Gonzalo Aparicio
@gaparicio.bsky.social
Neural development enthusiast, from neurulation to cell differentiation. Chick and zebrafish embryos 🐣🐟🔬. Facultad de Ciencias, Universidad de la República, Uruguay. @fzolessi.bsky.social lab #DevelopmentalBiology #Neuroepithelium #Retina #CellPolarity 🚲🇺🇾
Reposted by Gonzalo Aparicio
Felix Zhou's u-Segment3D is out:
www.nature.com/articles/s41...
It leverages 2D cell segmentations from orthoviews to generate a ‘consensus’ 3D segmentation.
It does a great job on segmenting densely packed samples, and we have used the algorithm in many applications.
www.nature.com/articles/s41...
It leverages 2D cell segmentations from orthoviews to generate a ‘consensus’ 3D segmentation.
It does a great job on segmenting densely packed samples, and we have used the algorithm in many applications.
November 12, 2025 at 2:41 AM
Felix Zhou's u-Segment3D is out:
www.nature.com/articles/s41...
It leverages 2D cell segmentations from orthoviews to generate a ‘consensus’ 3D segmentation.
It does a great job on segmenting densely packed samples, and we have used the algorithm in many applications.
www.nature.com/articles/s41...
It leverages 2D cell segmentations from orthoviews to generate a ‘consensus’ 3D segmentation.
It does a great job on segmenting densely packed samples, and we have used the algorithm in many applications.
Reposted by Gonzalo Aparicio
"His secret weapons were an unquenchable curiosity and continuing hands-on experimentation at the bench with his beautiful frog embryos and oocytes".
A thoughtful tribute to the life of Sir John Gurdon by Edward M. De Robertis that we really recommend everyone to read.
doi.org/10.1016/j.cd...
A thoughtful tribute to the life of Sir John Gurdon by Edward M. De Robertis that we really recommend everyone to read.
doi.org/10.1016/j.cd...
November 7, 2025 at 9:12 PM
"His secret weapons were an unquenchable curiosity and continuing hands-on experimentation at the bench with his beautiful frog embryos and oocytes".
A thoughtful tribute to the life of Sir John Gurdon by Edward M. De Robertis that we really recommend everyone to read.
doi.org/10.1016/j.cd...
A thoughtful tribute to the life of Sir John Gurdon by Edward M. De Robertis that we really recommend everyone to read.
doi.org/10.1016/j.cd...
Reposted by Gonzalo Aparicio
Just published! We share an open-source workflow to measure membrane thickness from tomograms, including a tutorial with 3D visualizations. We analyze thickness variations across organelles and reflect on where to define a membrane boundary. @becklab.bsky.social #teamtomo rupress.org/jcb/article/...
November 6, 2025 at 7:38 AM
Just published! We share an open-source workflow to measure membrane thickness from tomograms, including a tutorial with 3D visualizations. We analyze thickness variations across organelles and reflect on where to define a membrane boundary. @becklab.bsky.social #teamtomo rupress.org/jcb/article/...
Reposted by Gonzalo Aparicio
My new ImageJ / Fiji toolkit is out 🔥! The goal is to make image handling & visualization easy, with an intuitive interface! Install it on Fiji with the "Image Viewer" update site
#microscopy #ImageJ #FluorescenceFriday #microscopyMonday
imagej.net/plugins/imag...
#microscopy #ImageJ #FluorescenceFriday #microscopyMonday
imagej.net/plugins/imag...
November 4, 2025 at 10:40 PM
My new ImageJ / Fiji toolkit is out 🔥! The goal is to make image handling & visualization easy, with an intuitive interface! Install it on Fiji with the "Image Viewer" update site
#microscopy #ImageJ #FluorescenceFriday #microscopyMonday
imagej.net/plugins/imag...
#microscopy #ImageJ #FluorescenceFriday #microscopyMonday
imagej.net/plugins/imag...
Reposted by Gonzalo Aparicio
🐸 Xenopus laevis 💚 The frog that shaped modern developmental biology! ✨ Xenopus embryos have revealed how the body axis forms, cells choose their fate, and tissues self-organize during early development 📹 Video by Bioquest Sudio and Xenbase #ModelMonday #DevBio
November 3, 2025 at 8:01 PM
🐸 Xenopus laevis 💚 The frog that shaped modern developmental biology! ✨ Xenopus embryos have revealed how the body axis forms, cells choose their fate, and tissues self-organize during early development 📹 Video by Bioquest Sudio and Xenbase #ModelMonday #DevBio
Reposted by Gonzalo Aparicio
Cool rotifer feeding with it's cilia beating
🐙🧪
🐙🧪
November 1, 2025 at 8:41 PM
Cool rotifer feeding with it's cilia beating
🐙🧪
🐙🧪
Reposted by Gonzalo Aparicio
#HappyFluorescenceFriday #microscopycommunity
Got an idea for an image analysis workshop? Share it at Halfway to I2K: Online Tutorials on Image Analysis (Nov 17–19, 2025), held with Zoom Events!
