Kristen Naegle (she/her)
@knaegle.bsky.social
Associate Professor of Biomedical Engineering, Computational and Systems biology research of how cells use biochemical networks to make decisions.
Reposted by Kristen Naegle (she/her)
Marching and protesting is great but real action is even better. If you can afford it, find and donate to a local food pantry in your area. The families that depend on SNAP benefits could really use the support over coming weeks to months.❤️🫂
give.feedingamerica.org/SnP--N8F9EuA...
give.feedingamerica.org/SnP--N8F9EuA...
Join me in ending hunger
I just donated to @FeedingAmerica to help make sure families and kids have the meals they need!
http://feeding.am/givemeals
give.feedingamerica.org
October 23, 2025 at 11:43 AM
Marching and protesting is great but real action is even better. If you can afford it, find and donate to a local food pantry in your area. The families that depend on SNAP benefits could really use the support over coming weeks to months.❤️🫂
give.feedingamerica.org/SnP--N8F9EuA...
give.feedingamerica.org/SnP--N8F9EuA...
Reposted by Kristen Naegle (she/her)
Hey guys... this is serious please go and opt out NOW!
August 12, 2025 at 8:00 PM
Hey guys... this is serious please go and opt out NOW!
Reposted by Kristen Naegle (she/her)
These are the most challenging times for early-career scientists and engineers.
My team is doing its bit to help by maintaining and even expanding our database of funding opportunities for early-career researchers.
We found 437 of them.
Download it freely here: research.jhu.edu/rdt/funding-...
My team is doing its bit to help by maintaining and even expanding our database of funding opportunities for early-career researchers.
We found 437 of them.
Download it freely here: research.jhu.edu/rdt/funding-...
August 11, 2025 at 11:54 AM
These are the most challenging times for early-career scientists and engineers.
My team is doing its bit to help by maintaining and even expanding our database of funding opportunities for early-career researchers.
We found 437 of them.
Download it freely here: research.jhu.edu/rdt/funding-...
My team is doing its bit to help by maintaining and even expanding our database of funding opportunities for early-career researchers.
We found 437 of them.
Download it freely here: research.jhu.edu/rdt/funding-...
Please give feedback. I know I'm considering the new NIH mandate that open access has to be immediately available, meaning that grantees are footing open access bills at journals to meet the mandate. That can mean $5-$12K a paper of taxpayers money.
NIH wants to hear from you. No really.
Request for Information on Maximizing Research Funds by Limiting Allowable Publishing Costs
grants.nih.gov/grants/guide...
Request for Information on Maximizing Research Funds by Limiting Allowable Publishing Costs
grants.nih.gov/grants/guide...
NOT-OD-25-138: Request for Information on Maximizing Research Funds by Limiting Allowable Publishing Costs
NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Request for Information on Maximizing Research Funds by Limiting Allowable Publishing Costs NOT-OD-25-138. NIH
grants.nih.gov
July 31, 2025 at 12:27 PM
Please give feedback. I know I'm considering the new NIH mandate that open access has to be immediately available, meaning that grantees are footing open access bills at journals to meet the mandate. That can mean $5-$12K a paper of taxpayers money.
No, no, this is all wrong. The quote is actually supposed to be "let them eat cake".
Apropos of nothing, Happy Bastille day to all those who celebrate.
Apropos of nothing, Happy Bastille day to all those who celebrate.
“Don’t eat carrot cake. Eat real food,” said Medicaid and Medicare Administrator Mehmet Oz to people who are concerned about Medicaid cuts, after bringing Fox host Stuart Varney a carrot cake as a gift.
Dr. Oz Tells Americans Who Are Concerned About Medicaid Cuts to Eat Less Cake
Millions of Americans will lose health care coverage due to the Medicaid cuts in Trump’s “Big Beautiful Bill.”…
buff.ly
July 14, 2025 at 10:32 PM
No, no, this is all wrong. The quote is actually supposed to be "let them eat cake".
Apropos of nothing, Happy Bastille day to all those who celebrate.
Apropos of nothing, Happy Bastille day to all those who celebrate.
Reposted by Kristen Naegle (she/her)
There are currently more kids in Texas with measles than there are transgender collegiate athletes in all of America.
Guess which one they want you to focus on.
Guess which one they want you to focus on.
July 12, 2025 at 4:00 PM
There are currently more kids in Texas with measles than there are transgender collegiate athletes in all of America.
Guess which one they want you to focus on.
Guess which one they want you to focus on.
$123,536,510 of federally appropriated funding has been stolen from Virginia schools
The Trump administration is currently holding hostage nearly $7B in federal funding for K-12 schools--funding that was supposed to be distributed yesterday.
They've stolen $80M from Wisconsin students and teachers alone. How much have they stolen from your state?
www.edweek.org/policy-polit...
