Max Renner
@maxrenner.bsky.social
PI at Umeå University and UCMR | Northern Sweden | Alum: @ox.ac.uk | Structural Virology | https://renner-lab.com/ | 🇸🇪 🦠🔬 🌱
Really exciting new research from our friendly colleagues down the hall 🤩🤩🤩
New preprint from the lab is out! 🥳
We systematically profiled all pairwise growth interactions between 36 representative human gut microbiome strains, and delved deeper into the molecular mechanisms behind specific growth interactions.
www.biorxiv.org/content/10.6...
👇
We systematically profiled all pairwise growth interactions between 36 representative human gut microbiome strains, and delved deeper into the molecular mechanisms behind specific growth interactions.
www.biorxiv.org/content/10.6...
👇
Systematic profiling of growth interactions in human gut microbiome species
Microbial interactions shape the composition and stability of the human gut microbiome. Yet, the molecular mechanisms underlying these relationships remain poorly understood. Here, we systematically p...
www.biorxiv.org
December 22, 2025 at 11:42 AM
Really exciting new research from our friendly colleagues down the hall 🤩🤩🤩
Reposted by Max Renner
An important question is, who is citing those papers?
Should it be considered misconduct to not even check whether what you are citing *exists*?
Should it be considered misconduct to not even check whether what you are citing *exists*?
December 20, 2025 at 4:15 PM
An important question is, who is citing those papers?
Should it be considered misconduct to not even check whether what you are citing *exists*?
Should it be considered misconduct to not even check whether what you are citing *exists*?
Reposted by Max Renner
🎄✨ Season’s Greetings from PDBe ✨🎄
The PDBe wishes you a very Merry Christmas and a Happy New Year. We are delighted to share our jointly designed EMDB/PDBe Christmas card with you. It has been a busy year, and we look forward to seeing you in the New Year.
The PDBe wishes you a very Merry Christmas and a Happy New Year. We are delighted to share our jointly designed EMDB/PDBe Christmas card with you. It has been a busy year, and we look forward to seeing you in the New Year.
December 18, 2025 at 2:12 PM
🎄✨ Season’s Greetings from PDBe ✨🎄
The PDBe wishes you a very Merry Christmas and a Happy New Year. We are delighted to share our jointly designed EMDB/PDBe Christmas card with you. It has been a busy year, and we look forward to seeing you in the New Year.
The PDBe wishes you a very Merry Christmas and a Happy New Year. We are delighted to share our jointly designed EMDB/PDBe Christmas card with you. It has been a busy year, and we look forward to seeing you in the New Year.
Same with universities, in my humble opinion...
The whole idea of responsible AI use is just companies encouraging people to use tools irresponsibly while telling people to use them responsibly.
December 17, 2025 at 8:38 AM
Same with universities, in my humble opinion...
Reposted by Max Renner
The whole idea of responsible AI use is just companies encouraging people to use tools irresponsibly while telling people to use them responsibly.
December 17, 2025 at 8:21 AM
The whole idea of responsible AI use is just companies encouraging people to use tools irresponsibly while telling people to use them responsibly.
Reposted by Max Renner
Vaults. They are cell biology's greatest puzzle! This preprint from Martin Beck's lab shows them docked on ER membranes with a ribosome inside. What on earth is going on there??
#CellBiology #WTFology
www.biorxiv.org/content/10.6...
#CellBiology #WTFology
www.biorxiv.org/content/10.6...
The vault associates with membranes in situ
The eukaryotic vault particle is a giant ribonucleoprotein complex that assembles into an iconic barrel-like cage. Its cellular function has remained elusive despite extensive characterization. Using ...
www.biorxiv.org
December 16, 2025 at 6:35 AM
Vaults. They are cell biology's greatest puzzle! This preprint from Martin Beck's lab shows them docked on ER membranes with a ribosome inside. What on earth is going on there??
#CellBiology #WTFology
www.biorxiv.org/content/10.6...
#CellBiology #WTFology
www.biorxiv.org/content/10.6...
Reposted by Max Renner
BBC News - Flu cases likely to 'spike' in coming weeks, warns health secretary - BBC News
www.bbc.co.uk/news/article...
www.bbc.co.uk/news/article...
