Peter Dougherty
peterdoug.bsky.social
Peter Dougherty
@peterdoug.bsky.social
PhD student at the University of Copenhagen, interested in microbiology and bioinformatics
Reposted by Peter Dougherty
#NewResearch

The long-term existence of diverse virulent phages within cultures of Escherichia coli and others challenges the virulent–temperate dichotomy and points to non-canonical phage lifestyles.

#MicroSky 🦠 @peterdoug.bsky.social @emggroupucph.bsky.social

www.nature.com/articles/s41...
Persistent virulent phages exist across bacterial isolates - Nature Microbiology
The long-term existence of diverse virulent phages within cultures of Escherichia coli and others challenges the virulent–temperate dichotomy and points to non-canonical phage lifestyles.
www.nature.com
January 2, 2026 at 2:05 PM
Bacteriophages are normally classified as either virulent or temperate. Reality is, of course, more complicated!
Here we show many bacterial isolates contain non-temperate phages that can persist through restreaking.
Thanks to all co-authors for such a great collaboration!
December 29, 2025 at 3:18 PM
Are there virulent phages hiding in your bacterial culture? Here we find hundreds of virulent phage genomes in bacterial genome assemblies. Bioinformatic and experimental evidence indicate these are not contaminations, but represent persistent infections.

www.biorxiv.org/content/10.1...
Persistent virulent phages exist in bacterial isolates
Despite the immense diversity of tailed bacteriophages, they are traditionally classified as either virulent or temperate, with only the latter thought capable of long-term persistence in bacterial ce...
www.biorxiv.org
January 2, 2025 at 10:06 AM