They've stolen $80M from Wisconsin students and teachers alone. How much have they stolen from your state?
www.edweek.org/policy-polit...
See How Much School Funding Trump Is Holding Back From Your State
The administration is holding back nearly $7 billion for English learners, after-school programs, professional development, and more.
www.edweek.org
July 2, 2025 at 2:23 PM
$123,536,510 of federally appropriated funding has been stolen from Virginia schools
Reposted by Kristen Naegle (she/her)
On just one Friday the Supreme Court brought my citizenship into question and the Trump administration gutted my employer and possibly threaten my career. I could only write about one of those things. newrepublic.com/article/1973...
UVA President James Ryan Caved to MAGA—and They Forced Him Out Anyway
Ryan had not fought Trump on DEI and other matters. His forced ouster proves that no capitulation is enough.
newrepublic.com
June 28, 2025 at 1:24 PM
On just one Friday the Supreme Court brought my citizenship into question and the Trump administration gutted my employer and possibly threaten my career. I could only write about one of those things. newrepublic.com/article/1973...
Reposted by Kristen Naegle (she/her)
In the fallout of James Ryan resigning from UVA, @sivav.bsky.social provides a clear argument of what higher ed is facing & why capitulation will not save you. newrepublic.com/article/1973...
June 28, 2025 at 11:18 AM
In the fallout of James Ryan resigning from UVA, @sivav.bsky.social provides a clear argument of what higher ed is facing & why capitulation will not save you. newrepublic.com/article/1973...
Reposted by Kristen Naegle (she/her)
thank you, @sivav.bsky.social, for putting a lot of what I’m furious about in plain language. newrepublic.com/article/1973...
UVA President James Ryan Caved to MAGA—and They Forced Him Out Anyway
Ryan had not fought Trump on DEI and other matters. His forced ouster proves that no capitulation is enough.
newrepublic.com
June 28, 2025 at 9:48 AM
thank you, @sivav.bsky.social, for putting a lot of what I’m furious about in plain language. newrepublic.com/article/1973...
Reposted by Kristen Naegle (she/her)
PLEASE SHARE 🧪‼️
Vaccination schedules on the CDC website have already started changing under RFK Jr.
Scientific American has published a guide to the EVIDENCE-BASED vaccine recommendations in place BEFORE ACIP members were removed by the administration.
www.scientificamerican.com/article/see-...
Vaccination schedules on the CDC website have already started changing under RFK Jr.
Scientific American has published a guide to the EVIDENCE-BASED vaccine recommendations in place BEFORE ACIP members were removed by the administration.
www.scientificamerican.com/article/see-...
Here’s Your Cheat Sheet for Vaccine Recommendations Backed by Science
These graphics will guide you through science-based vaccine guidelines for children and adults
www.scientificamerican.com
June 25, 2025 at 4:00 PM
PLEASE SHARE 🧪‼️
Vaccination schedules on the CDC website have already started changing under RFK Jr.
Scientific American has published a guide to the EVIDENCE-BASED vaccine recommendations in place BEFORE ACIP members were removed by the administration.
www.scientificamerican.com/article/see-...
Vaccination schedules on the CDC website have already started changing under RFK Jr.
Scientific American has published a guide to the EVIDENCE-BASED vaccine recommendations in place BEFORE ACIP members were removed by the administration.
www.scientificamerican.com/article/see-...
So happy to see this work is out and I hope it helps people find their best lab fit!
From @knaegle.bsky.social & colleagues in @plos.org #Computational #Biology | Ten simple rules for effectively assessing lab environments | I like all of the rules, but particularly Rule 10: Know the emergency exits | #Education #PLOSCBTSR 🧬 🖥️ 🧪 🔓
⬇️
journals.plos.org/ploscompbiol...
⬇️
journals.plos.org/ploscompbiol...
Ten simple rules for effectively assessing lab environments
journals.plos.org
June 25, 2025 at 7:04 PM
So happy to see this work is out and I hope it helps people find their best lab fit!
Reposted by Kristen Naegle (she/her)
Charlottesville is turning into an e-bike city!
Great article from @nathanalderman.bsky.social on the @cvillecityhall.bsky.social e-bike voucher program, which is one piece of the city’s efforts to create a better transportation system.
c-ville.com/citys-e-bike...
Great article from @nathanalderman.bsky.social on the @cvillecityhall.bsky.social e-bike voucher program, which is one piece of the city’s efforts to create a better transportation system.
c-ville.com/citys-e-bike...
City’s e-bike voucher program provides some extra pedal power - C-VILLE Weekly
UVA doctoral candidate T.C.A. Achintya needed a better way to get around. A new program from the City of Charlottesville made it happen. “I had contemplated buying a regular bike, since I don’t own a ...
c-ville.com
June 21, 2025 at 10:49 AM
Charlottesville is turning into an e-bike city!
