Max Renner
@maxrenner.bsky.social
PI at Umeå University and UCMR | Northern Sweden | Alum: @ox.ac.uk | Structural Virology | https://renner-lab.com/ | 🇸🇪 🦠🔬 🌱
Reposted by Max Renner
Reposted by Max Renner
Any researcher who didn’t particularly care for the smell of a email yesterday asking them to evaluate scientific papers for the purpose of creating a ‘novelty indicator’ will find it a rewarding read.
February 8, 2026 at 12:47 PM
Any researcher who didn’t particularly care for the smell of a email yesterday asking them to evaluate scientific papers for the purpose of creating a ‘novelty indicator’ will find it a rewarding read.
Reposted by Max Renner
Trapozoid cryo-FIB milling allows to prepare a lamella for dual-axis cryo-ET and assessment of different deep-learning missing-wedge restoration algorithms. rdcu.be/e2nXE
February 7, 2026 at 7:04 AM
Trapozoid cryo-FIB milling allows to prepare a lamella for dual-axis cryo-ET and assessment of different deep-learning missing-wedge restoration algorithms. rdcu.be/e2nXE
Reposted by Max Renner
Endogenous retroviruses synthesize heterologous chimeric RNAs to reinforce human early embryo development
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Endogenous retroviruses synthesize heterologous chimeric RNAs to reinforce human early embryo development
Zygotic genome activation (ZGA) failure leads to developmental arrest and poses a clinical challenge to women’s fertility. We observed that human embryos arresting at the eight-cell ZGA stage exhibite...
www.science.org
February 5, 2026 at 11:39 AM
Endogenous retroviruses synthesize heterologous chimeric RNAs to reinforce human early embryo development
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
What is very sad to me is that some people cannot tell how terribly this is "written".
February 5, 2026 at 8:10 AM
What is very sad to me is that some people cannot tell how terribly this is "written".
Reposted by Max Renner
We carried out a mechanistic study on how the PCBP1 protein destabilizes i-motifs. Understanding these interactions helps clarify fundamental mechanisms that control genome function.
Grateful for the long-term support we have received! @kawresearch.bsky.social @mbb-umu.bsky.social
rdcu.be/e2pIv
Grateful for the long-term support we have received! @kawresearch.bsky.social @mbb-umu.bsky.social
rdcu.be/e2pIv
February 5, 2026 at 5:10 AM
We carried out a mechanistic study on how the PCBP1 protein destabilizes i-motifs. Understanding these interactions helps clarify fundamental mechanisms that control genome function.
Grateful for the long-term support we have received! @kawresearch.bsky.social @mbb-umu.bsky.social
rdcu.be/e2pIv
Grateful for the long-term support we have received! @kawresearch.bsky.social @mbb-umu.bsky.social
rdcu.be/e2pIv
Reposted by Max Renner
My quote of the day
Nationalism is an infantile disease. It is the measles of mankind.
Albert Einstein
Nationalism is an infantile disease. It is the measles of mankind.
Albert Einstein
January 30, 2026 at 11:47 AM
My quote of the day
Nationalism is an infantile disease. It is the measles of mankind.
Albert Einstein
Nationalism is an infantile disease. It is the measles of mankind.
Albert Einstein
Reposted by Max Renner
Am I the only one increasingly annoyed by cryo-EM papers not showing *any* experimental density in figures? Sometimes not even in the supplementary material??
January 30, 2026 at 12:36 PM
Am I the only one increasingly annoyed by cryo-EM papers not showing *any* experimental density in figures? Sometimes not even in the supplementary material??
Reposted by Max Renner
The fusion of agentic AI and LLMs marks a new frontier in information warfare that threatens democracy
"Absent guardrails, LLM-driven swarms can transform sporadic mis- and disinformation into persistent, adaptive manipulation of democratic discourse"
www.science.org/doi/10.1126/...
"Absent guardrails, LLM-driven swarms can transform sporadic mis- and disinformation into persistent, adaptive manipulation of democratic discourse"
www.science.org/doi/10.1126/...
