flymuscles
@flymuscles.bsky.social
Assistant professor @Dalhousie University in Canada. We study # muscle function in #Drosophila. I bike to work.
https://flymuscles.wixsite.com/flymuscles
https://flymuscles.wixsite.com/flymuscles
Reposted by flymuscles
You must have been looking forward to... October in preprints!
Check out the latest #preprints on #DevBio, #StemCell biology and related topics with, starting this month, @prelights.bsky.social picks 👇👀
thenode.biologists.com/october-in-p...
Check out the latest #preprints on #DevBio, #StemCell biology and related topics with, starting this month, @prelights.bsky.social picks 👇👀
thenode.biologists.com/october-in-p...
October in preprints - the Node
Welcome to our monthly trawl for developmental and stem cell biology (and related) preprints. The preprints this month are hosted on bioRxiv.
thenode.biologists.com
November 13, 2025 at 12:30 PM
You must have been looking forward to... October in preprints!
Check out the latest #preprints on #DevBio, #StemCell biology and related topics with, starting this month, @prelights.bsky.social picks 👇👀
thenode.biologists.com/october-in-p...
Check out the latest #preprints on #DevBio, #StemCell biology and related topics with, starting this month, @prelights.bsky.social picks 👇👀
thenode.biologists.com/october-in-p...
Reposted by flymuscles
Reposted by flymuscles
Poniendo los puntos sobre las íes 👏
Beigel, F., Brockington, D., Crosetto, P., Derrick, G., Fyfe, A., Barreiro, P. G., Hanson, M. A., Haustein, S., Larivière, V., Noe, C., Pinfield, S., & Wilsdon, J. (2025). The Drain of Scientific Publishing (No. arXiv:2511.04820). arXiv. doi.org/10.48550/arX...
Beigel, F., Brockington, D., Crosetto, P., Derrick, G., Fyfe, A., Barreiro, P. G., Hanson, M. A., Haustein, S., Larivière, V., Noe, C., Pinfield, S., & Wilsdon, J. (2025). The Drain of Scientific Publishing (No. arXiv:2511.04820). arXiv. doi.org/10.48550/arX...
The Drain of Scientific Publishing
The domination of scientific publishing in the Global North by major commercial publishers is harmful to science. We need the most powerful members of the research community, funders, governments and ...
doi.org
November 10, 2025 at 5:19 PM
Poniendo los puntos sobre las íes 👏
Beigel, F., Brockington, D., Crosetto, P., Derrick, G., Fyfe, A., Barreiro, P. G., Hanson, M. A., Haustein, S., Larivière, V., Noe, C., Pinfield, S., & Wilsdon, J. (2025). The Drain of Scientific Publishing (No. arXiv:2511.04820). arXiv. doi.org/10.48550/arX...
Beigel, F., Brockington, D., Crosetto, P., Derrick, G., Fyfe, A., Barreiro, P. G., Hanson, M. A., Haustein, S., Larivière, V., Noe, C., Pinfield, S., & Wilsdon, J. (2025). The Drain of Scientific Publishing (No. arXiv:2511.04820). arXiv. doi.org/10.48550/arX...
Reposted by flymuscles
Glad to share our latest work showing that #drosophila epigenetic enzyme TET controls muscle development independently of its catalytic activity but prevents muscle aging in a catalytic-dependent manner!
Congratulations to Vincent and Emilie @igred.fr !
links.springernature.com/f/a/L1ogzL3H...
Congratulations to Vincent and Emilie @igred.fr !
links.springernature.com/f/a/L1ogzL3H...
TET exhibits enzymatic-independent and-dependent functions during Drosophila flight muscle development and aging - Skeletal Muscle
Background Enzymes of the Ten-Eleven Translocation family are responsible for 5-methylcytosine (5mC) oxidation and play a key role in regulating DNA demethylation during various developmental processe...
links.springernature.com
October 27, 2025 at 3:23 PM
Glad to share our latest work showing that #drosophila epigenetic enzyme TET controls muscle development independently of its catalytic activity but prevents muscle aging in a catalytic-dependent manner!
Congratulations to Vincent and Emilie @igred.fr !
links.springernature.com/f/a/L1ogzL3H...
Congratulations to Vincent and Emilie @igred.fr !
links.springernature.com/f/a/L1ogzL3H...
Reposted by flymuscles
Reposted by flymuscles
Nope. Read his words compiled by @lpachter.bsky.social and say that again. He was a stain on science from day 1
liorpachter.wordpress.com/2018/05/18/j...
liorpachter.wordpress.com/2018/05/18/j...
