BF Francis Ouellette
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bffo.bsky.social
BF Francis Ouellette
@bffo.bsky.social
3.1K followers 4.8K following 390 posts
Bioinformatics 🧬🖥️🧪
#PLOS Comp Biol Education Sect. Editor;
#DATABASE OUP Associate Editor;
#OpenScience #OpenAccess #OpenData;
friend of @jxtxfoundation.bsky.social,
@abinstitute.bsky.social
- I am 🇨🇦
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bffo.bsky.social
BF Francis Ouellette @bffo.bsky.social · Nov 29
Be Open so the world can see how great you are!

#OpenScience
#OpenAccess
#OpenData
#OpenSource
#OpenEducationalResources
bffo.bsky.social
From Lincoln Stein & colleagues in @biorxivpreprint.bsky.social | React-to-Me: A Conversational Interface for Interactive Exploration of the Reactome Pathway Knowledgebase | #Bioinformatics #Database #Pathways #Reactome #Proteomics 🧬 🖥️ 🧪 🔓
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www.biorxiv.org/content/10.6...
React-to-Me: A Conversational Interface for Interactive Exploration of the Reactome Pathway Knowledgebase
The Reactome Pathway Knowledgebase ([www.reactome.org][1]) provides expert-curated information on human biological pathways, molecular interactions, and disease mechanisms. However, its complex data m...
www.biorxiv.org
January 3, 2026 at 9:16 PM
bffo.bsky.social
From the @narjournal.bsky.social #NARDatabaseIssue | CircTarget: a comprehensive database of circRNA--target RNA interactions across multiple cell types | #Bioinformatics #Database #Genomics #RNA #CircRNA #OpenScience 🧬 🖥️🧪🔓
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academic.oup.com/nar/advance-...
CircTarget: a comprehensive database of circRNA–target RNA interactions across multiple cell types
Abstract. Circular RNAs (circRNAs) are stable, widespread regulatory molecules produced primarily by back-splicing of pre-mRNAs, with critical roles in gen
academic.oup.com
January 1, 2026 at 4:42 PM
bffo.bsky.social
From @plos.org #Computational #Biology | Ten simple rules on how to set up an Innovation Boot Camp for exploitation of research results | #Education #Bioinformatics #OpenScience #OpenData #PLOSCBTSR 🧬 🖥️ 🧪 🔓 🇩🇪🇪🇸🇳🇴🇮🇹
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journals.plos.org/ploscompbiol...
December 31, 2025 at 12:29 AM
bffo.bsky.social
From @jchowning.bsky.social & colleagues in @plos.org #Computational #Biology | Ten simple rules for running a virtual program to introduce computational biology at the high school level | #Education #Bioinformatics #PLOSCBTSR #OpenScience 🧬 🖥️ 🧪 🔓
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journals.plos.org/ploscompbiol...
Ten simple rules for running a virtual program to introduce computational biology at the high school level
journals.plos.org
December 31, 2025 at 12:16 AM
bffo.bsky.social
From #NCBI Insight | GenBank Release 269.0 is now available | This release has 49.73 trillion bases and 6.03 billion records |
#Bioinformatics #OpenScience #OpenData | 🧬 🖥️ 🧪
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ncbiinsights.ncbi.nlm.nih.gov/2025/12/22/g...
GenBank Release 269.0 - NCBI Insights
GenBank release 269.0 (12/16/2025) is now available on the NCBI FTP site. This release has 49.73 trillion bases and 6.03 billion records. The current release has:  259,677,058 traditional records cont...
ncbiinsights.ncbi.nlm.nih.gov
December 26, 2025 at 8:34 PM
Reposted by BF Francis Ouellette
ianlmorgan.bsky.social
Merry Christmas 🎄🧪! Here's a video I made of the predicted structure for the protein MERRYCHRISTMAS. I used AlphaFold to predict the structure and then colored the backbone (green), amino acids by index (rainbow), and noncovalent interactions (dotted lines). #sciart #science #MolBio
December 25, 2025 at 5:59 PM
bffo.bsky.social
From @danielrigden.bsky.social & @xosegb.bsky.social in an #Editorial in @narjournal.bsky.social #NARDatabaseIssue | The 2026 Nucleic Acids Research database issue and the online molecular biology database collection | #Bioinformatics #Database #OpenScience 🧬🖥️🧪🔓
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academic.oup.com/nar/advance-...
The 2026 Nucleic Acids Research database issue and the online molecular biology database collection
Abstract. The 2026 Nucleic Acids Research database issue has 182 papers from across biology and neighbouring fields. Eighty-four of these papers describe n
academic.oup.com
December 24, 2025 at 12:36 PM
Reposted by BF Francis Ouellette
jaxeducation.bsky.social
Undergrads & graduating HS seniors: Applications are open for @jacksonlab.bsky.social’s Summer Student Program!

