Gonzalo Aparicio
@gaparicio.bsky.social
Neural development enthusiast, from neurulation to cell differentiation. Chick and zebrafish embryos 🐣🐟🔬. Facultad de Ciencias, Universidad de la República, Uruguay. @fzolessi.bsky.social lab #DevelopmentalBiology #Neuroepithelium #Retina #CellPolarity 🚲🇺🇾
Reposted by Gonzalo Aparicio
'Giant Steps' is an absolute rush
Read more in our Beginner's Guide to John Coltrane: www.treblezine.com/best-john-co...
Read more in our Beginner's Guide to John Coltrane: www.treblezine.com/best-john-co...
January 31, 2026 at 9:19 PM
'Giant Steps' is an absolute rush
Read more in our Beginner's Guide to John Coltrane: www.treblezine.com/best-john-co...
Read more in our Beginner's Guide to John Coltrane: www.treblezine.com/best-john-co...
Reposted by Gonzalo Aparicio
JCS snapshot - Tracking coordinated cellular dynamics in time-lapse microscopy with ARCOS.px
@macdobry.bsky.social presents the key findings from their recent JCS paper with @bgraedel.bsky.social and colleagues @olivierpertz.bsky.social.
journals.biologists.com/jcs/article/...
@macdobry.bsky.social presents the key findings from their recent JCS paper with @bgraedel.bsky.social and colleagues @olivierpertz.bsky.social.
journals.biologists.com/jcs/article/...
January 29, 2026 at 2:24 PM
JCS snapshot - Tracking coordinated cellular dynamics in time-lapse microscopy with ARCOS.px
@macdobry.bsky.social presents the key findings from their recent JCS paper with @bgraedel.bsky.social and colleagues @olivierpertz.bsky.social.
journals.biologists.com/jcs/article/...
@macdobry.bsky.social presents the key findings from their recent JCS paper with @bgraedel.bsky.social and colleagues @olivierpertz.bsky.social.
journals.biologists.com/jcs/article/...
Reposted by Gonzalo Aparicio
Juana Molina's excellent 'DOGA' comprises some of her most warped yet immediate material to date
@1000timesjeff.bsky.social reviews
www.treblezine.com/juana-molina...
@1000timesjeff.bsky.social reviews
www.treblezine.com/juana-molina...
Juana Molina : DOGA - Treble
The Argentine artist's first new album in eight years is some of her most immediate and mesmerizing to date
www.treblezine.com
January 23, 2026 at 4:56 PM
Juana Molina's excellent 'DOGA' comprises some of her most warped yet immediate material to date
@1000timesjeff.bsky.social reviews
www.treblezine.com/juana-molina...
@1000timesjeff.bsky.social reviews
www.treblezine.com/juana-molina...
Reposted by Gonzalo Aparicio
some nice circular micropatterns by @bgraedel.bsky.social and msc student moritz in @olivierpertz.bsky.social lab! stamp printed with our microfab method.
January 20, 2026 at 8:12 AM
some nice circular micropatterns by @bgraedel.bsky.social and msc student moritz in @olivierpertz.bsky.social lab! stamp printed with our microfab method.
Reposted by Gonzalo Aparicio
🎉 The Developmental Mechanics Seminar Series is back!
🗓️ Thurs, Jan 22
🎙️ Opening talks:
🧬Guy Tanentzapf (UBC)
— How cell adhesion molecules wire into the cytoskeleton
🌀Juan Manuel Gomez Elliff (EMBL)
@gomezjm-devmech.bsky.social
— Mapping tissue mechanics with Brillouin microscopy
🗓️ Thurs, Jan 22
🎙️ Opening talks:
🧬Guy Tanentzapf (UBC)
— How cell adhesion molecules wire into the cytoskeleton
🌀Juan Manuel Gomez Elliff (EMBL)
@gomezjm-devmech.bsky.social
— Mapping tissue mechanics with Brillouin microscopy
International Developmental Mechanics Seminar Series
Please fill out the following survey if you are interested in the 2025-2026 International Zoom Seminars on Developmental Mechanics.
tinyurl.com
January 19, 2026 at 11:13 AM
🎉 The Developmental Mechanics Seminar Series is back!