James Watson in his own words
“Some anti-Semitism is justified” “Whenever you interview fat people, you feel bad, because you know you’re not going to hire them” “Japan should be bombed for d…
liorpachter.wordpress.com
November 8, 2025 at 2:30 PM
Nope. Read his words compiled by @lpachter.bsky.social and say that again. He was a stain on science from day 1
liorpachter.wordpress.com/2018/05/18/j...
liorpachter.wordpress.com/2018/05/18/j...
lol so true
I didn't realize it was possible but those weird impersonal marketing spam e-mails have somehow gotten even more depressing now that they're being written by LLMs. At least before it was an actual human pretending to be interested in my work!
November 4, 2025 at 5:12 PM
lol so true
Reposted by flymuscles
A threshold level of JNK activates damage-responsive enhancers via JAK/STAT to promote tissue regeneration
Read this #LifelongDevSI #OA Research Article by John W. Quinn, Robin E. Harris and colleagues in our Stem Cells and Regeneration section doi.org/10.1242/dev....
Read this #LifelongDevSI #OA Research Article by John W. Quinn, Robin E. Harris and colleagues in our Stem Cells and Regeneration section doi.org/10.1242/dev....
October 31, 2025 at 5:53 PM
A threshold level of JNK activates damage-responsive enhancers via JAK/STAT to promote tissue regeneration
Read this #LifelongDevSI #OA Research Article by John W. Quinn, Robin E. Harris and colleagues in our Stem Cells and Regeneration section doi.org/10.1242/dev....
Read this #LifelongDevSI #OA Research Article by John W. Quinn, Robin E. Harris and colleagues in our Stem Cells and Regeneration section doi.org/10.1242/dev....
We desperately needed a cooling dry bath, but the typical brands are crazy expensive. So we got ourselves a
October 30, 2025 at 7:10 PM
We desperately needed a cooling dry bath, but the typical brands are crazy expensive. So we got ourselves a
Reposted by flymuscles
PAPER OUT ✨ What if you could use your microscope as a 3D printer? Prototype microfluidics in-house, <5$ in material costs per chip. From idea to experiment within a day. Now published in Lab-on-a-Chip (open-access): doi.org/10.1039/D5LC...
July 16, 2025 at 11:51 AM
PAPER OUT ✨ What if you could use your microscope as a 3D printer? Prototype microfluidics in-house, <5$ in material costs per chip. From idea to experiment within a day. Now published in Lab-on-a-Chip (open-access): doi.org/10.1039/D5LC...
Reposted by flymuscles
Nature Communications will publish ~10K papers in 2025 pubmed.ncbi.nlm.nih.gov?term=%22Natu...
That's ~$70M in revenue, while many of the non-profit journals that used to occupy that slot in the journal hierarchy have seen a precipitous decline in submissions in the 15 years it's existed.
That's ~$70M in revenue, while many of the non-profit journals that used to occupy that slot in the journal hierarchy have seen a precipitous decline in submissions in the 15 years it's existed.
October 27, 2025 at 8:38 PM
Nature Communications will publish ~10K papers in 2025 pubmed.ncbi.nlm.nih.gov?term=%22Natu...
That's ~$70M in revenue, while many of the non-profit journals that used to occupy that slot in the journal hierarchy have seen a precipitous decline in submissions in the 15 years it's existed.
That's ~$70M in revenue, while many of the non-profit journals that used to occupy that slot in the journal hierarchy have seen a precipitous decline in submissions in the 15 years it's existed.
Reposted by flymuscles
Meet Dr. Angelo Iulianella! @aineurolab.bsky.social "My interests are varied, perhaps a bit too varied, but my curiosity is always tickled by some new facts revealed to me by my fellow members at the AAA."
Want to be featured? Fill out this form 👉 ow.ly/iLiu50XcC6Q
#AAA #FacesofAnatomy
Want to be featured? Fill out this form 👉 ow.ly/iLiu50XcC6Q
#AAA #FacesofAnatomy
October 22, 2025 at 6:48 PM
Meet Dr. Angelo Iulianella! @aineurolab.bsky.social "My interests are varied, perhaps a bit too varied, but my curiosity is always tickled by some new facts revealed to me by my fellow members at the AAA."
Want to be featured? Fill out this form 👉 ow.ly/iLiu50XcC6Q
#AAA #FacesofAnatomy
Want to be featured? Fill out this form 👉 ow.ly/iLiu50XcC6Q
#AAA #FacesofAnatomy
Reposted by flymuscles
Lab’s first paper is out!! We show the first structures of #Asgard #chromatin by #cryo-EM 🧬❄️
Asgard histones form closed and open hypernucleosomes. Closed are conserved across #Archaea, while open resemble eukaryotic H3–H4 octasomes and are Asgard-specific. More here: www.cell.com/molecular-ce...
