phenotypic maps rooted to phylogeny.
#ProtistsOnSky #SciComm #SciSky

www.cell.com/cell/fulltex...
October 31, 2025 at 2:42 PM
Reposted by Miguel Gómez-Raya
dodonova-sveta.bsky.social
Lab’s first paper is out!! We show the first structures of #Asgard #chromatin by #cryo-EM 🧬❄️
Asgard histones form closed and open hypernucleosomes. Closed are conserved across #Archaea, while open resemble eukaryotic H3–H4 octasomes and are Asgard-specific. More here: www.cell.com/molecular-ce...
October 28, 2025 at 3:07 PM
Reposted by Miguel Gómez-Raya
mkrupovic.bsky.social
A nice N&V article by Mike Dyall-Smith on our recent paper
( www.nature.com/articles/s41... ):

www.nature.com/articles/s41...
Archaeal symbioses all the way down - Nature Microbiology
Ethiopian salt lakes feature unique microbial communities with nesting layers of symbioses, where haloarchaea and their ultra-small archaeal symbionts are prey to viruses, which are in turn hijacked b...
www.nature.com
October 20, 2025 at 11:51 AM
Reposted by Miguel Gómez-Raya
yifanzhou.bsky.social
Archaeal symbioses all the way down
by Mike Dyall-Smith

www.nature.com/articles/s41...
Archaeal symbioses all the way down - Nature Microbiology
Ethiopian salt lakes feature unique microbial communities with nesting layers of symbioses, where haloarchaea and their ultra-small archaeal symbionts are prey to viruses, which are in turn hijacked b...
www.nature.com
October 20, 2025 at 10:09 AM
Reposted by Miguel Gómez-Raya
natmicrobiol.nature.com
Viruses and virus satellites of haloarchaea and their nanosized DPANN symbionts reveal intricate nested interactions

Out now in Nature Microbiology, by Yifan Zhou, Mart Krupovic & colleagues.
@mkrupovic.bsky.social
@yifanzhou.bsky.social
@deemteam.bsky.social

www.nature.com/articles/s41...
Viruses and virus satellites of haloarchaea and their nanosized DPANN symbionts reveal intricate nested interactions - Nature Microbiology
An exploration of the viromes of haloarchaea and their ultra-small DPANN symbionts reveals plasmid-derived satellites of viruses from both archaeal groups, highlighting the complexity of nested symbio...
www.nature.com
October 20, 2025 at 7:46 PM
Reposted by Miguel Gómez-Raya
yifanzhou.bsky.social
Our work on viruses and virus satellites of haloarchaea and their DPANN symbionts is out today in Nature Microbiology!
@mkrupovic.bsky.social @deemteam.bsky.social @anagtz.bsky.social
www.nature.com/articles/s41...
Viruses and virus satellites of haloarchaea and their nanosized DPANN symbionts reveal intricate nested interactions - Nature Microbiology
An exploration of the viromes of haloarchaea and their ultra-small DPANN symbionts reveals plasmid-derived satellites of viruses from both archaeal groups, highlighting the complexity of nested symbio...
www.nature.com
October 17, 2025 at 9:54 AM
Reposted by Miguel Gómez-Raya
mkrupovic.bsky.social
Check out our paper on intricate nested interactions between viruses and virus satellites of haloarchaea and their nanosized DPANN symbionts. Excellent collaboration with @deemteam.bsky.social, @anagtz.bsky.social and Michail Yakimov
Free access link: rdcu.be/eLtCH
🧵 by @yifanzhou.bsky.social 👇
October 17, 2025 at 10:28 AM
Reposted by Miguel Gómez-Raya
vsorichetti.bsky.social
Our paper on chromosome segregation in the archaeon Sulfolobus Acidocaldarius has been published in PNAS! This has been a great collaboration with @joeparham19.bsky.social and the rest of @buzzbaum.bsky.social's team. Stay tuned for more to come!😉 @istaresearch.bsky.social