Flu cases likely to 'spike' in coming weeks, warns health secretary
Neil Gray says the rise in cases is a challenge and urges anyone able to get vaccinated to do so.
www.bbc.co.uk
December 7, 2025 at 2:19 PM
BBC News - Flu cases likely to 'spike' in coming weeks, warns health secretary - BBC News
www.bbc.co.uk/news/article...
www.bbc.co.uk/news/article...
Reposted by Max Renner
Only a few days left to apply for this PhD opportunity in my lab! More details and how to apply at: www.findaphd.com/phds/project...
December 1, 2025 at 5:40 PM
Only a few days left to apply for this PhD opportunity in my lab! More details and how to apply at: www.findaphd.com/phds/project...
Reposted by Max Renner
Heute ist Welt-AIDS-Tag. HIV hat seinen Schrecken als tödliche Erkrankung verloren. Trotz des medizinischen Fortschritts steigen jedoch die Neuinfektionen, auch hier in Deutschland, und Infektionen werden spät diagnostiziert. (1/2)
www.tagesschau.de/wissen/gesun...
www.tagesschau.de/wissen/gesun...
Warum auch in Deutschland die HIV-Infektionszahlen steigen
Im vergangenen Jahr gab es in Deutschland mehr HIV-Neuinfektionen als im Jahr davor. Viele Infektionen werden erst im fortgeschrittenen Stadium erkannt - für Experten der Aidshilfe ein Alarmzeichen. V...
www.tagesschau.de
December 1, 2025 at 6:26 PM
Heute ist Welt-AIDS-Tag. HIV hat seinen Schrecken als tödliche Erkrankung verloren. Trotz des medizinischen Fortschritts steigen jedoch die Neuinfektionen, auch hier in Deutschland, und Infektionen werden spät diagnostiziert. (1/2)
www.tagesschau.de/wissen/gesun...
www.tagesschau.de/wissen/gesun...
Reposted by Max Renner
🚨👇One week left to apply for this fully-funded PhD project to study RNA-protein complexes regulating enterovirus genome replication:
www.findaphd.com/phds/project...
www.findaphd.com/phds/project...
MRC DiMeN Doctoral Training Partnership: Understanding molecular mechanisms of protein-primed genome replication in enteroviruses at University of York on FindAPhD.com
PhD Project - MRC DiMeN Doctoral Training Partnership: Understanding molecular mechanisms of protein-primed genome replication in enteroviruses at University of York, listed on FindAPhD.com
www.findaphd.com
November 28, 2025 at 12:41 PM
🚨👇One week left to apply for this fully-funded PhD project to study RNA-protein complexes regulating enterovirus genome replication:
www.findaphd.com/phds/project...
www.findaphd.com/phds/project...
Reposted by Max Renner
What do you think?
Real SDS-PAGE gel or AI-generated ?
Real SDS-PAGE gel or AI-generated ?
November 26, 2025 at 7:47 AM
What do you think?
Real SDS-PAGE gel or AI-generated ?
Real SDS-PAGE gel or AI-generated ?
Reposted by Max Renner
It’s been a while since I put together the Structural Virology starter pack, and I’m sure some new folks have joined Bluesky since then. There’s still plenty of space to fill, so if you’d like to be added to the list just let me know.
#virology #cryoEM
go.bsky.app/Qxv95BL
#virology #cryoEM
go.bsky.app/Qxv95BL
November 25, 2025 at 9:46 AM
It’s been a while since I put together the Structural Virology starter pack, and I’m sure some new folks have joined Bluesky since then. There’s still plenty of space to fill, so if you’d like to be added to the list just let me know.
#virology #cryoEM
go.bsky.app/Qxv95BL
#virology #cryoEM
go.bsky.app/Qxv95BL
Reposted by Max Renner
Scientific journals: we don’t want you using generative AI because it makes shit up.
Same journal: here is an AI summary or evaluation of this paper. This might be more useful than the actual abstract or paper that the authors freaking wrote
Same journal: AI cover art which makes no sense? Oooh!
Same journal: here is an AI summary or evaluation of this paper. This might be more useful than the actual abstract or paper that the authors freaking wrote
Same journal: AI cover art which makes no sense? Oooh!
November 23, 2025 at 1:51 AM
Scientific journals: we don’t want you using generative AI because it makes shit up.
Same journal: here is an AI summary or evaluation of this paper. This might be more useful than the actual abstract or paper that the authors freaking wrote
Same journal: AI cover art which makes no sense? Oooh!
