Saba
@microsaba.bsky.social
Reposted by Saba
A comprehensive review on covalent chemical strategies for protein self-labeling from @kjohnsson.bsky.social's lab: HaloTag, SNAP-tag et al. www.annualreviews.org/content/jour...
March 20, 2025 at 8:56 PM
A comprehensive review on covalent chemical strategies for protein self-labeling from @kjohnsson.bsky.social's lab: HaloTag, SNAP-tag et al. www.annualreviews.org/content/jour...
Reposted by Saba
Bluetorial: Mentors: The long-serving dean
Art Levine was a great leader, first at NIH, and then at the University of Pittsburgh
He is a great mentor to me and others and a scientist's scientist
(A long palate cleanser for today)
Art Levine was a great leader, first at NIH, and then at the University of Pittsburgh
He is a great mentor to me and others and a scientist's scientist
(A long palate cleanser for today)
a cartoon says hey everybody an old man 's talking while bart simpson looks on
ALT: a cartoon says hey everybody an old man 's talking while bart simpson looks on
media.tenor.com
March 13, 2025 at 12:22 PM
Bluetorial: Mentors: The long-serving dean
Art Levine was a great leader, first at NIH, and then at the University of Pittsburgh
He is a great mentor to me and others and a scientist's scientist
(A long palate cleanser for today)
Art Levine was a great leader, first at NIH, and then at the University of Pittsburgh
He is a great mentor to me and others and a scientist's scientist
(A long palate cleanser for today)
Reposted by Saba
🎉 30 Years of Single Molecule Science🎉 Join us for the 30th Single Molecule Workshop with Nobel Laureates Stefan Hell and W. E. Moerner. Present your research and connect.
📅 Abstracts: April 16, 2025
📅 Workshop: Sept 23–26, 2025 | Berlin
🔗 www.single-molecules.org
#️⃣ #singlemolecules #microscopy
📅 Abstracts: April 16, 2025
📅 Workshop: Sept 23–26, 2025 | Berlin
🔗 www.single-molecules.org
#️⃣ #singlemolecules #microscopy
March 6, 2025 at 11:30 AM
🎉 30 Years of Single Molecule Science🎉 Join us for the 30th Single Molecule Workshop with Nobel Laureates Stefan Hell and W. E. Moerner. Present your research and connect.
📅 Abstracts: April 16, 2025
📅 Workshop: Sept 23–26, 2025 | Berlin
🔗 www.single-molecules.org
#️⃣ #singlemolecules #microscopy
📅 Abstracts: April 16, 2025
📅 Workshop: Sept 23–26, 2025 | Berlin
🔗 www.single-molecules.org
#️⃣ #singlemolecules #microscopy
Reposted by Saba
A wonderful meeting to share the latest developments on single-molecule research, network, and generate new ideas! Great invited speakers @sulianamanley.bsky.social @jungmannlab.bsky.social, David Rueda, Sebastian Diendl! Send us your Abstracts by *March 7th*!
Following the great success of the 2024 event, @ox.ac.uk and LUMICKS proudly present the second UK-Ireland symposium focusing on single-molecule research!
The abstract deadline, 7 March, is approaching fast. Secure a talk or poster by registering now > bit.ly/4gYPPpQ
The abstract deadline, 7 March, is approaching fast. Secure a talk or poster by registering now > bit.ly/4gYPPpQ
March 4, 2025 at 2:29 PM
A wonderful meeting to share the latest developments on single-molecule research, network, and generate new ideas! Great invited speakers @sulianamanley.bsky.social @jungmannlab.bsky.social, David Rueda, Sebastian Diendl! Send us your Abstracts by *March 7th*!
Reposted by Saba
Thank you to the fantastic speakers who presented today at our first meeting!
We are now accepting submissions for our second meeting on April 7th.
Submission link : forms.gle/SBeQeAp9MR2U...
We are now accepting submissions for our second meeting on April 7th.
Submission link : forms.gle/SBeQeAp9MR2U...
March 3, 2025 at 11:44 PM
Thank you to the fantastic speakers who presented today at our first meeting!
We are now accepting submissions for our second meeting on April 7th.
Submission link : forms.gle/SBeQeAp9MR2U...
We are now accepting submissions for our second meeting on April 7th.
Submission link : forms.gle/SBeQeAp9MR2U...