Submit by Oct 31: buff.ly/lMhK4vz
Website: buff.ly/QP36RZB
Register for the workshops: buff.ly/8nNAI18
Got an idea for an image analysis workshop? Share it at Halfway to I2K: Online Tutorials on Image Analysis (Nov 17–19, 2025), held with Zoom Events!
Submit by Oct 31: buff.ly/lMhK4vz
Website: buff.ly/QP36RZB
Register for the workshops: buff.ly/8nNAI18
Airtable | Everyone's app platform
Airtable is a low-code platform for building collaborative apps. Customize your workflow, collaborate, and achieve ambitious outcomes. Get started for free.
buff.ly
October 31, 2025 at 3:02 PM
#HappyFluorescenceFriday #microscopycommunity
Got an idea for an image analysis workshop? Share it at Halfway to I2K: Online Tutorials on Image Analysis (Nov 17–19, 2025), held with Zoom Events!
Submit by Oct 31: buff.ly/lMhK4vz
Website: buff.ly/QP36RZB
Register for the workshops: buff.ly/8nNAI18
Got an idea for an image analysis workshop? Share it at Halfway to I2K: Online Tutorials on Image Analysis (Nov 17–19, 2025), held with Zoom Events!
Submit by Oct 31: buff.ly/lMhK4vz
Website: buff.ly/QP36RZB
Register for the workshops: buff.ly/8nNAI18
Reposted by Gonzalo Aparicio
PREPRINT OUT ✨ "hack" your microscope to work as a 3D printer! print micrometer sized features at cm scale. a method for easy and cheap microfabrication, with a focus on biological applications. THREAD ↓
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
February 23, 2025 at 2:06 PM
PREPRINT OUT ✨ "hack" your microscope to work as a 3D printer! print micrometer sized features at cm scale. a method for easy and cheap microfabrication, with a focus on biological applications. THREAD ↓
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Gonzalo Aparicio
👃Sniffing out olfactory neurogenesis
New ‘Show and tell’ post on the Node from Sriivatsan G Rajan and Ankur Saxena @saxenalab.bsky.social:
thenode.biologists.com/sniffing-out...
#zebrafish #devbio #neurogenesis
New ‘Show and tell’ post on the Node from Sriivatsan G Rajan and Ankur Saxena @saxenalab.bsky.social:
thenode.biologists.com/sniffing-out...
#zebrafish #devbio #neurogenesis
October 22, 2025 at 2:13 PM
👃Sniffing out olfactory neurogenesis
New ‘Show and tell’ post on the Node from Sriivatsan G Rajan and Ankur Saxena @saxenalab.bsky.social:
thenode.biologists.com/sniffing-out...
#zebrafish #devbio #neurogenesis
New ‘Show and tell’ post on the Node from Sriivatsan G Rajan and Ankur Saxena @saxenalab.bsky.social:
thenode.biologists.com/sniffing-out...
#zebrafish #devbio #neurogenesis
Reposted by Gonzalo Aparicio
Colorful collage of abnormal larval zebrafish hearts. Credit to @dorotheeb.bsky.social. #ZebrafishZunday 🧪
October 19, 2025 at 1:24 PM
Colorful collage of abnormal larval zebrafish hearts. Credit to @dorotheeb.bsky.social. #ZebrafishZunday 🧪
Reposted by Gonzalo Aparicio
Finally, someone has solved a real problem with AI! No more having to take a paper in the format for a journal that rejected you, and reformat it for a new journal. Well done!! formatmypaper.com
October 15, 2025 at 6:33 AM
Finally, someone has solved a real problem with AI! No more having to take a paper in the format for a journal that rejected you, and reformat it for a new journal. Well done!! formatmypaper.com
Reposted by Gonzalo Aparicio
BIG ANNOUNCEMENT📣: I haven’t been this excited to be part of something new in 15 years… Thrilled to reveal the passion project I’ve been working on for the past year and a half!🙀🥳 (thread 👇)
October 15, 2025 at 12:22 PM
BIG ANNOUNCEMENT📣: I haven’t been this excited to be part of something new in 15 years… Thrilled to reveal the passion project I’ve been working on for the past year and a half!🙀🥳 (thread 👇)
Reposted by Gonzalo Aparicio
6/ You can do so much with it! Here are some case studies:
Demo 1: stretch the endoderm (ventral epithelium of the developing amniote 🐣 embryo, here in 🟢) → observe mechanical coupling with the subjacent mesoderm (brightfield ⬜) 🎥
Demo 1: stretch the endoderm (ventral epithelium of the developing amniote 🐣 embryo, here in 🟢) → observe mechanical coupling with the subjacent mesoderm (brightfield ⬜) 🎥
October 12, 2025 at 12:51 PM
6/ You can do so much with it! Here are some case studies:
Demo 1: stretch the endoderm (ventral epithelium of the developing amniote 🐣 embryo, here in 🟢) → observe mechanical coupling with the subjacent mesoderm (brightfield ⬜) 🎥
Demo 1: stretch the endoderm (ventral epithelium of the developing amniote 🐣 embryo, here in 🟢) → observe mechanical coupling with the subjacent mesoderm (brightfield ⬜) 🎥
Reposted by Gonzalo Aparicio
Fish keratocytes isolated from a fish scale crawling around. Technique: DIC microscopy. #CellBiology.