✅ Paid, 10-week mentored research experience
✅ Hands-on #genetics & #genomics research
✅ Professional development in #DataViz, #SciComm & peer review

Apply: www.jax.org/education-an...
Summer Student Program
A 10-week research fellowship for high school seniors and undergraduates excited by discovery, driven by curiosity, and eager to contribute to genetics and genomics research.
www.jax.org
December 15, 2025 at 2:41 PM
bffo.bsky.social
From the @geneontology.bsky.social team in the @narjournal.bsky.social #NARDatabaseIssue | The Gene Ontology knowledgebase in 2026 | #Bioinformatics #Database #OpenScience #GO #Ontology #GeneOnlology #OpenData 🧬 🖥️🧪🔓
⬇️ academic.oup.com/nar/advance-...
The Gene Ontology knowledgebase in 2026
Abstract. The Gene Ontology (GO) knowledgebase (https://geneontology.org) is a comprehensive resource describing the functions of genes. The GO knowledgeba
academic.oup.com
December 21, 2025 at 12:38 AM
Reposted by BF Francis Ouellette
rnacentral.bsky.social
We've just updated our RNAcentral Online Tutorial!
www.ebi.ac.uk/training/onl...

This tutorial provides an overview of RNAcentral and covers different ways of accessing and using the data. It's aimed at anyone with an interest in non-coding RNAs.

As always, we welcome your feedback!
RNAcentral - Exploring non-coding RNAs
RNAcentral - Exploring non-coding RNAs
www.ebi.ac.uk
November 5, 2025 at 6:07 PM
bffo.bsky.social
From the @rnacentral.bsky.social team in the @narjournal.bsky.social #NARDatabaseIssue | RNAcentral in 2026: genes and literature integration | #Bioinformatics #Database #OpenScience #Genomics #RNA #ncRNA 🧬 🖥️🧪🔓
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academic.oup.com/nar/advance-...
RNAcentral in 2026: genes and literature integration
Abstract. RNAcentral was founded in 2014 to serve as a comprehensive database of non-coding RNA sequences. It began by providing a single unified interface
academic.oup.com
December 19, 2025 at 1:59 AM
bffo.bsky.social
From the @nytimes.com | When will this stop? "the Trump-Kennedy Center"?



