Ricardo Henriques
@henriqueslab.bsky.social
@AIOpticalBioLab.bsky.social. Group Leader #ITQB & H. Prof #UCL. #Nanoscopy & #AI for #LifeSciences. #SRRF sensei. #ERCCoG, #EMBO member. Dad. Opinions my own
- henriqueslab.org -
- henriqueslab.org -
Pinned
🚨🔬🤖🚀 #PhotoFiTT is out! With @guijacquemet.bsky.social's & @microbematos.bsky.social's labs, we launched a new phototoxicity measurement for live microscopy using cell clocks⏱️. By rockstars @mariodelr.bsky.social @gomez-mariscal.bsky.social et al! AI-powered + label-free
doi.org/10.1038/s414...
doi.org/10.1038/s414...
Reposted by Ricardo Henriques
One of my favorites features is that you can now cite using DOI in line with the text. #RxivMaker automatically fetches the citation and update your documents. No more messing around with Biblitex ❤️
🚀📰 End-of-year news for #RxivMaker =). Now it generates both #pdf and #docx from #markdown. Docx makes it easier to collaborate on a document for non-markdown users, making it simple to loop between docx and #RxivMaker to a professional-looking #preprint
Preprint updated: arxiv.org/abs/2508.00836
Preprint updated: arxiv.org/abs/2508.00836
December 19, 2025 at 6:33 PM
One of my favorites features is that you can now cite using DOI in line with the text. #RxivMaker automatically fetches the citation and update your documents. No more messing around with Biblitex ❤️
🚀📰 End-of-year news for #RxivMaker =). Now it generates both #pdf and #docx from #markdown. Docx makes it easier to collaborate on a document for non-markdown users, making it simple to loop between docx and #RxivMaker to a professional-looking #preprint
Preprint updated: arxiv.org/abs/2508.00836
Preprint updated: arxiv.org/abs/2508.00836
December 19, 2025 at 11:20 AM
🚀📰 End-of-year news for #RxivMaker =). Now it generates both #pdf and #docx from #markdown. Docx makes it easier to collaborate on a document for non-markdown users, making it simple to loop between docx and #RxivMaker to a professional-looking #preprint
Preprint updated: arxiv.org/abs/2508.00836
Preprint updated: arxiv.org/abs/2508.00836
Reposted by Ricardo Henriques
On my last day in the lab for 2025… I sneak into the h-index 40 club to join @henriqueslab.bsky.social!
#celebrateallthethings
#celebrateallthethings
December 19, 2025 at 9:57 AM
On my last day in the lab for 2025… I sneak into the h-index 40 club to join @henriqueslab.bsky.social!
#celebrateallthethings
#celebrateallthethings
🧬 @itqbnova.bsky.social has 15 BRIDGE fellowships for Master's graduates pursuing PhDs!
We have a spot: "Decoding the morphological language of infection using AI". Build AI to map how viruses hijack cells & bacteria survive antibiotics.
Deadline: 05/01/2026
www.itqb.unl.pt/education/br...
We have a spot: "Decoding the morphological language of infection using AI". Build AI to map how viruses hijack cells & bacteria survive antibiotics.
Deadline: 05/01/2026
www.itqb.unl.pt/education/br...
December 19, 2025 at 9:54 AM
🧬 @itqbnova.bsky.social has 15 BRIDGE fellowships for Master's graduates pursuing PhDs!
We have a spot: "Decoding the morphological language of infection using AI". Build AI to map how viruses hijack cells & bacteria survive antibiotics.
Deadline: 05/01/2026
www.itqb.unl.pt/education/br...
We have a spot: "Decoding the morphological language of infection using AI". Build AI to map how viruses hijack cells & bacteria survive antibiotics.
Deadline: 05/01/2026
www.itqb.unl.pt/education/br...
Going through my UCL-times photos, this little one came up
December 15, 2025 at 5:49 PM
Going through my UCL-times photos, this little one came up
Reposted by Ricardo Henriques
🛠️Why this matters: PhotoFiTT empowers labs to fine-tune imaging conditions, improve reproducibility, reduce cell stress, and strengthen biological conclusions. All code, data & tools are open on GitHub & BioArchive 🔓📦 #OpenScience 👉 github.com/HenriquesLab...
December 15, 2025 at 2:58 PM
🛠️Why this matters: PhotoFiTT empowers labs to fine-tune imaging conditions, improve reproducibility, reduce cell stress, and strengthen biological conclusions. All code, data & tools are open on GitHub & BioArchive 🔓📦 #OpenScience 👉 github.com/HenriquesLab...