Reposted by Saba
Here's a set of three for #FluorescenceFriday. Same image, progressively higher zoom. FFPE human tonsil tissue labeled with primary antibodies against Cytokeratin, PCNA, C20, CD45RB, CD68, eCadherin, and SMA. 🧪🔬
March 1, 2025 at 5:31 AM
Here's a set of three for #FluorescenceFriday. Same image, progressively higher zoom. FFPE human tonsil tissue labeled with primary antibodies against Cytokeratin, PCNA, C20, CD45RB, CD68, eCadherin, and SMA. 🧪🔬
Reposted by Saba
Every scientist, long before they were a scientist, was a little kid who stood in front of a fish tank or stared up at the stars or turned over a rock to look at the bugs underneath and said “wow”. On the best days, working in science still feels like that.
February 19, 2025 at 2:08 AM
Every scientist, long before they were a scientist, was a little kid who stood in front of a fish tank or stared up at the stars or turned over a rock to look at the bugs underneath and said “wow”. On the best days, working in science still feels like that.
Reposted by Saba
DNA-PAINT imaging with hydrogel imprinting and clearing https://www.biorxiv.org/content/10.1101/2025.02.14.638341v1
February 17, 2025 at 10:48 AM
DNA-PAINT imaging with hydrogel imprinting and clearing https://www.biorxiv.org/content/10.1101/2025.02.14.638341v1
Reposted by Saba
After a long journey, Segment Anything for Microscopy is now published in Nature Methods! We significantly improve SAM for interactive and automatic segmentation in light and electron microscopy and build a user-friendly tool.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
February 12, 2025 at 11:41 AM
After a long journey, Segment Anything for Microscopy is now published in Nature Methods! We significantly improve SAM for interactive and automatic segmentation in light and electron microscopy and build a user-friendly tool.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Saba
ÅNGSTRÖM-RESOLUTION IMAGING OF CELL-SURFACE GLYCANS 🧬🎨🍬
The glycocalyx, our cells' sugar coat, holds secrets in immunology, cancer, viral infections, and more. Visualizing its molecular architecture was impossible… until now. #glycotime #microscopy
www.biorxiv.org/content/10.1...
The glycocalyx, our cells' sugar coat, holds secrets in immunology, cancer, viral infections, and more. Visualizing its molecular architecture was impossible… until now. #glycotime #microscopy
www.biorxiv.org/content/10.1...
February 10, 2025 at 8:21 AM
ÅNGSTRÖM-RESOLUTION IMAGING OF CELL-SURFACE GLYCANS 🧬🎨🍬
The glycocalyx, our cells' sugar coat, holds secrets in immunology, cancer, viral infections, and more. Visualizing its molecular architecture was impossible… until now. #glycotime #microscopy
www.biorxiv.org/content/10.1...
The glycocalyx, our cells' sugar coat, holds secrets in immunology, cancer, viral infections, and more. Visualizing its molecular architecture was impossible… until now. #glycotime #microscopy
www.biorxiv.org/content/10.1...
Reposted by Saba
For those of you running system quality control measurements: New publication from QUAREP-LiMi for illumination power, stability and linearity measurements
www.protocols.io/view/illumin...
www.protocols.io/view/illumin...
Illumination Power, Stability, and Linearity Measurements for Confocal, Widefield and Multiphoton Microscopes
To obtain accurate, reproducible, and interpretable data when conducting imaging experiments, it is critical to consider external factors affecting data acquisition at vario...
www.protocols.io
January 28, 2025 at 2:39 PM
For those of you running system quality control measurements: New publication from QUAREP-LiMi for illumination power, stability and linearity measurements
www.protocols.io/view/illumin...
www.protocols.io/view/illumin...