Trump and His Loyalists Move to Name the Kennedy Center for Him www.nytimes.com/2025/12/18/u...
December 18, 2025 at 8:24 PM
Reposted by BF Francis Ouellette
stephenturner.us
Bioinformatics frameworks for single-cell long-read sequencing: unlocking isoform-level resolution academic.oup.com/bib/article/... 🧬🖥️🧪
December 17, 2025 at 5:02 PM
Reposted by BF Francis Ouellette
humancellatlas.org
Thank you to everyone who attended the inaugural webinar in the “Towards a Human Exposome Atlas” series on 09 Dec. More than 350 people joined the event, bringing the @unesco.org, @exposomemoonshot.bsky.social and HCA communities together. 🖥️ 🧬 #Genomics #Exposome #SingleCell
December 17, 2025 at 5:30 PM
bffo.bsky.social
From @loiclnlg.bsky.social , @joannavonberg.bsky.social & colleagues in @plos.org #Computational #Biology | Eleven quick tips for organizing a data cleaning challenge | I like figure 1 | #Bioinformatics #Education #Data #PLOSCBQT #OpenScience 🧬 🖥️ 🧪 🔓 🇳🇱 
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journals.plos.org/ploscompbiol...
Eleven quick tips for organizing a data cleaning challenge
journals.plos.org
December 17, 2025 at 7:09 PM
bffo.bsky.social
From Kim Pruitt & team in the @narjournal.bsky.social #NARDatabaseIssue | #Database resources of the National Center for Biotechnology Information in 2026 | #Bioinformatics #OpenScience #Proteomics #Genomics #Education #Research #OpenData #OpenSource #NCBI 🧬 🖥️🧪🔓
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academic.oup.com/nar/advance-...
Database resources of the National Center for Biotechnology Information in 2026
Abstract. The National Center for Biotechnology Information (NCBI) provides biomedical data resources including PubMed®, a repository of citations and abst
academic.oup.com
December 13, 2025 at 3:54 PM
Reposted by BF Francis Ouellette
ppalagi.bsky.social
Congratulations, Francis! I have only half of your experience 😊. Thanks to you, and our fantastic writers, it’s been a pleasure to serve as a Section Editor for the #PLOSCB Education track.
December 11, 2025 at 4:14 PM
bffo.bsky.social
From Sameer Velankar & colleagues in @narjournal.bsky.social #NARDatabaseIssue | PDBe: enhanced structural data exploration to facilitate discovery | #Bioinformatics #Database #OpenScience #Proteomics #PDB 🧬 🖥️🧪🔓
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academic.oup.com/nar/advance-...
PDBe: enhanced structural data exploration to facilitate discovery
Abstract. Protein Data Bank in Europe (PDBe) is a founding member of the worldwide Protein Data Bank (wwPDB), delivering open access to experimentally dete
academic.oup.com
December 11, 2025 at 3:13 PM
bffo.bsky.social
My @plos.org #Computational #Biology anniversary, 12 years as a Section Editor at #PLOSCB | #OpenScience #OpenAccess #OpenData #OpenSource #OpenEducationalResources 🧬🖥️ 🧪🔓|
CC/ @ppalagi.bsky.social
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journals.plos.org/ploscompbiol...
Education in Computational Biology Today and Tomorrow
journals.plos.org
December 11, 2025 at 2:46 PM
bffo.bsky.social
From @pmadrigal.bsky.social @anilthanki.bsky.social + friends in @narjournal.bsky.social #NARDatabaseIssue | Expression Atlas in 2026: enabling #FAIR and open expression data through community collaboration and integration | #Bioinformatics #Database #Genomics 🧬🖥️🧪🔓
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academic.oup.com/nar/advance-...
Expression Atlas in 2026: enabling FAIR and open expression data through community collaboration and integration
Abstract. Expression Atlas (https://www.ebi.ac.uk/gxa/home) is EMBL-EBI’s comprehensive knowledgebase for gene and protein expression across tissues, cell
academic.oup.com
December 11, 2025 at 2:43 PM
bffo.bsky.social
In #JAMIA Open from @academic.oup.com | Biomedical data repositories require governance for artificial intelligence/machine learning applications at every step | #Data #Database #OpenScience #AI #ML 🧬 🖥️ 🧪 🔓
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academic.oup.com/jamiaopen/ar...
Validate User
academic.oup.com
December 11, 2025 at 2:47 AM
bffo.bsky.social
In @plos.org #Computational #Biology, there are now 300 "Ten Simple Rules" papers | #Education #Bioinformatics #PLOSCBTSR 🧬 🖥️ 🧪 🔓
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pubmed.ncbi.nlm.nih.gov?term=%28%22P...
("PLoS computational biology"[Journal]) AND ("ten simple rules" [Title]) - Search Results - PubMed
("PLoS computational biology"[Journal]) AND ("ten simple rules" [Title]) - Search Results - PubMed
pubmed.ncbi.nlm.nih.gov
December 10, 2025 at 5:51 PM
Reposted by BF Francis Ouellette
reactome.org
New Reactome paper in NAR 2026 Databases Issue: doi.org/10.1093/nar/...
Redesigned Angular interface
ReacFoam & entity-level visualizations
Multi-omics analysis tools
React-to-Me chatbot
FAIR-compliant, CoreTrustSeal certified, and ELIXIR-recognized
🖥️🧬
The Reactome Knowledgebase 2026
Abstract. The Reactome Knowledgebase (https://reactome.org) is a freely accessible, expert-curated, open-source, and open-data resource that describes huma
doi.org
December 8, 2025 at 9:26 PM
Reposted by BF Francis Ouellette
sailorrooscout.bsky.social
WELL NOW, would you look at that? A massive, 24-YEAR-LONG study of MORE THAN 1.2 MILLION people in Denmark found NO LINK between aluminum in childhood vaccines and autism, asthma, OR chronic disorders.

Aluminum is an ADJUVANT.

It ENHANCES your immune response to a vaccine.

That’s it.
December 5, 2025 at 5:00 PM
bffo.bsky.social
From @jhcepas.bsky.social and colleagues in the @narjournal.bsky.social #NARDatabaseIssue | eggNOG v7: phylogeny-based orthology predictions and functional annotations | #Bioinformatics #ProteinCentric #Database #OpenScience 🧬 🖥️🧪🇨🇭🇪🇸🇩🇪🔓
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academic.oup.com/nar/advance-...
eggNOG v7: phylogeny-based orthology predictions and functional annotations
Abstract. The eggNOG (evolutionary genealogy of genes: Non-supervised Orthologous Groups) database is a phylogenomic resource for orthology inference, evol
academic.oup.com
December 9, 2025 at 1:39 PM