How malicious AI swarms can threaten democracy
The fusion of agentic AI and LLMs marks a new frontier in information warfare
www.science.org
January 28, 2026 at 5:33 PM
The fusion of agentic AI and LLMs marks a new frontier in information warfare that threatens democracy
"Absent guardrails, LLM-driven swarms can transform sporadic mis- and disinformation into persistent, adaptive manipulation of democratic discourse"
www.science.org/doi/10.1126/...
"Absent guardrails, LLM-driven swarms can transform sporadic mis- and disinformation into persistent, adaptive manipulation of democratic discourse"
www.science.org/doi/10.1126/...
Reposted by Max Renner
This horrific, and it contains the graphic original video. But if you can stomach it, you should watch it.
edition.cnn.com/2026/01/27/u...
edition.cnn.com/2026/01/27/u...
Exclusive: ‘Pink coat lady’ who recorded fatal encounter between federal officers and Alex Pretti speaks to Anderson Cooper | CNN
Anderson speaks with Stella Carlson, the witness who captured crucial video showing exactly what happened when Alex Pretti was shot and killed by DHS officers.
edition.cnn.com
January 28, 2026 at 9:29 AM
This horrific, and it contains the graphic original video. But if you can stomach it, you should watch it.
edition.cnn.com/2026/01/27/u...
edition.cnn.com/2026/01/27/u...
Reposted by Max Renner
Check out our new preprint! We uncover the full molecular mechanism of rotavirus membrane penetration and cytosolic escape using cryo-ET, live-cell imaging, and single-molecule assays. (1/3)
🔗 biorxiv.org/content/10.6...
🔗 biorxiv.org/content/10.6...
January 27, 2026 at 5:03 PM
Check out our new preprint! We uncover the full molecular mechanism of rotavirus membrane penetration and cytosolic escape using cryo-ET, live-cell imaging, and single-molecule assays. (1/3)
🔗 biorxiv.org/content/10.6...
🔗 biorxiv.org/content/10.6...
Reposted by Max Renner
Decoding influenza virus: From polymerase mechanisms to translational therapeutics
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
January 27, 2026 at 7:10 PM
Decoding influenza virus: From polymerase mechanisms to translational therapeutics
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Reposted by Max Renner
🦠 Nipah outbreak
Nipah virus outbreaks have high fatality rates, in the 40-70% range. The latest outbreak is in eastern India. Five cases are reported, and 100 people are under quarantine.
Several Asian countries are reported to be stepping up alertness.
1/2
Nipah virus outbreaks have high fatality rates, in the 40-70% range. The latest outbreak is in eastern India. Five cases are reported, and 100 people are under quarantine.
Several Asian countries are reported to be stepping up alertness.
1/2
Thailand Begins Airport Screening as Nipah Virus Outbreak Spreads in India
Thailand’s Ministry of Public Health has begun screening air passengers arriving from India for signs of Nipah virus infection, following reports of a cluster of cases in India’s eastern state...
slguardian.org
January 26, 2026 at 8:39 AM
🦠 Nipah outbreak
Nipah virus outbreaks have high fatality rates, in the 40-70% range. The latest outbreak is in eastern India. Five cases are reported, and 100 people are under quarantine.
Several Asian countries are reported to be stepping up alertness.
1/2
Nipah virus outbreaks have high fatality rates, in the 40-70% range. The latest outbreak is in eastern India. Five cases are reported, and 100 people are under quarantine.
Several Asian countries are reported to be stepping up alertness.
1/2
Reposted by Max Renner
"Today, lawless and masked thugs masquerading as law enforcement officers brutally killed another American citizen on the streets of Minneapolis without justification”
Minneapolis live: Man shot dead by federal agents in Minneapolis named as US citizen Alex Pretti
The shooting follows days of protests in the city over the Trump administration's immigration enforcement operation.
www.bbc.com
January 25, 2026 at 12:31 AM
"Today, lawless and masked thugs masquerading as law enforcement officers brutally killed another American citizen on the streets of Minneapolis without justification”
Reposted by Max Renner
A reminder to the news media: “conflicting accounts” is what you say BEFORE the incontrovertible video evidence appears. After that, your job is to ask why one side is lying, not to repeat the lie and pretend no one knows the truth.