Reposted by Saba
More details on Newcastle University redundancies. Of the 300 FTEs to be lost, a proposed 50/50 split between academic and administrative posts. This is 5% of the workforce. 40 posts to be lost from Academic Hub (student study skills and advice). 1/3
Cutting unfunded research ‘hits Newcastle Russell Group standing’
Questions raised about institution’s research reputation as it seeks to reduce academics’ research hours to plug £20 million black hole
www.timeshighereducation.com
January 28, 2025 at 8:18 AM
More details on Newcastle University redundancies. Of the 300 FTEs to be lost, a proposed 50/50 split between academic and administrative posts. This is 5% of the workforce. 40 posts to be lost from Academic Hub (student study skills and advice). 1/3
Reposted by Saba
🅲🅾🅾🅻 🆃🅴🅲🅷🅽🅾🅻🅾🅶🆈
“Bacterial-MERFISH” provides ~1000-fold volumetric expansion of individual cells, charts gene expression in hundreds of thousands of cells, deciphering bacterial single-cell heterogeneity, intracellular transcriptome organization, and bacterial adaptation to µm-scale niches in vivo
“Bacterial-MERFISH” provides ~1000-fold volumetric expansion of individual cells, charts gene expression in hundreds of thousands of cells, deciphering bacterial single-cell heterogeneity, intracellular transcriptome organization, and bacterial adaptation to µm-scale niches in vivo
Highly multiplexed spatial transcriptomics in bacteria
Single-cell decisions made in complex environments underlie many bacterial phenomena. Image-based transcriptomics approaches offer an avenue to study such behaviors, yet these approaches have been hin...
www.science.org
January 25, 2025 at 5:33 PM
🅲🅾🅾🅻 🆃🅴🅲🅷🅽🅾🅻🅾🅶🆈
“Bacterial-MERFISH” provides ~1000-fold volumetric expansion of individual cells, charts gene expression in hundreds of thousands of cells, deciphering bacterial single-cell heterogeneity, intracellular transcriptome organization, and bacterial adaptation to µm-scale niches in vivo
“Bacterial-MERFISH” provides ~1000-fold volumetric expansion of individual cells, charts gene expression in hundreds of thousands of cells, deciphering bacterial single-cell heterogeneity, intracellular transcriptome organization, and bacterial adaptation to µm-scale niches in vivo
Reposted by Saba
Super resolution confocal image of a lateral line neuromast in a 5-day-old zebrafish 🐟
The green dots are amazing specialized presynaptic structures called synaptic ribbons 🎀
Hair cell actin labeled in orange, acetylated tubulin in neurons & hair cells labeled in purple #FluorescenceFriday
The green dots are amazing specialized presynaptic structures called synaptic ribbons 🎀
Hair cell actin labeled in orange, acetylated tubulin in neurons & hair cells labeled in purple #FluorescenceFriday
January 24, 2025 at 4:58 PM
Super resolution confocal image of a lateral line neuromast in a 5-day-old zebrafish 🐟
The green dots are amazing specialized presynaptic structures called synaptic ribbons 🎀
Hair cell actin labeled in orange, acetylated tubulin in neurons & hair cells labeled in purple #FluorescenceFriday
The green dots are amazing specialized presynaptic structures called synaptic ribbons 🎀
Hair cell actin labeled in orange, acetylated tubulin in neurons & hair cells labeled in purple #FluorescenceFriday
Reposted by Saba
I’ve said “right” about 10 separate times this morning in a bid to get myself going. It’s the British person version of repeatedly yanking the starter cord on an old lawnmower.
January 20, 2025 at 8:24 AM
I’ve said “right” about 10 separate times this morning in a bid to get myself going. It’s the British person version of repeatedly yanking the starter cord on an old lawnmower.
Reposted by Saba
A pair of COS cells, one in interphase and one in mitosis for
#FluorescenceFriday. Tricky 4-channel overlay made possible by @kwolbachia.bsky.social LUTs! Microtubules 🟣 vimentin 🟢 mitochondria 🟠 clathrin 🔵, deconvolved Apotome.
#FluorescenceFriday. Tricky 4-channel overlay made possible by @kwolbachia.bsky.social LUTs! Microtubules 🟣 vimentin 🟢 mitochondria 🟠 clathrin 🔵, deconvolved Apotome.
January 17, 2025 at 1:03 PM
A pair of COS cells, one in interphase and one in mitosis for
#FluorescenceFriday. Tricky 4-channel overlay made possible by @kwolbachia.bsky.social LUTs! Microtubules 🟣 vimentin 🟢 mitochondria 🟠 clathrin 🔵, deconvolved Apotome.
#FluorescenceFriday. Tricky 4-channel overlay made possible by @kwolbachia.bsky.social LUTs! Microtubules 🟣 vimentin 🟢 mitochondria 🟠 clathrin 🔵, deconvolved Apotome.
Reposted by Saba
Confirmed speakers for the next Great Wall Symposium is coming along! thegreatwall-symposium.org/program/
Abstracts will open next week 15th so start thinking!