Asgard histones form closed and open hypernucleosomes. Closed are conserved across #Archaea, while open resemble eukaryotic H3–H4 octasomes and are Asgard-specific. More here: www.cell.com/molecular-ce...
October 28, 2025 at 3:07 PM
Lab’s first paper is out!! We show the first structures of #Asgard #chromatin by #cryo-EM 🧬❄️
Asgard histones form closed and open hypernucleosomes. Closed are conserved across #Archaea, while open resemble eukaryotic H3–H4 octasomes and are Asgard-specific. More here: www.cell.com/molecular-ce...
Asgard histones form closed and open hypernucleosomes. Closed are conserved across #Archaea, while open resemble eukaryotic H3–H4 octasomes and are Asgard-specific. More here: www.cell.com/molecular-ce...
Reposted by flymuscles
Plant bioengineering is so cool.
October 26, 2025 at 5:45 AM
Plant bioengineering is so cool.
Reposted by flymuscles
- "Raise the East Wing" ! (only for ♂♂)(and drosophilists).
October 26, 2025 at 8:20 AM
- "Raise the East Wing" ! (only for ♂♂)(and drosophilists).
Reposted by flymuscles
What are these?
You are looking at embryos of a sea squirt. Each of the 'soap bubbles' is a living cell, about a fourtieth of a millimetre in size. The outlines of the cells are visible thanks to fluorescent markers identified by Hitoyoshi Yasuo @hitoyas.bsky.social
see doi.org/10.1101/2024... 🧵
You are looking at embryos of a sea squirt. Each of the 'soap bubbles' is a living cell, about a fourtieth of a millimetre in size. The outlines of the cells are visible thanks to fluorescent markers identified by Hitoyoshi Yasuo @hitoyas.bsky.social
see doi.org/10.1101/2024... 🧵
October 26, 2025 at 8:55 AM
What are these?
You are looking at embryos of a sea squirt. Each of the 'soap bubbles' is a living cell, about a fourtieth of a millimetre in size. The outlines of the cells are visible thanks to fluorescent markers identified by Hitoyoshi Yasuo @hitoyas.bsky.social
see doi.org/10.1101/2024... 🧵
You are looking at embryos of a sea squirt. Each of the 'soap bubbles' is a living cell, about a fourtieth of a millimetre in size. The outlines of the cells are visible thanks to fluorescent markers identified by Hitoyoshi Yasuo @hitoyas.bsky.social
see doi.org/10.1101/2024... 🧵
obviously a very bad metric.
but why is nature publishing click-bait news like this?
but why is nature publishing click-bait news like this?
Google Scholar has introduced a 'Sh-index' metric that scores papers higher if you are first or last author. Apart from the fact metrics are generally bad, this one explicitly punishes PIs who often collaborate, publishing with 2 or 3 equal PIs at the end of the list.
www.nature.com/articles/d41...
www.nature.com/articles/d41...
Google Scholar tool gives extra credit to first and last authors
Researchers welcome the initiative, but say it doesn’t go far enough to capture the nuance of researcher productivity and impact.
www.nature.com
October 26, 2025 at 12:41 PM
obviously a very bad metric.
but why is nature publishing click-bait news like this?
but why is nature publishing click-bait news like this?
www.nature.com/articles/s41...
Probably has been shared a few times already, but I just read this beautiful work.
The tip of the Malpighian tubules is the calcium storage in #Drosophila (and insects?), and the hormone that regulates the release is called Capability (Capa).
Probably has been shared a few times already, but I just read this beautiful work.
The tip of the Malpighian tubules is the calcium storage in #Drosophila (and insects?), and the hormone that regulates the release is called Capability (Capa).
Neuroendocrine control of calcium mobilization in the fruit fly - Nature
The peptide hormone Capa is responsible for regulating extracellular fluid Ca2+ levels in the fruit fly Drosophila melanogaster.
www.nature.com
October 26, 2025 at 12:51 AM
www.nature.com/articles/s41...
Probably has been shared a few times already, but I just read this beautiful work.
The tip of the Malpighian tubules is the calcium storage in #Drosophila (and insects?), and the hormone that regulates the release is called Capability (Capa).
Probably has been shared a few times already, but I just read this beautiful work.
The tip of the Malpighian tubules is the calcium storage in #Drosophila (and insects?), and the hormone that regulates the release is called Capability (Capa).