January 25, 2026 at 12:28 PM
A reminder to the news media: “conflicting accounts” is what you say BEFORE the incontrovertible video evidence appears. After that, your job is to ask why one side is lying, not to repeat the lie and pretend no one knows the truth.
Reposted by Max Renner
Our paper is finally out!
I’m proud to share this collaborative work using FIB milling and cryo-electron tomography to study tick-borne flavivirus replication. Thanks to all co-authors and collaborators — great teamwork #CryoET #ElectronTomography #Virology #Flavivirus #Microscopy #StructuralBiology
I’m proud to share this collaborative work using FIB milling and cryo-electron tomography to study tick-borne flavivirus replication. Thanks to all co-authors and collaborators — great teamwork #CryoET #ElectronTomography #Virology #Flavivirus #Microscopy #StructuralBiology
I am super happy to share this paper in its final form. We used FIB milling to "dig in to" cell lines and mouse brains infected with tick-borne flaviviruses, followed by cryo-ET to study the virus replication. It's open access, so have a look!
#virology #teamtomo
www.nature.com/articles/s41...
#virology #teamtomo
www.nature.com/articles/s41...
Cryo-electron tomography reveals coupled flavivirus replication, budding and maturation - Nature Communications
In this study, Dahmane et al use a method called cryo-electron tomography to uncover new details of how tick-borne flaviviruses transform cells into virus factories.
www.nature.com
January 23, 2026 at 9:28 PM
Our paper is finally out!
I’m proud to share this collaborative work using FIB milling and cryo-electron tomography to study tick-borne flavivirus replication. Thanks to all co-authors and collaborators — great teamwork #CryoET #ElectronTomography #Virology #Flavivirus #Microscopy #StructuralBiology
I’m proud to share this collaborative work using FIB milling and cryo-electron tomography to study tick-borne flavivirus replication. Thanks to all co-authors and collaborators — great teamwork #CryoET #ElectronTomography #Virology #Flavivirus #Microscopy #StructuralBiology
Reposted by Max Renner
Defund ICE or shut the government down. This is the moderate position.
January 24, 2026 at 8:14 PM
Defund ICE or shut the government down. This is the moderate position.
Reposted by Max Renner
Cryo-EM structure reveals how influenza A virus NEP binds the viral polymerase at a regulatory hotspot, coordinating RNA synthesis and nuclear export. Fantastic collaboration with @loiccarrique.bsky.social and Jon Grimes. www.science.org/doi/10.1126/...
January 24, 2026 at 5:25 PM
Cryo-EM structure reveals how influenza A virus NEP binds the viral polymerase at a regulatory hotspot, coordinating RNA synthesis and nuclear export. Fantastic collaboration with @loiccarrique.bsky.social and Jon Grimes. www.science.org/doi/10.1126/...
Reposted by Max Renner
Beautiful work from @efodor.bsky.social and Jonathan Grimes' labs - the first full structure of the influenza A virus NEP protein, and a clear indication that its role in viral replication is more nuanced that first thought
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Regulatory hotspot on the influenza A virus polymerase revealed through the structure of the NEP-polymerase complex
Structural studies reveal how influenza virus switches between making new RNA genomes and exporting them from the host nucleus.
www.science.org
January 24, 2026 at 1:42 PM
Beautiful work from @efodor.bsky.social and Jonathan Grimes' labs - the first full structure of the influenza A virus NEP protein, and a clear indication that its role in viral replication is more nuanced that first thought
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Reposted by Max Renner
I am super happy to share this paper in its final form. We used FIB milling to "dig in to" cell lines and mouse brains infected with tick-borne flaviviruses, followed by cryo-ET to study the virus replication. It's open access, so have a look!
#virology #teamtomo
www.nature.com/articles/s41...
#virology #teamtomo
www.nature.com/articles/s41...
Cryo-electron tomography reveals coupled flavivirus replication, budding and maturation - Nature Communications
In this study, Dahmane et al use a method called cryo-electron tomography to uncover new details of how tick-borne flaviviruses transform cells into virus factories.
www.nature.com
January 23, 2026 at 4:47 PM
I am super happy to share this paper in its final form. We used FIB milling to "dig in to" cell lines and mouse brains infected with tick-borne flaviviruses, followed by cryo-ET to study the virus replication. It's open access, so have a look!