🗓️ Thurs, Jan 22
🎙️ Opening talks:
🧬Guy Tanentzapf (UBC)
— How cell adhesion molecules wire into the cytoskeleton
🌀Juan Manuel Gomez Elliff (EMBL)
@gomezjm-devmech.bsky.social
— Mapping tissue mechanics with Brillouin microscopy
🗓️ Thurs, Jan 22
🎙️ Opening talks:
🧬Guy Tanentzapf (UBC)
— How cell adhesion molecules wire into the cytoskeleton
🌀Juan Manuel Gomez Elliff (EMBL)
@gomezjm-devmech.bsky.social
— Mapping tissue mechanics with Brillouin microscopy
Reposted by Gonzalo Aparicio
What's larger, a protein or its templating mRNA ?
> The mRNA is much larger.
⬛ 𝐀 𝐬𝐞𝐧𝐬𝐞 𝐨𝐟 𝐬𝐜𝐚𝐥𝐞 -- 𝐪𝐮𝐚𝐧𝐭𝐢𝐭𝐚𝐭𝐢𝐯𝐞 𝐢𝐧𝐭𝐮𝐢𝐭𝐢𝐨𝐧 & 𝐜𝐨𝐧𝐬𝐭𝐫𝐚𝐢𝐧𝐭𝐬 -- 𝐢𝐬 𝐚 𝐩𝐨𝐰𝐞𝐫𝐟𝐮𝐥 𝐞𝐧𝐚𝐛𝐥𝐞𝐫 𝐨𝐟 𝐫𝐞𝐬𝐞𝐚𝐫𝐜𝐡.
The figure shows myoglobin protein drawn to scale next to its mRNA template. The coding sequence of an mRNA ...
> The mRNA is much larger.
⬛ 𝐀 𝐬𝐞𝐧𝐬𝐞 𝐨𝐟 𝐬𝐜𝐚𝐥𝐞 -- 𝐪𝐮𝐚𝐧𝐭𝐢𝐭𝐚𝐭𝐢𝐯𝐞 𝐢𝐧𝐭𝐮𝐢𝐭𝐢𝐨𝐧 & 𝐜𝐨𝐧𝐬𝐭𝐫𝐚𝐢𝐧𝐭𝐬 -- 𝐢𝐬 𝐚 𝐩𝐨𝐰𝐞𝐫𝐟𝐮𝐥 𝐞𝐧𝐚𝐛𝐥𝐞𝐫 𝐨𝐟 𝐫𝐞𝐬𝐞𝐚𝐫𝐜𝐡.
The figure shows myoglobin protein drawn to scale next to its mRNA template. The coding sequence of an mRNA ...
January 17, 2026 at 1:29 PM
What's larger, a protein or its templating mRNA ?
> The mRNA is much larger.
⬛ 𝐀 𝐬𝐞𝐧𝐬𝐞 𝐨𝐟 𝐬𝐜𝐚𝐥𝐞 -- 𝐪𝐮𝐚𝐧𝐭𝐢𝐭𝐚𝐭𝐢𝐯𝐞 𝐢𝐧𝐭𝐮𝐢𝐭𝐢𝐨𝐧 & 𝐜𝐨𝐧𝐬𝐭𝐫𝐚𝐢𝐧𝐭𝐬 -- 𝐢𝐬 𝐚 𝐩𝐨𝐰𝐞𝐫𝐟𝐮𝐥 𝐞𝐧𝐚𝐛𝐥𝐞𝐫 𝐨𝐟 𝐫𝐞𝐬𝐞𝐚𝐫𝐜𝐡.
The figure shows myoglobin protein drawn to scale next to its mRNA template. The coding sequence of an mRNA ...
> The mRNA is much larger.