Same journal: here is an AI summary or evaluation of this paper. This might be more useful than the actual abstract or paper that the authors freaking wrote
Same journal: AI cover art which makes no sense? Oooh!
Reposted by Max Renner
Our latest T7SS study is now out in Science Advances!
We solved the cryoEM structure of the T7SSb core unit (T7bCU) composed of YukB, YukC, and YukD from Bacillus subtilis, revealing how these components assemble within the secretion machinery.
www.science.org/doi/10.1126/...
We solved the cryoEM structure of the T7SSb core unit (T7bCU) composed of YukB, YukC, and YukD from Bacillus subtilis, revealing how these components assemble within the secretion machinery.
www.science.org/doi/10.1126/...
A ubiquitin-like protein controls assembly of a bacterial type VIIb secretion system
Cryo-EM structure reveals how a ubiquitin-like protein orchestrates assembly of a bacterial weapon system.
www.science.org
November 21, 2025 at 7:05 PM
Our latest T7SS study is now out in Science Advances!
We solved the cryoEM structure of the T7SSb core unit (T7bCU) composed of YukB, YukC, and YukD from Bacillus subtilis, revealing how these components assemble within the secretion machinery.
www.science.org/doi/10.1126/...
We solved the cryoEM structure of the T7SSb core unit (T7bCU) composed of YukB, YukC, and YukD from Bacillus subtilis, revealing how these components assemble within the secretion machinery.
www.science.org/doi/10.1126/...
Reposted by Max Renner
Imagine we would have a pan-herpesvirus vaccine. How would it improve human health? Based on the last few years of data, I am thinking it would change a lot.
November 20, 2025 at 6:19 PM
Imagine we would have a pan-herpesvirus vaccine. How would it improve human health? Based on the last few years of data, I am thinking it would change a lot.
Reposted by Max Renner
🧪For anyone interested in EBV in autoimmunity, I strongly urge you to read this incredible study by @shady-myounis.bsky.social, Bill Robinson, and @tobiaslanz.bsky.social. It is not only a scientific tour de force, it has a deeply provocative discussion that everyone in the field should consider 1/
Epstein-Barr virus reprograms autoreactive B cells as antigen-presenting cells in systemic lupus erythematosus
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Epstein-Barr virus reprograms autoreactive B cells as antigen-presenting cells in systemic lupus erythematosus
Epstein-Barr virus reprograms autoreactive B cells as antigen-presenting cells to promote pathogenic antinuclear T and B cell responses in lupus.
www.science.org
November 19, 2025 at 5:24 PM
🧪For anyone interested in EBV in autoimmunity, I strongly urge you to read this incredible study by @shady-myounis.bsky.social, Bill Robinson, and @tobiaslanz.bsky.social. It is not only a scientific tour de force, it has a deeply provocative discussion that everyone in the field should consider 1/
Reposted by Max Renner
Tired of knowing what you are looking for in your tomograms?
Why not try bluesky-less Frosina's new self-supervised algorithm for semantic segmentation and particle picking for #teamtomo (includes a new denoiser without the need for odd/even tomos)
Code is on GitHub if you want to try it out
Why not try bluesky-less Frosina's new self-supervised algorithm for semantic segmentation and particle picking for #teamtomo (includes a new denoiser without the need for odd/even tomos)
Code is on GitHub if you want to try it out
November 19, 2025 at 2:04 PM
Tired of knowing what you are looking for in your tomograms?
Why not try bluesky-less Frosina's new self-supervised algorithm for semantic segmentation and particle picking for #teamtomo (includes a new denoiser without the need for odd/even tomos)
Code is on GitHub if you want to try it out
Why not try bluesky-less Frosina's new self-supervised algorithm for semantic segmentation and particle picking for #teamtomo (includes a new denoiser without the need for odd/even tomos)
Code is on GitHub if you want to try it out
Reposted by Max Renner
This is misinformation by default, so if you're a journal and you use AI slop for your cover or your announcements, you're not scientific in any way and should be shamed mercilessly 🧪
November 18, 2025 at 2:07 PM
This is misinformation by default, so if you're a journal and you use AI slop for your cover or your announcements, you're not scientific in any way and should be shamed mercilessly 🧪
Truer words have not been spoken
if microsoft just made outlook search not suck they'd see triple the productivity gains of any AI integration
November 14, 2025 at 7:34 AM
Truer words have not been spoken
Reposted by Max Renner
We’re live!