Reposted by Ricardo Henriques
💡 Key insights we uncovered: Near-UV light delays mitosis at doses as low as 0.6 J/cm². Longer wavelengths need higher doses, and surprisingly, continuous low-intensity illumination (slow scan) can be more damaging than brief high-intensity bursts (fast scan). Data-driven phototoxicity thresholds! ✨
December 15, 2025 at 2:58 PM
💡 Key insights we uncovered: Near-UV light delays mitosis at doses as low as 0.6 J/cm². Longer wavelengths need higher doses, and surprisingly, continuous low-intensity illumination (slow scan) can be more damaging than brief high-intensity bursts (fast scan). Data-driven phototoxicity thresholds! ✨
Reposted by Ricardo Henriques
🚀 Enter PhotoFiTT: a standardise experimental protocol combined with AI-powered image analysis to track cell behaviour (mitosis, size, activity) in response to light exposure. What’s even better: label-free and fully quantitative! 🔍🤖
December 15, 2025 at 2:58 PM
🚀 Enter PhotoFiTT: a standardise experimental protocol combined with AI-powered image analysis to track cell behaviour (mitosis, size, activity) in response to light exposure. What’s even better: label-free and fully quantitative! 🔍🤖
Reposted by Ricardo Henriques
The challenge: live-cell fluorescence microscopy can unintentionally stress or harm cells, changing timing, size and activity. If left unchecked, this can skew biology and standard qualitative checks just don’t cut it ⚡️ #Microscopy #CellBiology
December 15, 2025 at 2:58 PM
The challenge: live-cell fluorescence microscopy can unintentionally stress or harm cells, changing timing, size and activity. If left unchecked, this can skew biology and standard qualitative checks just don’t cut it ⚡️ #Microscopy #CellBiology
Reposted by Ricardo Henriques
It’s FINALLY out! 🎉🚀 We have been working on PhotoFiTT for a long time, and it’s now published, introducing a quantitative framework to measure phototoxicity and optimise live-cell microscopy experiments. So excited to finally share the last version! 🔬✨ #PhotoFiTT doi.org/10.1038/s414...
December 15, 2025 at 2:58 PM
It’s FINALLY out! 🎉🚀 We have been working on PhotoFiTT for a long time, and it’s now published, introducing a quantitative framework to measure phototoxicity and optimise live-cell microscopy experiments. So excited to finally share the last version! 🔬✨ #PhotoFiTT doi.org/10.1038/s414...
Reposted by Ricardo Henriques
#PhotoFiTT proposes a standard label-free and quantitative protocol, including #AIImageProcessing, to measure #phototoxicity derived cell stress 🧮 By systematically assessing deviations in cell behaviour, we can optimize #livecell experiments and stop blindly frying our cells💡🧫
two eggs with faces drawn on them in a frying pan with the words the egging dead below them
ALT: two eggs with faces drawn on them in a frying pan with the words the egging dead below them
media.tenor.com
December 15, 2025 at 2:58 PM
#PhotoFiTT proposes a standard label-free and quantitative protocol, including #AIImageProcessing, to measure #phototoxicity derived cell stress 🧮 By systematically assessing deviations in cell behaviour, we can optimize #livecell experiments and stop blindly frying our cells💡🧫
Reposted by Ricardo Henriques
🚨Amazing news for a cloudy Monday!🌩️😎 I'm extremely happy to share that our last adventure is finally out!🚀🎉Phototoxicity fitness time trial (#PhotoFiTT) - a quantitative framework for assessing phototoxicity in live-cell microscopy experiments 🔬❤️🔥⚡️ doi.org/10.1038/s414...
December 15, 2025 at 2:58 PM
🚨Amazing news for a cloudy Monday!🌩️😎 I'm extremely happy to share that our last adventure is finally out!🚀🎉Phototoxicity fitness time trial (#PhotoFiTT) - a quantitative framework for assessing phototoxicity in live-cell microscopy experiments 🔬❤️🔥⚡️ doi.org/10.1038/s414...
Reposted by Ricardo Henriques
We hope #PhotoFiTT becomes part of your standard toolkit for benchmarking phototoxicity⚖️reporting light exposure✅+sharing more reproducible imaging results🦾May quantitative phototoxicity assessment be a norm, not an afterthought✨ User-friendly code👩💻👉 github.com/HenriquesLab...
GitHub - HenriquesLab/PhotoFiTT: Computational workflows to assess phototoxicity in live-cell microscopy experiments
Computational workflows to assess phototoxicity in live-cell microscopy experiments - HenriquesLab/PhotoFiTT
github.com
December 15, 2025 at 2:58 PM
We hope #PhotoFiTT becomes part of your standard toolkit for benchmarking phototoxicity⚖️reporting light exposure✅+sharing more reproducible imaging results🦾May quantitative phototoxicity assessment be a norm, not an afterthought✨ User-friendly code👩💻👉 github.com/HenriquesLab...