Reposted by flymuscles
Cited4a limits cardiomyocyte dedifferentiation and proliferation during zebrafish heart regeneration
Read this #LifelongDevSI #OA Research Article by Rachel Forman-Rubinsky, Michael Tsang and colleagues from the University of Pittsburgh
doi.org/10.1242/dev....
Read this #LifelongDevSI #OA Research Article by Rachel Forman-Rubinsky, Michael Tsang and colleagues from the University of Pittsburgh
doi.org/10.1242/dev....
October 23, 2025 at 3:57 PM
Cited4a limits cardiomyocyte dedifferentiation and proliferation during zebrafish heart regeneration
Read this #LifelongDevSI #OA Research Article by Rachel Forman-Rubinsky, Michael Tsang and colleagues from the University of Pittsburgh
doi.org/10.1242/dev....
Read this #LifelongDevSI #OA Research Article by Rachel Forman-Rubinsky, Michael Tsang and colleagues from the University of Pittsburgh
doi.org/10.1242/dev....
Reposted by flymuscles
Dick is one of the most thoughtful folks in cell biology--this is a must read for anyone interested in microtubules!
Perspective from Richard McIntosh describing the history of research on #microtubule polymerization in terms of the ideas, technologies, and observations that have emerged as countless researchers have studied the dynamics of these essential cytoskeletal polymers. rupress.org/jcb/article/...
October 15, 2025 at 6:23 PM
Dick is one of the most thoughtful folks in cell biology--this is a must read for anyone interested in microtubules!
Reposted by flymuscles
Happy birthday @biologists.bsky.social! 🥳 Here’s to another century of supporting biologists and inspiring biology!
1925: On this date, 100 years ago, The Company of Biologists is founded by George Parker Bidder III. Throughout today, we will be posting some of our key milestones. Read more about the past 100 years at bit.ly/3WnTVA1.
October 15, 2025 at 8:32 AM
Happy birthday @biologists.bsky.social! 🥳 Here’s to another century of supporting biologists and inspiring biology!
Reposted by flymuscles
We are pleased to announce that the 2nd DrosoSpain meeting #DrosoSpain2026 will take place in San Joan de Alicante from the 9th to the 11th of April 2026 #savethedate
October 13, 2025 at 8:20 PM
We are pleased to announce that the 2nd DrosoSpain meeting #DrosoSpain2026 will take place in San Joan de Alicante from the 9th to the 11th of April 2026 #savethedate
Reposted by flymuscles
Reposted by flymuscles
📢 latest from the PowerLab🚨
app.jove.com/t/68858/cons...
Step by step guide on Construction of Constant-Load (Isotonic) and Constant-Velocity (Isokinetic) Torque-Velocity-Power Profiles In vivo for the Rat Plantar Flexors
Video to follow!
app.jove.com/t/68858/cons...
Step by step guide on Construction of Constant-Load (Isotonic) and Constant-Velocity (Isokinetic) Torque-Velocity-Power Profiles In vivo for the Rat Plantar Flexors
Video to follow!
Construction of Constant-Load (Isotonic) and Constant-Velocity (Isokinetic) Torque-Velocity-Power Profiles In vivo for the Rat Plantar Flexors
University of Guelph. Here, we present a novel protocol to non-invasively measure the torque-angular velocity-power relationship in vivo in rat plantar flexors using transcutaneous muscle stimulation...
app.jove.com
October 7, 2025 at 1:48 PM
📢 latest from the PowerLab🚨
app.jove.com/t/68858/cons...
Step by step guide on Construction of Constant-Load (Isotonic) and Constant-Velocity (Isokinetic) Torque-Velocity-Power Profiles In vivo for the Rat Plantar Flexors
Video to follow!
app.jove.com/t/68858/cons...
Step by step guide on Construction of Constant-Load (Isotonic) and Constant-Velocity (Isokinetic) Torque-Velocity-Power Profiles In vivo for the Rat Plantar Flexors
Video to follow!
Reposted by flymuscles
🪰 A team of researchers has unveiled the complete connectome of a male fruit fly central nervous system—a seamless map of all the neurons in the brain and nerve cord of a single male fruit fly and the millions of connections between them.
🔗 https://hhmi.news/4o3EJnk
🔗 https://hhmi.news/4o3EJnk
October 6, 2025 at 2:16 PM
🪰 A team of researchers has unveiled the complete connectome of a male fruit fly central nervous system—a seamless map of all the neurons in the brain and nerve cord of a single male fruit fly and the millions of connections between them.
🔗 https://hhmi.news/4o3EJnk
🔗 https://hhmi.news/4o3EJnk