⬛ 𝐀 𝐬𝐞𝐧𝐬𝐞 𝐨𝐟 𝐬𝐜𝐚𝐥𝐞 -- 𝐪𝐮𝐚𝐧𝐭𝐢𝐭𝐚𝐭𝐢𝐯𝐞 𝐢𝐧𝐭𝐮𝐢𝐭𝐢𝐨𝐧 & 𝐜𝐨𝐧𝐬𝐭𝐫𝐚𝐢𝐧𝐭𝐬 -- 𝐢𝐬 𝐚 𝐩𝐨𝐰𝐞𝐫𝐟𝐮𝐥 𝐞𝐧𝐚𝐛𝐥𝐞𝐫 𝐨𝐟 𝐫𝐞𝐬𝐞𝐚𝐫𝐜𝐡.
The figure shows myoglobin protein drawn to scale next to its mRNA template. The coding sequence of an mRNA ...
Reposted by Gonzalo Aparicio
🧪 Wondering if HFSP Research Grants are the right fit for you?
You might be a good match if your idea is:
🔹 Too bold or risky for traditional funders
🔹 Strongly interdisciplinary
🔹 Best tackled by an international team
🔗zurl.co/6oyBA
#HFSPResearchGrants #sts
You might be a good match if your idea is:
🔹 Too bold or risky for traditional funders
🔹 Strongly interdisciplinary
🔹 Best tackled by an international team
🔗zurl.co/6oyBA
#HFSPResearchGrants #sts
December 29, 2025 at 9:32 AM
🧪 Wondering if HFSP Research Grants are the right fit for you?
You might be a good match if your idea is:
🔹 Too bold or risky for traditional funders
🔹 Strongly interdisciplinary
🔹 Best tackled by an international team
🔗zurl.co/6oyBA
#HFSPResearchGrants #sts
You might be a good match if your idea is:
🔹 Too bold or risky for traditional funders
🔹 Strongly interdisciplinary
🔹 Best tackled by an international team
🔗zurl.co/6oyBA
#HFSPResearchGrants #sts
Reposted by Gonzalo Aparicio
Old school cell division data hand drawn by Wacław Mayzel while he looked through his microscope; circa 1884. #CellBiology
December 28, 2025 at 3:17 PM
Old school cell division data hand drawn by Wacław Mayzel while he looked through his microscope; circa 1884. #CellBiology
Reposted by Gonzalo Aparicio
#Mastodon, the Command Center for Large-Scale Lineage-Tracing Microscopy Datasets, is finally heading for publication (well, let's see). To #cite or not to cite shall no longer be the question 🙃, because the #preprint. Software is available in every #Fiji near you.
www.biorxiv.org/content/10.6...
www.biorxiv.org/content/10.6...
December 13, 2025 at 6:14 PM
#Mastodon, the Command Center for Large-Scale Lineage-Tracing Microscopy Datasets, is finally heading for publication (well, let's see). To #cite or not to cite shall no longer be the question 🙃, because the #preprint. Software is available in every #Fiji near you.
www.biorxiv.org/content/10.6...
www.biorxiv.org/content/10.6...
Reposted by Gonzalo Aparicio
Organelles do NOT have a single uniform pH.
And if you think they must, because “protons diffuse fast,” this paper is for you.
A thread on why that assumption is wrong; and what we found instead. 🧵 1/n
And if you think they must, because “protons diffuse fast,” this paper is for you.
A thread on why that assumption is wrong; and what we found instead. 🧵 1/n
Organelles harbour pH gradients https://www.biorxiv.org/content/10.64898/2025.12.12.694065v1
December 17, 2025 at 12:46 AM
Organelles do NOT have a single uniform pH.
And if you think they must, because “protons diffuse fast,” this paper is for you.
A thread on why that assumption is wrong; and what we found instead. 🧵 1/n
And if you think they must, because “protons diffuse fast,” this paper is for you.
A thread on why that assumption is wrong; and what we found instead. 🧵 1/n
Reposted by Gonzalo Aparicio
What would Santa Waclaw Mayzel give the good little boys and girls of the world?
Festive drawings of a cell dividing into two daughter cells of course!
Read more about Waclaw Mayzel here: link.springer.com/article/10.1...