Another #NikonSmallWorldReject
Another #NikonSmallWorldReject
October 11, 2025 at 8:14 PM
Fish keratocytes isolated from a fish scale crawling around. Technique: DIC microscopy. #CellBiology.
Another #NikonSmallWorldReject
Another #NikonSmallWorldReject
Reposted by Gonzalo Aparicio
Published October 25 years ago, “Effective targeted gene ‘knockdown’ in zebrafish” by Nasevicius & Ekker detail use of antisense morpholino-modified oligonucelotides or #morpholinos that inhibit translation. This landmark spurred a revolution in targeted gene knockdown in vivo. #ZebrafishFunFacts 🧪
October 11, 2025 at 11:44 AM
Published October 25 years ago, “Effective targeted gene ‘knockdown’ in zebrafish” by Nasevicius & Ekker detail use of antisense morpholino-modified oligonucelotides or #morpholinos that inhibit translation. This landmark spurred a revolution in targeted gene knockdown in vivo. #ZebrafishFunFacts 🧪
Reposted by Gonzalo Aparicio
It is with great sadness that we share the news of the death of our founder, colleague, mentor and friend, Professor Sir John Gurdon. His vision and dedication will continue to inspire generations of scientists.
🔗 www.gurdon.cam.ac.uk/nobel-laurea...
🔗 www.gurdon.cam.ac.uk/nobel-laurea...
October 8, 2025 at 1:15 PM
It is with great sadness that we share the news of the death of our founder, colleague, mentor and friend, Professor Sir John Gurdon. His vision and dedication will continue to inspire generations of scientists.
🔗 www.gurdon.cam.ac.uk/nobel-laurea...
🔗 www.gurdon.cam.ac.uk/nobel-laurea...
Reposted by Gonzalo Aparicio
🧬🔬🧪 🎉 Our team at @czbiohub is thrilled to share TWO companion papers out today in @NatureMethods!
📦 Ultrack — robust, scalable nD cell tracking
🌐 inTRACKtive — a beautiful, open-source web viewer for lineage exploration
Let’s dive in! 👇
www.nature.com/articles/s41...
www.nature.com/articles/s41...
📦 Ultrack — robust, scalable nD cell tracking
🌐 inTRACKtive — a beautiful, open-source web viewer for lineage exploration
Let’s dive in! 👇
www.nature.com/articles/s41...
www.nature.com/articles/s41...
August 25, 2025 at 9:06 AM
🧬🔬🧪 🎉 Our team at @czbiohub is thrilled to share TWO companion papers out today in @NatureMethods!
📦 Ultrack — robust, scalable nD cell tracking
🌐 inTRACKtive — a beautiful, open-source web viewer for lineage exploration
Let’s dive in! 👇
www.nature.com/articles/s41...
www.nature.com/articles/s41...
📦 Ultrack — robust, scalable nD cell tracking
🌐 inTRACKtive — a beautiful, open-source web viewer for lineage exploration
Let’s dive in! 👇
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Gonzalo Aparicio
I’m happy to share some plugins I’ve been developping this summer: "Channels and Contrast" and LUTs Manager!
I can’t find new bugs and ideas by now so I need your help to please test them in your machines and report bugs, feedbacks and ideas! forum.image.sc/t/looking-fo...
I can’t find new bugs and ideas by now so I need your help to please test them in your machines and report bugs, feedbacks and ideas! forum.image.sc/t/looking-fo...