Reposted by Ricardo Henriques
Huge thanks to all the amazing co-authors Leonor Morgado, Raquel Portela @guijacquemet.bsky.social and @microbematos.bsky.social @aiopticalbiolab.bsky.social 🌸💖🙏
December 15, 2025 at 2:58 PM
Huge thanks to all the amazing co-authors Leonor Morgado, Raquel Portela @guijacquemet.bsky.social and @microbematos.bsky.social @aiopticalbiolab.bsky.social 🌸💖🙏
Reposted by Ricardo Henriques
As if a full photodamage odyssey wasn’t enough😏, we also had the excitement of moving institutes mid-project to @itqbnova.bsky.social 💚 New place, new microscopes, new experiments, new prizes and yet more fun!🤩
December 15, 2025 at 2:58 PM
As if a full photodamage odyssey wasn’t enough😏, we also had the excitement of moving institutes mid-project to @itqbnova.bsky.social 💚 New place, new microscopes, new experiments, new prizes and yet more fun!🤩
Reposted by Ricardo Henriques
With the best partner in crime
@mariodelr.bsky.social😎 this adventure started when joining @henriqueslab.bsky.social
From day-1, #phototoxicity was a nightmare+obsession, but also as much about deep learning (beyond images), endless discussions+experiments and true joy as it was about microscopy 🔬💪
@mariodelr.bsky.social😎 this adventure started when joining @henriqueslab.bsky.social
From day-1, #phototoxicity was a nightmare+obsession, but also as much about deep learning (beyond images), endless discussions+experiments and true joy as it was about microscopy 🔬💪
December 15, 2025 at 2:58 PM
With the best partner in crime
@mariodelr.bsky.social😎 this adventure started when joining @henriqueslab.bsky.social
From day-1, #phototoxicity was a nightmare+obsession, but also as much about deep learning (beyond images), endless discussions+experiments and true joy as it was about microscopy 🔬💪
@mariodelr.bsky.social😎 this adventure started when joining @henriqueslab.bsky.social
From day-1, #phototoxicity was a nightmare+obsession, but also as much about deep learning (beyond images), endless discussions+experiments and true joy as it was about microscopy 🔬💪
Reposted by Ricardo Henriques
🎉 Last but not least, a huge thanks to @gomez-mariscal.bsky.social Leonor Morgado, Raquel Portela, @guijacquemet.bsky.social @microbematos.bsky.social @henriqueslab.bsky.social
We have been an amazing team, and you made this work possible! 🥳🚀
We have been an amazing team, and you made this work possible! 🥳🚀
December 15, 2025 at 2:58 PM
🎉 Last but not least, a huge thanks to @gomez-mariscal.bsky.social Leonor Morgado, Raquel Portela, @guijacquemet.bsky.social @microbematos.bsky.social @henriqueslab.bsky.social
We have been an amazing team, and you made this work possible! 🥳🚀
We have been an amazing team, and you made this work possible! 🥳🚀
Reposted by Ricardo Henriques
Our Researcher @mariodelr.bsky.social and Raquel Portela from @microbematos.bsky.social were invited by @healthnewspt.bsky.social to talk about their new collaboration project awarded by Early Career Research Award, 𝗜𝗻𝗳𝗲𝗰𝘁𝗼𝗙𝗶𝗧𝗧.
Read the full interview at: tinyurl.com/infectofitt
Read the full interview at: tinyurl.com/infectofitt
Raquel Portela e Mario del Rosario, ITQB NOVA: “Transformar o microscópio num sensor inteligente”
Em entrevista exclusiva ao Healthnews, os investigadores Raquel Portela e Mario del Rosario do ITQB NOVA apresentam o InfectoFiTT, uma ferramenta de IA que monitoriza em tempo real o impacto das infeç...
tinyurl.com
December 9, 2025 at 4:37 PM
Our Researcher @mariodelr.bsky.social and Raquel Portela from @microbematos.bsky.social were invited by @healthnewspt.bsky.social to talk about their new collaboration project awarded by Early Career Research Award, 𝗜𝗻𝗳𝗲𝗰𝘁𝗼𝗙𝗶𝗧𝗧.
Read the full interview at: tinyurl.com/infectofitt
Read the full interview at: tinyurl.com/infectofitt
🚨🔬🤖🚀 #PhotoFiTT is out! With @guijacquemet.bsky.social's & @microbematos.bsky.social's labs, we launched a new phototoxicity measurement for live microscopy using cell clocks⏱️. By rockstars @mariodelr.bsky.social @gomez-mariscal.bsky.social et al! AI-powered + label-free
doi.org/10.1038/s414...
doi.org/10.1038/s414...