#CellBiology
Festive drawings of a cell dividing into two daughter cells of course!
Read more about Waclaw Mayzel here: link.springer.com/article/10.1...
#CellBiology
December 22, 2025 at 4:10 PM
What would Santa Waclaw Mayzel give the good little boys and girls of the world?
Festive drawings of a cell dividing into two daughter cells of course!
Read more about Waclaw Mayzel here: link.springer.com/article/10.1...
#CellBiology
Festive drawings of a cell dividing into two daughter cells of course!
Read more about Waclaw Mayzel here: link.springer.com/article/10.1...
#CellBiology
Reposted by Gonzalo Aparicio
Reconocimiento internacional
La técnica en Biotecnología Bárbara Miller recibió el segundo premio del concurso Biosol 2025, otorgado por la Universidad de Copenhague, en la categoría «por fuera de Europa», por una propuesta con impacto ambiental. 🧵
La técnica en Biotecnología Bárbara Miller recibió el segundo premio del concurso Biosol 2025, otorgado por la Universidad de Copenhague, en la categoría «por fuera de Europa», por una propuesta con impacto ambiental. 🧵
December 19, 2025 at 7:19 PM
Reconocimiento internacional
La técnica en Biotecnología Bárbara Miller recibió el segundo premio del concurso Biosol 2025, otorgado por la Universidad de Copenhague, en la categoría «por fuera de Europa», por una propuesta con impacto ambiental. 🧵
La técnica en Biotecnología Bárbara Miller recibió el segundo premio del concurso Biosol 2025, otorgado por la Universidad de Copenhague, en la categoría «por fuera de Europa», por una propuesta con impacto ambiental. 🧵
Reposted by Gonzalo Aparicio
Attention scientists from all over the world🙃
The Call for Letters of Intent for #HFSPResearchGrants 2027 is now open! 🧪
Get your international & interdisciplinary team. It's time to put your bold research idea into practice!
🔗https://bit.ly/48VsGCG
📅 15 Dec 2025–26 Mar 2026
#sts #LifeSciences
The Call for Letters of Intent for #HFSPResearchGrants 2027 is now open! 🧪
Get your international & interdisciplinary team. It's time to put your bold research idea into practice!
🔗https://bit.ly/48VsGCG
📅 15 Dec 2025–26 Mar 2026
#sts #LifeSciences
December 15, 2025 at 2:52 PM
Attention scientists from all over the world🙃
The Call for Letters of Intent for #HFSPResearchGrants 2027 is now open! 🧪
Get your international & interdisciplinary team. It's time to put your bold research idea into practice!
🔗https://bit.ly/48VsGCG
📅 15 Dec 2025–26 Mar 2026
#sts #LifeSciences
The Call for Letters of Intent for #HFSPResearchGrants 2027 is now open! 🧪
Get your international & interdisciplinary team. It's time to put your bold research idea into practice!
🔗https://bit.ly/48VsGCG
📅 15 Dec 2025–26 Mar 2026
#sts #LifeSciences
Reposted by Gonzalo Aparicio
I was invited by @focalplane.bsky.social to write a short description about it:
focalplane.biologists.com/2025/12/12/a...
focalplane.biologists.com/2025/12/12/a...
December 15, 2025 at 8:40 AM
I was invited by @focalplane.bsky.social to write a short description about it:
focalplane.biologists.com/2025/12/12/a...
focalplane.biologists.com/2025/12/12/a...