October 4, 2025 at 11:50 AM
I’m happy to share some plugins I’ve been developping this summer: "Channels and Contrast" and LUTs Manager!
I can’t find new bugs and ideas by now so I need your help to please test them in your machines and report bugs, feedbacks and ideas! forum.image.sc/t/looking-fo...
I can’t find new bugs and ideas by now so I need your help to please test them in your machines and report bugs, feedbacks and ideas! forum.image.sc/t/looking-fo...
Reposted by Gonzalo Aparicio
Reposted by Gonzalo Aparicio
Sea urchin metamorphosis is maybe one of the most radical event in developmental biology. In just about an hour, these little pluteus larvae completely reorganize their entire body plan.
Very happy that this video got awarded an honorable mention by #NikonSmallWorld 😃
Very happy that this video got awarded an honorable mention by #NikonSmallWorld 😃
September 26, 2025 at 12:56 AM
Sea urchin metamorphosis is maybe one of the most radical event in developmental biology. In just about an hour, these little pluteus larvae completely reorganize their entire body plan.
Very happy that this video got awarded an honorable mention by #NikonSmallWorld 😃
Very happy that this video got awarded an honorable mention by #NikonSmallWorld 😃
Reposted by Gonzalo Aparicio
”Please inhibit responsibly: Natural and synthetic actin toxins as useful tools in cell biology”
I had a lot of fun going down different actin inhibitor rabbit holes with @onishilab.bsky.social on this perspective!
www.molbiolcell.org/doi/10.1091/...
www.molbiolcell.org/cms/10.1091/...
I had a lot of fun going down different actin inhibitor rabbit holes with @onishilab.bsky.social on this perspective!
www.molbiolcell.org/doi/10.1091/...
www.molbiolcell.org/cms/10.1091/...
September 16, 2025 at 1:31 AM
”Please inhibit responsibly: Natural and synthetic actin toxins as useful tools in cell biology”
I had a lot of fun going down different actin inhibitor rabbit holes with @onishilab.bsky.social on this perspective!
www.molbiolcell.org/doi/10.1091/...
www.molbiolcell.org/cms/10.1091/...
I had a lot of fun going down different actin inhibitor rabbit holes with @onishilab.bsky.social on this perspective!
www.molbiolcell.org/doi/10.1091/...
www.molbiolcell.org/cms/10.1091/...
Reposted by Gonzalo Aparicio
Researchers have filmed thousands of climbing catfish scaling waterfalls, providing a rare insight into the daring migration of an enigmatic fish.
Learn more: https://scim.ag/4lDlFux
Learn more: https://scim.ag/4lDlFux
August 22, 2025 at 1:48 PM
Researchers have filmed thousands of climbing catfish scaling waterfalls, providing a rare insight into the daring migration of an enigmatic fish.
Learn more: https://scim.ag/4lDlFux
Learn more: https://scim.ag/4lDlFux
Reposted by Gonzalo Aparicio
Are different cell types like oil and water? Over a century ago, researchers found that dissociated sponges and embryonic tissues can self-assemble into functional structures. Join me, @benswedlund.bsky.social to explore the differential adhesion hypothesis & its applications in tissue engineering!
August 31, 2025 at 12:00 PM
Are different cell types like oil and water? Over a century ago, researchers found that dissociated sponges and embryonic tissues can self-assemble into functional structures. Join me, @benswedlund.bsky.social to explore the differential adhesion hypothesis & its applications in tissue engineering!
Reposted by Gonzalo Aparicio
¡Qué lindo!
Every bit of this south wall in the #MarDelPlataCanyon is vibrant and alive. Read and imagine how a tiny sponge larva or other stationary animal finds a home in a place like this: www.instagram.com/reel/DN37jxs...
Every bit of this south wall in the #MarDelPlataCanyon is vibrant and alive. Read and imagine how a tiny sponge larva or other stationary animal finds a home in a place like this: www.instagram.com/reel/DN37jxs...
August 27, 2025 at 10:37 PM
¡Qué lindo!
Every bit of this south wall in the #MarDelPlataCanyon is vibrant and alive. Read and imagine how a tiny sponge larva or other stationary animal finds a home in a place like this: www.instagram.com/reel/DN37jxs...
Every bit of this south wall in the #MarDelPlataCanyon is vibrant and alive. Read and imagine how a tiny sponge larva or other stationary animal finds a home in a place like this: www.instagram.com/reel/DN37jxs...
Reposted by Gonzalo Aparicio
La luna terminando su jornada con una sonrisa, sobre el Cerro de Montevideo
August 27, 2025 at 12:08 AM
La luna terminando su jornada con una sonrisa, sobre el Cerro de Montevideo