Great article from @nathanalderman.bsky.social on the @cvillecityhall.bsky.social e-bike voucher program, which is one piece of the city’s efforts to create a better transportation system.
c-ville.com/citys-e-bike...
Great article from @nathanalderman.bsky.social on the @cvillecityhall.bsky.social e-bike voucher program, which is one piece of the city’s efforts to create a better transportation system.
c-ville.com/citys-e-bike...
Reposted by Kristen Naegle (she/her)
Almost all Nobel Prizes are awarded for work that is exploratory, or absolutely basic science with no obvious commercial or medical benefit.
You cannot predict where advancements come from, so you have to invest in science and scientists.
Targeted (corporate) science investment will never do this.
You cannot predict where advancements come from, so you have to invest in science and scientists.
Targeted (corporate) science investment will never do this.
Reminder: Nobel-prize winning PCR (1983), used in basically all genetic tech today, was only possible because of extremophile bacterium discovered in 1964 in Yellowstone funded by a small ~$80k NSF grant with no obvious application at the time. #science 🧪
www.richmondscientific.com/how-a-discov...
www.richmondscientific.com/how-a-discov...
How a discovery in Yellowstone National Park led to the development of PCR - Richmond Scientific
A discovery in Yellowstone National Park led to the development of PCR, the gold-standard COVID-19 tests used to fight the global pandemic.
www.richmondscientific.com
June 8, 2025 at 10:26 PM
Almost all Nobel Prizes are awarded for work that is exploratory, or absolutely basic science with no obvious commercial or medical benefit.
You cannot predict where advancements come from, so you have to invest in science and scientists.
Targeted (corporate) science investment will never do this.
You cannot predict where advancements come from, so you have to invest in science and scientists.
Targeted (corporate) science investment will never do this.
Reposted by Kristen Naegle (she/her)
Grant freezes versus terminations feel different, but they have the same practical effect.
We should start treating freezes as terminations, both of which can be undone by HHS / NIH whenever they want—or by court order if they refuse. They’re all illegal.
We should start treating freezes as terminations, both of which can be undone by HHS / NIH whenever they want—or by court order if they refuse. They’re all illegal.
Northwestern has not received any NIH funds since March. No written communication about why or what can be done. Thank you Ben Singer for raising awareness at #ATS2025
May 19, 2025 at 11:40 AM
Grant freezes versus terminations feel different, but they have the same practical effect.
We should start treating freezes as terminations, both of which can be undone by HHS / NIH whenever they want—or by court order if they refuse. They’re all illegal.
We should start treating freezes as terminations, both of which can be undone by HHS / NIH whenever they want—or by court order if they refuse. They’re all illegal.
Reposted by Kristen Naegle (she/her)
say it again:
4 million people work in higher ed, the largest employer in 10 states, second largest employer in 10 more, and in 60 of the 100 biggest cities
ROI for NIH and NSF for local economies is conservatively 4x, often close to 10x
demolishing higher education is economic sabotage
4 million people work in higher ed, the largest employer in 10 states, second largest employer in 10 more, and in 60 of the 100 biggest cities
ROI for NIH and NSF for local economies is conservatively 4x, often close to 10x
demolishing higher education is economic sabotage
There is a false dichotomy drawn between "the ivory tower" and "the real world," and I'm here to report that in a post-industrial society, your real-world economy absolutely hinges on the university.
University towns are factory towns. Universities drive economic activity, not the other way around.
University towns are factory towns. Universities drive economic activity, not the other way around.
A must read
May 18, 2025 at 1:45 PM
say it again:
4 million people work in higher ed, the largest employer in 10 states, second largest employer in 10 more, and in 60 of the 100 biggest cities
ROI for NIH and NSF for local economies is conservatively 4x, often close to 10x
demolishing higher education is economic sabotage
4 million people work in higher ed, the largest employer in 10 states, second largest employer in 10 more, and in 60 of the 100 biggest cities
ROI for NIH and NSF for local economies is conservatively 4x, often close to 10x
demolishing higher education is economic sabotage
This is devastating for American science, health, technology, and the economy.
Yesterday, the NIH R35 “Outstanding Investigator” grant to fund scientists in my lab studying antibiotic resistance was terminated for reasons not related to the content of the science, or any actions taken by me or members of my lab
May 14, 2025 at 11:33 AM
This is devastating for American science, health, technology, and the economy.
Reposted by Kristen Naegle (she/her)
We updated the reporting form today to clarify that we're also collecting info on "stop-work orders, unexpected non-renewals, or effective termination through updated notice of award." grant-watch.us/submit-nih.h...
If you're at one of the targeted institutions and have an active NIH grant you might want to check ERA Commons immediately for an "updated" NoA
May 13, 2025 at 2:40 AM
We updated the reporting form today to clarify that we're also collecting info on "stop-work orders, unexpected non-renewals, or effective termination through updated notice of award." grant-watch.us/submit-nih.h...