#virology #teamtomo
www.nature.com/articles/s41...
#virology #teamtomo
www.nature.com/articles/s41...
Reposted by Max Renner
We couldn't let World Handwriting Day go by without sharing Kathleen Lonsdale's penmanship ✍️
Lonsdale conducted pioneering research in X-ray crystallography and worked at the Ri. In 1929, she proved that the structure of benzene was flat—the chemical was also discovered here, by Michael Faraday.
Lonsdale conducted pioneering research in X-ray crystallography and worked at the Ri. In 1929, she proved that the structure of benzene was flat—the chemical was also discovered here, by Michael Faraday.
January 23, 2026 at 1:45 PM
We couldn't let World Handwriting Day go by without sharing Kathleen Lonsdale's penmanship ✍️
Lonsdale conducted pioneering research in X-ray crystallography and worked at the Ri. In 1929, she proved that the structure of benzene was flat—the chemical was also discovered here, by Michael Faraday.
Lonsdale conducted pioneering research in X-ray crystallography and worked at the Ri. In 1929, she proved that the structure of benzene was flat—the chemical was also discovered here, by Michael Faraday.
Reposted by Max Renner
Everyone bring out your microest violins 🎻
As a suggestion, you know what tool doesn't have a "consent data sharing" button? Your BRAIN 🙄🙄
www.nature.com/articles/d41...
As a suggestion, you know what tool doesn't have a "consent data sharing" button? Your BRAIN 🙄🙄
www.nature.com/articles/d41...
When two years of academic work vanished with a single click
After turning off ChatGPT’s ‘data consent’ option, Marcel Bucher lost the work behind grant applications, teaching materials and publication drafts. Here’s what happened next.
www.nature.com
January 23, 2026 at 8:40 AM
Everyone bring out your microest violins 🎻
As a suggestion, you know what tool doesn't have a "consent data sharing" button? Your BRAIN 🙄🙄
www.nature.com/articles/d41...
As a suggestion, you know what tool doesn't have a "consent data sharing" button? Your BRAIN 🙄🙄
www.nature.com/articles/d41...
Reposted by Max Renner
Excellent overview of the (mind-blowing) effects of the Shingles vaccine against dementia by @erictopol.bsky.social Ground Truth 🧪 "Two new studies add to a remarkable body of evidence for benefit" ⬇️
open.substack.com/pub/erictopo...
open.substack.com/pub/erictopo...
Spotlight on the Shingles Vaccine—Again!
Two new studies add to a remarkable body of evidence for benefit
open.substack.com
January 22, 2026 at 7:39 AM
Excellent overview of the (mind-blowing) effects of the Shingles vaccine against dementia by @erictopol.bsky.social Ground Truth 🧪 "Two new studies add to a remarkable body of evidence for benefit" ⬇️
open.substack.com/pub/erictopo...
open.substack.com/pub/erictopo...
Reposted by Max Renner
I never imagined I'd be writing this, but I am happy to share that, starting this June, I will be joining @cuanschutz.bsky.social @cu-bmg.bsky.social as an Assistant Professor.
January 21, 2026 at 7:13 AM
I never imagined I'd be writing this, but I am happy to share that, starting this June, I will be joining @cuanschutz.bsky.social @cu-bmg.bsky.social as an Assistant Professor.
Reposted by Max Renner
Beautiful infographic on a sad topic.
Trump has been in office for one year. We at @nature.com did a deep dive looking at the administration's disruption of science in numbers.
Take a look—the numbers are staggering. By me, @dangaristo.bsky.social, Jeff Tollefson, @kimay.bsky.social, & help from @noamross.net @scott-delaney.bsky.social
Take a look—the numbers are staggering. By me, @dangaristo.bsky.social, Jeff Tollefson, @kimay.bsky.social, & help from @noamross.net @scott-delaney.bsky.social
US science after a year of Trump: what has been lost and what remains
A series of graphics reveals how the Trump administration has sought historic cuts to science and the research workforce.
www.nature.com
January 21, 2026 at 4:37 PM
Beautiful infographic on a sad topic.