Reposted by Gonzalo Aparicio
🌊 Developmental biologists say gastrulation is the most important moment of your life… and this sea urchin is making sure it looks fabulous for the occasion 💅
🔴 Laminin 🟢 Skeletal cells 🔵 Membranes 📸 Image from David McClay #FluorescenceFriday #DevBio
🔴 Laminin 🟢 Skeletal cells 🔵 Membranes 📸 Image from David McClay #FluorescenceFriday #DevBio
November 14, 2025 at 9:17 PM
🌊 Developmental biologists say gastrulation is the most important moment of your life… and this sea urchin is making sure it looks fabulous for the occasion 💅
🔴 Laminin 🟢 Skeletal cells 🔵 Membranes 📸 Image from David McClay #FluorescenceFriday #DevBio
🔴 Laminin 🟢 Skeletal cells 🔵 Membranes 📸 Image from David McClay #FluorescenceFriday #DevBio
Reposted by Gonzalo Aparicio
🎄 Day 4 of the 24 Days of Development ✨🧬
In 1984, Drosophila homeotic genes were found to be conserved across animals, including humans 🧬🐸. This article highlights a shared genetic toolkit for embryonic development 🔬🌟🎁 doi.org/10.1016/j.yd...
In 1984, Drosophila homeotic genes were found to be conserved across animals, including humans 🧬🐸. This article highlights a shared genetic toolkit for embryonic development 🔬🌟🎁 doi.org/10.1016/j.yd...
December 4, 2025 at 9:44 PM
🎄 Day 4 of the 24 Days of Development ✨🧬
In 1984, Drosophila homeotic genes were found to be conserved across animals, including humans 🧬🐸. This article highlights a shared genetic toolkit for embryonic development 🔬🌟🎁 doi.org/10.1016/j.yd...
In 1984, Drosophila homeotic genes were found to be conserved across animals, including humans 🧬🐸. This article highlights a shared genetic toolkit for embryonic development 🔬🌟🎁 doi.org/10.1016/j.yd...
Reposted by Gonzalo Aparicio
📜We are thrilled to announce that the latest MorphoNet paper is officially published 🎉 ! Discover 5 varied use cases in which MorphoNet helps segment, curate, evaluate & validate complex 3D+t datasets, and much more 🧑💻 ! Read at @elife.bsky.social : doi.org/10.7554/eLif...
December 3, 2025 at 12:28 PM
📜We are thrilled to announce that the latest MorphoNet paper is officially published 🎉 ! Discover 5 varied use cases in which MorphoNet helps segment, curate, evaluate & validate complex 3D+t datasets, and much more 🧑💻 ! Read at @elife.bsky.social : doi.org/10.7554/eLif...
Reposted by Gonzalo Aparicio
🚨 New preprint!
We built a single-cell atlas of 14 multilayered epithelia and revealed a conserved transcriptomic program guiding tissue architecture and fate composition. Our work brings decades of tissue-specific studies together into a unified evo-devo framework.
www.biorxiv.org/content/10.1...
We built a single-cell atlas of 14 multilayered epithelia and revealed a conserved transcriptomic program guiding tissue architecture and fate composition. Our work brings decades of tissue-specific studies together into a unified evo-devo framework.
www.biorxiv.org/content/10.1...
November 17, 2025 at 12:33 PM
🚨 New preprint!
We built a single-cell atlas of 14 multilayered epithelia and revealed a conserved transcriptomic program guiding tissue architecture and fate composition. Our work brings decades of tissue-specific studies together into a unified evo-devo framework.
www.biorxiv.org/content/10.1...
We built a single-cell atlas of 14 multilayered epithelia and revealed a conserved transcriptomic program guiding tissue architecture and fate composition. Our work brings decades of tissue-specific studies together into a unified evo-devo framework.
www.biorxiv.org/content/10.1...
Reposted by Gonzalo Aparicio
Paper alert! Mechanical conditions preventing live cell extrusion during primary neurulation in amniotes. @sabr-bio.bsky.social article published as pre-proof in @cellsdev.bsky.social! doi.org/10.1016/j.cd...
November 28, 2025 at 6:47 PM
Paper alert! Mechanical conditions preventing live cell extrusion during primary neurulation in amniotes. @sabr-bio.bsky.social article published as pre-proof in @cellsdev.bsky.social! doi.org/10.1016/j.cd...
Reposted by Gonzalo Aparicio
Complete your profile and join the Network !
This survey is meant for Latin American developmental biologists (investigators, postdocs, students, and technicians) working in Latin America and abroad.
lasdb-development.org/pages/Latin_...