December 15, 2025 at 3:22 PM
🚨🔬🤖🚀 #PhotoFiTT is out! With @guijacquemet.bsky.social's & @microbematos.bsky.social's labs, we launched a new phototoxicity measurement for live microscopy using cell clocks⏱️. By rockstars @mariodelr.bsky.social @gomez-mariscal.bsky.social et al! AI-powered + label-free
doi.org/10.1038/s414...
doi.org/10.1038/s414...
Reposted by Ricardo Henriques
Latest from the lab "Filopodome proteomics identifies CCT8 as a MYO10 interactor critical for filopodia functions
"
www.biorxiv.org/content/10.6...
Work driven by @anagracanin.bsky.social
A great collaboration with @ivaskalab.bsky.social and @bengoult.bsky.social
"
www.biorxiv.org/content/10.6...
Work driven by @anagracanin.bsky.social
A great collaboration with @ivaskalab.bsky.social and @bengoult.bsky.social
Filopodome proteomics identifies CCT8 as a MYO10 interactor critical for filopodia functions
Cancer cells utilize filopodia to explore, adhere to, and invade their surrounding microenvironment, yet the protein networks that organize these protrusions remain incompletely defined. To uncover th...
www.biorxiv.org
December 6, 2025 at 6:48 AM
Latest from the lab "Filopodome proteomics identifies CCT8 as a MYO10 interactor critical for filopodia functions
"
www.biorxiv.org/content/10.6...
Work driven by @anagracanin.bsky.social
A great collaboration with @ivaskalab.bsky.social and @bengoult.bsky.social
"
www.biorxiv.org/content/10.6...
Work driven by @anagracanin.bsky.social
A great collaboration with @ivaskalab.bsky.social and @bengoult.bsky.social
Checkout @guijacquemet.bsky.social team amazing work ❤️
December 6, 2025 at 8:26 AM
Checkout @guijacquemet.bsky.social team amazing work ❤️
Reposted by Ricardo Henriques
December 6, 2025 at 6:52 AM
Reposted by Ricardo Henriques
🚀 New preprint out!
We introduce SMOLM-LFM: a simple, ratiometric, light-field–based method for 6D single-molecule orientation + localization, no polarization optics, no complex PSFs.
Fast.Robust.Large DoF.
A work done at @henriqueslab.bsky.social. In colaboration with the great L. AlemanCastaneda
We introduce SMOLM-LFM: a simple, ratiometric, light-field–based method for 6D single-molecule orientation + localization, no polarization optics, no complex PSFs.
Fast.Robust.Large DoF.
A work done at @henriqueslab.bsky.social. In colaboration with the great L. AlemanCastaneda
December 1, 2025 at 11:43 AM
🚀 New preprint out!
We introduce SMOLM-LFM: a simple, ratiometric, light-field–based method for 6D single-molecule orientation + localization, no polarization optics, no complex PSFs.
Fast.Robust.Large DoF.
A work done at @henriqueslab.bsky.social. In colaboration with the great L. AlemanCastaneda
We introduce SMOLM-LFM: a simple, ratiometric, light-field–based method for 6D single-molecule orientation + localization, no polarization optics, no complex PSFs.
Fast.Robust.Large DoF.
A work done at @henriqueslab.bsky.social. In colaboration with the great L. AlemanCastaneda
Wuhuuu, preprints using the #RxivMaker engine are popping 🍾
Also, the PDF or our preprint was created with Rχiv-Maker
@henriqueslab.bsky.social
rxiv-maker.henriqueslab.org
Paper: arxiv.org/html/2508.00...
@henriqueslab.bsky.social
rxiv-maker.henriqueslab.org
Paper: arxiv.org/html/2508.00...
November 27, 2025 at 8:54 AM
Wuhuuu, preprints using the #RxivMaker engine are popping 🍾
Reposted by Ricardo Henriques
Also, the PDF or our preprint was created with Rχiv-Maker
@henriqueslab.bsky.social
rxiv-maker.henriqueslab.org
Paper: arxiv.org/html/2508.00...
@henriqueslab.bsky.social
rxiv-maker.henriqueslab.org
Paper: arxiv.org/html/2508.00...
November 27, 2025 at 8:12 AM
Also, the PDF or our preprint was created with Rχiv-Maker
@henriqueslab.bsky.social
rxiv-maker.henriqueslab.org
Paper: arxiv.org/html/2508.00...
@henriqueslab.bsky.social
rxiv-maker.henriqueslab.org
Paper: arxiv.org/html/2508.00...