doi.org/10.1073/pnas...
Temporal and spatial coordination of DNA segregation and cell division in an archaeon | PNAS
Cells must coordinate DNA segregation with cytokinesis to ensure that each daughter cell inherits a complete genome. Here, we explore how DNA segre...
doi.org
October 16, 2025 at 8:53 AM
Reposted by Miguel Gómez-Raya
plosbiology.org
Persistent viral #infections in #insects are not as harmless as once believed. @salehlabparis.bsky.social &co show how such infections in #FruitFlies alter survival, reproduction, behavior & gene expression, revealing the hidden costs of #viral persistence @plosbiology.org 🧪 plos.io/4olpuXm
Cartoon illustration depicting a sick Drosophila melanogaster surrounded by different viruses, symbolizing the impact of persistent viral infections on the model organism. Image credit Rubén González.
October 13, 2025 at 1:08 PM
Reposted by Miguel Gómez-Raya
salehlabparis.bsky.social
So happy to see this in print! Led by the brilliant (almost Dr.) @castellosanjuan.bsky.social, with the amazing guidance of @rubengonzalez.bsky.social & @jarednigg.bsky.social.
We used to think persistent infections were harmless… but our latest work shows otherwise. Read it to learn more!
plosbiology.org PLOS Biology @plosbiology.org · Oct 13
Persistent viral #infections in #insects are not as harmless as once believed. @salehlabparis.bsky.social &co show how such infections in #FruitFlies alter survival, reproduction, behavior & gene expression, revealing the hidden costs of #viral persistence @plosbiology.org 🧪 plos.io/4olpuXm
Cartoon illustration depicting a sick Drosophila melanogaster surrounded by different viruses, symbolizing the impact of persistent viral infections on the model organism. Image credit Rubén González.
October 13, 2025 at 8:23 PM
Reposted by Miguel Gómez-Raya
cryoclem.bsky.social
Our work on ribosome hibernation in archaea is out!
We identified Hib, a new hibernation factor broadly distributed across archaea.
Check out the preprint 👉 biorxiv.org/content/10.1101/2025.10.11.676729v1
(1/🧵)
October 13, 2025 at 4:26 PM
Reposted by Miguel Gómez-Raya
filiphusnik.bsky.social
Pretty excited to share our new preprint!
Non-photosynthetic Plastid Replacement by a Primary Plastid in the Making
www.biorxiv.org/content/10.1...
October 10, 2025 at 3:34 AM
Reposted by Miguel Gómez-Raya
erinedoherty.bsky.social
Now online at @nature.com we show how the Panoptes defense system protects against viruses that attempt immune evasion - and expands our understanding of the role of oligonucleotides in immunity.

Check out this work co-led with @benadler.bsky.social here:

www.nature.com/articles/s41...
A miniature CRISPR–Cas10 enzyme confers immunity by inhibitory signalling - Nature
Panoptes, an anti-phage defence system against virus-mediated immune suppression, is revealed.
www.nature.com
October 2, 2025 at 3:01 AM
Reposted by Miguel Gómez-Raya
francoismayer.bsky.social
Our October issue is out now!

The images are negatively stained electron micrographs taken from archaella bundles isolated from the archaeon Sulfolobus acidocaldarius.

Check the issue out here:
www.nature.com/nmicrobiol/v...
October 1, 2025 at 9:26 PM
Reposted by Miguel Gómez-Raya
benmorehouse.bsky.social
Our story describing the Panoptes bacterial immune defense system is now finally peer-reviewed and published today! www.nature.com/articles/s41...
The Panoptes system uses decoy cyclic nucleotides to defend against phage - Nature
The Panoptes antiphage system defends bacteria by detecting phage-encoded counter-defences that sequester cyclic nucleotide signals, triggering membrane disruption and highlighting a broader strategy of sensing immune evasion through second-messenger surveillance.
www.nature.com
October 1, 2025 at 4:05 PM
Reposted by Miguel Gómez-Raya
cemess.bsky.social
Who fixes carbon in the dark ocean? A new study in @nature.com, led by @barbarabayer.bsky.social @univie.ac.at shows that ammonia‐oxidizing microbes contribute much less to dark carbon fixation than previously thought – leaving room for unknown players.
Read more: 🔗 dome.univie.ac.at/news-events/...
Who fixes carbon in the dark ocean?
A new study led by Barbara Bayer (CeMESS, University of Vienna) discovered that ammonia-oxidizing microorganisms contribute much less to carbon fixation in the ocean than previously assumed. The study...
dome.univie.ac.at
September 23, 2025 at 9:47 AM
Reposted by Miguel Gómez-Raya
arnausebe.bsky.social
Happy to share the Biodiversity Cell Atlas white paper, out today in @nature.com. We look at the possibilities, challenges, and potential impacts of molecularly mapping cells across the tree of life.
www.nature.com/articles/s41...
September 24, 2025 at 3:12 PM
Reposted by Miguel Gómez-Raya
mmarbout.bsky.social
You like phages ? In this publication, we use metaHiC and our new version of the MetaTOR pipeline to challenge the traditional view of phages with a narrow host range.
@rkoszul.bsky.social @natmicrobiol.nature.com @cnrs.fr @institutpasteur.bsky.social

www.nature.com/articles/s41...
Phages with a broad host range are common across ecosystems - Nature Microbiology
Proximity-ligation-based sequencing from 111 samples and 5 environments reveals that a substantial proportion of phages infect multiple species.
www.nature.com
September 19, 2025 at 9:32 AM