September 15-17th, Catania, Sicily
Its a Microbiological opportunity you cant refuse!
Abstracts will open next week 15th so start thinking!
September 15-17th, Catania, Sicily
Its a Microbiological opportunity you cant refuse!
January 10, 2025 at 9:44 AM
Confirmed speakers for the next Great Wall Symposium is coming along! thegreatwall-symposium.org/program/
Abstracts will open next week 15th so start thinking!
September 15-17th, Catania, Sicily
Its a Microbiological opportunity you cant refuse!
Abstracts will open next week 15th so start thinking!
September 15-17th, Catania, Sicily
Its a Microbiological opportunity you cant refuse!
Reposted by Saba
Reposted by Saba
Delighted to hear that Andrew McMahon and Nicole Robb's study 'Engineering stress as a motivation for filamentous virus morphology,' which we and other @cvrinfo.bsky.social authors collaborated in, is now a beautiful cover image. You can read the paper here: www.sciencedirect.com/science/arti...
December 11, 2024 at 3:58 PM
Delighted to hear that Andrew McMahon and Nicole Robb's study 'Engineering stress as a motivation for filamentous virus morphology,' which we and other @cvrinfo.bsky.social authors collaborated in, is now a beautiful cover image. You can read the paper here: www.sciencedirect.com/science/arti...
Reposted by Saba
Bluesky: Revising my PhD thesis, 41 years later.
Just before the holidays, I discovered a paper I had missed (from 25 years ago) that showed that a major interpretation from my dissertation was wrong. I now have things sorted and the results are quite interesting, maybe better than the original.
Just before the holidays, I discovered a paper I had missed (from 25 years ago) that showed that a major interpretation from my dissertation was wrong. I now have things sorted and the results are quite interesting, maybe better than the original.
a cartoon says hey everybody an old man 's talking while bart simpson looks on
ALT: a cartoon says hey everybody an old man 's talking while bart simpson looks on
media.tenor.com
January 9, 2025 at 1:25 PM
Bluesky: Revising my PhD thesis, 41 years later.
Just before the holidays, I discovered a paper I had missed (from 25 years ago) that showed that a major interpretation from my dissertation was wrong. I now have things sorted and the results are quite interesting, maybe better than the original.
Just before the holidays, I discovered a paper I had missed (from 25 years ago) that showed that a major interpretation from my dissertation was wrong. I now have things sorted and the results are quite interesting, maybe better than the original.
Reposted by Saba
May your holidays sparkle as much as Alexa647 💖
December 24, 2024 at 3:52 PM
May your holidays sparkle as much as Alexa647 💖
Reposted by Saba
2024 Headline of the Year nominee (January)
December 22, 2024 at 7:14 PM
2024 Headline of the Year nominee (January)
Reposted by Saba
Hi Bluesky community! 👋
Are you looking forward to 2025 as much as we are? 👀
We just updated our 2025 Annual Poster to include even more events for you to join, so go and have a look!
➡️ s.embl.org/poster-bl
#EMBLEvents #molecularbiology #lifesciencetraining
Are you looking forward to 2025 as much as we are? 👀
We just updated our 2025 Annual Poster to include even more events for you to join, so go and have a look!
➡️ s.embl.org/poster-bl
#EMBLEvents #molecularbiology #lifesciencetraining
December 13, 2024 at 9:06 AM
Hi Bluesky community! 👋
Are you looking forward to 2025 as much as we are? 👀
We just updated our 2025 Annual Poster to include even more events for you to join, so go and have a look!
➡️ s.embl.org/poster-bl
#EMBLEvents #molecularbiology #lifesciencetraining
Are you looking forward to 2025 as much as we are? 👀
We just updated our 2025 Annual Poster to include even more events for you to join, so go and have a look!
➡️ s.embl.org/poster-bl
#EMBLEvents #molecularbiology #lifesciencetraining
Reposted by Saba
Full spectrum of ‘zebrabow’ embryos. Credit to @jhenninger.bsky.social. #ZebrafishZunday 🧪
December 15, 2024 at 1:25 PM
Full spectrum of ‘zebrabow’ embryos. Credit to @jhenninger.bsky.social. #ZebrafishZunday 🧪
Reposted by Saba
For today's #FluorescenceFriday it's a frog embryo!
December 13, 2024 at 6:41 PM
For today's #FluorescenceFriday it's a frog embryo!