Max Renner
@maxrenner.bsky.social
PI at Umeå University and UCMR | Northern Sweden | Alum: @ox.ac.uk | Structural Virology | https://renner-lab.com/ | 🇸🇪 🦠🔬 🌱
Thanks Gytis, interesting 🤔! I don't think our structures explicitly explain this but we will give it some thought in light of the broader structural data available now.
November 3, 2025 at 1:41 PM
Thanks Gytis, interesting 🤔! I don't think our structures explicitly explain this but we will give it some thought in light of the broader structural data available now.
So proud of PhD student @rupeshjayachandran.bsky.social and postdoc Erwan Quignon for leading this research.
You can find the preprint here:
🔗 www.biorxiv.org/content/10.1...
You can find the preprint here:
🔗 www.biorxiv.org/content/10.1...
Open and closed forms of assembled henipavirus nucleoprotein suggest structural basis of genome access
Henipaviruses, such as Nipah virus, can cause deadly illness and constitute WHO blueprint priorities due to their pandemic potential. Their genomes are packaged within a nucleocapsid consisting of vir...
www.biorxiv.org
November 3, 2025 at 12:31 PM
So proud of PhD student @rupeshjayachandran.bsky.social and postdoc Erwan Quignon for leading this research.
You can find the preprint here:
🔗 www.biorxiv.org/content/10.1...
You can find the preprint here:
🔗 www.biorxiv.org/content/10.1...
In our biorxiv preprint, we present cryo-EM structures of assembled nucleoproteins from Langya henipavirus in both RNA-bound and RNA-free forms.
We see open and closed states and suggest opening of the assembled nucleocapsid protomers could give the polymerase fleeting access to the genome.
We see open and closed states and suggest opening of the assembled nucleocapsid protomers could give the polymerase fleeting access to the genome.
November 3, 2025 at 12:30 PM
In our biorxiv preprint, we present cryo-EM structures of assembled nucleoproteins from Langya henipavirus in both RNA-bound and RNA-free forms.
We see open and closed states and suggest opening of the assembled nucleocapsid protomers could give the polymerase fleeting access to the genome.
We see open and closed states and suggest opening of the assembled nucleocapsid protomers could give the polymerase fleeting access to the genome.
October 22, 2025 at 9:07 AM