Reposted by Kristen Naegle (she/her)
We’ve become so desensitized to corruption that the Attorney General who spent years lobbying on behalf of Qatar approved a private jet gift from Qatar and it’s not even in the top 10 scandals of the week.
May 11, 2025 at 7:07 PM
We’ve become so desensitized to corruption that the Attorney General who spent years lobbying on behalf of Qatar approved a private jet gift from Qatar and it’s not even in the top 10 scandals of the week.
Reposted by Kristen Naegle (she/her)
“The results revealed that researchers who received renewals without a funding gap were less likely to switch research topics and investigate a wide array of subjects than were those in the control group, and they produced papers featuring newer or more unconventional combinations of ideas”
Innovation takes time
US scientists who received renewals from the NIH over the past four decades produced more novel research than those who didn’t
https://go.nature.com/44s6cc5
US scientists who received renewals from the NIH over the past four decades produced more novel research than those who didn’t
https://go.nature.com/44s6cc5
Renewal of NIH grants linked to more innovative results, study finds
Nature - Survey of hundreds of scientists’ work suggests that cutting off funding disrupts focus and reduces the novelty of research.
go.nature.com
May 10, 2025 at 3:20 PM
“The results revealed that researchers who received renewals without a funding gap were less likely to switch research topics and investigate a wide array of subjects than were those in the control group, and they produced papers featuring newer or more unconventional combinations of ideas”
I heard the new pope is a math major. So that means he understands both sin and sin^-1 right?
May 8, 2025 at 8:14 PM
I heard the new pope is a math major. So that means he understands both sin and sin^-1 right?
It has been scientifically shown that all dogs can engage an anchor mode by which their effective weight is quadruple their normal weight.
April 30, 2025 at 4:08 PM
It has been scientifically shown that all dogs can engage an anchor mode by which their effective weight is quadruple their normal weight.
For Charlottesville peeps, MAGA-endorsing businesses include Charlottesville Tire and Auto, First Free Coffee, The Gym, Start 2 Finish nutrition, and several contractors and photographers.
NEW: PublicSquare, a website that lets you search for businesses in your community that explicitly want you to know they endorse Trump/MAGA values, is backfiring as people use it to boycott those businesses. www.huffpost.com/entry/public...
Website For MAGA-Friendly Businesses Backfires As People Use It For Boycotts
Social media posts about PublicSquare have gone viral as Trump critics use it to find companies not to support – the opposite of what the site was set up for.
www.huffpost.com
April 26, 2025 at 3:11 PM
For Charlottesville peeps, MAGA-endorsing businesses include Charlottesville Tire and Auto, First Free Coffee, The Gym, Start 2 Finish nutrition, and several contractors and photographers.
Reposted by Kristen Naegle (she/her)
NEW: PublicSquare, a website that lets you search for businesses in your community that explicitly want you to know they endorse Trump/MAGA values, is backfiring as people use it to boycott those businesses. www.huffpost.com/entry/public...
Website For MAGA-Friendly Businesses Backfires As People Use It For Boycotts
Social media posts about PublicSquare have gone viral as Trump critics use it to find companies not to support – the opposite of what the site was set up for.
www.huffpost.com
April 26, 2025 at 1:39 PM
NEW: PublicSquare, a website that lets you search for businesses in your community that explicitly want you to know they endorse Trump/MAGA values, is backfiring as people use it to boycott those businesses. www.huffpost.com/entry/public...
Reposted by Kristen Naegle (she/her)
Update: I have been able to confirm grants worth ~$6M were terminated but think the total may be as high as $94M.
If you or your colleagues got a termination letter, considering responding to the form. You can do so anonymously.
If you or your colleagues got a termination letter, considering responding to the form. You can do so anonymously.
Dear US-based misinfo/disinfo research community: I am looking to write about the impact of Friday night's NSF decision.
I understand that this is a stressful moment, but also believe it is worth giving the public an understanding of what's at stake.
docs.google.com/forms/d/1MQP...
I understand that this is a stressful moment, but also believe it is worth giving the public an understanding of what's at stake.
docs.google.com/forms/d/1MQP...
NSF misinfo/disinfo grant survey
This survey is run by Alexios Mantzarlis (mantzarlis.com) for his newsletter Faked Up (fakedup.org). The purpose is to understand the scale of the recent NSF decision (nsf.gov/updates-on-priorities) t...
docs.google.com
April 21, 2025 at 6:28 PM
Update: I have been able to confirm grants worth ~$6M were terminated but think the total may be as high as $94M.
If you or your colleagues got a termination letter, considering responding to the form. You can do so anonymously.
If you or your colleagues got a termination letter, considering responding to the form. You can do so anonymously.