The Department of Medical Biochemistry & Biophysics at @umeauniversitet.bsky.social explores life at the molecular level: infection and structural biology, gene expression, mitochondria, neurodegeneration & biophysics for climate change.
Follow for updates & collaboration!
#Biochemistry
The Department of Medical Biochemistry & Biophysics at @umeauniversitet.bsky.social explores life at the molecular level: infection and structural biology, gene expression, mitochondria, neurodegeneration & biophysics for climate change.
Follow for updates & collaboration!
#Biochemistry
November 13, 2025 at 9:59 AM
We’re live!
The Department of Medical Biochemistry & Biophysics at @umeauniversitet.bsky.social explores life at the molecular level: infection and structural biology, gene expression, mitochondria, neurodegeneration & biophysics for climate change.
Follow for updates & collaboration!
#Biochemistry
The Department of Medical Biochemistry & Biophysics at @umeauniversitet.bsky.social explores life at the molecular level: infection and structural biology, gene expression, mitochondria, neurodegeneration & biophysics for climate change.
Follow for updates & collaboration!
#Biochemistry
Reposted by Max Renner
Withdrawing life-saving aid from developing countries and then demanding economically favourable conditions for restoring it would be bad enough, but the conditions and the approach also directly undermine international co-operation against future pandemics in favour of short-term national gain
I don't like the sound of this: www.theguardian.com/global-devel...
US to demand countries share data on ‘pathogens with epidemic potential’ in return for health aid
Draft template seen by the Guardian has no reference to countries receiving benefits for sharing information, such as guaranteed access to medicines developed as a result
www.theguardian.com
November 11, 2025 at 7:53 PM
Withdrawing life-saving aid from developing countries and then demanding economically favourable conditions for restoring it would be bad enough, but the conditions and the approach also directly undermine international co-operation against future pandemics in favour of short-term national gain
Reposted by Max Renner
I am excited to share our new preprint on our structural and biochemical analyses of human methionine synthase (MTR). This was the hard work of Douglas Ferreira who carried out this research as a significant part of his PhD. #CryoEM www.biorxiv.org/content/10.1...
Structural insights into cobalamin loading and reactivation of human methionine synthase
Human methionine synthase (MTR) is an essential enzyme of one carbon metabolism. Consisting of a catalytic N-half and a cobalamin binding C-half, MTR utilises this intricate organometallic cofactor in...
www.biorxiv.org
November 11, 2025 at 12:48 PM
I am excited to share our new preprint on our structural and biochemical analyses of human methionine synthase (MTR). This was the hard work of Douglas Ferreira who carried out this research as a significant part of his PhD. #CryoEM www.biorxiv.org/content/10.1...
Reposted by Max Renner
Some still praise James Watson despite his racism. Same with colleagues who won’t condemn Elon Musk’s politics, hiding behind “scientists shouldn’t mix science and politics.”
November 8, 2025 at 12:36 PM
Some still praise James Watson despite his racism. Same with colleagues who won’t condemn Elon Musk’s politics, hiding behind “scientists shouldn’t mix science and politics.”
Reposted by Max Renner
November 7th, 2000.
November 7, 2025 at 2:58 PM
November 7th, 2000.
Reposted by Max Renner
Very happy to share our work on the Langya henipavirus nucleoprotein with everyone! 🥳
Check out the preprint to find more about how a serendipitous finding led us to this amazing story!
Check out the preprint to find more about how a serendipitous finding led us to this amazing story!
Our new preprint is out 🥳🥳🥳
Henipaviruses, like Nipah and Hendra, package their genomes inside helical shells built by thousands of nucleoproteins. These nucleocapsids are essential to protect the viral RNA, but how do they ever let the polymerase in to read the sequence?
👇
Henipaviruses, like Nipah and Hendra, package their genomes inside helical shells built by thousands of nucleoproteins. These nucleocapsids are essential to protect the viral RNA, but how do they ever let the polymerase in to read the sequence?
👇
November 3, 2025 at 3:21 PM
Very happy to share our work on the Langya henipavirus nucleoprotein with everyone! 🥳
Check out the preprint to find more about how a serendipitous finding led us to this amazing story!
Check out the preprint to find more about how a serendipitous finding led us to this amazing story!