Protein-protein, protein-RNA & protein-DNA interactions, structure & evolution
ML & DL
Biology of genome maintenance
Women/diversity in science
Personal account
A tripartite protein complex promotes DNA transport during natural transformation in Firmicutes www.pnas.org/doi/10.1073/...
I am super happy about it, for many reasons!
👥 It was a great collaborative project with Calum @chgjohnston.bsky.social and J. Pablo Radicella, designed a long time ago (in the pre-AlphaFold era - can you imagine?) together with @polardlab.bsky.social and @raphguerois.bsky.social
Envie de découvrir (ou faire découvrir) des femmes scientifiques ? J'ai rassemblé plein de ressources ici ⬇️
www.linkedin.com/pulse/envie-...
Et mon starter pack de chercheuses sur bluesky go.bsky.app/TBEzKC
Envie de découvrir (ou faire découvrir) des femmes scientifiques ? J'ai rassemblé plein de ressources ici ⬇️
www.linkedin.com/pulse/envie-...
Et mon starter pack de chercheuses sur bluesky go.bsky.app/TBEzKC
📄 www.science.org/doi/10.1126/...
🌐 search.foldseek.com/foldmason
💾 github.com/steineggerla...
📄 www.science.org/doi/10.1126/...
🌐 search.foldseek.com/foldmason
💾 github.com/steineggerla...
jobs.uni-jena.de/jobposting/c...
jobs.uni-jena.de/jobposting/c...
Keywords not in specific order: intergenic ORFs, de novo genes, GC content, foldability, genetic code, ancestral sequence reconstruction and more :)
Keywords not in specific order: intergenic ORFs, de novo genes, GC content, foldability, genetic code, ancestral sequence reconstruction and more :)
Today in @science.org, we introduce Conformational Biasing (CB), a simple and scalable computational method that uses contrastive scoring by inverse folding models to identify conformation-biasing mutations.
Today in @science.org, we introduce Conformational Biasing (CB), a simple and scalable computational method that uses contrastive scoring by inverse folding models to identify conformation-biasing mutations.
issues.org/american-sci...
issues.org/american-sci...
Here we show many bacterial isolates contain non-temperate phages that can persist through restreaking.
Thanks to all co-authors for such a great collaboration!
Here we show many bacterial isolates contain non-temperate phages that can persist through restreaking.
Thanks to all co-authors for such a great collaboration!
thanks to @i2bcparissaclay.bsky.social for its financial support through epiRNA programs
academic.oup.com/nargab/artic...
thanks to @i2bcparissaclay.bsky.social for its financial support through epiRNA programs
academic.oup.com/nargab/artic...
Many thanks to all of our depositors and biocurators more making these important data available to all
Details:
Many thanks to all of our depositors and biocurators more making these important data available to all
Details:
Au programme de ces 3 jours : analyse de structures protéiques en 3D, grâce aux outils d’intelligence artificielle tels qu’AlphaFold et initiation à l’utilisation du supercalculateur Jean Zay (IDRIS - @cnrs.fr ) !
Au programme de ces 3 jours : analyse de structures protéiques en 3D, grâce aux outils d’intelligence artificielle tels qu’AlphaFold et initiation à l’utilisation du supercalculateur Jean Zay (IDRIS - @cnrs.fr ) !
Avec une coquille : le titre et la liste des postes disent "chargés de recherche de classe normale" mais l'article 1 dit "directeurs de recherche de 1ère classe". Rectificatif à venir.
Avec une coquille : le titre et la liste des postes disent "chargés de recherche de classe normale" mais l'article 1 dit "directeurs de recherche de 1ère classe". Rectificatif à venir.
Le concours n'est pas ouvert ?
Le concours n'est pas ouvert ?
🧵1/4 Excited to share our work on AI-guided design of minimal RNA-guided nucleases. Amazing work by @petrskopintsev.bsky.social @isabelesain.bsky.social @evandeturk.bsky.social et al!
Multi-lab collaboration @banfieldlab.bsky.social @jhdcate.bsky.social @jacobsenucla.bsky.social🧬
🔗👇
🧵1/4 Excited to share our work on AI-guided design of minimal RNA-guided nucleases. Amazing work by @petrskopintsev.bsky.social @isabelesain.bsky.social @evandeturk.bsky.social et al!
Multi-lab collaboration @banfieldlab.bsky.social @jhdcate.bsky.social @jacobsenucla.bsky.social🧬
🔗👇
Our study reveals how cohesin guides focused and accurate homology search.
Read more 👉 www.science.org/doi/10.1126/...
Follow along for key insights and updates! 🧵
Our study reveals how cohesin guides focused and accurate homology search.
Read more 👉 www.science.org/doi/10.1126/...
Follow along for key insights and updates! 🧵
✍️ Yoshiharu Yamaichi
🤝 @cnrs-paris-saclay.bsky.social @i2bcparissaclay.bsky.social @univparissaclay.bsky.social
@cea-paris-saclay.bsky.social
📕 @narjournal.bsky.social | buff.ly/iEqMc04
✍️ Yoshiharu Yamaichi
🤝 @cnrs-paris-saclay.bsky.social @i2bcparissaclay.bsky.social @univparissaclay.bsky.social
@cea-paris-saclay.bsky.social
📕 @narjournal.bsky.social | buff.ly/iEqMc04
Elegant PNAS paper on the ComEC/ComFA/ComFC complex in bacterial transformation. AF3 predictions validated by clever mutagenesis. We tried for years to solve this by cryo-EM/crystallography - never succeeded.
Elegant PNAS paper on the ComEC/ComFA/ComFC complex in bacterial transformation. AF3 predictions validated by clever mutagenesis. We tried for years to solve this by cryo-EM/crystallography - never succeeded.
We describe differences from E. coli and discuss links to decoding of stress-related codons 🦠
Huge thanks to amazing co-authors and collaborators!
@plos.org #rnasky #microsky #tRNAmodifications
We describe differences from E. coli and discuss links to decoding of stress-related codons 🦠
Huge thanks to amazing co-authors and collaborators!
@plos.org #rnasky #microsky #tRNAmodifications
Douze établissements seraient en situation budgétaire jugée "insoutenable" car dépassant l’un des trois critères.
#ESR
Douze établissements seraient en situation budgétaire jugée "insoutenable" car dépassant l’un des trois critères.
#ESR