This survey is meant for Latin American developmental biologists (investigators, postdocs, students, and technicians) working in Latin America and abroad.
lasdb-development.org/pages/Latin_...
October 13, 2025 at 1:56 AM
Complete your profile and join the Network !
This survey is meant for Latin American developmental biologists (investigators, postdocs, students, and technicians) working in Latin America and abroad.
lasdb-development.org/pages/Latin_...
This survey is meant for Latin American developmental biologists (investigators, postdocs, students, and technicians) working in Latin America and abroad.
lasdb-development.org/pages/Latin_...
Reposted by Gonzalo Aparicio
We just released a new major version of TrackMate (v8), the cell and organelle tracking plugin of Fiji.
It ships many new features, detailed below, but that are articulated around the following:
It ships many new features, detailed below, but that are articulated around the following:
November 20, 2025 at 11:42 AM
We just released a new major version of TrackMate (v8), the cell and organelle tracking plugin of Fiji.
It ships many new features, detailed below, but that are articulated around the following:
It ships many new features, detailed below, but that are articulated around the following:
Reposted by Gonzalo Aparicio
quick test with SAM3 - impressed with how well it seems to track long protrusions? prompted for "cell", does not find anything when looking for "fibroblast" or "nucleus"
November 19, 2025 at 8:15 PM
quick test with SAM3 - impressed with how well it seems to track long protrusions? prompted for "cell", does not find anything when looking for "fibroblast" or "nucleus"
Reposted by Gonzalo Aparicio
Felix Zhou's u-Segment3D is out:
www.nature.com/articles/s41...
It leverages 2D cell segmentations from orthoviews to generate a ‘consensus’ 3D segmentation.
It does a great job on segmenting densely packed samples, and we have used the algorithm in many applications.
www.nature.com/articles/s41...
It leverages 2D cell segmentations from orthoviews to generate a ‘consensus’ 3D segmentation.
It does a great job on segmenting densely packed samples, and we have used the algorithm in many applications.
November 12, 2025 at 2:41 AM
Felix Zhou's u-Segment3D is out:
www.nature.com/articles/s41...
It leverages 2D cell segmentations from orthoviews to generate a ‘consensus’ 3D segmentation.
It does a great job on segmenting densely packed samples, and we have used the algorithm in many applications.
www.nature.com/articles/s41...
It leverages 2D cell segmentations from orthoviews to generate a ‘consensus’ 3D segmentation.
It does a great job on segmenting densely packed samples, and we have used the algorithm in many applications.
Reposted by Gonzalo Aparicio
"His secret weapons were an unquenchable curiosity and continuing hands-on experimentation at the bench with his beautiful frog embryos and oocytes".
A thoughtful tribute to the life of Sir John Gurdon by Edward M. De Robertis that we really recommend everyone to read.
doi.org/10.1016/j.cd...
A thoughtful tribute to the life of Sir John Gurdon by Edward M. De Robertis that we really recommend everyone to read.
doi.org/10.1016/j.cd...
November 7, 2025 at 9:12 PM
"His secret weapons were an unquenchable curiosity and continuing hands-on experimentation at the bench with his beautiful frog embryos and oocytes".
A thoughtful tribute to the life of Sir John Gurdon by Edward M. De Robertis that we really recommend everyone to read.
doi.org/10.1016/j.cd...
A thoughtful tribute to the life of Sir John Gurdon by Edward M. De Robertis that we really recommend everyone to read.
doi.org/10.1016/j.cd...
Reposted by Gonzalo Aparicio
Just published! We share an open-source workflow to measure membrane thickness from tomograms, including a tutorial with 3D visualizations. We analyze thickness variations across organelles and reflect on where to define a membrane boundary. @becklab.bsky.social #teamtomo rupress.org/jcb/article/...
November 6, 2025 at 7:38 AM
Just published! We share an open-source workflow to measure membrane thickness from tomograms, including a tutorial with 3D visualizations. We analyze thickness variations across organelles and reflect on where to define a membrane boundary. @becklab.bsky.social #teamtomo rupress.org/jcb/article/...